Genome Integrity & Structural Biology Laboratory
When & Where:
| Time | Day of Week | Location |
|---|---|---|
| 1:00 p.m. | Thursdays | F193 unless indicated |
2023
| Date | Speaker | Topic |
|---|---|---|
| September 7 | OPEN | OPEN |
| September 14 | Borgnia group: Venkata Dandy | Time-resolved Cryo-EM Using Acoustofluidics |
| September 21 | Bill Copeland | Overview of Mitochondrial DNA Replication |
| September 28 | Dmitry Gordenin | Mutational Signatures in DNA and in RNA Genomes |
| October 5 | Tom Kunkel | New Studies of Nuclear DNA Replication Fidelity |
| October 12 | Scott Williams | Topoisomerase DNA-protein Crosslink Repair |
| October 19 | Guest Speaker | Professor Steven A. Roberts, University of Vermont. (Host: Dmitry Gordenin) |
| October 26 | Doetsch group: Anirba Kar | TBA |
| November 2 | Lars Pedersen | Structural Studies of the pmHS2 Heparosan Synthetase |
| November 9 | Kunkel group: Jessica Williams | The Mutagenic Cost of Low Fidelity DNA Ligation During Replication |
| November 16 | Guest Speaker | Dr. Samantha Lewis, University of California Berkeley. (Host: Bill Copeland) |
| November 23 | Thanksgiving | |
| November 30 | Kunkel group: Mahina Monsur | Whole Genome Study of Mutagenesis by S. cerevisiae Pol ζ |
| December 7 | Schaaper group: Niketa Bhawsinghka | Duplex Sequencing to Investigate Mutations in E. coli |
| December 14 | Holiday party | |
| December 21 | Winter Break | |
| December 28 | Winter Break |
2024 (Leap year)
| Date | Speaker | Topic |
|---|---|---|
| January 4 | Lalith Perera | Molecular Modeling at the NIEHS |
| January 11 | Williams group: Anand Jaguva Vasudevan | ZATT Functions in TOP2 DNA Protein Crosslink Repair |
| January 18 | Doetsch group: Libertad Garcia | TBA |
| January 25 | Kunkel group: Scott Lujan | Whole Genome Sequence Analysis of Replication Fidelity in Yeast |
| February 1 | Mueller group: Eugene DeRose | NMR of Problematic Proteins |
| February 8 | OPEN | |
| February 15 | Bob Petrovich | Protein Expression and Purification at the NIEHS |
| February 22 | Copeland group: Dillon King | TFAM as a Mitochondrial DNA Damage Sensor |
| February 29 | Kunkel group: Sarah Marks | Are Pol Alpha Errors Extrinsically Proofread by Pol Delta? |
| March 7 | Williams group: Percy Tumbale | Molecular Basis for DNA Ligation Fidelity |
| March 14 | Doetsch group: Natasha Degtyareva | TBA |
| March 21 | Pedersen group: Guangning Zong | Structural Studies Within the Structural Biology Core |
| March 28 | Schaaper group: Abra Granger | Characterizing dGTPase Enzyme Function in E. coli Using Molecular Dynamic Simulations |
| April 4 | Mario Borgnia, Kedar Sharma | Structural Characterization of Class I Protein Mediated Membrane Fusion |
| April 11 | Williams group: Oya Bermek | Architecture of the Herpes Replisome |
| April 18 | Kunkel group: Hunter Wilkins | The Role of Exonuclease 1 in DNA Mismatch Repair |
| April 25 | Gordenin group: Matt Dennen | APOBEC Mutagenesis in Yeast Model |
| May 2 | Paul Doetsch | TBA |
| May 9 | Kunkel group: Anu Nair | Examining the “Dislocation Hypothesis” with DNA Polymerase Theta |
| May 16 | Williams group: Dhakaram Pangeni Sharma | Repair of TOP2 DNA Protein Crosslinks |
| May 23 | OPEN | |
| May 30 | Mario Borgnia |
Seven Years of cryo-EM at the NIEHS |
| June 6 | Kunkel group: Maggie Humble | How Do Mutation Prone Polymerases Handle Oxidative Stress? |
| June 13 | Roel Schaaper | Insertion Elements |
| June 20 | Williams group: Jessica Wojtaszek | Ape2 Function in DNA Protein Crosslink Repair |
| June 27 | Geoffrey Mueller | Peanut and Tree Nut Allergies: New Diagnostics and New Therapies |
| July 4 | July 4 Holiday | |
| July 11 | Kunkel group: Logan Schuck | Fixing Mismatches from Beginning to End: MMR at Telomeres |
| July 18 | Doetsch group: Avril Powell | TBA |
| July 25 | OPEN |