Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
Chemist, Chemistry and Absorption, Distribution, Metabolism and Excretion Resources Group Leader
Suramya Waidyanatha, Ph.D., is a supervisory biochemist and leads the chemistry and ADME (absorption, distribution, metabolism and excretion) Resources Group (CARG) in the Division of Translational Toxicology (DTT). She designs the research needs in analytical chemistry, ADME and toxicokinetics and facilitates the use of corresponding data in the design, conduct, interpretation, and reporting of toxicology research data in peer reviewed manuscripts and government reports. Waidyanatha also administers and monitors contracts conducting ADME studies, toxicokinetics studies, and analytical chemistry activities in support of toxicology research at DTT.
Waidyanatha received her B.S. (Honors) in Chemistry from University of Colombo, Sri Lanka and her M.S in Biochemistry from University of Illinois, Chicago. She received her Ph.D. in Analytical Chemistry from University of Maine prior to joining the School of Public Health at the University of North Carolina at Chapel Hill as a Postdoctoral Fellow. She continued her career at the University of North Carolina as a Laboratory Director and a Senior Scientist where she investigated biomarkers of exposure and effect to xenobiotics. Waidyanatha joined DTT in 2008 as a chemist. She is listed as an author in over 100 peer-reviewed manuscripts and government reports.
Recent Publications
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Waidyanatha S, Fennell T, Black S, Silinski M, Knudsen G, Fernando R, Rider C. Oral toxicokinetics of the indoor air pollutant, α-pinene, and its genotoxic metabolite, α-pinene oxide, in rodents and comparison to inhalation route of exposure.
Toxicology and applied pharmacology.
2026 Aug;513:117893.
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AbstractWaidyanatha S, Fennell T, Black S, Silinski M, Knudsen G, Fernando R, Rider C. Oral toxicokinetics of the indoor air pollutant, α-pinene, and its genotoxic metabolite, α-pinene oxide, in rodents and comparison to inhalation route of exposure. Toxicology and applied pharmacology. 2026 Aug
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Johnson V, Waidyanatha S, Germolec D, Cora M, Cesta M, Shockley K, Jeffers A, Cimon K, Mutlu E, Cristy T, Pierfellice J, Luster M, Burleson G, Ryan K. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2026 Jun 16;215:116226.
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AbstractJohnson V, Waidyanatha S, Germolec D, Cora M, Cesta M, Shockley K, Jeffers A, Cimon K, Mutlu E, Cristy T, Pierfellice J, Luster M, Burleson G, Ryan K. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2026 Jun 16
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Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13
NIEHS Report Series.
2026 Apr [Epub ahead of print].
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AbstractAuerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 NIEHS Report Series. 2026 Apr
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Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12
NIEHS Report Series.
2026 Apr [Epub ahead of print].
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AbstractAuerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 NIEHS Report Series. 2026 Apr
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Eccles K, Gaston K, Green E, Waidyanatha S, Stiffler B, Harris S, Rider C, Medlock Kakaley E. Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents.
Environmental science & technology.
2026 Feb 03;60(4):2976-2987.
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AbstractEccles K, Gaston K, Green E, Waidyanatha S, Stiffler B, Harris S, Rider C, Medlock Kakaley E. Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents. Environmental science & technology. 2026 Feb 03
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