Addresses the fundamental mechanisms by which environmental exposures combine with genetic susceptibility to influence risk of complex human diseases and disorders.
Builds on evolving knowledge in the fields of genomics and epigenomics to understand mechanisms that act at the interface of genes and environment to influence gene activity and phenotype.
Emphasizes laboratory-based studies in model systems at the cellular, organ and system level.
In 2012, with the help of our stakeholders, NIEHS completed a new strategic plan that identified the institute’s priority research areas through 2017. The GEH goals align broadly with the following strategic plan goals: