Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Spatiotemporal Exposures and Toxicology Group
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Kyle P. Messier, Ph.D.
Stadtman Investigator;
Leader, Spatiotemporal Exposures and Toxicology
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Tel 984-287-3215
[email protected]
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530 Davis Dr
530 Davis Drive (Keystone Bldg)
Durham, NC 27713
Kyle Messier is a Stadtman Tenure-Track Investigator at the National Institute of Environmental Health Sciences (NIEHS) in the Division of Translational Toxicology (DTT). He leads the Spatiotemporal Exposures and Toxicology group, within the Predictive Toxicology Branch.
The group, has a broad interest in geospatial exposomics and risk mapping. Key areas of research include (1) Spatiotemporal exposure mapping of environmental and climate variables (e.g. chemical mixtures, social, behavioral, environmental, and climate factors); (2) Source-to-outcome modeling, or GeoTox, which is the integration of geospatial exposures, toxicokinetic modeling, and non-animal toxicological data such as high-through in vitro screen assays to develop mechanistically-informed risk maps; and (3) Developing and promoting software and computational best-practices such as open-source code for the environmental health sciences.”
Recent Publications
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Zilber D, Messier K. Reflected generalized concentration addition and Bayesian hierarchical models to improve chemical mixture prediction.
PloS one.
2024;19(3):e0298687.
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AbstractZilber D, Messier K. Reflected generalized concentration addition and Bayesian hierarchical models to improve chemical mixture prediction. PloS one. 2024
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Messier K, Reif D, Marvel S. The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk.
medRxiv : the preprint server for health sciences.
2024 Nov 20 [Epub ahead of print].
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AbstractMessier K, Reif D, Marvel S. The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk. medRxiv : the preprint server for health sciences. 2024 Nov 20
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Sheng A, Reich B, Messier K. Associations between flood risk and US Census tract-level health outcomes.
American journal of epidemiology.
2024 Oct 07;193(10):1384-1391.
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AbstractSheng A, Reich B, Messier K. Associations between flood risk and US Census tract-level health outcomes. American journal of epidemiology. 2024 Oct 07
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Clark L, Zilber D, Schmitt C, Fargo D, Reif D, Motsinger-Reif A, Messier K. A review of geospatial exposure models and approaches for health data integration.
Journal of exposure science & environmental epidemiology.
2024 Sep 06 [Epub ahead of print].
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AbstractClark L, Zilber D, Schmitt C, Fargo D, Reif D, Motsinger-Reif A, Messier K. A review of geospatial exposure models and approaches for health data integration. Journal of exposure science & environmental epidemiology. 2024 Sep 06
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Motsinger-Reif A, Reif D, Akhtari F, House J, Campbell C, Messier K, Fargo D, Bowen T, Nadadur S, Schmitt C, Pettibone K, Balshaw D, Lawler C, Newton S, Collman G, Miller A, Merrick B, Cui Y, Anchang B, Harmon Q, McAllister K, Woychik R. Gene-environment interactions within a precision environmental health framework.
Cell genomics.
2024 Jul 10;4(7):100591.
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AbstractMotsinger-Reif A, Reif D, Akhtari F, House J, Campbell C, Messier K, Fargo D, Bowen T, Nadadur S, Schmitt C, Pettibone K, Balshaw D, Lawler C, Newton S, Collman G, Miller A, Merrick B, Cui Y, Anchang B, Harmon Q, McAllister K, Woychik R. Gene-environment interactions within a precision environmental health framework. Cell genomics. 2024 Jul 10
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More Recent Publications from PubMed
