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About the Platform

We offer a targeted lipidomics method as our preferred tool for investigating lipids in disease-associated systems. This broad targeted approach leverages a conserved chemical logic of glycerolipids, sphingolipids, and sterols to measure relative levels of specific lipid molecules. We work with investigators to reach a clear, directed interpretation of the data. While relative quantitation often provides adequate information to resolve most lipid hypotheses, there is the possibility for pseudo-absolute quantification (quantification based on similarity to internal standards) as well as customization of the panel. Please indicate in the request form the level of quantification (e.g., relative vs. pseudo-absolute) required and details can be discussed during consultation.

  • Measurement of 1750 individual lipids.
  • Acyl-chain resolution (i.e., length, number of double bonds) of phosphatidylethanolamine, phosphatidylcholine, sphingomyelin, ceramide, hexosylceramide, lactosylceramide, dihydroceramide, phosphatidylserine, phosphatidylinositol, phosphatidylglycerol, Ether-PE, triacylglycerol, diacylglycerol, monoacylglycerol, cholesterol esters, free fatty acids, and lysophospholipids.
  • Compatibility with a wide range of biological matrices.

Cost

Please consult with the NIAID Core Director for cost information.

References

Contact

Benji Schwarz, Ph.D.
Benji Schwarz, Ph.D.
Staff Scientist
Tel 406-363-9285
[email protected]