Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Helena Hogberg, Ph.D., joined the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) within the division of translational toxicology (DTT) as a Staff Scientist in the end of 2021. She is conducting research drawing on her broad expertise in applying in vitro methods to assessing developmental neurotoxicity (DNT) potential of chemicals. Moreover, she is leading and contributing to validation efforts both in US and Europe.
She is or has been serving on a number of governmental entities, expert groups and scientific advisory boards including OECD, U.S. EPA, EFSA, Michael J Fox Foundation, and European Commission-funded projects.
Prior to joining DTT, she was the Deputy Director of the Center for Alternatives to Animal Testing (CAAT) within the Johns Hopkins University Bloomberg School for Public Health. She received her Ph.D. her in toxicology from Stockholm University but performed her research at the European Centre for the Validation of Alternative Methods (ECVAM) in Ispra, Italy.
Recent Publications
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Hill B, Karmaus A, Hull V, Unnikrishnan A, Kleinstreuer N, Hogberg H. Enhancing toxicological interpretation and reporting of in vitro high-throughput screening data.
Frontiers in toxicology.
2026;8:1886801.
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AbstractHill B, Karmaus A, Hull V, Unnikrishnan A, Kleinstreuer N, Hogberg H. Enhancing toxicological interpretation and reporting of in vitro high-throughput screening data. Frontiers in toxicology. 2026
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Mathisen G, Whaley P, Kopainsky B, Ames H, Hoffmann S, Husøy T, Jones L, Svendsen C, Vist G, Bloch D, Cavoski A, Chiu W, Davies H, Giusti A, Hartung T, Hogberg H, Kwon S, Osborne O, Rooney A, Rousselle C, Sass J, Simanainen U, Thayer K, Wikoff D, Bearth A. Preparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMs.
NAM journal.
2026;2:100118.
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AbstractMathisen G, Whaley P, Kopainsky B, Ames H, Hoffmann S, Husøy T, Jones L, Svendsen C, Vist G, Bloch D, Cavoski A, Chiu W, Davies H, Giusti A, Hartung T, Hogberg H, Kwon S, Osborne O, Rooney A, Rousselle C, Sass J, Simanainen U, Thayer K, Wikoff D, Bearth A. Preparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMs. NAM journal. 2026
]
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Roldan N, Reinke E, Hogberg H, Stucki A, Perron M, Clippinger A. Establishing scientific confidence: human biological relevance of reconstructed human respiratory epithelium (RHRE) for assessing respiratory effects.
Frontiers in toxicology.
2026;8:1847761.
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AbstractRoldan N, Reinke E, Hogberg H, Stucki A, Perron M, Clippinger A. Establishing scientific confidence: human biological relevance of reconstructed human respiratory epithelium (RHRE) for assessing respiratory effects. Frontiers in toxicology. 2026
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Behl M, Daly F, Hogberg H, Berridge B, D'Agostino J, McDuffie J, Oh H, Brar S, Authier S. Integrating new approach methodologies and artificial intelligence to advance central nervous system toxicity prediction: lessons from preclinical and clinical case studies.
Toxicological sciences : an official journal of the Society of Toxicology.
2026 Sep 02;209(9):.
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AbstractBehl M, Daly F, Hogberg H, Berridge B, D'Agostino J, McDuffie J, Oh H, Brar S, Authier S. Integrating new approach methodologies and artificial intelligence to advance central nervous system toxicity prediction: lessons from preclinical and clinical case studies. Toxicological sciences : an official journal of the Society of Toxicology. 2026 Sep 02
]
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Hall L, Hsieh J, Marvel S, Behl M, Fritsche E, Koch K, Kreutz A, Leist M, Muriana A, Shafer T, Stanko J, Sills R, Hogberg H, McPherson C. Prioritizing chemicals for developmental neurotoxicity by integrating data from a new approach methods (NAMs) battery covering key cellular events in neurodevelopment.
Neurotoxicology.
2026 Jul;115:103485.
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AbstractHall L, Hsieh J, Marvel S, Behl M, Fritsche E, Koch K, Kreutz A, Leist M, Muriana A, Shafer T, Stanko J, Sills R, Hogberg H, McPherson C. Prioritizing chemicals for developmental neurotoxicity by integrating data from a new approach methods (NAMs) battery covering key cellular events in neurodevelopment. Neurotoxicology. 2026 Jul
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More Recent Publications from PubMed
