
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
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Helen C. Cunny, Ph.D., D.A.B.T.
Toxicologist -
Tel 984-287-3123
[email protected] -
P.O. Box 12233Mail Drop K2-06Durham, NC 27709
Helen Cunny, Ph.D., is a toxicologist and serves as a project officer in the Office of Program Operations for the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina. Cunny provides expertise in the conduct of long and short-term toxicity studies designed to provide information on the potential hazardous effects of environmental chemicals for use in human health risk assessments.
As a project officer, Cunny is involved in the design, conduct, interpretation, and reporting of research and testing activities. Studies are conducted using various models and a multidisciplinary approach. Throughout her career, she has been especially interested in testing for reproductive and developmental toxicants. She has also been an invited participant on numerous national and international reproductive and developmental toxicology committees.
Cunny received her B.S. in biology from Belhaven College in Jackson, Mississippi, and her Ph.D. in toxicology from the University of Arkansas for Medical Sciences in Little Rock, Arkansas. Prior to joining NIEHS, she worked at the FDA’s National Center for Toxicological Research in the Division of Reproductive and Developmental Toxicology and at Rhone-Poulenc, an international chemical company. In this corporate toxicologist position, Cunny designed toxicology testing regimens for new and existing products, performed human health risk assessments, and advised product development divisions within the company. These activities involved ascertaining the safety or relative risks of a wide variety of materials including agricultural products, veterinary drugs, industrial chemicals and genetically modified products.
Recent Publications
- Lahiani M, Gokulan K, Sutherland V, Cunny H, Cerniglia C, Khare S. Early Developmental Exposure to Triclosan Impacts Fecal Microbial Populations, IgA and Functional Activities of the Rat Microbiome. Journal of xenobiotics. 2024 Feb 01;14(1):193-213. [ AbstractLahiani M, Gokulan K, Sutherland V, Cunny H, Cerniglia C, Khare S. Early Developmental Exposure to Triclosan Impacts Fecal Microbial Populations, IgA and Functional Activities of the Rat Microbiome. Journal of xenobiotics. 2024 Feb 01 ]
- Harris S, McBride S, Smith M, Cunny H, Shockley K. Analysis of incidence data in developmental toxicity studies: Statistical tests to account for litter effects in fetal defect data. Birth defects research. 2023 Feb 01;115(3):327-337. [ AbstractHarris S, McBride S, Smith M, Cunny H, Shockley K. Analysis of incidence data in developmental toxicity studies: Statistical tests to account for litter effects in fetal defect data. Birth defects research. 2023 Feb 01 ]
- Taylor-LaPole A, Cunny H, Shockley K. Statistical Analysis of Rodent Body Weight Data is Robust to Departures from Normality in Historical National Toxicology Program Studies Dated 1980-2013. Journal of young investigators. 2022 Jul;25(7):1-12. [ AbstractTaylor-LaPole A, Cunny H, Shockley K. Statistical Analysis of Rodent Body Weight Data is Robust to Departures from Normality in Historical National Toxicology Program Studies Dated 1980-2013. Journal of young investigators. 2022 Jul ]
- Mutlu E, Pierfelice J, McIntyre B, Cunny H, Kissling G, Burback B, Waidyanatha S. Simultaneous Quantitation of 2-Hydroxy-4-Methoxybenzophenone, a Sunscreen Ingredient, and its Metabolites in Harlan Sprague Dawley Rat Plasma Following Perinatal Dietary Exposure. Journal of analytical toxicology. 2017 Nov 01;41(9):744-754. [ AbstractMutlu E, Pierfelice J, McIntyre B, Cunny H, Kissling G, Burback B, Waidyanatha S. Simultaneous Quantitation of 2-Hydroxy-4-Methoxybenzophenone, a Sunscreen Ingredient, and its Metabolites in Harlan Sprague Dawley Rat Plasma Following Perinatal Dietary Exposure. Journal of analytical toxicology. 2017 Nov 01 ]
- Roberts G, Waidyanatha S, Kissling G, Fletcher B, Silinski M, Fennell T, Cunny H, Robinson V, Blystone C. Exposure to butyl paraben during gestation and lactation in Hsd:Sprague dawley SD rats via dosed feed. Toxicology reports. 2016;3:774-783. [ AbstractRoberts G, Waidyanatha S, Kissling G, Fletcher B, Silinski M, Fennell T, Cunny H, Robinson V, Blystone C. Exposure to butyl paraben during gestation and lactation in Hsd:Sprague dawley SD rats via dosed feed. Toxicology reports. 2016 ]
NTP Reports
- National Toxicology Program. Toxicity study of Stachybotrys chartarum (CASRN 67892-26-6) administered by inhalation to B6C3F1/N mice. Toxicity report series. 2024 Oct [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity study of Stachybotrys chartarum (CASRN 67892-26-6) administered by inhalation to B6C3F1/N mice. Toxicity report series. 2024 Oct ]
- National Toxicology Program. Toxicology and carcinogenesis study of triclosan administered dermally to B6C3F1/N mice. National Toxicology Program technical report series. 2024 May [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicology and carcinogenesis study of triclosan administered dermally to B6C3F1/N mice. National Toxicology Program technical report series. 2024 May ]
- National Toxicology Program. Toxicology and carcinogenesis studies of black cohosh root extract (CASRN 84776-26-1) administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and female B6C3F1/N mice. National Toxicology Program technical report series. 2023 Dec [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicology and carcinogenesis studies of black cohosh root extract (CASRN 84776-26-1) administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and female B6C3F1/N mice. National Toxicology Program technical report series. 2023 Dec ]
- National Toxicology Program. NTP Research Report on the Trend Test for Binary Data with Survivability and Clustering Adjustments: Research Report 19 NTP Research Reports. 2023 Nov [Epub ahead of print]. [ AbstractNational Toxicology Program. NTP Research Report on the Trend Test for Binary Data with Survivability and Clustering Adjustments: Research Report 19 NTP Research Reports. 2023 Nov ]
- National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun ]