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Your Environment. Your Health.

Funding Opportunity Announcements

Partnerships for Environmental Public Health (PEPH)

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As a network, PEPH highlights funding opportunity announcements from NIEHS, from other institutes and centers (ICs) at the National Institutes of Health (NIH) and from other Federal partners. This section lists and describes the various funding opportunity announcements that are PEPH-related. This list will change as new funding opportunity announcements are released and others close.

NIEHS encourages investigators to submit project applications using the unsolicited research grant process (e.g., R01s). Unsolicited, investigator-initiated proposals are sent to NIH for review at the Center for Scientific Review (CSR). There are many Integrated Review Groups (IRGs) at CSR; however, those most likely to be appropriate for PEPH-related unsolicited applications include the Population Sciences and Epidemiology IRG and the Healthcare Delivery and Methodologies IRG.

When preparing your proposal, we highly encourage you to do the following:

Current Available Funding Opportunities

Application Due Date Dec 05 2022
Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional)

Invites applications to participate as a Research Center as part of the Maternal Health Research Centers of Excellence initiative. The purpose of this initiative is to generate innovative approaches to address preventable maternal mortality, decrease severe maternal morbidity, and promote maternal health equity in partnership with communities that are most affected (i.e., Blacks/African Americans, American Indians/Alaska Natives, Hispanics/Latinos, Asian Americans, Native Hawaiians and other Pacific Islanders, sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations). Persons with disabilities are also a priority population. This initiative will use an integrated multi-level approach encompassing structural, social, and biobehavioral research strategies to address the multiple contributing factors that lead to adverse maternal health outcomes and health disparities. Proposed research can address maternal health in the pre-pregnancy, pregnancy, or postpartum period, provided that the research outcomes directly address severe maternal morbidity and/or maternal mortality and equitable health care. This funding opportunity announcement runs in parallel with companion announcements that seek applications for an Implementation Science Hub/Resource Center (RFA-HD-23-037) and a Data Innovation and Coordinating Hub/Resource Center (RFA-HD-23-036). It is expected that all components of the Centers of Excellence, Research Centers, and Hubs, work collaboratively to design and implement research projects, including data collection and data sharing.

Letter of Intent Due Date: November 2, 2022

Deadline: December 5, 2022

Application Due Date Jan 05 2023
PHS 2022-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)

Enables U.S.-owned-and-operated small businesses to conduct research and development that has a strong potential for commercialization. This award and the associated PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) provide funds for small businesses to stimulate technological innovation in the private sector and strengthen the role of small business in meeting federal research and development needs. The related Small Business Technology Transfer announcements [PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) and PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)] aim to foster technology transfer through cooperative research and development between small businesses and research institutions.   

Deadlines: January 5, 2023; April 5, 2023 

Application Due Date Jan 23 2023
Community Partnerships to Advance Science for Society (ComPASS) Program

There are two funding announcements under the ComPASS program: 1) Community-led, Health Equity Structural Intervention Initiative (OT2); and 2) ) Notice of Intent to Publish a Funding Opportunity Announcement for ComPASS Coordination Center (U24 – Clinical Trial Optional). The ComPASS program aims to accelerate the science of health disparities and advance health equity research.

The Community-led, Health Equity Structural Intervention Initiative (OT2) invites applications from community organizations to work in collaboration with their research partners to develop, implement, assess, disseminate, and sustain a community-led health equity structural intervention. The intervention initiative has three phases. It starts with a two-year phase (Phase I) for planning, development, piloting (as appropriate), and building partnerships. It will be followed by a six-year intervention implementation phase (Phase II) and will conclude with a two-year phase (Phase III) for assessment, dissemination, and sustainability efforts. Receipt of an award for Phase I does not guarantee a recipient’s continuation to Phase II or Phase III of the ComPASS Program.

Office Hours: November 8, 2022. The ComPASS program team is hosting Zoom-based office hours for anyone planning to submit a Letter of Intent. Pre-registration is required. Attendees can submit questions prior to the session on the registration form or by emailing

Full Application: The ComPASS team will review the letters of intent and invite select groups to submit a full application.

The ComPASS Coordination Center (CC) will provide administration, coordination, data, and research capacity-building and training support to the ComPASS consortium. The consortium includes both community-led, health equity structural intervention projects that intervene on structural factors that create and perpetuate health inequities and health equity research hubs to provide localized technical assistance to the projects. A single coordination center will be funded as an integral part of the ComPASS Program.

Letter of Intent Due Date: November 18, 2022

Deadline: January 23, 2023

Application Due Date Jan 26 2023
Notice of Special Interest (NOSI): Administrative Supplements for Research on Sex and/or Gender Influences (Admin Supp Clinical Trial Optional)

Supports research highlighting the impact of sex and/or gender influences in human health and illness. The proposed research must address at least one objective from the five strategic goals of the 2019-2023 Trans-NIH Strategic Plan for Women's Health Research. A broad range of research topics studied at the basic, pre-clinical, translational, and clinical levels that address the role of sex and/or gender in health and disease are encouraged. Studies that explore sex or gender influences or the intersection of sex and gender are also encouraged.

Deadline: January 26, 2023

Application Due Date Jan 31 2023
Notice of Special Interest (NOSI): Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)

Encourages rigorous experimental designs, as well as the implementation of collaborative interdisciplinary research on the common causes and pathways of ill health and disease, differential risk, morbidity, and mortality, across socioecological domains and levels of influence. To help meet group- and population-level needs with culturally and contextually relevant approaches, this NOSI also encourages thoughtful incorporation of intersectionality into research by applying the NIMHD Minority Health and Health Disparities Research Framework. This NOSI will support work to address the challenges faced by women and girls concerning gendered work, lower paid positions and economic instability, gender-based violence, and unsafe housing—including when these challenges intersect with bias and discrimination associated with race, sexual orientation, disability, age, and socioeconomic status. To strengthen and accelerate multidisciplinary disparities research in women’s health, this opportunity encourages the partnership of junior and senior investigators, as well as experienced women’s health researchers, with those with expertise in health disparities.

Deadline: January 31, 2023

Application Due Date Feb 05 2023
Accelerating the Pace of Child Health Research Using Existing Data From the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed)

Supports activities proposing to conduct analyses of existing ABCD Study data to accelerate the pace of research on child health and development, including: cross-sectional and/or longitudinal analyses; development of new or advanced statistical methods; and/or integration of ABCD data with other existing datasets that share common data elements. NIEHS is interested in applications that will use ABCD data resources to examine the contribution of environmental exposures on brain and development, identify sensitive time windows of development that may confer individual susceptibility, and identify protective factors that may mitigate environmental-induced changes. An R21 funding opportunity is also open.

Deadline: February 5, 2023

Application Due Date Feb 05 2023
Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional)

Strengthens and advances NIEHS’ commitment to community-engaged research projects that respond to the identified needs of community groups and make research actionable. This award will also expand the scope and reach of projects supported through the Research to Action program, a critical part of the PEPH network. The main objectives of this program are to 1) promote community engagement in environmental health research, 2) support multi-disciplinary research to collect and characterize information about environmental health concerns of significance to a community, and 3) stimulate research translation and dissemination to community members, public health professionals and/or policymakers to inform action that will ultimately promote the reduction of exposure(s) and reduce the health impact from environmental stressors. To meet these stated objectives, applicants must propose community engaged research projects that incorporate all three elements: community engagement, research, and public health action. A fourth optional element is evaluation. See the funding announcement for descriptions of these elements.

Deadlines: February 5, 2023; June 5, 2023

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