Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Genome Integrity & Structural Biology Laboratory Seminar Series

Genome Integrity & Structural Biology Laboratory

When & Where:

Time Day of Week Location
1:00 p.m. Thursdays F193 unless indicated


Date Speaker Topic
September 7 OPEN OPEN
September 14 Borgnia group: Venkata Dandy Time-resolved Cryo-EM Using Acoustofluidics
September 21 Bill Copeland Overview of Mitochondrial DNA Replication
September 28 Dmitry Gordenin Mutational Signatures in DNA and in RNA Genomes
October 5 Tom Kunkel New Studies of Nuclear DNA Replication Fidelity
October 12 Scott Williams Topoisomerase DNA-protein Crosslink Repair
October 19 Guest Speaker Professor Steven A. Roberts, University of Vermont. (Host: Dmitry Gordenin)
October 26 Doetsch group: Anirba Kar TBA
November 2 Lars Pedersen Structural Studies of the pmHS2 Heparosan Synthetase
November 9 Kunkel group: Jessica Williams The Mutagenic Cost of Low Fidelity DNA Ligation During Replication
November 16 Guest Speaker Dr. Samantha Lewis, University of California Berkeley. (Host: Bill Copeland)
November 23 Thanksgiving
November 30 Kunkel group: Mahina Monsur Whole Genome Study of Mutagenesis by S. cerevisiae Pol ζ
December 7 Schaaper group: Niketa Bhawsinghka Duplex Sequencing to Investigate Mutations in E. coli
December 14 Holiday party
December 21 Winter Break
December 28 Winter Break

2024 (Leap year)

Date Speaker Topic
January 4 Lalith Perera Molecular Modeling at the NIEHS
January 11 Williams group: Anand Jaguva Vasudevan ZATT Functions in TOP2 DNA Protein Crosslink Repair
January 18 Doetsch group: Libertad Garcia TBA
January 25 Kunkel group: Scott Lujan Whole Genome Sequence Analysis of Replication Fidelity in Yeast
February 1 Mueller group: Eugene DeRose NMR of Problematic Proteins
February 8 OPEN
February 15 Bob Petrovich Protein Expression and Purification at the NIEHS
February 22 Copeland group: Dillon King TFAM as a Mitochondrial DNA Damage Sensor
February 29 Kunkel group: Sarah Marks Are Pol Alpha Errors Extrinsically Proofread by Pol Delta?
March 7 Williams group: Percy Tumbale Molecular Basis for DNA Ligation Fidelity
March 14 Doetsch group: Natasha Degtyareva TBA
March 21 Pedersen group: Guangning Zong Structural Studies Within the Structural Biology Core
March 28 Schaaper group: Abra Granger Characterizing dGTPase Enzyme Function in E. coli Using Molecular Dynamic Simulations
April 4 Mario Borgnia, Kedar Sharma Structural Characterization of Class I Protein Mediated Membrane Fusion
April 11 Williams group: Oya Bermek Architecture of the Herpes Replisome
April 18 Kunkel group: Hunter Wilkins The Role of Exonuclease 1 in DNA Mismatch Repair
April 25 Gordenin group: Matt Dennen APOBEC Mutagenesis in Yeast Model
May 2 Paul Doetsch TBA
May 9 Kunkel group: Anu Nair Examining the “Dislocation Hypothesis” with DNA Polymerase Theta
May 16 Williams group: Dhakaram Pangeni Sharma Repair of TOP2 DNA Protein Crosslinks
May 23 OPEN
May 30 Mario Borgnia

Seven Years of cryo-EM at the NIEHS

June 6 Kunkel group: Maggie Humble How Do Mutation Prone Polymerases Handle Oxidative Stress?
June 13 Roel Schaaper Insertion Elements
June 20 Williams group: Jessica Wojtaszek Ape2 Function in DNA Protein Crosslink Repair
June 27 Geoffrey Mueller Peanut and Tree Nut Allergies: New Diagnostics and New Therapies
July 4 July 4 Holiday
July 11 Kunkel group: Logan Schuck Fixing Mismatches from Beginning to End: MMR at Telomeres
July 18 Doetsch group: Avril Powell TBA
July 25 OPEN
to Top