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Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Systems Toxicology Branch

Cynthia Rider, Ph.D., is a toxicologist in the Systems Toxicology Branch of the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences (NIEHS). As a study scientist, she designs and evaluates results from toxicological studies of chemicals selected for investigation by the NTP. She is particularly interested in developing and refining methods for evaluating the toxicity of mixtures to inform risk assessment. Currently, she is the project leader for polycyclic aromatic compounds, which are being used as a case study to evaluate the joint action of chemicals with component-based approaches (e.g., dose addition models). She is also leading an effort to inform the safety evaluation of complex mixtures. Toward this goal, she is using botanical dietary supplements, such as Ginkgo biloba extract, to develop methods for determining sufficient similarity of complex mixtures. Rider serves as co-chair with Danielle Carlin, Ph.D., of the NIEHS Combined Exposure/Mixtures working group, which aims to advance mixtures research throughout the Institute.

Rider received her B.S. from Tulane University, New Orleans, LA in Environmental Studies and Biology and her Ph.D. from North Carolina State University, Raleigh, NC in Environmental Toxicology. She completed post doctoral training in the Reproductive Toxicology Branch of the National Health and Environmental Effects Research Laboratory, U. S. Environmental Protection Agency and the Nicholas School of the Environment at Duke University. She joined the NTP in 2010.

Recent Publications

NTP Reports

More Recent Publications from PubMed