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Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Office of Program Operations

John Sloop, Ph.D. is a staff scientist in the Chemistry and ADME (adsorption, distribution, metabolism, and excretion) Resources Group (CARG) in the Office of Program Operations for the Division of Translational Toxicology (DTT). He provides chemistry expertise to the division by participating in the design, conduct, interpretation, and reporting of DTT research utilizing traditional and cutting-edge approaches to better understand how factors in the environment may impact human health.

An analytical chemist by training, he has research experience in both atomic and molecular spectroscopy, including inductively coupled plasma-mass spectrometry (ICP-MS), inductively coupled plasma optical emission spectrometry (ICP OES), liquid chromatography-mass spectrometry (LC-MS), and gas chromatography-mass spectrometry (GC-MS) techniques. His areas of research interest include novel method development for metals via ICP instrumentation and non-targeted analysis (NTA) to identify chemical contaminants in various environmental and biological matrices.

Sloop received his B.S. in both chemistry and mathematics from Barton College (Wilson, NC) in 2016, and his Ph.D. in chemistry from Wake Forest University (Winston Salem, NC) in 2021. After leaving Wake Forest, he completed a postdoctoral research appointment at the Environmental Protection Agency (EPA) in the Center for Computational Toxicology and Exposure, with a focus on non-targeted analysis (NTA) for chemicals of emerging concern in air and drinking water samples.

Selected Publications

  • Sloop JT, Chao A, Gundersen J, Phillips AL, Sobus JR, Ulrich EM, Williams AJ, Newton SR. 2023. Demonstrating the Use of Non-targeted Analysis for Identification of Unknown Chemicals in Rapid Response Scenarios. Environ Sci Technol 57(8):3075-3084. doi:10.1021/acs.est.2c06804. [Abstract] [Full Text]
  • Sloop JT, Donati GL, Jones BT. 2022. Multi-internal standard calibration applied to inductively coupled plasma optical emission spectrometry. Anal Chim Acta 1190:339258. doi:10.1016/j.aca.2021.339258. [Abstract] [Full Text]
  • Sloop JT, Gonçalves DA, O'Brien LM, Carter JA, Jones BT, Donati GL. 2021. Evaluation of different approaches to applying the standard additions calibration method. Anal Bioanal Chem 413(5):1293-1302. doi:10.1007/s00216-020-03092-8. [Abstract] [Full Text]
  • Sloop JT, Allen SC, Carter JA, Donati GL, Jones BT. 2021. Matrix-matches two-point calibration based on the standard dilution analysis method. Microchemical Journal 160 (2021) 105740. doi:10.1016/j.microc.2020.105740. [Full Text]
  • Sloop JT, Bonilla HJB, Harville T, Jones BT, Donati GL. 2019. Automated matrix-matching calibration using standard dilution analysis with two internal standards and a simple three-port mixing chamber. Talanta 205:120160. doi:10.1016/j.talanta.2019.120160. [Abstract] [Full Text]
  • Sloop JT, Carter JA, Bierbach U, Jones BT, Donati GL. 2019. Effects of platinum-based anticancer drugs on the trace element profile of liver and kidney tissue from mice. J Trace Elem Med Biol 54:62-68. doi:10.1016/j.jtemb.2019.04.005. [Abstract] [Full Text]