
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
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Michelle C. Cora, D.V.M., D.A.C.V.P.
Group Leader, Clinical Pathology -
Tel 984-287-3828
[email protected] -
111 TW ALEXANDER DRDavid P Rall BuildingResearch Triangle Park, NC 27709
Research Summary
Michelle Cora, D.V.M., D.A.C.V.P., leads the Clinical Pathology Group within the Comparative and Molecular Pathogenesis Branch (CMPB). She is also the principal clinical pathologist for the Division of Translational Toxicology (DTT), providing clinical pathology oversight and preparation for various National Toxicology Program (NTP) and NIEHS studies. As a veterinary clinical pathologist, Cora has expertise in clinical laboratory methods, and the diagnosis of diseases and toxicologic effects as observed with the use of hematology, clinical chemistry, urinalysis and cytology (including rodent vaginal cytology) methods. She has co-authored numerous publications, including over 40 NTP toxicology and technical reports regarding compounds studied by the NTP. She has also co-chaired several Society of Toxicologic Pathology committees, as well as served on the editorial board for the journal of Toxicologic Pathology.
Cora received her Doctor of Veterinary Medicine (DVM) from University of Illinois in 2000, after which she practiced small animal medicine for 7 years in the Seattle area. After those years of clinical practice, she came to Raleigh for residency training in veterinary clinical pathology at North Carolina State University, College of Veterinary Medicine (NCSU-CVM). After her residency training, Cora completed a DTT toxicological clinical pathology research fellowship and subsequently joined the staff of CMPB. Some of her research interests include the mechanisms by which black cohosh extract causes a megaloblastic anemia in mice and rats, and how metabolomic and proteomic data can further inform and build upon clinical pathology changes observed in in vivo toxicology studies. She has been a Diplomate of the American College of Veterinary Pathologists since 2011.
Selected Publications
- Cora MC, Kooistra L, Travlos G. 2015. Vaginal Cytology of the Laboratory Rat and Mouse: Review and Criteria for the Staging of the Estrous Cycle Using Stained Vaginal Smears. Toxicol Pathol 43(6):776-93. [Abstract]
- Cora MC, Gwinn W, Wilson R, King D, Waidyanatha S, Kissling GE, Brar SS, Olivera D, Blystone C, Travlos G. 2017. A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice. Toxicol Pathol 45(5):614-623. [Abstract]
Recent Publications
NTP Reports
- National Toxicology Program. Toxicity study of Stachybotrys chartarum (CASRN 67892-26-6) administered by inhalation to B6C3F1/N mice. Toxicity report series. 2024 Oct [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity study of Stachybotrys chartarum (CASRN 67892-26-6) administered by inhalation to B6C3F1/N mice. Toxicity report series. 2024 Oct ]
- National Toxicology Program. Toxicology and carcinogenesis studies of black cohosh root extract (CASRN 84776-26-1) administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and female B6C3F1/N mice. National Toxicology Program technical report series. 2023 Dec [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicology and carcinogenesis studies of black cohosh root extract (CASRN 84776-26-1) administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and female B6C3F1/N mice. National Toxicology Program technical report series. 2023 Dec ]
- National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun ]
- National Toxicology Program. Toxicity studies of acetoin and 2,3-pentanedione administered by inhalation to Wistar Han [Crl:WI(Han)] rats and B6C3F1/N mice. Toxicity report series. 2023 Mar [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity studies of acetoin and 2,3-pentanedione administered by inhalation to Wistar Han [Crl:WI(Han)] rats and B6C3F1/N mice. Toxicity report series. 2023 Mar ]
- National Toxicology Program. Toxicity studies of sodium metavanadate and vanadyl sulfate administered in drinking water to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2023 Feb [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity studies of sodium metavanadate and vanadyl sulfate administered in drinking water to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2023 Feb ]