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Janet E. Hall, M.D., M.S.
Clinical Director and Principal Investigator -
Tel 984-287-3647
janet.hall@nih.govCurriculum Vitae (379KB)
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P.O. Box 12233Mail Drop A2-03Durham, N.C. 27709
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Frederick W. Miller, M.D., Ph.D.
Deputy Chief, Clinical Research Branch and Principal Investigator -
Tel 984-287-3593
Fax 301-451-5585
millerf@mail.nih.gov -
P.O. Box 12233Mail Drop F1-09Durham, N.C. 27709
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Stavros Garantziotis, M.D.
Medical Director, NIEHS Clinical Research Unit and Principal Investigator -
Tel 984-287-4412
Fax 919-541-9854
garantziotis@niehs.nih.govCurriculum Vitae (80KB)
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P.O. Box 12233Mail Drop CU-01Durham, N.C. 27709
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Shepherd H. Schurman, M.D.
Associate Medical Director, Clinical Research Unit
Principal Investigator, Environmental Polymorphisms Registry -
Tel 984-287-4411
Fax 301-480-3416
shepherd.schurman@nih.gov -
P.O. Box 12233Mail Drop CU-01Durham, N.C. 27709
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Joan P. Packenham, Ph.D.
Director, NIEHS Office of Human Research Compliance (OHRC)
NIEHS IRB Vice-Chair
DIR CRP OCR CD -
Tel 984-287-4413
Fax 919-541-9854
packenhm@niehs.nih.gov -
P.O. Box 12233Mail Drop CU-02Durham, N.C. 27709
Research Summary
- The Office of Human Research Compliance (OHRC) supports NIEHS researchers by ensuring that human research subjects' protection is at the forefront of clinical research planning.
- The Clinical Research Unit (CRU) permits NIEHS scientists to conduct studies that involve on-site human sample collection, analysis and functional assessment.
- The Environmental Polymorphisms Registry (EPR) collects and stores DNA, so that NIEHS researchers can use it to study possible gene variation links to disease.

Many human diseases result from environmental exposures that can affect individuals who are genetically susceptible to the development of a disease. The NIEHS has an active research program that investigates the mechanisms of such diseases. The mission of the Clinical Research Branch is to enhance NIEHS-led research by:
- Translating basic laboratory findings to humans
- Studying interactions between genetic susceptibility (host factors) and environmental factors in the pathogenesis of complex human traits and diseases
- Identifying populations at risk and developing novel preventative and therapeutic strategies to combat human diseases
The Clinical Research Branch pursues this mission by:
- Developing resources and systems for NIEHS investigators involved in the conduct of human investigation
- Fostering growth in clinical research and building new areas of collaboration between basic and clinical scientists
- Providing an effective interface between investigators, health care professionals, the clinical research unit and other clinical facilities in the Research Triangle Park area.
- Developing and conducting clinical research educational programs for investigators, coordinators and administrators
- Minimizing obstacles to translational research at NIEHS
The Clinical Research Branch supports multiple NIEHS research groups that focus on a wide variety of environmental conditions including asthma, chronic obstructive pulmonary disease, cardiovascular diseases, diabetes, reproductive diseases, neurological disorders, cancer, and many others. The branch’s ultimate goal is to combat environmentally-induced human disease in three substantive ways:
- Developing better diagnostic tools to identify high risk populations for environmentally induced diseases
- Developing novel therapeutic strategies
- Developing novel preventative strategies
Support Staff
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Kim Burnett-Hoke, M.P.A.
Clinical Administrative Manager -
P.O. Box 12233Mail Drop CU-01Durham, N.C. 27709
Tel 984-287-4423
kimberly.burnett-hoke@nih.gov
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Gail Kestner
Staff Assistant -
P.O. Box 12233Mail Drop A2-03Durham, N.C. 27709
Tel 984-287-3649
Fax 301-480-3049
kestner@niehs.nih.gov
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Beverly Sellers-Robinson
Administrative Specialist -
10 Center Dr
Hatfield Clinical Research Center
Bethesda, MD 20892-1301
Tel 301-451-6269
Fax 301-451-5586
sellersb@mail.nih.gov
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