
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
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Suramya Waidyanatha, Ph.D.
Chemist, Chemistry and Absorption, Distribution, Metabolism and Excretion Resources Group Leader -
Tel 984-287-3203
[email protected] -
P.O. Box 12233Mail Drop K2-07Durham, NC 27709
Suramya Waidyanatha, Ph.D., is a supervisory biochemist and leads the chemistry and ADME (absorption, distribution, metabolism and excretion) Resources Group (CARG) in the Division of Translational Toxicology (DTT). She designs the research needs in analytical chemistry, ADME and toxicokinetics and facilitates the use of corresponding data in the design, conduct, interpretation, and reporting of toxicology research data in peer reviewed manuscripts and government reports. Waidyanatha also administers and monitors contracts conducting ADME studies, toxicokinetics studies, and analytical chemistry activities in support of toxicology research at DTT.
Waidyanatha received her B.S. (Honors) in Chemistry from University of Colombo, Sri Lanka and her M.S in Biochemistry from University of Illinois, Chicago. She received her Ph.D. in Analytical Chemistry from University of Maine prior to joining the School of Public Health at the University of North Carolina at Chapel Hill as a Postdoctoral Fellow. She continued her career at the University of North Carolina as a Laboratory Director and a Senior Scientist where she investigated biomarkers of exposure and effect to xenobiotics. Waidyanatha joined DTT in 2008 as a chemist. She is listed as an author in over 100 peer-reviewed manuscripts and government reports.
Recent Publications
- Johnson V, Rider C, Luster M, Willson C, Harris S, Stiffler B, Blake J, Mutlu E, Godfrey V, Burback B, Fernando R, Waidyanatha S, Burleson G, Germolec D. Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice. Frontiers in toxicology. 2025;7:1558639. [ AbstractJohnson V, Rider C, Luster M, Willson C, Harris S, Stiffler B, Blake J, Mutlu E, Godfrey V, Burback B, Fernando R, Waidyanatha S, Burleson G, Germolec D. Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice. Frontiers in toxicology. 2025 ]
- Silinski M, Gilliam J, Apoian J, Fletcher B, Fernando R, Waidyanatha S. HIV combination drug therapies: development and validation of an LC-MS-MS method for simultaneous quantitation of abacavir, dolutegravir, and lamivudine in rat matrices in support of toxicology studies. Journal of analytical toxicology. 2025 May 16;49(5):332-339. [ AbstractSilinski M, Gilliam J, Apoian J, Fletcher B, Fernando R, Waidyanatha S. HIV combination drug therapies: development and validation of an LC-MS-MS method for simultaneous quantitation of abacavir, dolutegravir, and lamivudine in rat matrices in support of toxicology studies. Journal of analytical toxicology. 2025 May 16 ]
- Richard A, Tao D, LeClair C, Leister W, Tretyakov K, White E, Lewis K, Sefler A, Shinn P, Collins B, Nguyen D, Ye L, Zhao T, Xu T, Williams A, Waidyanatha S, Thomas R, Tice R, Simeonov A, Huang R. Analytical Quality Evaluation of the Tox21 Compound Library. Chemical research in toxicology. 2025 Jan 20;38(1):15-41. [ AbstractRichard A, Tao D, LeClair C, Leister W, Tretyakov K, White E, Lewis K, Sefler A, Shinn P, Collins B, Nguyen D, Ye L, Zhao T, Xu T, Williams A, Waidyanatha S, Thomas R, Tice R, Simeonov A, Huang R. Analytical Quality Evaluation of the Tox21 Compound Library. Chemical research in toxicology. 2025 Jan 20 ]
- Karmaus P, Gordon S, Chen M, Motsinger-Reif A, Snyder R, Fennell T, Waidyanatha S, Fernando R, Remaley A, Fessler M. Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates. Journal of lipid research. 2024 Dec;65(12):100678. [ AbstractKarmaus P, Gordon S, Chen M, Motsinger-Reif A, Snyder R, Fennell T, Waidyanatha S, Fernando R, Remaley A, Fessler M. Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates. Journal of lipid research. 2024 Dec ]
- Panzacchi S, Belpoggi F, Bua L, Bucher J, Cora M, De Angelis L, Falcioni L, Gnudi F, Mandrioli D, Manservigi M, Manzoli I, Masten S, Menghetti I, Mutlu E, Roberts G, Shipkowski K, Sills R, Stout M, Strollo V, Tibaldi E, Tracy J, Vornoli A, Waidyanatha S. NIEHS Report on the Toxicity Studies of Nicotine Bitartrate Dihydrate (CASRN 6019-06-3) Administered in Drinking Water to Sprague Dawley Rats and Swiss Mice: NIEHS Report 11 NIEHS Report Series. 2024 Oct [Epub ahead of print]. [ AbstractPanzacchi S, Belpoggi F, Bua L, Bucher J, Cora M, De Angelis L, Falcioni L, Gnudi F, Mandrioli D, Manservigi M, Manzoli I, Masten S, Menghetti I, Mutlu E, Roberts G, Shipkowski K, Sills R, Stout M, Strollo V, Tibaldi E, Tracy J, Vornoli A, Waidyanatha S. NIEHS Report on the Toxicity Studies of Nicotine Bitartrate Dihydrate (CASRN 6019-06-3) Administered in Drinking Water to Sprague Dawley Rats and Swiss Mice: NIEHS Report 11 NIEHS Report Series. 2024 Oct ]