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Receptor Biology Group
Korach, K.S., Emmen, J.M.A., Walker, V.R., Hewitt, S.C., Yates, M., Hall, J.M., Swope, D.L., Harrell, J.C., Couse, J.F., Update on animal models developed for analyses of estrogen receptor biological activity. J. Steroid Biochem Mol Biol 86: 387-391, 2003 [Abstract Korach, K.S., Emmen, J.M.A., Walker, V.R., Hewitt, S.C., Yates, M., Hall, J.M., Swope, D.L., Harrell, J.C., Couse, J.F., Update on animal models developed for analyses of estrogen receptor biological activity. J. Steroid Biochem Mol Biol 86: 387-391, 2003 ]
Abraham, I.M., Todman, M.G., Korach, K.S., Herbison, A.E., Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in the mouse brain. Endocrinology 145:3055-3061, 2004 [Abstract Abraham, I.M., Todman, M.G., Korach, K.S., Herbison, A.E., Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in the mouse brain. Endocrinology 145:3055-3061, 2004 ]
Grummer, R, Hewitt, S.W., Traub, O., Korach, K.S., Winterhager, E., Different Regulatory Pathways of Endometrial Connexin Expression: Pre-implantation Hormonal Mediated Pathway Versus Embryo Implantation Initiated Pathway. Biol Reprod 71: 273-281, 2004 [Abstract Grummer, R, Hewitt, S.W., Traub, O., Korach, K.S., Winterhager, E., Different Regulatory Pathways of Endometrial Connexin Expression: Pre-implantation Hormonal Mediated Pathway Versus Embryo Implantation Initiated Pathway. Biol Reprod 71: 273-281, 2004 ]
Mueller, S.O., Simon, S., Chae, K., Metzler, M., Korach, K.S., Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor ERα and ER?. Toxicol Sci. 80: 14-25, 2004. [Abstract Mueller, S.O., Simon, S., Chae, K., Metzler, M., Korach, K.S., Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor ERα and ER?. Toxicol Sci. 80: 14-25, 2004. ]
DeRoo, B.J., Hewitt, S.C., Korach, K.S., Estradiol regulates the thioredoxin antioxidant system in the mouse uterus. Endocrinology 145: 5485-5492, 2004. [Abstract DeRoo, B.J., Hewitt, S.C., Korach, K.S., Estradiol regulates the thioredoxin antioxidant system in the mouse uterus. Endocrinology 145: 5485-5492, 2004. ]
Santen, R.J., Yue, W., Boccinfuso, W., Korach, K.S., Wang, J-P., Rogan, E.G., Li, Y., Cavalieri, E., Russo, J., Devanesan, P., Verderame, M., Estradiol-induced carcinogenesis via formation of genotoxic metabolites, In: Advances in endocrine therapy of breast cancer. Ingle, J.N., Dowsett, M. (eds), Marcel Dekker, new York, 163-178, 2004.
Couse, J.F., Korach, K.S., Estrogen receptor-αlpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract. Toxicology 205: 55-63, 2004. [Abstract Couse, J.F., Korach, K.S., Estrogen receptor-αlpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract. Toxicology 205: 55-63, 2004. ]
Walker, V.R., Korach, K.S., Estrogen receptor knockout mice as a model for endocrine research. ILAR Journal 45: 455-461, 2004. [Abstract Walker, V.R., Korach, K.S., Estrogen receptor knockout mice as a model for endocrine research. ILAR Journal 45: 455-461, 2004. ]
Couse, J.F., Yates, M.M., Sanford, R., Nyska, A., Nilson, J.H., Korach, K.S., Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta. Endocrinology 145: 4693-4702, 2004. [Abstract Couse, J.F., Yates, M.M., Sanford, R., Nyska, A., Nilson, J.H., Korach, K.S., Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta. Endocrinology 145: 4693-4702, 2004. ]
Mueller, S.O., Katzenellenbogen, J.A., Korach, K.S., Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids 69: 681-686, 2004. [Abstract Mueller, S.O., Katzenellenbogen, J.A., Korach, K.S., Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids 69: 681-686, 2004. ]
Kavaliers, M., Agmo, A., Choleris, E., Gustafsson, J-A., Korach, K.S., Muglia, L.J., Pfaff, D.W., Ogawa, S., Oxytocin and estrogen receptor alpha and beta knockout mice provide discriminably different odor cues in behavioral assays. Gene Brain Behav. 3: 189-195, 2004. [Abstract Kavaliers, M., Agmo, A., Choleris, E., Gustafsson, J-A., Korach, K.S., Muglia, L.J., Pfaff, D.W., Ogawa, S., Oxytocin and estrogen receptor alpha and beta knockout mice provide discriminably different odor cues in behavioral assays. Gene Brain Behav. 3: 189-195, 2004. ]
Pelzer, T., Loza, P-A.A., Hu, K., Bayer, B., Dienesch, C., Calvillo, L., Korach, K.S., Neyses, L., Ertl, G., Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction. Circulation 111: 1492-1498, 2005. [Abstract Pelzer, T., Loza, P-A.A., Hu, K., Bayer, B., Dienesch, C., Calvillo, L., Korach, K.S., Neyses, L., Ertl, G., Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction. Circulation 111: 1492-1498, 2005. ]
Hewitt, S.C., Collins, J., Grissom, S., Deroo, B., Korach, K.S., Global uterine genomics in vivo: microarray evaluation of the estrogen receptor alpha-growth factor cross-talk mechanism. Mol Endocrinol 19: 657-668, 2005. [Abstract Hewitt, S.C., Collins, J., Grissom, S., Deroo, B., Korach, K.S., Global uterine genomics in vivo: microarray evaluation of the estrogen receptor alpha-growth factor cross-talk mechanism. Mol Endocrinol 19: 657-668, 2005. ]
Skavdahl, M., Steenbergen, C., Clark, J., Myers, P., Demianeko, T., Mao, L., Rockman, H.A., Korach, K.S., Murphy, E., Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy. Am. J. Physiol.: Heart and Circulatory Physiology 288: H469-476, 2005. [Abstract Skavdahl, M., Steenbergen, C., Clark, J., Myers, P., Demianeko, T., Mao, L., Rockman, H.A., Korach, K.S., Murphy, E., Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy. Am. J. Physiol.: Heart and Circulatory Physiology 288: H469-476, 2005. ]
Ardelt, A.A., McCullough, L.D., Korach, K.S., Wang, W.M., Munzenmaier, D.H., Hurn, P.D., Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model. Stroke 36: 337-341, 2005. [Abstract Ardelt, A.A., McCullough, L.D., Korach, K.S., Wang, W.M., Munzenmaier, D.H., Hurn, P.D., Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model. Stroke 36: 337-341, 2005. ]
Gougelet, A., Bouclier,C., Marsaud, V., Maillard, S., Mueller, S.O., Korach, K.S., Renoir, J-M, Estrogen receptor a and b subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells. J. Steroid Biochem Mol Biol 94: 71-81, 2005. [Abstract Gougelet, A., Bouclier,C., Marsaud, V., Maillard, S., Mueller, S.O., Korach, K.S., Renoir, J-M, Estrogen receptor a and b subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells. J. Steroid Biochem Mol Biol 94: 71-81, 2005. ]
Jayachandran, M., Karnicki,K., Miller,R.S., Owen,W.G., Korach,K.S., Miller,V.M., Platelet Characteristics Change with Aging: Role of Estrogen Receptor beta. J Gerontol: Biol Sci. 60: 815-819, 2005. [Abstract Jayachandran, M., Karnicki,K., Miller,R.S., Owen,W.G., Korach,K.S., Miller,V.M., Platelet Characteristics Change with Aging: Role of Estrogen Receptor beta. J Gerontol: Biol Sci. 60: 815-819, 2005. ]
Emmen, J.M.A., Couse, J.F., Elmore, S.A., Yates, M.M., Kissling, G.E., Korach, K.S., In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation. Endocrinology 146: 2817-2826, 2005. [Abstract Emmen, J.M.A., Couse, J.F., Elmore, S.A., Yates, M.M., Kissling, G.E., Korach, K.S., In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation. Endocrinology 146: 2817-2826, 2005. ]
Hewitt, S.C., Deroo, B.J., Korach, K.S., Signal transduction: a new mediator for an old hormone?, Science 307: 1572-1573, 2005. [Abstract Hewitt, S.C., Deroo, B.J., Korach, K.S., Signal transduction: a new mediator for an old hormone?, Science 307: 1572-1573, 2005. ]
Couse, J.F., Yates, M.M., Deroo, B.J., Korach, K.S., Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins. Endocrinology 146: 3247-3262, 2005. [Abstract Couse, J.F., Yates, M.M., Deroo, B.J., Korach, K.S., Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins. Endocrinology 146: 3247-3262, 2005. ]
Aoyama, H., Couse, J.F., Curtis, S.W., Korach, K.S., Haseman, J., Dixon, D. Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane. Tox Appl Pharmacol 209:226-235, 2005. [Abstract Aoyama, H., Couse, J.F., Curtis, S.W., Korach, K.S., Haseman, J., Dixon, D. Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane. Tox Appl Pharmacol 209:226-235, 2005. ]
Tekmal, R.R., Liu, Y.G., Nair, H.B., Jones, J., Perla, R.P., Lubahn, D.B., Korach, K.S., Kirma, N., Estrogen receptor-α is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in aromatase transgenic mice. J. Steroid Biochem Mol Biol 95: 9-15, 2005. [Abstract Tekmal, R.R., Liu, Y.G., Nair, H.B., Jones, J., Perla, R.P., Lubahn, D.B., Korach, K.S., Kirma, N., Estrogen receptor-α is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in aromatase transgenic mice. J. Steroid Biochem Mol Biol 95: 9-15, 2005. ]
Hewitt, S.C., Harrell, J.C., Korach, K.S., Lessons in Estrogen Biology from Knockout and Transgenic Animals, Ann. Rev. Physiol. 67: 285-308, 2005. [Abstract Hewitt, S.C., Harrell, J.C., Korach, K.S., Lessons in Estrogen Biology from Knockout and Transgenic Animals, Ann. Rev. Physiol. 67: 285-308, 2005. ]
Yue, W., Wang, J.P., Li, Y., Bocchinfuso, W.P., Korach, K.S., Devanesan, P.D., Rogan, E., Cavalieri, E., Santen, R. J., Tamoxifen versus aromatase inhibitors for breast cancer prevention. Clin Cancer Res. 11: 925s-930s, 2005. [Abstract Yue, W., Wang, J.P., Li, Y., Bocchinfuso, W.P., Korach, K.S., Devanesan, P.D., Rogan, E., Cavalieri, E., Santen, R. J., Tamoxifen versus aromatase inhibitors for breast cancer prevention. Clin Cancer Res. 11: 925s-930s, 2005. ]
Nomura, M., Andersson, S., Korach, K.S., Gustafsson, J-A, Pfaff, D. W., Ogawa, S., Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behavior in male mice. Neuroscience 23: 1860-1868, 2006. [Abstract Nomura, M., Andersson, S., Korach, K.S., Gustafsson, J-A, Pfaff, D. W., Ogawa, S., Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behavior in male mice. Neuroscience 23: 1860-1868, 2006. ]
LeMay, C., Chu, K., Hu, M., Oretga, C.S., Simpson, E.R., Korach, K.S., Tsai, M-J., Mauvais-Jarvis, F., Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc. Natl. Acad. Sci. 103 : 9232-9237, 2006 . [Abstract LeMay, C., Chu, K., Hu, M., Oretga, C.S., Simpson, E.R., Korach, K.S., Tsai, M-J., Mauvais-Jarvis, F., Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc. Natl. Acad. Sci. 103 : 9232-9237, 2006. ]
Szego, E.M., Barabas, K., Balog, J., Szilagyi, N., Korach, K.S., Juhasz, G., Abraham, I.M., Estrogen induces estrogen receptor alpha dependent CREB phosphorylation via MAPK pathway in basal forebrain cholinergic neurons in vivo . J. Neuroscience 26 : 4104-4110, 2006 . [Abstract Szego, E.M., Barabas, K., Balog, J., Szilagyi, N., Korach, K.S., Juhasz, G., Abraham, I.M., Estrogen induces estrogen receptor alpha dependent CREB phosphorylation via MAPK pathway in basal forebrain cholinergic neurons in vivo. J. Neuroscience 26 : 4104-4110, 2006. ]
Couse, J.F., Yates, M.M., Rodriguez, K.F., Johnson, J.A., Poireir, D., Korach, K.S., The intraovarian actions of estrogen receptor-α (ER-α) are necessary to repress the formation of morphological and functional leydig cells in the female gonad. Endocrinology 147 : 3666-3678, 2006 . [Abstract Couse, J.F., Yates, M.M., Rodriguez, K.F., Johnson, J.A., Poireir, D., Korach, K.S., The intraovarian actions of estrogen receptor-α (ER-α) are necessary to repress the formation of morphological and functional leydig cells in the female gonad. Endocrinology 147 : 3666-3678, 2006. ]
Yamamoto, Y., Moore, R., Hess, H.A., Guo, G.L., Gonzalez, F.J., Korach, K.S., Maronpot, R.R., Negishi, M., Estrogen receptor alpha mediates 17alpha-ethynylestradiol-causing hepatotoxicity. J. Biol. Chem. 281 : 16625-16631, 2006 . [Abstract Yamamoto, Y., Moore, R., Hess, H.A., Guo, G.L., Gonzalez, F.J., Korach, K.S., Maronpot, R.R., Negishi, M., Estrogen receptor alpha mediates 17alpha-ethynylestradiol-causing hepatotoxicity. J. Biol. Chem. 281 : 16625-16631, 2006. ]
Qiu, J., Bosch, M.A., Tobias, S.C., Krust, A., Graham, S.M., Murphy, S.J., Korach, K.S., Chambon, P., Scanlan, T.S., Ronnekleiv, O.K., Kelly, M.J., A G protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. J. Neuroscience 26 : 5649-5655, 2006 . [Abstract Qiu, J., Bosch, M.A., Tobias, S.C., Krust, A., Graham, S.M., Murphy, S.J., Korach, K.S., Chambon, P., Scanlan, T.S., Ronnekleiv, O.K., Kelly, M.J., A G protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. J. Neuroscience 26 : 5649-5655, 2006. ]
Lindzey, J., Jayes, F.L., Yates, M.M., Couse, J.F., Korach, K.S., The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-α (ER-α). J. Endocrinology 191 : 309-317, 2006 [Abstract Lindzey, J., Jayes, F.L., Yates, M.M., Couse, J.F., Korach, K.S., The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-α (ER-α). J. Endocrinology 191 : 309-317, 2006 ]
Choleris, E., Ogawa, S., Kavaliers, M.,Gustafsson, J.-Å, Korach, K.S., Muglia, L. J., Pfaff, D.W., Involvement of estrogen receptor alpha, beta and oxytocin in social discrimination: A detailed behavioral analysis with knockout female mice. Genes Brain Behav. 5 :528-539, 2006 . [Abstract Choleris, E., Ogawa, S., Kavaliers, M.,Gustafsson, J.-Å, Korach, K.S., Muglia, L. J., Pfaff, D.W., Involvement of estrogen receptor alpha, beta and oxytocin in social discrimination: A detailed behavioral analysis with knockout female mice. Genes Brain Behav. 5 :528-539, 2006. ]
O’Brien, J.E., Peterson, T.J., Tong, M.H., Lee, E-J., Pfaff, L.E., Hewitt, S.C., Korach, K.S., Weiss, J., Jameson, J.L., Estrogen induced proliferation of uterine epithelial cells is independent of estrogen receptor a binding to classical estrogen response elements . J. Biol. Chem. 281: 26683-26692, 2006 . [Abstract O’Brien, J.E., Peterson, T.J., Tong, M.H., Lee, E-J., Pfaff, L.E., Hewitt, S.C., Korach, K.S., Weiss, J., Jameson, J.L., Estrogen induced proliferation of uterine epithelial cells is independent of estrogen receptor a binding to classical estrogen response elements. J. Biol. Chem. 281: 26683-26692, 2006. ]
Dahlman-Wright, K., Cavailles, V., Fuqua, S.A., Jordan, V.C., Katzenellenbogen, J.A., Korach, K.S., Maggi, A., Muramatsu, M., Parker, M.G., Gustafsson, J.A., International union of pharmacology. LXIV. Estrogen Receptors . Pharmacol Rev. 58 : 773-781, 2006 . [Abstract Dahlman-Wright, K., Cavailles, V., Fuqua, S.A., Jordan, V.C., Katzenellenbogen, J.A., Korach, K.S., Maggi, A., Muramatsu, M., Parker, M.G., Gustafsson, J.A., International union of pharmacology. LXIV. Estrogen Receptors. Pharmacol Rev. 58 : 773-781, 2006. ]
Henley, D.V., Korach, K.S., Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function. Endocrinology 147: 25s-32s, 2006. [Abstract Henley, D.V., Korach, K.S., Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function. Endocrinology 147: 25s-32s, 2006. ]
Couse, J.F., Hewitt, S.C., Korach, K.S., Steroid Receptors in the Ovary and Uterus , In: Knobil and Neill: Physiology of Reproduction 3rd Edition, Neill, J.D. (ed.), Academic Press, New York, New York, p 593-678, 2006.
Lindzey, J., Korach, K.S., Environmental agents and the reproductive system, In: DeGroot, L.J. Jameson, L.J. (eds.), Endocrinology, W.B. Saunders, Co., New York, New York, pp 2759-2777, 2006 .
Taniguchi, F., Couse, J.F., Rodriguez, K.F., Poirier, D., Korach, K.S., Estrogen receptor-α (ERa) mediates an intraovarian negative feedback loop on thecal cell androgen synthesis via modulation of Cyp17a1 expression. FASEB J. 21 : 586-595, 2007. [Abstract Taniguchi, F., Couse, J.F., Rodriguez, K.F., Poirier, D., Korach, K.S., Estrogen receptor-α (ERa) mediates an intraovarian negative feedback loop on thecal cell androgen synthesis via modulation of Cyp17a1 expression. FASEB J. 21 : 586-595, 2007. ]
Henley, D.V., Lipson, N., Korach, K.S., Bloch, C.A., Prepubertal gynecomastia and lavender and tea tree oils . New Eng. J. Med. 356: 479-485, 2007 . [Abstract Henley, D.V., Lipson, N., Korach, K.S., Bloch, C.A., Prepubertal gynecomastia and lavender and tea tree oils. New Eng. J. Med. 356: 479-485, 2007. ]
Carey, M.A., Card, J.W., Bradbury, J.A., Moorman, M.P., Haykal-Coates, N., Gavett, S.H., Graves,J.P., Walker,V.R., Flake,G.P., Voltz, J.W., Zhu, D., Jacobs ,E.R., Dakhama, A., Larsen, G.L., Loader, J.L., Gelfand, E.W., Germolec, D.R., Korach, K.S., Zeldin,D.C., Spontaneous airway hyperresponsiveness in estrogen receptor-α deficient mice. Am J. Respiratory and Critical Care Medicine 175 : 126-135, 2007 . [Abstract Carey, M.A., Card, J.W., Bradbury, J.A., Moorman, M.P., Haykal-Coates, N., Gavett, S.H., Graves,J.P., Walker,V.R., Flake,G.P., Voltz, J.W., Zhu, D., Jacobs ,E.R., Dakhama, A., Larsen, G.L., Loader, J.L., Gelfand, E.W., Germolec, D.R., Korach, K.S., Zeldin,D.C., Spontaneous airway hyperresponsiveness in estrogen receptor-α deficient mice. Am J. Respiratory and Critical Care Medicine 175 : 126-135, 2007. ]
Hewitt, S.C., O'Brien, J., Jameson, L., Kissling, G., Korach, K.S. Selective disruption of ER{alpha} DNA-binding activity alters uterine responsiveness to estradiol . Molecular endocrinology (Baltimore, Md.) 23(12):2111-2116, 2009 . [Abstract Hewitt, S.C., O'Brien, J., Jameson, L., Kissling, G., Korach, K.S. Selective disruption of ER{alpha} DNA-binding activity alters uterine responsiveness to estradiol. Molecular endocrinology (Baltimore, Md.) 23(12):2111-2116, 2009. ]
Winuthayanon, W., Piyachaturawat, P., Suksamrarn, A., Ponglikitmongkol, M., Arao, Y., Hewitt, S.C., Korach, K.S. Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: Biological actions in vivo and in vitro indicate ER-dependent mechanisms . Environmental health perspectives 117(7):1155-1161, 2009 . [Abstract Winuthayanon, W., Piyachaturawat, P., Suksamrarn, A., Ponglikitmongkol, M., Arao, Y., Hewitt, S.C., Korach, K.S. Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: Biological actions in vivo and in vitro indicate ER-dependent mechanisms. Environmental health perspectives 117(7):1155-1161, 2009. ]
Deroo, B.J., Couse, J.F., Hamilton, K.J., Rodriguez, K.F., Collins, J.B., Grissom, S.F., Korach, K.S. Estrogen receptor beta is required for optimal cAMP production in mouse granulosa cells . Molecular endocrinology (Baltimore, Md.) 23(7):955-965, 2009 . [Abstract Deroo, B.J., Couse, J.F., Hamilton, K.J., Rodriguez, K.F., Collins, J.B., Grissom, S.F., Korach, K.S. Estrogen receptor beta is required for optimal cAMP production in mouse granulosa cells. Molecular endocrinology (Baltimore, Md.) 23(7):955-965, 2009. ]
Hewitt, S.C., Li, Y., Li, L., Korach, K.S. Estrogen Regulation of Igf1 and Uterine Growth Involves Direct Binding of Estrogen Receptors to Estrogen Responsive Elements . Journal of Biological Chemistry 285(4):2676-2685, 2010 . [Abstract Hewitt, S.C., Li, Y., Li, L., Korach, K.S. Estrogen Regulation of Igf1 and Uterine Growth Involves Direct Binding of Estrogen Receptors to Estrogen Responsive Elements. Journal of Biological Chemistry 285(4):2676-2685, 2010. ]
Bernardo, G.M., Lozada, K.L., Miedler, J.D., Harburg, G., Hewitt, S.C., Mosley, J.D., Godwin, A.K., Korach, K.S., Visvader, J.E., Kaestner, K.H., Abdul-Karim, F.W., Montano, M.M., Keri, R.A. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis . Development (Cambridge, England) 137(12):2045-2054, 2010 . [Abstract Bernardo, G.M., Lozada, K.L., Miedler, J.D., Harburg, G., Hewitt, S.C., Mosley, J.D., Godwin, A.K., Korach, K.S., Visvader, J.E., Kaestner, K.H., Abdul-Karim, F.W., Montano, M.M., Keri, R.A. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (Cambridge, England) 137(12):2045-2054, 2010. ]
Hewitt, S.C., Kissling, G.E., Fieselman, K.E., Jayes, F.L., Gerrish, K.E., Korach, K.S. Biological and biochemical consequences of global deletion of exon 3 from the ER{alpha} gene . The FASEB journal 24(12):4660-4667, 2010 . [Abstract Hewitt, S.C., Kissling, G.E., Fieselman, K.E., Jayes, F.L., Gerrish, K.E., Korach, K.S. Biological and biochemical consequences of global deletion of exon 3 from the ER{alpha} gene. The FASEB journal 24(12):4660-4667, 2010. ]
Arao Y, Carpenter K, Hewitt S, Korach KS. Estrogen down-regulation of the Scx gene is mediated by the opposing strand-overlapping gene Bop1. The Journal of biological chemistry 285(7):4806-4814, 2010. [Abstract Arao Y, Carpenter K, Hewitt S, Korach KS. Estrogen down-regulation of the Scx gene is mediated by the opposing strand-overlapping gene Bop1. The Journal of biological chemistry 285(7):4806-4814, 2010. ]
Arao Y, Hamilton KJ , Ray MK, Scott GJ, Mishina Y, Korach K. Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proceedings of the National Academy of Sciences of the United States of America, 108(36):14986-14991, 2011. [Abstract Arao Y, Hamilton KJ , Ray MK, Scott GJ, Mishina Y, Korach K. Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proceedings of the National Academy of Sciences of the United States of America, 108(36):14986-14991, 2011. ]
Winuthayanon, W., Hewitt, S.C., Orvis, G.D., Behringer, R.R., Korach, K.S. Uterine Epithelial Estrogen Receptor alpha is Dispensable for Proliferation But Essential for Complete Biological and Biochemical Responses . Proceedings of the National Academy of Sciences of the United States of America 107(45):19272-19277, 2010 . [Abstract Winuthayanon, W., Hewitt, S.C., Orvis, G.D., Behringer, R.R., Korach, K.S. Uterine Epithelial Estrogen Receptor alpha is Dispensable for Proliferation But Essential for Complete Biological and Biochemical Responses. Proceedings of the National Academy of Sciences of the United States of America 107(45):19272-19277, 2010. ]
Hewitt, S.C., Korach, K.S. Estrogenic Activity of Bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) Demonstrated in Mouse Uterine Gene Profiles . Environmental health perspectives 119(1):63-70, 2011 . [Abstract Hewitt, S.C., Korach, K.S. Estrogenic Activity of Bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) Demonstrated in Mouse Uterine Gene Profiles. Environmental health perspectives 119(1):63-70, 2011. ]
Ribas, V., Drew, B.G., Le, J.A., Soleymani, T., Daraei, P., Sitz, D., Mohammad, L., Henstridge, D.C., Febbraio, M.A., Hewitt, S.C., Korach, K.S., Bensinger, S..J, Hevener, A.L. Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development . Proceedings of the National Academy of Sciences of the United States of America 108(39):16457-16462, 2011 . [Abstract Ribas, V., Drew, B.G., Le, J.A., Soleymani, T., Daraei, P., Sitz, D., Mohammad, L., Henstridge, D.C., Febbraio, M.A., Hewitt, S.C., Korach, K.S., Bensinger, S..J, Hevener, A.L. Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development. Proceedings of the National Academy of Sciences of the United States of America 108(39):16457-16462, 2011. ]
Burns KA, Li Y, Arao Y, Petrovich RM, Korach KS. Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms. The Journal of biological chemistry 286(14):12640-12649, 2011. [Abstract Burns KA, Li Y, Arao Y, Petrovich RM, Korach KS. Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms. The Journal of biological chemistry 286(14):12640-12649, 2011. ]
Hewitt, S.C., Korach, K.S. A hand to support the implantation window . Science 331(6019):683-684, 2011 . [Abstract Hewitt, S.C., Korach, K.S. A hand to support the implantation window. Science 331(6019):683-684, 2011. ]
Stewart, A.C., Fisher, S.J., Wang, Y., Stewart, M.D., Hewitt, S.C., Rodriguez, K.F., Korach, K.S., Behringer, R.R. Uterine gland formation in mice is a continuous process, requiring the ovary after puberty, but not after parturition . Biology of Reproduction 2011 85(5):954-964. [Abstract Stewart, A.C., Fisher, S.J., Wang, Y., Stewart, M.D., Hewitt, S.C., Rodriguez, K.F., Korach, K.S., Behringer, R.R. Uterine gland formation in mice is a continuous process, requiring the ovary after puberty, but not after parturition. Biology of Reproduction 2011 85(5):954-964. ]
Hart-Unger S, Korach KS. Estrogens and obesity: is it all in our heads? Cell metabolism 14(4):435-6, 2011. [Abstract Hart-Unger S, Korach KS. Estrogens and obesity: is it all in our heads? Cell metabolism 14(4):435-6, 2011. ]
Li Y., Burns K.A., Arao Y., Luh C.J., Korach K.S. Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro . Environmental health perspectives 120(7):1029-1035, 2012. [Abstract Li Y., Burns K.A., Arao Y., Luh C.J., Korach K.S. Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro. Environmental health perspectives 120(7):1029-1035, 2012. ]
Burns K.A., Rodriguez K.F., Hewitt S.C., Janardhan K.S., Young S.L., Korach K.S. Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model. Endocrinology 153(8):3960-3971, 2012 . [Abstract Burns K.A., Rodriguez K.F., Hewitt S.C., Janardhan K.S., Young S.L., Korach K.S. Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model. Endocrinology 153(8):3960-3971, 2012. ]
Arao Y., Hamilton K.J., Goulding E.H., Janardhan K.S., Eddy E.M., Korach K.S. Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function. Proceedings of the National Academy of Sciences of the United States of America 109(51):21140-21145, 2012. [Abstract Arao Y., Hamilton K.J., Goulding E.H., Janardhan K.S., Eddy E.M., Korach K.S. Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function. Proceedings of the National Academy of Sciences of the United States of America 109(51):21140-21145, 2012. ]
Davis VL, Newbold RR, Couse JF, Rea SL, Gallagher KM, Hamilton KJ, Goulding EH, Jefferson W, Eddy EM, Bullock BC, Korach KS. Expression of a dominant negative estrogen receptor alpha variant in transgenic mice accelerates uterine cancer induced by the potent estrogen diethylstilbestrol . Reproductive toxicology (Elmsford, N.Y.) 34(4):512-521, 2012 [Abstract Davis VL, Newbold RR, Couse JF, Rea SL, Gallagher KM, Hamilton KJ, Goulding EH, Jefferson W, Eddy EM, Bullock BC, Korach KS. Expression of a dominant negative estrogen receptor alpha variant in transgenic mice accelerates uterine cancer induced by the potent estrogen diethylstilbestrol. Reproductive toxicology (Elmsford, N.Y.) 34(4):512-521, 2012 ]
Burns K.A., Korach K.S., Estrogen receptors and human disease: an update . Archives of toxicology 86(10):1491-1504, 2012 . [Abstract Burns K.A., Korach K.S., Estrogen receptors and human disease: an update. Archives of toxicology 86(10):1491-1504, 2012. ]
Li Y, Luh CJ, Burn KA, Arao Y, Jiang Z, Teng CT, Tice EE, Korach KS. Endocrine-disrupting chemicals (EDCs): in vitro mechanism of estrogenic activation and differential effects on ER target genes. Environ Health Perspect 2013; 121(4): 459-466. [Abstract Li Y, Luh CJ, Burn KA, Arao Y, Jiang Z, Teng CT, Tice EE, Korach KS. Endocrine-disrupting chemicals (EDCs): in vitro mechanism of estrogenic activation and differential effects on ER target genes. Environ Health Perspect 2013; 121(4): 459-466. ]
Wall EH, Hewitt SC, Liu L, del Rio R, Case LK, Lin CY, Korach KS, Teuscher C. Genetic control of estrogen-regulated transcriptional and cellular responses in mouse uterus . FASEB journal: official publication of the Federation of American Societies for Experimental Biology 27(5):1874-1886, 2013 . [Abstract Wall EH, Hewitt SC, Liu L, del Rio R, Case LK, Lin CY, Korach KS, Teuscher C. Genetic control of estrogen-regulated transcriptional and cellular responses in mouse uterus. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 27(5):1874-1886, 2013. ]
Binder AK, Rodriguez KF, Hamilton KJ, Stockton PS, Reed CE, Korach KS. The Absence of ERβ Results in Altered Gene Expression in Ovarian Granulosa Cells Isolate From In Vivo Preovulatory Follicles. Endocrinology, June 2013, 154(6):2174 [Abstract Binder AK, Rodriguez KF, Hamilton KJ, Stockton PS, Reed CE, Korach KS. The Absence of ERβ Results in Altered Gene Expression in Ovarian Granulosa Cells Isolate From In Vivo Preovulatory Follicles. Endocrinology, June 2013, 154(6):2174 ]
Arao Y., Hamilton K.J., Coons L.A., Korach K.S. Estrogen Receptor α L543A,L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity . The Journal of biological chemistry 288(29):21105-21116, 2013. [Abstract Arao Y., Hamilton K.J., Coons L.A., Korach K.S. Estrogen Receptor α L543A,L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity. The Journal of biological chemistry 288(29):21105-21116, 2013. ]
Winuthayanon W, Piyachaturawat P, Suksamrarn A, Burns KA, Arao Y, Hewitt SC, Pedersen LC, Korach KS. The natural estrogenic compound diarylheptanoid (D3): in vitro mechanisms of action and in vivo uterine responses via estrogen receptor α . Environmental health perspectives 121(4):433-439, 2013. [Abstract Winuthayanon W, Piyachaturawat P, Suksamrarn A, Burns KA, Arao Y, Hewitt SC, Pedersen LC, Korach KS. The natural estrogenic compound diarylheptanoid (D3): in vitro mechanisms of action and in vivo uterine responses via estrogen receptor α. Environmental health perspectives 121(4):433-439, 2013. ]
Arao Y, Hamilton KJ, Korach KS. The Transactivating Function 2 (AF-2) of Estrogen Receptor (ER) α Is Indispensable for ERα-Mediated Physiological Responses and AF-1 Activity. Open Journal of Endocrine and Metabolic Diseases 3(4B):12-19, 2013. [Abstract Arao Y, Hamilton KJ, Korach KS. The Transactivating Function 2 (AF-2) of Estrogen Receptor (ER) α Is Indispensable for ERα-Mediated Physiological Responses and AF-1 Activity. Open Journal of Endocrine and Metabolic Diseases 3(4B):12-19, 2013. ]
Burns KA, Zorrilla LM, Hamilton KJ, Reed CE, Birnbaum LS, Korach KS. A Single Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Disrupts the Adult Uterine Response to Estradiol in Mice. Toxicological Sciences 2013 136(2):514-526. [Abstract Burns KA, Zorrilla LM, Hamilton KJ, Reed CE, Birnbaum LS, Korach KS. A Single Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Disrupts the Adult Uterine Response to Estradiol in Mice. Toxicological Sciences 2013 136(2):514-526. ]
Jayes FL, Burns KA, Rodriguez KF, Kissling GE, Korach KS. The naturally occurring luteinizing hormone surge is diminished in mice lacking estrogen receptor Beta in the ovary. Biology of reproduction 2014 90(2):24-. [Abstract Jayes FL, Burns KA, Rodriguez KF, Kissling GE, Korach KS. The naturally occurring luteinizing hormone surge is diminished in mice lacking estrogen receptor Beta in the ovary. Biology of reproduction 2014 90(2):24-. ]
Li Y, Hamiltom KJ, Lai AY, Burns KA, Li L, Wade PA, Korach KS. Diethylstilbestrol (DES)-stimulated hormonal toxicity is mediated by ERalpha alteration of target gene methylation patterns and epigenetic modifiers (DNMT3A, MBD2, and HDAC2) in the mouse seminal vesicle. Environmental health perspectives 2014 122(3):262-268. [Abstract Li Y, Hamiltom KJ, Lai AY, Burns KA, Li L, Wade PA, Korach KS. Diethylstilbestrol (DES)-stimulated hormonal toxicity is mediated by ERalpha alteration of target gene methylation patterns and epigenetic modifiers (DNMT3A, MBD2, and HDAC2) in the mouse seminal vesicle. Environmental health perspectives 2014 122(3):262-268. ]
Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, DeMayo FJ, Schütz G, Korach KS. Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse. Molecular endocrinology (Baltimore, Md.) 2014 28(6):899-911. [Abstract Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, DeMayo FJ, Schütz G, Korach KS. Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse. Molecular endocrinology (Baltimore, Md.) 2014 28(6):899-911. ]
Wall EH, Hewitt SC, Case LK, Lin CY, Korach KS, Teuscher C. The role of genetics in estrogen responses: a critical piece of an intricate puzzle. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 2014 28(12):5042-5054 . [Abstract Wall EH, Hewitt SC, Case LK, Lin CY, Korach KS, Teuscher C. The role of genetics in estrogen responses: a critical piece of an intricate puzzle. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 2014 28(12):5042-5054. ]
Winuthayanon W, Hewitt SC, Korach KS. Uterine epithelial cell estrogen receptor alpha-dependent and -independent genomic profiles that underlie estrogen responses in mice. Biology of reproduction 2014 91(5):110- . [Abstract Winuthayanon W, Hewitt SC, Korach KS. Uterine epithelial cell estrogen receptor alpha-dependent and -independent genomic profiles that underlie estrogen responses in mice. Biology of reproduction 2014 91(5):110-. ]
Hamilton KJ, Arao Y, Korach KS. Estrogen hormone physiology: reproductive findings from estrogen receptor mutant mice. Reproductive biology 2014 14(1):3-8. [Abstract Hamilton KJ, Arao Y, Korach KS. Estrogen hormone physiology: reproductive findings from estrogen receptor mutant mice. Reproductive biology 2014 14(1):3-8. ]
Li Y, Arao Y, Hall JM, Burkett S, Liu L, Gerrish K, Cavailles V, Korach K. Research Resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant . Molecular endocrinology (Baltimore, Md.) 2014 28(12):2072-2081. [Abstract Li Y, Arao Y, Hall JM, Burkett S, Liu L, Gerrish K, Cavailles V, Korach K. Research Resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant. Molecular endocrinology (Baltimore, Md.) 2014 28(12):2072-2081. ]
Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Foley JF, Flagler N, Ney E, Suksamrarn A, Piyachaturawat P, Bushel PR, Korach KS. Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice. Environmental health perspectives 2015 123(4):344-352. [Abstract Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Foley JF, Flagler N, Ney E, Suksamrarn A, Piyachaturawat P, Bushel PR, Korach KS. Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice. Environmental health perspectives 2015 123(4):344-352. ]
Arao Y, Coons LA, Zuercher WJ, Korach KS. Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element . The Journal of biological chemistry 2015 290(28):17611-17627. [Abstract Arao Y, Coons LA, Zuercher WJ, Korach KS. Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element. The Journal of biological chemistry 2015 290(28):17611-17627. ]
Winuthayanon W, Hewitt SC, Padilla-Banks E, Myers PH, Orvis GD, Behringer RR, Korach KS, Williams CJ. Oviductal estrogen receptor α signaling prevents protease-mediated embryo death . eLife ():- , 2015 4:e10453. [Abstract Winuthayanon W, Hewitt SC, Padilla-Banks E, Myers PH, Orvis GD, Behringer RR, Korach KS, Williams CJ. Oviductal estrogen receptor α signaling prevents protease-mediated embryo death. eLife ():-, 2015 4:e10453. ]
Donoghue LJ, Neufeld TI, Li Y, Arao Y, Coons LA, Korach KS. Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs). Environmental health perspectives 2016 125(4):634-642. [Abstract Donoghue LJ, Neufeld TI, Li Y, Arao Y, Coons LA, Korach KS. Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs). Environmental health perspectives 2016 125(4):634-642. ]
Yip KY, Wan ML, Wong AS, Korach KS, El-Nezami H. Combined low-dose zearalenone and aflatoxin B1 on cell growth and cell-cycle progression in breast cancer MCF-7 cells . Toxicology Letters 2017 281:139-151. [Abstract Yip KY, Wan ML, Wong AS, Korach KS, El-Nezami H. Combined low-dose zearalenone and aflatoxin B1 on cell growth and cell-cycle progression in breast cancer MCF-7 cells. Toxicology Letters 2017 281:139-151. ]
Stefkovich ML, Arao Y, Hamilton KJ, Korach KS. Experimental Models for Evaluating Non-Genomic Estrogen Signaling. Steroids 2018 133:34-37. [Abstract Stefkovich ML, Arao Y, Hamilton KJ, Korach KS. Experimental Models for Evaluating Non-Genomic Estrogen Signaling. Steroids 2018 133:34-37. ]
Li Y, Hamilton KJ, Wang T, Coons LA, Wang Y, Jefferson WN, Li R, Grimm SA, Ramsey JT, Liu L, Gerrish KE, Wiliams CJ, Wade PA, Korach KS. DNA Methylation and Transcriptome Aberrations Mediated by ERα in Mouse Seminal Vesicles Following Developmental DES Exposure. Proceedings of the National Academy of Sciences of the United States of America 2018 115(18):E4189-E4198. [Abstract Li Y, Hamilton KJ, Wang T, Coons LA, Wang Y, Jefferson WN, Li R, Grimm SA, Ramsey JT, Liu L, Gerrish KE, Wiliams CJ, Wade PA, Korach KS. DNA Methylation and Transcriptome Aberrations Mediated by ERα in Mouse Seminal Vesicles Following Developmental DES Exposure. Proceedings of the National Academy of Sciences of the United States of America 2018 115(18):E4189-E4198. ]
Arao Y, Korach KS. Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay. Journal of visualized experiments: JoVE 2018 (142):-. [Abstract Arao Y, Korach KS. Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay. Journal of visualized experiments: JoVE 2018 (142):-. ]
Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, DeMayo FJ, Korach KS. A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Insulin-like growth factor 1 (Igf1) . The Journal of biological chemistry 2019 294(25):9746-9759. [Abstract Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, DeMayo FJ, Korach KS. A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Insulin-like growth factor 1 (Igf1). The Journal of biological chemistry 2019 294(25):9746-9759. ]
Arao Y, Hamilton KJ, Wu SP, Tsai MJ, DeMayo FJ, Korach KS. Dysregulation of Hypothalamic-pituitary Estrogen Receptor α-mediated Signaling Causes Episodic LH Secretion and Cystic Ovary. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 2019 33(6):7375-7386. [Abstract Arao Y, Hamilton KJ, Wu SP, Tsai MJ, DeMayo FJ, Korach KS. Dysregulation of Hypothalamic-pituitary Estrogen Receptor α-mediated Signaling Causes Episodic LH Secretion and Cystic Ovary. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 2019 33(6):7375-7386. ]
Ramsey JT, Li Y, Arao Y, Coons LA, Korach KS. Lavender Products Associated with Premature Thelarche and Prepubertal Gynecomastia: Case Reports and EDC Activities . The Journal of Clinical Endocrinology and Metabolism 2019 doi: 10.1210/jc.2018-01880 [Online 8 August 2019]. [Abstract Ramsey JT, Li Y, Arao Y, Coons LA, Korach KS. Lavender Products Associated with Premature Thelarche and Prepubertal Gynecomastia: Case Reports and EDC Activities. The Journal of Clinical Endocrinology and Metabolism 2019 doi: 10.1210/jc.2018-01880 [Online 8 August 2019]. ]
Pelch KE, Li Y, Perera L, Thayer KA, Korach KS. 2019. Characterization of Estrogenic and Androgenic Activities for Bisphenol A-like Chemicals (BPs): In Vitro Estrogen and Androgen Receptors Transcriptional Activation, Gene Regulation, and Binding Profiles . Toxicological Sciences ; doi: 10.1093/toxsci/kfz173 [Online 6 August 2019]. [Abstract Pelch KE, Li Y, Perera L, Thayer KA, Korach KS. 2019. Characterization of Estrogenic and Androgenic Activities for Bisphenol A-like Chemicals (BPs): In Vitro Estrogen and Androgen Receptors Transcriptional Activation, Gene Regulation, and Binding Profiles. Toxicological Sciences; doi: 10.1093/toxsci/kfz173 [Online 6 August 2019]. ]
Arao Y, Korach KS. 2019. Transactivation Function-1-Mediated Partial Agonist Activity of Selective Estrogen Receptor Modulator Requires Homo-Dimerization of the Estrogen Receptor α Ligand Binding Domain. Int J Mol Sci ; doi: 10.3390/ijms20153718 [Online 30 July 2019]. [Abstract Arao Y, Korach KS. 2019. Transactivation Function-1-Mediated Partial Agonist Activity of Selective Estrogen Receptor Modulator Requires Homo-Dimerization of the Estrogen Receptor α Ligand Binding Domain. Int J Mol Sci; doi: 10.3390/ijms20153718 [Online 30 July 2019]. ]
Li Y, Hamilton KJ, Perera L, Wang T, Gruzdev A, Jefferson TB, Zhang AX, Mathura E, Gerrish KE, Wharey L, Martin NP, Li J, Korach KS. 2020. ESR1 Mutations Associated With EIS Change Conformation of Ligand Receptor Complex and Alter Transcriptome Profile . Endocrinology ; doi: 10.1210/endocr/bqaa050 [Online 1 June 2020]. [Abstract Li Y, Hamilton KJ, Perera L, Wang T, Gruzdev A, Jefferson TB, Zhang AX, Mathura E, Gerrish KE, Wharey L, Martin NP, Li J, Korach KS. 2020. ESR1 Mutations Associated With EIS Change Conformation of Ligand Receptor Complex and Alter Transcriptome Profile. Endocrinology; doi: 10.1210/endocr/bqaa050 [Online 1 June 2020]. ]
Herrera GGB, Lierz SL, Harris EA, Donoghue LJ, Hewitt SC, Rodriguez KF, Jefferson WN, Lydon JP, DeMayo FJ, Williams CJ, Korach KS, Winuthayanon W. 2020. Oviductal retention of embryos in female mice lacking estrogen receptor α in the isthmus and the uterus . Endocrinology ; doi: 10.1210/endocr/bqz033 [Online 1 February 2020]. [Abstract Herrera GGB, Lierz SL, Harris EA, Donoghue LJ, Hewitt SC, Rodriguez KF, Jefferson WN, Lydon JP, DeMayo FJ, Williams CJ, Korach KS, Winuthayanon W. 2020. Oviductal retention of embryos in female mice lacking estrogen receptor α in the isthmus and the uterus. Endocrinology; doi: 10.1210/endocr/bqz033 [Online 1 February 2020]. ]
Hewitt SC, Grimm SA, Wu SP, DeMayo FJ, Korach KS. 2020. Estrogen receptor α (ERα)-binding super enhancers drive key mediators that control uterine estrogen responses in mice . J Biol Chem ; doi: 10.1074/jbc.RA120.013666 [Online 30 April 2020]. [Abstract Hewitt SC, Grimm SA, Wu SP, DeMayo FJ, Korach KS. 2020. Estrogen receptor α (ERα)-binding super enhancers drive key mediators that control uterine estrogen responses in mice. J Biol Chem; doi: 10.1074/jbc.RA120.013666 [Online 30 April 2020]. ]
Ramsey JT, Shropshire BC, Nagy TR, Chambers KD, Li Y, Korach KS. 2020. Essential Oils and Health . Yale J Biol Med 93(2):291-305. [Abstract Ramsey JT, Shropshire BC, Nagy TR, Chambers KD, Li Y, Korach KS. 2020. Essential Oils and Health. Yale J Biol Med 93(2):291-305. ]
Hewitt SC, Carmona M, Foley KG, Donoghue LJ, Lierz SL, Winuthayanon W, Korach KS. 2020. Peri- and Postpubertal Estrogen Exposures of Female Mice Optimize Uterine Responses Later in Life . Endocrinology ; doi: 10.1210/endocr/bqaa081 [Online 1 August 2020]. [Abstract Hewitt SC, Carmona M, Foley KG, Donoghue LJ, Lierz SL, Winuthayanon W, Korach KS. 2020. Peri- and Postpubertal Estrogen Exposures of Female Mice Optimize Uterine Responses Later in Life. Endocrinology; doi: 10.1210/endocr/bqaa081 [Online 1 August 2020]. ]
Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. 2020. Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling . Sci Transl Med ; doi: 10.1126/scitranslmed.aax8096 [Online 5 August 2020]. [Abstract Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. 2020. Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling. Sci Transl Med; doi: 10.1126/scitranslmed.aax8096 [Online 5 August 2020]. ]
Li Y, Coons LA, Houtman R, Carlson KE, Martin TA, Mayne CG, Melchers D, Jefferson TB, Ramsey JT, Katzenellenbogen JA, Korach KS. 2020. A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment . Sci Signal ; doi: 10.1126/scisignal.aaw4653 [Online 22 September 2020]. [Abstract Li Y, Coons LA, Houtman R, Carlson KE, Martin TA, Mayne CG, Melchers D, Jefferson TB, Ramsey JT, Katzenellenbogen JA, Korach KS. 2020. A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment. Sci Signal; doi: 10.1126/scisignal.aaw4653 [Online 22 September 2020]. ]
Arao Y, Hamilton KJ, Grimm SA, Korach KS. 2020. The genomic regulatory elements for estrogen receptor alpha transactivation-function-1 regulated genes . FASEB J ; doi: 10.1096/fj.202001435R [Online 16 October 2020]. [Abstract Arao Y, Hamilton KJ, Grimm SA, Korach KS. 2020. The genomic regulatory elements for estrogen receptor alpha transactivation-function-1 regulated genes. FASEB J; doi: 10.1096/fj.202001435R [Online 16 October 2020]. ]
Arao Y, Korach KS. 2021. The physiological role of estrogen receptor functional domains . Essays Biochem EBC20200167. [Abstract Arao Y, Korach KS. 2021. The physiological role of estrogen receptor functional domains. Essays Biochem EBC20200167. ]
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Last Reviewed: June 25, 2021