
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Systems Toxicology Branch
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Stephanie L. Smith-Roe, Ph.D.
Genetic Toxicologist -
Tel 984-287-3189
Fax 919-541-3647
[email protected] -
P.O. Box 12233Mail Drop K2-17Durham, NC 27709
Stephanie Smith-Roe, Ph.D., is a genetic toxicologist in the Systems Toxicology Branch of the Division of Translational Toxicology (DTT) at NIEHS. Smith-Roe designs genetic toxicity testing strategies for the DTT and serves as the Contracting Officer’s Representative for the program’s Genetic Toxicity Testing Contract. She is the lead study scientist for the in vitro genetic toxicity testing of glyphosate (the active herbicide in Roundup products) and has investigated the genotoxic effects of other high-profile substances such as radiofrequency radiation and botanical dietary supplements. Smith-Roe has contributed to the Toxicology in the 21st Century quantitative high-throughput screening effort to prioritize chemicals for further testing, focusing on assays that detect DNA damage. Her expertise has been recognized internationally, and she has served as an International Agency for Research on Cancer (IARC) monograph work group participant. Presently, Dr. Smith-Roe is the Organization for Economic Cooperation and Development (OECD) US Technical Lead for the incorporation of error-corrected sequencing approaches into genetic toxicity testing guidelines for the detection of induced mutagenesis.
Smith-Roe acquired training in toxicology and molecular biology in the pursuit of understanding the causes and consequences of genomic instability, with an emphasis on the effects of environmental exposures. Smith-Roe received a B.S. in Zoology and Psychology (specializing in biochemistry and neuroscience) from the University of Wisconsin-Madison, obtained her Ph.D. in Environmental and Molecular Toxicology from Oregon State University, and held a Curriculum in Toxicology Postdoctoral Fellowship at the University of North Carolina at Chapel Hill. Altogether, she has published in the areas of genetic toxicology, mutagenesis, carcinogenesis, DNA replication and repair, DNA damage signaling, chromatin remodeling, and behavioral neuroscience.
Smith-Roe is active in scientific societies and organizations dedicated to research and issues related to genetic toxicology, genomic stability, mutagenesis, and carcinogenesis. She is a past President (2023 – 2024) of the Environmental Mutagenesis and Genomics Society (EMGS), where she has co-chaired several symposia, served as a Councilor to the Executive Board, and co-chaired or served on numerous committees, special interest groups, and task forces. Smith-Roe serves on the Editorial Boards for Environmental and Molecular Mutagenesis (the journal of the EMGS) and Mutation Research - Genetic Toxicology and Environmental Mutagenesis. Additionally, she is an active participant in the Health and Environmental Sciences Institute (HESI) Genetic Toxicology Technical Committee (GTTC). Smith-Roe is also a Past President (2015 – 2016) of the Genetics and Environmental Mutagenesis Society (GEMS), headquartered in Research Triangle Park, North Carolina.
Selected Publications
- Smith-Roe SL, Hobbs CA, Hull V, Todd Auman J, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine Iii CC, Salk JJ, Witt KL. Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats. Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. Epub 2023 Aug 3. PMID: 37770135; PMCID: PMC10539650. [Abstract Smith-Roe SL, Hobbs CA, Hull V, Todd Auman J, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine Iii CC, Salk JJ, Witt KL. Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats. Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. Epub 2023 Aug 3. PMID: 37770135; PMCID: PMC10539650.]
- Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk CL, Young R, Zhang S, Minocherhomji S. 2023. Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment. Mutat Res Rev Mutat Res. 2023 Aug 27;792:108466. doi: 10.1016/j.mrrev.2023.108466. Epub ahead of print. [Abstract Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk CL, Young R, Zhang S, Minocherhomji S. 2023. Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment. Mutat Res Rev Mutat Res. 2023 Aug 27;792:108466. doi: 10.1016/j.mrrev.2023.108466. Epub ahead of print.]
- Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk C, Young RR, Zhang S, Minocherhomji S. Error-corrected Next-generation Sequencing to Advance Nonclinical Genotoxicity and Carcinogenicity Testing. Nat Rev Drug Discov. 2023 Mar;22(3):165-166. doi: 10.1038/d41573-023-00014-y. [Abstract Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk C, Young RR, Zhang S, Minocherhomji S. Error-corrected Next-generation Sequencing to Advance Nonclinical Genotoxicity and Carcinogenicity Testing. Nat Rev Drug Discov. 2023 Mar;22(3):165-166. doi: 10.1038/d41573-023-00014-y.]
- Smith-Roe SL, Swartz CD, Rashid A, Christy NC, Sly JE, Chang X, Sipes NS, Shockley KR, Harris SF, McBride SJ, Larson GJ, Collins BJ, Mutlu E, Witt KL. Evaluation of the Herbicide Glyphosate, (Aminomethyl)Phosphonic Acid, and Glyphosate-based Formulations for Genotoxic Activity Using in Vitro Assays. Environ Mol Mutagen. 2023 Apr;64(4):202-233. doi: 10.1002/em.22534. [Epub 2023 Mar 7]. [Abstract Smith-Roe SL, Swartz CD, Rashid A, Christy NC, Sly JE, Chang X, Sipes NS, Shockley KR, Harris SF, McBride SJ, Larson GJ, Collins BJ, Mutlu E, Witt KL. Evaluation of the Herbicide Glyphosate, (Aminomethyl)Phosphonic Acid, and Glyphosate-based Formulations for Genotoxic Activity Using in Vitro Assays. Environ Mol Mutagen. 2023 Apr;64(4):202-233. doi: 10.1002/em.22534. [Epub 2023 Mar 7].]
- Smith-Roe SL, Garantziotis S, Church RL, Bemis JC, Torous DK, Shepard KG, Hobbs CA, Waidyanatha S, Mutlu E, Shockley KR, Kissling GE, McBride SJ, Xie G, Cristy T, Pierfelice J, Witt KL. A Cross-sectional Clinical Study in Women to Investigate Possible Genotoxicity and Hematological Abnormalities Related to the Use of Black Cohosh Botanical Dietary Supplements. Environ Mol Mutagen. 2022 Dec;63(8-9):389-399. doi: 10.1002/em.22516. [Abstract Smith-Roe SL, Garantziotis S, Church RL, Bemis JC, Torous DK, Shepard KG, Hobbs CA, Waidyanatha S, Mutlu E, Shockley KR, Kissling GE, McBride SJ, Xie G, Cristy T, Pierfelice J, Witt KL. A Cross-sectional Clinical Study in Women to Investigate Possible Genotoxicity and Hematological Abnormalities Related to the Use of Black Cohosh Botanical Dietary Supplements. Environ Mol Mutagen. 2022 Dec;63(8-9):389-399. doi: 10.1002/em.22516. ]
- Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL. Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure. Environ Mol Mutagen. 2019 Oct 21. doi: 10.1002/em.22343. [Epub ahead of print]. [Abstract Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL. Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure. Environ Mol Mutagen. 2019 Oct 21. doi: 10.1002/em.22343. [Epub ahead of print].]
- Bernacki DT, Bryce SM, Bemis JC, Dertinger SD, Witt KL, Smith-Roe SL. Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract. Environ Mol Mutagen. 2019 Sep 30. doi: 10.1002/em.22334. [Epub ahead of print]. [Abstract Bernacki DT, Bryce SM, Bemis JC, Dertinger SD, Witt KL, Smith-Roe SL. Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract. Environ Mol Mutagen. 2019 Sep 30. doi: 10.1002/em.22334. [Epub ahead of print].]
- Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV. Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data. Toxicol Sci. 2019 Aug 27. pii: kfz189. doi: 10.1093/toxsci/kfz189. [Epub ahead of print]. [Abstract Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV. Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data. Toxicol Sci. 2019 Aug 27. pii: kfz189. doi: 10.1093/toxsci/kfz189. [Epub ahead of print].]
- Ooka M, Zhao J, Shah P, Travers J, Klumpp-Thomas C, Xu X, Huang R, Ferguson S, Witt KL, Smith-Roe SL, Simeonov A, Xia M. Identification of Environmental Chemicals That Activate P53 Signaling After in Vitro Metabolic Activation. Arch Toxicol. 2022 Jul;96(7):1975-1987. doi: 10.1007/s00204-022-03291-5. [Abstract Ooka M, Zhao J, Shah P, Travers J, Klumpp-Thomas C, Xu X, Huang R, Ferguson S, Witt KL, Smith-Roe SL, Simeonov A, Xia M. Identification of Environmental Chemicals That Activate P53 Signaling After in Vitro Metabolic Activation. Arch Toxicol. 2022 Jul;96(7):1975-1987. doi: 10.1007/s00204-022-03291-5. ]
- Hsieh JH, Smith-Roe SL, Huang R, Sedykh A, Shockley KR, Auerbach SS, Merrick BA, Xia M, Tice RR, Witt KL. Identifying Compounds with Genotoxicity Potential Using Tox21 High-Throughput Screening Assays. Chem Res Toxicol. 2019 Jul 15;32(7):1384-1401. doi: 10.1021/acs.chemrestox.9b00053. Epub 2019 Jun 18. [Abstract Hsieh JH, Smith-Roe SL, Huang R, Sedykh A, Shockley KR, Auerbach SS, Merrick BA, Xia M, Tice RR, Witt KL. Identifying Compounds with Genotoxicity Potential Using Tox21 High-Throughput Screening Assays. Chem Res Toxicol. 2019 Jul 15;32(7):1384-1401. doi: 10.1021/acs.chemrestox.9b00053. Epub 2019 Jun 18.]
- Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV. How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract. Food Chem Toxicol. 2018 May 9 [Epub ahead of print] [Abstract Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV. How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract. Food Chem Toxicol. 2018 May 9 [Epub ahead of print]]
- Kogevinas M, Gwinn WM, Kriebel D, Phillips DH, Sim M, Bertke SJ, Calaf GM, Colosio C, Fritz JM, Fukushima S, Hemminki K, Jensen AA, Kolstad H, Mráz J, Nesnow S, Nylander-French LA, Parent ME, Sandy M, Smith-Roe SL, Stoner G, Suzuki T, Teixeira JP, Vodicka P, Tornero-Velez R, Guyton KZ, Grosse Y, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Vilahur N, Driscoll T, Hall A, Middleton D, Jaillet C, Mattock H, Straif K. Carcinogenicity of quinoline, styrene, and styrene-7,8-oxide. Lancet Oncol. 2018 Apr 18 [Epub ahead of print] [Abstract Kogevinas M, Gwinn WM, Kriebel D, Phillips DH, Sim M, Bertke SJ, Calaf GM, Colosio C, Fritz JM, Fukushima S, Hemminki K, Jensen AA, Kolstad H, Mráz J, Nesnow S, Nylander-French LA, Parent ME, Sandy M, Smith-Roe SL, Stoner G, Suzuki T, Teixeira JP, Vodicka P, Tornero-Velez R, Guyton KZ, Grosse Y, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Vilahur N, Driscoll T, Hall A, Middleton D, Jaillet C, Mattock H, Straif K. Carcinogenicity of quinoline, styrene, and styrene-7,8-oxide. Lancet Oncol. 2018 Apr 18 [Epub ahead of print]]
- Smith-Roe SL, Swartz CD, Shepard KG, Bryce SM, Dertinger SD, Waidyanatha S, Kissling GE, Auerbach SS, Witt KL. Black cohosh extracts and powders induce micronuclei, a biomarker of genetic damage, in human cells. Environ Mol Mutagen 2018 [Epub ahead of print] [Abstract Smith-Roe SL, Swartz CD, Shepard KG, Bryce SM, Dertinger SD, Waidyanatha S, Kissling GE, Auerbach SS, Witt KL. Black cohosh extracts and powders induce micronuclei, a biomarker of genetic damage, in human cells. Environ Mol Mutagen 2018 [Epub ahead of print]]
- Sykora P, Witt KL, Revanna P, Smith-Roe SL, Dismukes J, Lloyd DG, Engelward BP, Sobol RW. Next generation high throughput DNA damage detection platform for genotoxic compound screening. Sci Rep. 2018;8(1):2771. [Abstract Sykora P, Witt KL, Revanna P, Smith-Roe SL, Dismukes J, Lloyd DG, Engelward BP, Sobol RW. Next generation high throughput DNA damage detection platform for genotoxic compound screening. Sci Rep. 2018;8(1):2771.]
- Bryce SM, Bernacki DT, Smith-Roe SL, Witt KL, Bemis JC, Dertinger SD. Investigating the Generalizability of the MultiFlow® DNA Damage Assay. Toxicol Sci 2017 [Epub ahead of print] [Abstract Bryce SM, Bernacki DT, Smith-Roe SL, Witt KL, Bemis JC, Dertinger SD. Investigating the Generalizability of the MultiFlow® DNA Damage Assay. Toxicol Sci 2017 [Epub ahead of print]]
- Witt KL, Hsieh JH, Smith-Roe SL, Xia M, Huang R, Zhao J, Auerbach SS, Hur J, Tice RR. Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation. Environ Mol Mutagen 2017 (Epub ahead of print). [Abstract Witt KL, Hsieh JH, Smith-Roe SL, Xia M, Huang R, Zhao J, Auerbach SS, Hur J, Tice RR. Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation. Environ Mol Mutagen 2017 (Epub ahead of print).]
- Bower JJ, Vance LD, Psioda M, Smith-Roe SL, Simpson DA, Ibrahim JG, Hoadley KA, Perou CM, Kaufmann WK. Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells. NPJ Breast Cancer 2017 3:9. [Abstract Bower JJ, Vance LD, Psioda M, Smith-Roe SL, Simpson DA, Ibrahim JG, Hoadley KA, Perou CM, Kaufmann WK. Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells. NPJ Breast Cancer 2017 3:9.]
- Nishihara K, Huang R, Zhao J, Shahane SA, Witt KL, Smith-Roe SL, Tice RR, Takeda S, Xia M. Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform. Mutagenesis 2016 31(1):69-81.
- Hong HH, Hoenerhoff MJ, Ton TV, Herbert RA, Kissling GE, Hooth MJ, Behl M, Witt KL, Smith-Roe SL, Sills RC, Pandiri AR7. Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal. Toxicologic pathology 2015 43(6):872-882. [Abstract Hong HH, Hoenerhoff MJ, Ton TV, Herbert RA, Kissling GE, Hooth MJ, Behl M, Witt KL, Smith-Roe SL, Sills RC, Pandiri AR7. Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal. Toxicologic pathology 2015 43(6):872-882.]
- Smith-Roe SL, Nakamura J, Holley D, Chastain PD 2nd, Rosson GB, Simpson DA, Ridpath JR, Kaufman DG, Kaufmann WK, Bultman SJ. SWI/SNF complexes are required for full activation of the DNA-damage response. Oncotarget 2015 6(2):732-745. [Abstract Smith-Roe SL, Nakamura J, Holley D, Chastain PD 2nd, Rosson GB, Simpson DA, Ridpath JR, Kaufman DG, Kaufmann WK, Bultman SJ. SWI/SNF complexes are required for full activation of the DNA-damage response. Oncotarget 2015 6(2):732-745.]
- Wilson TE, Demarini DM, Dertinger SD, Engelward BP, Hanawalt PC, Macgregor JT, Smith-Roe SL, Witt KL, Yauk CL, Ljungman M, Schwartz JL, Klein CB. 2013. Building on the past, shaping the future: The environmental mutagenesis and genomics society. Environ Mol Mutagen, 54(3):153-7. [Abstract Wilson TE, Demarini DM, Dertinger SD, Engelward BP, Hanawalt PC, Macgregor JT, Smith-Roe SL, Witt KL, Yauk CL, Ljungman M, Schwartz JL, Klein CB. 2013. Building on the past, shaping the future: The environmental mutagenesis and genomics society. Environ Mol Mutagen, 54(3):153-7.]
- Smith-Roe SL & Bultman, SJ. 2013. Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development. Mammalian Genome, 24(1-2):21-29. [Abstract Smith-Roe SL & Bultman, SJ. 2013. Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development. Mammalian Genome, 24(1-2):21-29.]
- Smith-Roe SL, Patel SP, Zhou YC, Simpson DA, Rao S, Ibrahim J, Cordeiro-Stone M, Kaufmann WK. 2013. Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle, 12(2):332-345. [Abstract Smith-Roe SL, Patel SP, Zhou YC, Simpson DA, Rao S, Ibrahim J, Cordeiro-Stone M, Kaufmann WK. 2013. Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle, 12(2):332-345.]
- Yang Y, Durando M, Smith-Roe SL, Sproul C, Greenwalt AM, Kaufmann WK, Oh S, Hendrickson EA, Vaziri C. 2013. Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. Nucleic Acids Research, 41(4):2296-2312. [Abstract Yang Y, Durando M, Smith-Roe SL, Sproul C, Greenwalt AM, Kaufmann WK, Oh S, Hendrickson EA, Vaziri C. 2013. Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. Nucleic Acids Research, 41(4):2296-2312.]
- Smith-Roe SL, Patel SP, Simpson DA, Zhou YC, Rao S, Ibrahim JG, Kaiser-Rogers KA, Cordeiro-Stone M, Kaufmann WK. 2011. Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle, 10(10):1618 - 1624. [Abstract Smith-Roe SL, Patel SP, Simpson DA, Zhou YC, Rao S, Ibrahim JG, Kaiser-Rogers KA, Cordeiro-Stone M, Kaufmann WK. 2011. Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle, 10(10):1618 - 1624.]
- Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. 2010. Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Research, 70(12):4922-30. [Abstract Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. 2010. Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Research, 70(12):4922-30.]
- Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang T, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kacmaz K. 2010. Tipin-RPA interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. Journal of Biological Chemistry, 285(22):16562-16571. [Abstract Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang T, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kacmaz K. 2010. Tipin-RPA interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. Journal of Biological Chemistry, 285(22):16562-16571.]
- Smith-Roe SL, Loehr CV, Bildfell RJ, Fischer KA, Hegan DC, Glazer PM, Buermeyer AB. 2006. Induction of aberrant crypt foci in DNA mismatch repair-deficient mice by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Cancer Letters, 244(1):79-85. [Abstract Smith-Roe SL, Loehr CV, Bildfell RJ, Fischer KA, Hegan DC, Glazer PM, Buermeyer AB. 2006. Induction of aberrant crypt foci in DNA mismatch repair-deficient mice by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Cancer Letters, 244(1):79-85.]
- Smith-Roe SL, Hegan DC, Glazer PM, Buermeyer AB. 2006. Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Mutation Research, 594(1-2):101-112. [Abstract Smith-Roe SL, Hegan DC, Glazer PM, Buermeyer AB. 2006. Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Mutation Research, 594(1-2):101-112.]