Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Hematology & Clinical Chemistry
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Greg Travlos, D.V.M., D.A.C.V.P.
Clinical Pathology Group Leader
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Tel 984-287-3826
[email protected]
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P.O. Box 12233
Mail Drop B3-06
Durham, NC 27709
Research Summary
The Clinical Pathology Group provides collaborative and consultative clinical pathology support for investigators at NIEHS. The laboratory provides basic services in hematology, clinical chemistry, and urinalysis. Special assays also have been performed including the determination of hormone, growth factor, prostaglandin and chemokine/cytokine concentrations, bone marrow cellularity and differential counts, methemoglobin concentration, b-hydroxybutyrate concentration, cholinesterase and isoenzyme evaluations.
The Clinical Pathology Group consists of the hematology and clinical chemistry laboratories and is currently staffed by two full-time NIEHS medical technologists and one on-site contract employee. Over time, considerable efforts regarding acquisition of equipment, upgrading standard operating procedures, developing historical data bases for control animals and implementing appropriate data management, quality control, quality assurance, and proficiency testing programs have been made to ensure that these laboratories continue to provide high quality hematology and clinical chemistry analyses. For almost two decades, the Clinical Pathology Group has been a valuable resource for the institute.
Gregory Travlos, D.V.M., D.A.C.V.P., leads the Clinical Pathology Group within the Cellular and Molecular Pathology Branch. He earned his D.V.M. in 1979 at Iowa State University College of Veterinary Medine. He has published numerous peer-reviewed articles in leading biomedical journals as well as several book chapters. He served as a Veterinary Clinical Pathologist and Manager of the Veterinary Division at MetPath, Inc. before joining NIEHS in 1991.
Scientists & Staff
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Greg Travlos, D.V.M., D.A.C.V.P.
Clinical Pathology Group Leader
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Tel 984-287-3826
[email protected]
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Sukhdev Brar
Biologist
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Tel 984-287-3942
[email protected]
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Michelle C. Cora, D.V.M., D.A.C.V.P.
Staff Scientist
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Tel 984-287-3828
[email protected]
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Lorri Ezedin
Contractor - Data Coordination Unit
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Tel 984-287-3830
[email protected]
Recent Publications
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Goldberg M, Adgent M, Stevens D, Chin H, Ferguson K, Calafat A, Travlos G, Ford E, Stallings V, Rogan W, Umbach D, Baird D, Sandler D. Environmental phenol exposures in 6- to 12-week-old infants: The Infant Feeding and Early Development (IFED) study.
Environmental research.
2024 Jul 01;252(Pt 4):119075.
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AbstractGoldberg M, Adgent M, Stevens D, Chin H, Ferguson K, Calafat A, Travlos G, Ford E, Stallings V, Rogan W, Umbach D, Baird D, Sandler D. Environmental phenol exposures in 6- to 12-week-old infants: The Infant Feeding and Early Development (IFED) study. Environmental research. 2024 Jul 01
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Frawley R, Johnson V, Burleson G, Shockley K, Cesta M, Travlos G, Cora M, Roberts G, Germolec D. Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28-day study.
Journal of applied toxicology : JAT.
2023 Nov;43(11):1686-1701.
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AbstractFrawley R, Johnson V, Burleson G, Shockley K, Cesta M, Travlos G, Cora M, Roberts G, Germolec D. Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28-day study. Journal of applied toxicology : JAT. 2023 Nov
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Izawa T, Travlos G, Cortes R, Clayton N, Sills R, Pandiri A. Absence of Increased Susceptibility to Acetaminophen-Induced Liver Injury in a Diet-Induced NAFLD Mouse Model.
Toxicologic pathology.
2023 Apr;51(3):112-125.
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AbstractIzawa T, Travlos G, Cortes R, Clayton N, Sills R, Pandiri A. Absence of Increased Susceptibility to Acetaminophen-Induced Liver Injury in a Diet-Induced NAFLD Mouse Model. Toxicologic pathology. 2023 Apr
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Cupul-Uicab L, Bornman R, Archer J, Kudumu M, Travlos G, Wilson R, Whitworth K. Exposure to DDT from indoor residual spraying and biomarkers of inflammation among reproductive-aged women from South Africa.
Environmental research.
2020 Dec;191:110088.
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AbstractCupul-Uicab L, Bornman R, Archer J, Kudumu M, Travlos G, Wilson R, Whitworth K. Exposure to DDT from indoor residual spraying and biomarkers of inflammation among reproductive-aged women from South Africa. Environmental research. 2020 Dec
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Frawley R, Witt K, Cunny H, Germolec D, Jackson-Humbles D, Malarkey D, Shockley K, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling G, Manheng W, Surh I, White K, Auerbach S. Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies.
Toxicology.
2020 Aug;441:152474.
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AbstractFrawley R, Witt K, Cunny H, Germolec D, Jackson-Humbles D, Malarkey D, Shockley K, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling G, Manheng W, Surh I, White K, Auerbach S. Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies. Toxicology. 2020 Aug
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More Recent Publications from PubMed