Chulabhorn Research Institute, Thailand
Network of WHO Collaborating Centres for Children’s Environmental Health
The Chulabhorn Research Institute (CRI) in Bangkok, Thailand aims to provide scientific evidence supporting the idea that gestation is a period of high sensitivity to environmental chemicals, and that exposures during early development may lead to an increased risk of disease later in life. Scientists at CRI study how exposure to environmental pollutants, such as traffic-related air pollutants, electronic waste (e-waste), and arsenic, can affect children’s health. The knowledge gained from these studies will inform national policies to protect children’s health and reduce environmental health risks.
As a hub in a global network of researchers committed to advancing children’s environmental health, the CRI Centre is:
- Promoting and assisting capacity building and awareness raising activities in environmental and occupational health, toxicology, and risk assessment.
- Promoting and conducting collaborative environmental health research, particularly as it relates to emerging national and international problems and in vulnerable groups, such as children.
- Establishing and maintaining linkages with relevant research institutions, particularly in the South-East Asia and Western Pacific regions.
- Acting as a regional Centre for training in chemical safety.
|Mail address||Chulabhorn Research Institute
54 KamphaengPhet 6 Road, Lak Si
Bangkok 10210, Thailand
|Collaborators||National Institute of Occupational and Environmental Health, Vietnam
Columbia University, USA
National Institute of Environmental Health Sciences, USA
|Chemicals/Exposures studied||Arsenic in water, air pollution, e-waste|
|Health or social effects studied||DNA damage and DNA methylation alteration|
|Population(s) studied||Children living in Thailand and Vietnam|
- Hinhumpatch P, Navasumrit P, Chaisatra K, Promvijit J, Mahidol C, Ruchirawat M. 2013. Oxidative DNA damage and repair in children exposed to low levels of arsenic in utero and during early childhood: application of salivary and urinary biomarkers. Toxicol Appl Pharmacol 273(3):569-579; doi: 10.1016/j.taap.2013.10.002.
- Intarasunanont P, Navasumrit P, Waraprasit S, Chaisatra K, Suk WA, Mahidol C, Ruchirawat M. 2012. Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in human lymphoblast cell line. Environ Health 11:31; doi: 10.1186/1476-069X-11-31.
- Fry RC, Navasumrit P, Valiathan C, Svensson JP, Hogan BJ, Luo M, Bhattacharya S, Kandjanapa K, Soontararuks S, Nookabkaew S, Mahidol C, Ruchirawat M, Samson LD. 2007. Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. PLoS Genet 3(11): e207; doi: 10.1371/journal.pgen.0030207.