Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Mechanistic Toxicology Branch
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Wei Qu, M.D., Ph.D., M.S.
Senior Biologist -
Tel 984-287-4172
[email protected] -
P.O. Box 12233Mail Drop E1-07Durham, NC 27709
Wei Qu, M.D., Ph.D., M.S., is a Senior Biologist with the Mechanistic Toxicology Branch (MTB), Division of Translational Toxicology (DTT) of the National Institute of Environmental Health Sciences (NIEHS). She received an M.D. in Medicine and Public Health and an M.S. in Environmental Toxicology and Epidemiology from Tongji Medical University in 1982 and 1986. She also received a Ph.D. from University of North Carolina in 1996 and finished postdoctoral training at the NIEHS from 1996-1999. She joined the Inorganic Carcinogenesis Section of the National Cancer Institute on detail to the NIEHS in 1999 where she studied the mechanisms of metal-induced toxicity and cancer. In 2010 she joined the National Toxicology Program (NTP) and has worked primarily on metals carcinogenesis, with a strong emphasis on arsenic, cadmium, and lead. Since NTP was changed to DTT, she has participated in Tox21 studies and established an in vitro model for evaluating Perfluorooctanoic acid (PFOA) and Polyfluoroalkyl substances (PFAS) metabolism, accumulation, toxicokinetic, cell painting and healthy response mechanisms. Wei Qu, M.D., Ph.D., M.S., has been a member of Society of Toxicology over 20 years and has actively participated in the SOT annual meeting since 1994. She has served on the SOT Metal Specialty Section Program advisory committee and has served as a reviewer on numerous scientific journals.
Recent Publications
- Qu W, Yan Y, Gerrish K, Scappini E, Tucker C, Dixon D, Merrick B. Chronic PFOA exposure in vitro causes acquisition of multiple tumor cell characteristics in rat liver cells. Toxicology in vitro : an international journal published in association with BIBRA. 2023 Jun;89:105577. [ AbstractQu W, Yan Y, Gerrish K, Scappini E, Tucker C, Dixon D, Merrick B. Chronic PFOA exposure in vitro causes acquisition of multiple tumor cell characteristics in rat liver cells. Toxicology in vitro : an international journal published in association with BIBRA. 2023 Jun ]
- Zhan L, Zhang H, Zhang Q, Woods C, Chen Y, Xue P, Dong J, Tokar E, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes M, Andersen M, Pi J. Corrigendum to "Regulatory role of KEAP1 and NRF2 in PPARg expression and chemoresistance in human non-small-cell lung carcinoma cells" [Free Radic Biol Med. 53 (2012) 758-68. doi: 10.1016/j.freeradbiomed.2012.05.041. Epub 2012 Jun 7. PMID: 22684020]. Free radical biology & medicine. 2022 Feb 01;179:418-419. [ AbstractZhan L, Zhang H, Zhang Q, Woods C, Chen Y, Xue P, Dong J, Tokar E, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes M, Andersen M, Pi J. Corrigendum to "Regulatory role of KEAP1 and NRF2 in PPARg expression and chemoresistance in human non-small-cell lung carcinoma cells" [Free Radic Biol Med. 53 (2012) 758-68. doi: 10.1016/j.freeradbiomed.2012.05.041. Epub 2012 Jun 7. PMID: 22684020]. Free radical biology & medicine. 2022 Feb 01 ]
- Qu W, Crizer D, DeVito M, Waidyanatha S, Xia M, Houck K, Ferguson S. Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening. Toxicology in vitro : an international journal published in association with BIBRA. 2021 Jun;73:105109. [ AbstractQu W, Crizer D, DeVito M, Waidyanatha S, Xia M, Houck K, Ferguson S. Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening. Toxicology in vitro : an international journal published in association with BIBRA. 2021 Jun ]
- Gong B, Li D, Kusko R, Novoradovskaya N, Zhang Y, Wang S, Pabón-Peña C, Zhang Z, Lai K, Cai W, LoCoco J, Lader E, Richmond T, Mittal V, Liu L, Johann D, Willey J, Bushel P, Yu Y, Xu C, Chen G, Burgess D, Cawley S, Giorda K, Haseley N, Qiu F, Wilkins K, Arib H, Attwooll C, Babson K, Bao L, Bao W, Lucas A, Best H, Bhandari A, Bisgin H, Blackburn J, Blomquist T, Boardman L, Burgher B, Butler D, Chang C, Chaubey A, Chen T, Chierici M, Chin C, Close D, Conroy J, Cooley Coleman J, Craig D, Crawford E, Del Pozo A, Deveson I, Duncan D, Eterovic A, Fan X, Foox J, Furlanello C, Ghosal A, Glenn S, Guan M, Haag C, Hang X, Happe S, Hennigan B, Hipp J, Hong H, Horvath K, Hu J, Hung L, Jarosz M, Kerkhof J, Kipp B, Kreil D, Łabaj P, Lapunzina P, Li P, Li Q, Li W, Li Z, Liang Y, Liu S, Liu Z, Ma C, Marella N, Martín-Arenas R, Megherbi D, Meng Q, Mieczkowski P, Morrison T, Muzny D, Ning B, Parsons B, Paweletz C, Pirooznia M, Qu W, Raymond A, Rindler P, Ringler R, Sadikovic B, Scherer A, Schulze E, Sebra R, Shaknovich R, Shi Q, Shi T, Silla-Castro J, Smith M, López M, Song P, Stetson D, Strahl M, Stuart A, Supplee J, Szankasi P, Tan H, Tang L, Tao Y, Thakkar S, Thierry-Mieg D, Thierry-Mieg J, Thodima V, Thomas D, Tichý B, Tom N, Garcia E, Verma S, Walker K, Wang C, Wang J, Wang Y, Wen Z, Wirta V, Wu L, Xiao C, Xiao W, Xu S, Yang M, Ying J, Yip S, Zhang G, Zhang S, Zhao M, Zheng Y, Zhou X, Mason C, Mercer T, Tong W, Shi L, Jones W, Xu J. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome biology. 2021 Apr 16;22(1):109. [ AbstractGong B, Li D, Kusko R, Novoradovskaya N, Zhang Y, Wang S, Pabón-Peña C, Zhang Z, Lai K, Cai W, LoCoco J, Lader E, Richmond T, Mittal V, Liu L, Johann D, Willey J, Bushel P, Yu Y, Xu C, Chen G, Burgess D, Cawley S, Giorda K, Haseley N, Qiu F, Wilkins K, Arib H, Attwooll C, Babson K, Bao L, Bao W, Lucas A, Best H, Bhandari A, Bisgin H, Blackburn J, Blomquist T, Boardman L, Burgher B, Butler D, Chang C, Chaubey A, Chen T, Chierici M, Chin C, Close D, Conroy J, Cooley Coleman J, Craig D, Crawford E, Del Pozo A, Deveson I, Duncan D, Eterovic A, Fan X, Foox J, Furlanello C, Ghosal A, Glenn S, Guan M, Haag C, Hang X, Happe S, Hennigan B, Hipp J, Hong H, Horvath K, Hu J, Hung L, Jarosz M, Kerkhof J, Kipp B, Kreil D, Łabaj P, Lapunzina P, Li P, Li Q, Li W, Li Z, Liang Y, Liu S, Liu Z, Ma C, Marella N, Martín-Arenas R, Megherbi D, Meng Q, Mieczkowski P, Morrison T, Muzny D, Ning B, Parsons B, Paweletz C, Pirooznia M, Qu W, Raymond A, Rindler P, Ringler R, Sadikovic B, Scherer A, Schulze E, Sebra R, Shaknovich R, Shi Q, Shi T, Silla-Castro J, Smith M, López M, Song P, Stetson D, Strahl M, Stuart A, Supplee J, Szankasi P, Tan H, Tang L, Tao Y, Thakkar S, Thierry-Mieg D, Thierry-Mieg J, Thodima V, Thomas D, Tichý B, Tom N, Garcia E, Verma S, Walker K, Wang C, Wang J, Wang Y, Wen Z, Wirta V, Wu L, Xiao C, Xiao W, Xu S, Yang M, Ying J, Yip S, Zhang G, Zhang S, Zhao M, Zheng Y, Zhou X, Mason C, Mercer T, Tong W, Shi L, Jones W, Xu J. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome biology. 2021 Apr 16 ]
- Cao Z, Lin S, Zhao F, Lv Y, Qu Y, Hu X, Yu S, Song S, Lu Y, Yan H, Liu Y, Ding L, Zhu Y, Liu L, Zhang M, Wang T, Zhang W, Fu H, Jin Y, Cai J, Zhang X, Yan C, Ji S, Zhang Z, Dai J, Zhu H, Gao L, Yang Y, Li C, Zhou J, Ying B, Zheng L, Kang Q, Hu J, Zhao W, Zhang M, Yu X, Wu B, Zheng T, Liu Y, Barry Ryan P, Barr D, Qu W, Zheng Y, Shi X. Cohort profile: China National Human Biomonitoring (CNHBM)-A nationally representative, prospective cohort in Chinese population. Environment international. 2021 Jan;146:106252. [ AbstractCao Z, Lin S, Zhao F, Lv Y, Qu Y, Hu X, Yu S, Song S, Lu Y, Yan H, Liu Y, Ding L, Zhu Y, Liu L, Zhang M, Wang T, Zhang W, Fu H, Jin Y, Cai J, Zhang X, Yan C, Ji S, Zhang Z, Dai J, Zhu H, Gao L, Yang Y, Li C, Zhou J, Ying B, Zheng L, Kang Q, Hu J, Zhao W, Zhang M, Yu X, Wu B, Zheng T, Liu Y, Barry Ryan P, Barr D, Qu W, Zheng Y, Shi X. Cohort profile: China National Human Biomonitoring (CNHBM)-A nationally representative, prospective cohort in Chinese population. Environment international. 2021 Jan ]