Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
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Sonika Patial, D.V.M., Ph.D., D.A.C.V.P.
Scientist - Pathologist
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Tel 240-921-0904
[email protected]
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111 Tw Alexander Dr
Research Triangle Park, NC 27709
Sonika Patial is a Scientist / Pathologist in the Comparative and Molecular Pathogenesis Branch (CMPB) in the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences (NIEHS). Additionally, she is an adjunct Associate Professor in the Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University.
Dr. Patial received her Doctor of Veterinary Medicine degree from The College of Veterinary and Animal Sciences, Palampur, India (2003); her Master of Veterinary Science in Animal Biotechnology from Indian Veterinary Research Institute, Izatnagar, India (2005); and her PhD from Michigan State University, East Lansing (2010). She completed her Veterinary Anatomic Pathology residency training from Louisiana State University, Baton Rouge (2016). Dr. Patial is a diplomate of the American College of Veterinary Pathologists.
Before joining DTT, Dr. Patial was a tenure-track Assistant Professor in the Department of Comparative Biomedical Sciences in the LSU School of Veterinary Medicine (2017-2022), where she established an independent research program focused on investigating the molecular mechanisms underlying environmentally induced inflammatory diseases of the lung. During her tenure, she secured significant research funding, including an R01 grant, and received several accolades, such as the ASIP Early Career Investigator Award, the Lung COBRE Investigator Award, multiple placements on the Dean’s Teacher Merit Honor Roll, and the LSU Alumni Association Rising Faculty Research Award. Dr. Patial's contributions to the field include multiple peer-reviewed publications, teaching and mentoring, and invited talks, demonstrating her expertise in both research and training the next generation of scientists. Her current research interests center on understanding the molecular pathology of occupational and environmentally induced pathologies particularly the impact of environment on chemical exposures and their contribution to respiratory health and chronic respiratory diseases.
Recent Publications
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Mao Y, Suryawanshi A, Patial S, Saini Y. Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease.
Frontiers in pharmacology.
2024;15:1460692.
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AbstractMao Y, Suryawanshi A, Patial S, Saini Y. Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease. Frontiers in pharmacology. 2024
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Vo T, Kumar R, Lamichhane R, Choudhary I, Kc R, Mao Y, Paudel K, Suryawanshi A, Sharma A, Metzler M, Nolan M, Patial S, Saini Y. Protocol for X-ray irradiation of C57BL/6J recipient mice followed by the transplantation of mTomato-expressing bone marrow cells.
STAR protocols.
2024 Dec 18;6(1):103504.
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AbstractVo T, Kumar R, Lamichhane R, Choudhary I, Kc R, Mao Y, Paudel K, Suryawanshi A, Sharma A, Metzler M, Nolan M, Patial S, Saini Y. Protocol for X-ray irradiation of C57BL/6J recipient mice followed by the transplantation of mTomato-expressing bone marrow cells. STAR protocols. 2024 Dec 18
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Choudhary I, Lamichhane R, Singamsetty D, Vo T, Brombacher F, Patial S, Saini Y. Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease.
American journal of respiratory cell and molecular biology.
2024 Dec;71(6):702-717.
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AbstractChoudhary I, Lamichhane R, Singamsetty D, Vo T, Brombacher F, Patial S, Saini Y. Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease. American journal of respiratory cell and molecular biology. 2024 Dec
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Paudel S, Kumar R, Rogers K, Saini Y, Patial S, Kulkarni R. The NLRP3 Inflammasome Is Dispensable in Methicillin-Resistant Staphylococcus aureus Urinary Tract Infection.
Pathogens (Basel, Switzerland).
2024 Jan 25;13(2):.
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AbstractPaudel S, Kumar R, Rogers K, Saini Y, Patial S, Kulkarni R. The NLRP3 Inflammasome Is Dispensable in Methicillin-Resistant Staphylococcus aureus Urinary Tract Infection. Pathogens (Basel, Switzerland). 2024 Jan 25
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Bathula C, Chen J, Kumar R, Blackshear P, Saini Y, Patial S. ZFP36L1 Regulates Fgf21 mRNA Turnover and Modulates Alcoholic Hepatic Steatosis and Inflammation in Mice.
The American journal of pathology.
2022 Feb;192(2):208-225.
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AbstractBathula C, Chen J, Kumar R, Blackshear P, Saini Y, Patial S. ZFP36L1 Regulates Fgf21 mRNA Turnover and Modulates Alcoholic Hepatic Steatosis and Inflammation in Mice. The American journal of pathology. 2022 Feb
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More Recent Publications from PubMed