Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Helena Hogberg, Ph.D., joined the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) within the division of translational toxicology (DTT) as a Staff Scientist in the end of 2021. She is conducting research drawing on her broad expertise in applying in vitro methods to assessing developmental neurotoxicity (DNT) potential of chemicals. Moreover, she is leading and contributing to validation efforts both in US and Europe.
She is or has been serving on a number of governmental entities, expert groups and scientific advisory boards including OECD, U.S. EPA, EFSA, Michael J Fox Foundation, and European Commission-funded projects.
Prior to joining DTT, she was the Deputy Director of the Center for Alternatives to Animal Testing (CAAT) within the Johns Hopkins University Bloomberg School for Public Health. She received her Ph.D. her in toxicology from Stockholm University but performed her research at the European Centre for the Validation of Alternative Methods (ECVAM) in Ispra, Italy.
Recent Publications
-
Behl M, Karmaus A, Rao M, Lane T, Harris J, Sachs C, Borrel A, Oyetade O, Unnikrishnan A, Hamm J, Hogberg H. De-risking seizure liability: integrating adverse outcome pathways (AOPs), new approach methodologies (NAMs), and in silico approaches while highlighting knowledge gaps.
Toxicological sciences : an official journal of the Society of Toxicology.
2025 Oct 01;207(2):306-319.
[
AbstractBehl M, Karmaus A, Rao M, Lane T, Harris J, Sachs C, Borrel A, Oyetade O, Unnikrishnan A, Hamm J, Hogberg H. De-risking seizure liability: integrating adverse outcome pathways (AOPs), new approach methodologies (NAMs), and in silico approaches while highlighting knowledge gaps. Toxicological sciences : an official journal of the Society of Toxicology. 2025 Oct 01
]
-
Yang S, Carstens K, Ipaye I, Chen X, Hogberg H, Kleinstreuer N, Knudsen T, Xia M. High-throughput cytokine detection platform for evaluation of chemical induced microglial activation.
SLAS technology.
2025 Sep 10;35:100347.
[
AbstractYang S, Carstens K, Ipaye I, Chen X, Hogberg H, Kleinstreuer N, Knudsen T, Xia M. High-throughput cytokine detection platform for evaluation of chemical induced microglial activation. SLAS technology. 2025 Sep 10
]
-
Oyetade O, Allen D, Carder J, Farley-Dawson E, Reinke E, Marko S, Kleinstreuer N, Hogberg H. Ways to broaden the awareness, consideration and adoption of new approach methodologies (NAMs).
ALTEX.
2025 Jun 26 [Epub ahead of print].
[
AbstractOyetade O, Allen D, Carder J, Farley-Dawson E, Reinke E, Marko S, Kleinstreuer N, Hogberg H. Ways to broaden the awareness, consideration and adoption of new approach methodologies (NAMs). ALTEX. 2025 Jun 26
]
-
Hogberg H, Fritsche E, Gröters S, Kovi R, Rao D, Terron A, Winter M. 2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives.
Toxicologic pathology.
2025 Jun;53(4):305-320.
[
AbstractHogberg H, Fritsche E, Gröters S, Kovi R, Rao D, Terron A, Winter M. 2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives. Toxicologic pathology. 2025 Jun
]
-
Tieghi R, Rath M, Moreira-Filho J, Wellnitz J, Martin H, Gates K, Hogberg H, Kleinstreuer N, Tropsha A, Muratov E. DeTox: an In-Silico Alternative to Animal Testing for Predicting Developmental Toxicity Potential.
Environmental health perspectives.
2025 May 19 [Epub ahead of print].
[
AbstractTieghi R, Rath M, Moreira-Filho J, Wellnitz J, Martin H, Gates K, Hogberg H, Kleinstreuer N, Tropsha A, Muratov E. DeTox: an In-Silico Alternative to Animal Testing for Predicting Developmental Toxicity Potential. Environmental health perspectives. 2025 May 19
]
More Recent Publications from PubMed
