Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
Chemist, Chemistry and Absorption, Distribution, Metabolism and Excretion Resources Group Leader
Suramya Waidyanatha, Ph.D., is a supervisory biochemist and leads the chemistry and ADME (absorption, distribution, metabolism and excretion) Resources Group (CARG) in the Division of Translational Toxicology (DTT). She designs the research needs in analytical chemistry, ADME and toxicokinetics and facilitates the use of corresponding data in the design, conduct, interpretation, and reporting of toxicology research data in peer reviewed manuscripts and government reports. Waidyanatha also administers and monitors contracts conducting ADME studies, toxicokinetics studies, and analytical chemistry activities in support of toxicology research at DTT.
Waidyanatha received her B.S. (Honors) in Chemistry from University of Colombo, Sri Lanka and her M.S in Biochemistry from University of Illinois, Chicago. She received her Ph.D. in Analytical Chemistry from University of Maine prior to joining the School of Public Health at the University of North Carolina at Chapel Hill as a Postdoctoral Fellow. She continued her career at the University of North Carolina as a Laboratory Director and a Senior Scientist where she investigated biomarkers of exposure and effect to xenobiotics. Waidyanatha joined DTT in 2008 as a chemist. She is listed as an author in over 100 peer-reviewed manuscripts and government reports.
Recent Publications
-
Frawley R, Smith-Roe S, Cunny H, Cora M, Stinson K, Xie G, Waidyanatha S, McIntyre B, Cimon K. Evaluation of 2,2'-dimorpholinodiethyl ether (DMDEE) in pathology, perinatal, and genotoxicity studies.
Toxicology.
2026 Nov;526:154528.
[
AbstractFrawley R, Smith-Roe S, Cunny H, Cora M, Stinson K, Xie G, Waidyanatha S, McIntyre B, Cimon K. Evaluation of 2,2'-dimorpholinodiethyl ether (DMDEE) in pathology, perinatal, and genotoxicity studies. Toxicology. 2026 Nov
]
-
Overdahl K, Roberts G, Gentry E, Waidyanatha S, Dunnick J, Jarmusch A. A High-Resolution Mass Spectrometry Workflow for Xenobiotic Metabolite Discovery and Toxicity Prioritization: Disperse Orange 61 as a Case Study.
Journal of the American Society for Mass Spectrometry.
2026 Oct 27 [Epub ahead of print].
[
AbstractOverdahl K, Roberts G, Gentry E, Waidyanatha S, Dunnick J, Jarmusch A. A High-Resolution Mass Spectrometry Workflow for Xenobiotic Metabolite Discovery and Toxicity Prioritization: Disperse Orange 61 as a Case Study. Journal of the American Society for Mass Spectrometry. 2026 Oct 27
]
-
Johnson V, Waidyanatha S, Germolec D, Cora M, Cesta M, Shockley K, Jeffers A, Cimon K, Mutlu E, Cristy T, Pierfellice J, Luster M, Burleson G, Ryan K. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2026 Sep;215:116226.
[
AbstractJohnson V, Waidyanatha S, Germolec D, Cora M, Cesta M, Shockley K, Jeffers A, Cimon K, Mutlu E, Cristy T, Pierfellice J, Luster M, Burleson G, Ryan K. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2026 Sep
]
-
Waidyanatha S, Fennell T, Black S, Silinski M, Knudsen G, Fernando R, Rider C. Oral toxicokinetics of the indoor air pollutant, α-pinene, and its genotoxic metabolite, α-pinene oxide, in rodents and comparison to inhalation route of exposure.
Toxicology and applied pharmacology.
2026 Aug;513:117893.
[
AbstractWaidyanatha S, Fennell T, Black S, Silinski M, Knudsen G, Fernando R, Rider C. Oral toxicokinetics of the indoor air pollutant, α-pinene, and its genotoxic metabolite, α-pinene oxide, in rodents and comparison to inhalation route of exposure. Toxicology and applied pharmacology. 2026 Aug
]
-
Taube N, Mori M, Coulter S, Jeshurin M, House J, Nadalutti C, Delker D, Cora M, Ganta C, Cunefare D, Cunny H, Waidyanatha S, Roberts G, Sutherland V, Fallacara D, Cochran S, Ciesielska E, Ciesielski G, Santos J. Antiretroviral therapy in the peripartum period impairs post pregnancy cardiac reverse remodeling in a rodent model.
Nature communications.
2026 Jul 17;17(1):.
[
AbstractTaube N, Mori M, Coulter S, Jeshurin M, House J, Nadalutti C, Delker D, Cora M, Ganta C, Cunefare D, Cunny H, Waidyanatha S, Roberts G, Sutherland V, Fallacara D, Cochran S, Ciesielska E, Ciesielski G, Santos J. Antiretroviral therapy in the peripartum period impairs post pregnancy cardiac reverse remodeling in a rodent model. Nature communications. 2026 Jul 17
]
