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Hepatocyte Hypertrophy

The Digitized Atlas of Mouse Liver Lesions


Centrilobular hepatocellular hypertrophy in a CD-1 mouse.


Centrilobular hepatocytomegaly (hypertrophy) in a mouse given phenobarbital for 8 months. Note the prominent eosinophilic cytoplasm reflective of smooth endoplasmic reticulum proliferation.