Systems Toxicology Branch
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Rachel P. Frawley
Health Scientist -
Tel 984-287-3132
[email protected] -
P.O. Box 12233Mail Drop K2-15Durham, NC 27709
Rachel Frawley is a health scientist in the NIEHS Division of Translational Toxicology (DTT) in the Systems Toxicology Branch. In her current role, Rachel provides scientific support to the DTT via leadership and collaboration in the design, planning, evaluation, and reporting of toxicological research studies, with a special interest in algal toxins and immunotoxicants. In addition, Rachel coordinates the monthly DTT Science Forum, which is a venue for presentation and discussion of research and current topics that are of broad interest to the program, and the annual DTT Poster Showcase.
Prior to joining the DTT, Rachel spent 20+ years as a research scientist in the Division of Intramural Research program at NIEHS. Rachel received a B.S. in biology from Christian Brothers College in Memphis, TN, and an M.S. in microbiology from Clemson, University in Clemson, SC.
Recent Publications
- Johnson V, Rider C, Luster M, Brix A, Burleson G, Cora M, Elmore S, Frawley R, Lopez F, Mutlu E, Shockley K, Pierfelice J, Burback B, Co C, Germolec D. Immunotoxicity of N-butylbenzenesulfonamide: impacts on immune function in adult mice and developmentally exposed rats. Toxicological sciences : an official journal of the Society of Toxicology. 2023 Oct 30;196(1):71-84. [ AbstractJohnson V, Rider C, Luster M, Brix A, Burleson G, Cora M, Elmore S, Frawley R, Lopez F, Mutlu E, Shockley K, Pierfelice J, Burback B, Co C, Germolec D. Immunotoxicity of N-butylbenzenesulfonamide: impacts on immune function in adult mice and developmentally exposed rats. Toxicological sciences : an official journal of the Society of Toxicology. 2023 Oct 30 ]
- Frawley R, Germolec D, Johnson V, Gulledge T, Manheng W, White K, Shockley K, Harris S, Hooth M, Ryan K. Evaluation of skin sensitization induced by four ionic liquids. Journal of applied toxicology : JAT. 2022 Mar;42(3):392-408. [ AbstractFrawley R, Germolec D, Johnson V, Gulledge T, Manheng W, White K, Shockley K, Harris S, Hooth M, Ryan K. Evaluation of skin sensitization induced by four ionic liquids. Journal of applied toxicology : JAT. 2022 Mar ]
- Frawley R, Witt K, Cunny H, Germolec D, Jackson-Humbles D, Malarkey D, Shockley K, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling G, Manheng W, Surh I, White K, Auerbach S. Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies. Toxicology. 2020 Aug;441:152474. [ AbstractFrawley R, Witt K, Cunny H, Germolec D, Jackson-Humbles D, Malarkey D, Shockley K, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling G, Manheng W, Surh I, White K, Auerbach S. Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies. Toxicology. 2020 Aug ]
- Germolec D, Shipkowski K, Frawley R, Evans E. Markers of Inflammation. Methods in molecular biology (Clifton, N.J.). 2018;1803:57-79. [ AbstractGermolec D, Shipkowski K, Frawley R, Evans E. Markers of Inflammation. Methods in molecular biology (Clifton, N.J.). 2018 ]
- Frawley R, Smith M, Cesta M, Hayes-Bouknight S, Blystone C, Kissling G, Harris S, Germolec D. Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague-Dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days. Journal of immunotoxicology. 2018 Dec;15(1):41-52. [ AbstractFrawley R, Smith M, Cesta M, Hayes-Bouknight S, Blystone C, Kissling G, Harris S, Germolec D. Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague-Dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days. Journal of immunotoxicology. 2018 Dec ]
NTP Reports
- National Toxicology Program. Toxicity studies of select ionic liquids (1-ethyl-3-methylimidazolium chloride, 1-butyl-3-methylimidazolium chloride, 1-butyl-1-methylpyrrolidinium chloride, and n-butylpyridinium chloride) administered in drinking water to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2022 May [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity studies of select ionic liquids (1-ethyl-3-methylimidazolium chloride, 1-butyl-3-methylimidazolium chloride, 1-butyl-1-methylpyrrolidinium chloride, and n-butylpyridinium chloride) administered in drinking water to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2022 May ]
- National Toxicology Program. Toxicity studies of a gum guggul extract formulation administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2020 Jun [Epub ahead of print]. [ AbstractNational Toxicology Program. Toxicity studies of a gum guggul extract formulation administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. Toxicity report series. 2020 Jun ]