Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
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Michelle J. Hooth, Ph.D., D.A.B.T.
Deputy Director for Program Operations, Division of Translational Toxicology;
Director, Office of Program Operations
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Tel 984-202-4309
Fax 919-541-4255
[email protected]
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P.O. Box 12233
Mail Drop K2-07
Durham, NC 27709
Michelle Hooth, Ph.D., D.A.B.T. is a toxicologist and Director of the Office of Program Operations in the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences. The Office of Program Operations provides tactical support for the DTT research portfolio by coordinating and managing intramural and research and development budgets, contracts and Interagency Agreements, providing program/project management expertise, and delivering certain Division-shared services like chemistry, ADME/TK, and scientific reporting of DTT/NTP’s research. Hooth is responsible for directing the work of chemists and toxicologists that also implement research activities under DTT contracts.
Hooth manages and participates in multidisciplinary teams of NIEHS/DTT scientists to develop research programs to address a broad array of toxicological study needs. She led initiatives to understand the potential toxicity and carcinogenicity of hexavalent chromium, cobalt, botanical dietary supplements and drinking water disinfection by-products and contributes to numerous peer-reviewed technical reports providing scientific data to regulatory agencies and the public.
Hooth received a B.S. (summa cum laude) in Biological Sciences from Michigan State University in 1990 and a Ph.D. in Toxicology from the University of North Carolina at Chapel Hill in 1996. She completed postdoctoral training in the Environmental Carcinogenesis Division of the National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency. She joined the NTP in 2000 and became a Diplomate of the American Board of Toxicology (ABT) in 2003. She has served on various committees of the Society of Toxicology and is a prior ABT Board Member.
Recent Publications
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Soucy N, Masten S, Caro C, Arthur A, Moore N, Hooth M, Mitkus R. Updating the Standards of Professional Competence in the Field of Toxicology: The Second Generation of Best Practice.
International journal of toxicology.
2023 Sep;42(5):430-444.
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AbstractSoucy N, Masten S, Caro C, Arthur A, Moore N, Hooth M, Mitkus R. Updating the Standards of Professional Competence in the Field of Toxicology: The Second Generation of Best Practice. International journal of toxicology. 2023 Sep
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Waidyanatha S, Weber F, Fallacara D, Harrington J, Levine K, Robinson V, Sparrow B, Stout M, Fernando R, Hooth M, Xie G, Roberts G. Corrigendum to "Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water" [Toxicol. Lett. 360 (2022) 53-61].
Toxicology letters.
2023 Jan 15;373:210.
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AbstractWaidyanatha S, Weber F, Fallacara D, Harrington J, Levine K, Robinson V, Sparrow B, Stout M, Fernando R, Hooth M, Xie G, Roberts G. Corrigendum to "Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water" [Toxicol. Lett. 360 (2022) 53-61]. Toxicology letters. 2023 Jan 15
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Waidyanatha S, Weber F, Fallacara D, Harrington J, Levine K, Robinson V, Sparrow B, Stout M, Fernando R, Hooth M, Xie G, Roberts G. Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water.
Toxicology letters.
2022 May 01;360:53-61.
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AbstractWaidyanatha S, Weber F, Fallacara D, Harrington J, Levine K, Robinson V, Sparrow B, Stout M, Fernando R, Hooth M, Xie G, Roberts G. Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water. Toxicology letters. 2022 May 01
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Frawley R, Germolec D, Johnson V, Gulledge T, Manheng W, White K, Shockley K, Harris S, Hooth M, Ryan K. Evaluation of skin sensitization induced by four ionic liquids.
Journal of applied toxicology : JAT.
2022 Mar;42(3):392-408.
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AbstractFrawley R, Germolec D, Johnson V, Gulledge T, Manheng W, White K, Shockley K, Harris S, Hooth M, Ryan K. Evaluation of skin sensitization induced by four ionic liquids. Journal of applied toxicology : JAT. 2022 Mar
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Harrington J, Haines L, Levine K, Liyanapatirana C, Essader A, Fernando R, Robinson V, Roberts G, Stout M, Hooth M, Waidyanatha S. Corrigendum to "Internal dose of vanadium in rats following repeated exposure to vanadyl sulfate and sodium orthovanadate via drinking water" [Toxicology and Applied Pharmacology 412 (2021) 115395].
Toxicology and applied pharmacology.
2021 Jul 15;423:115546.
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AbstractHarrington J, Haines L, Levine K, Liyanapatirana C, Essader A, Fernando R, Robinson V, Roberts G, Stout M, Hooth M, Waidyanatha S. Corrigendum to "Internal dose of vanadium in rats following repeated exposure to vanadyl sulfate and sodium orthovanadate via drinking water" [Toxicology and Applied Pharmacology 412 (2021) 115395]. Toxicology and applied pharmacology. 2021 Jul 15
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More Recent Publications from PubMed
Staff publications can be viewed on PubMed.