Purpose

You may use this R code for fitting the Random Periods Model (RPM) for cell cycle genes. Since outliers and influential observations are not uncommon, the parameters of RPM are estimated using the L_1 norm. The RPM is a nonlinear model that can be used to model the expression of a cell-cycle gene over time. For details regarding the model one may refer to Liu et al. (2004).

Software info

Details on how to use is provided in the How to Use R code for Fitting Random Periods Model webpage.

References

Liu D, Umbach D, Peddada SD, Li L, Crockett P and Weinberg C (2004). A Random-Periods Model for Expression of Cell-Cycle Genes. Proceedings of National Academy of Sciences, 101, No. 19, 7240-7245.

Download

CCOptimF.R (2KB) 

Contact

Clarice R. Weinberg, Ph.D.
Principal Investigator

Tel 984-287-3697
[email protected]