Health Scientist
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Kembra L. Howdeshell, Ph.D.
Health Scientist
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Tel 984-287-3141
[email protected]
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P.O. Box 12233
Mail Drop K2-04
Durham, NC 27709
Kembra Howdeshell, Ph.D., is a Health Scientist with the Integrated Health Assessment Branch, Division of Translational Toxicology (DTT; formerly Division of the National Toxicology Program) at the National Institute of Environmental Health Sciences. Her research interests include developmental reproductive toxicology, endocrine disruption, and mixtures toxicology. At the DTT, she conducts literature-based evaluations on the health effects of environmental exposures using systematic review methodology. Her research has focused on reproductive toxicity studies of bisphenol A and phthalate mixtures as well as systematic review evaluations on the association of occupational exposure to cancer chemotherapy use and adverse health effects and the association of traffic-related air pollution and hypertensive disorders of pregnancy as well as systematic evidence maps on personal care products and a variety of health outcomes. She collaborated with federal and academic researchers to summarize the published research from the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA), and she led a narrative review on CLARITY-BPA in the context of other BPA publications with suggestions for refining the toxicity testing of potential endocrine disrupting chemicals. Additionally, Howdeshell serves on several DTT, NIEHS, and interagency committees, including DTT's Combined Exposures and Mixtures Program.
Selected Publications
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Taylor KW, Howdeshell KL, Bommarito PA, Sibrizzi CA, Blain RB, Magnuson K, Lemeris C, Tracy W, Baird DD, Jackson CL, Gaston SA, Rider CV, Walker VR, Rooney AA. 2023. Systematic evidence mapping informs a class-based approach to assessing personal care products and pubertal timing. Environ Int 181:108307. doi: 10.1016/j.envint.2023.108307. Epub 2023 Nov 4.
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Abstract
Taylor KW, Howdeshell KL, Bommarito PA, Sibrizzi CA, Blain RB, Magnuson K, Lemeris C, Tracy W, Baird DD, Jackson CL, Gaston SA, Rider CV, Walker VR, Rooney AA. 2023. Systematic evidence mapping informs a class-based approach to assessing personal care products and pubertal timing. Environ Int 181:108307. doi: 10.1016/j.envint.2023.108307. Epub 2023 Nov 4.
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Howdeshell KL, Beverly BEJ, Blain RB, Goldstone AE, Hartman PA, Lemeris CR, Newbold RR, Rooney AA, Bucher JR. 2023. Evaluating endocrine disrupting chemicals: A perspective on the novel assessments in CLARITY-BPA. Birth Defects Res 115(15):1345-1397. doi: 10.1002/bdr2.2238. Epub 2023 Aug 30.
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Abstract
Howdeshell KL, Beverly BEJ, Blain RB, Goldstone AE, Hartman PA, Lemeris CR, Newbold RR, Rooney AA, Bucher JR. 2023. Evaluating endocrine disrupting chemicals: A perspective on the novel assessments in CLARITY-BPA. Birth Defects Res 115(15):1345-1397. doi: 10.1002/bdr2.2238. Epub 2023 Aug 30.
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Howdeshell KL, Hotchkiss AK, Gray LE Jr. 2017. Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment. Int J Hyg Environ Health 220(2 Pt A):179-188. doi: 10.1016/j.ijheh.2016.11.007. Epub 2016 Nov 19.
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Abstract
Howdeshell KL, Hotchkiss AK, Gray LE Jr. 2017. Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment. Int J Hyg Environ Health 220(2 Pt A):179-188. doi: 10.1016/j.ijheh.2016.11.007. Epub 2016 Nov 19.
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Howdeshell KL, Rider CV, Wilson VS, Furr JR, Lambright CR, Gray LE Jr. 2015. Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats. Toxicol Sci 148(2):488-502. doi: 10.1093/toxsci/kfv196. Epub 2015 Sep 8.
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Abstract
Howdeshell KL, Rider CV, Wilson VS, Furr JR, Lambright CR, Gray LE Jr. 2015. Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats. Toxicol Sci 148(2):488-502. doi: 10.1093/toxsci/kfv196. Epub 2015 Sep 8.
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