Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
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Helena T. Hoegberg-Durdock, Ph.D.
Staff Scientist
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Tel 984-287-3157
[email protected]
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530 DAVIS DR (RTP)
530 Davis Drive (Keystone Bldg)
Durham, NC 27713
Helena Hogberg, Ph.D., joined the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) within the division of translational toxicology (DTT) as a Staff Scientist in the end of 2021. She is conducting research drawing on her broad expertise in applying in vitro methods to assessing developmental neurotoxicity (DNT) potential of chemicals. Moreover, she is leading and contributing to validation efforts both in US and Europe.
She is or has been serving on a number of governmental entities, expert groups and scientific advisory boards including OECD, U.S. EPA, EFSA, Michael J Fox Foundation, and European Commission-funded projects.
Prior to joining DTT, she was the Deputy Director of the Center for Alternatives to Animal Testing (CAAT) within the Johns Hopkins University Bloomberg School for Public Health. She received her Ph.D. her in toxicology from Stockholm University but performed her research at the European Centre for the Validation of Alternative Methods (ECVAM) in Ispra, Italy.
Recent Publications
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Celardo I, Aschner M, Ashton R, Carstens K, Cediel-Ulloa A, Cöllen E, Crofton K, Debad S, Dreser N, Fitzpatrick S, Fritsche E, Gutsfeld S, Hardy B, Hartung T, Hessel E, Heusinkveld H, Hogberg H, Hsieh J, Kanda Y, Knight G, Knudsen T, Koch K, Kuchovska E, Mangas I, Marty M, Melching-Kollmuss S, Müller I, Müller P, Myhre O, Paparella M, Pitzer E, Bal-Price A, Sachana M, Schlüppmann K, Shafer T, Schäfer J, Smirnova L, Tal T, Tanaskov Y, Tangianu S, Testa G, Ückert A, Whelan M, Leist M. Developmental neurotoxicity (DNT): A call for implementation of new approach methodologies for regulatory purposes: Summary of the 5th International Conference on DNT Testing.
ALTEX.
2025;42(2):323-349.
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AbstractCelardo I, Aschner M, Ashton R, Carstens K, Cediel-Ulloa A, Cöllen E, Crofton K, Debad S, Dreser N, Fitzpatrick S, Fritsche E, Gutsfeld S, Hardy B, Hartung T, Hessel E, Heusinkveld H, Hogberg H, Hsieh J, Kanda Y, Knight G, Knudsen T, Koch K, Kuchovska E, Mangas I, Marty M, Melching-Kollmuss S, Müller I, Müller P, Myhre O, Paparella M, Pitzer E, Bal-Price A, Sachana M, Schlüppmann K, Shafer T, Schäfer J, Smirnova L, Tal T, Tanaskov Y, Tangianu S, Testa G, Ückert A, Whelan M, Leist M. Developmental neurotoxicity (DNT): A call for implementation of new approach methodologies for regulatory purposes: Summary of the 5th International Conference on DNT Testing. ALTEX. 2025
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Cöllen E, Bartmann K, Blum J, Carstens K, Celardo I, Chatterjee N, Corvaro M, Dreser N, Fritsche E, Hartung T, Hogberg H, Knudsen T, Koch K, Kreutz A, Lislien M, Magel V, Marty M, Pallocca G, Bal-Price A, Rovida C, Sachana M, Shafer T, Smirnova L, Suciu I, Tanaskov Y, Tangianu S, Wolfbeisz C, Leist M. Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing.
ALTEX.
2025;42(2):308-322.
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AbstractCöllen E, Bartmann K, Blum J, Carstens K, Celardo I, Chatterjee N, Corvaro M, Dreser N, Fritsche E, Hartung T, Hogberg H, Knudsen T, Koch K, Kreutz A, Lislien M, Magel V, Marty M, Pallocca G, Bal-Price A, Rovida C, Sachana M, Shafer T, Smirnova L, Suciu I, Tanaskov Y, Tangianu S, Wolfbeisz C, Leist M. Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing. ALTEX. 2025
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Debad S, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg H, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer T, Smirnova L, Talpos J, Tanguay R, Terron A, Bandele O. State of the science on assessing developmental neurotoxicity using new approach methods.
ALTEX.
2025;42(1):121-144.
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AbstractDebad S, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg H, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer T, Smirnova L, Talpos J, Tanguay R, Terron A, Bandele O. State of the science on assessing developmental neurotoxicity using new approach methods. ALTEX. 2025
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Kreutz A, Chang X, Hogberg H, Wetmore B. Advancing understanding of human variability through toxicokinetic modeling, in vitro-in vivo extrapolation, and new approach methodologies.
Human genomics.
2024 Nov 21;18(1):129.
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AbstractKreutz A, Chang X, Hogberg H, Wetmore B. Advancing understanding of human variability through toxicokinetic modeling, in vitro-in vivo extrapolation, and new approach methodologies. Human genomics. 2024 Nov 21
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Kreutz A, Oyetade O, Chang X, Hsieh J, Behl M, Allen D, Kleinstreuer N, Hogberg H. Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) to Prioritize Aromatic Organophosphorus Flame Retardants.
Toxics.
2024 Jun 18;12(6):.
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AbstractKreutz A, Oyetade O, Chang X, Hsieh J, Behl M, Allen D, Kleinstreuer N, Hogberg H. Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) to Prioritize Aromatic Organophosphorus Flame Retardants. Toxics. 2024 Jun 18
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More Recent Publications from PubMed
