Genome Integrity & Structural Biology Laboratory

When & Where

March 22nd – 23rd, 2017
EPA, Conference Room C111
RTP, North Carolina

Agenda

Wednesday, March 22

Time Event
8:00 - 9:00 a.m. Arrival and Poster set-up
9:00 - 9:15 a.m. Opening Remarks – Bill Copeland, Laboratory Chief
9:15 - 10:15 a.m. Invited Speaker
Dr. Carl Bortner, NIEHS "Technical Advances in Flow Cytometry and the Reprogramming of Cell Death"
10:15 - 10:45 a.m. Coffee Break (coffee and treats next to the welcome table outside C111)
Session 1 ‐ Tom Stanley, Session Chair
10:45 - 11:00 a.m. Monica Pillon, Stanley Lab, "Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage"
11:00 - 11:15 a.m. Jungki Min, Pedersen Lab, "Structural Analysis of Glucocorticoid Receptor β Ligand Binding Domain Complexed with Glucocorticoid Antagonist RU-486: Implication of Helix 12 in Antagonism"
11:15 - 11:45 a.m. David Shock, Wilson Lab, "Modulating the DNA Polymerase Chemical Equilibrium Through Chemical Biology"
11:45 - 1:15 p.m. Lunch (Join the speakers in the EPA Lakeside cafe)
Session 2 ‐ Jungki Min and Katie Glenn, Session Chairs
1:15 - 2:00 p.m. Poster Flash
2:00 - 2:15 p.m. Explain Photo and Cookie Contest
2:15 - 2:30 p.m. Retreat Photo
2:30 - 4:00 p.m. Poster Session and Cookie Contest (coffee and tea by the welcome table)
2:30 – 3:15 p.m. Odd numbered posters
3:15 – 4:00 p.m. Even numbered posters
4:00 - 5:00 p.m. Invited Speaker
Dr. Stephen Bell, Indiana University "Life in boiling acid"

Thursday, March 23

Time Event
8:30 - 9:00 a.m. Arrival
9:00 - 10:00 a.m. Invited Speaker
Dr. Edward Egelman, University of Virginia "The Current Revolution in Cryo-EM Yields New Insights into the Evolutionary Divergence of Helical Polymers"
10:00 – 10:15 a.m. Coffee Break (next to the welcome table outside C111)
Session 3 ‐ Monica Pillon, Session Chair
10:15 – 10:30 a.m. Mike Howard, Wilson Lab, "DNA Polymerase β uses its lyase domain in a processive search for DNA damage"
10:30 - 10:45 a.m. Natalie Saini, Gordenin Lab, "Preferred targeting of non-transcribed strand of yeast tRNA genes by APOBEC3B cytidine deaminase is counteracted by increased repair efficiency"
10:45 - 11:15 a.m. Janine Santos, Woychik Lab, "Mitochondrial Regulation of the Epigenome and Transcriptome"
11:15 - 1:15 a.m. Lunch
Session 4 – Katie Glenn, Session Chair
1:15 - 1:45 p.m. GISBL Administrative Staff: Gezell Jones and Tim Hinton
1:45 - 2:00 p.m. Oswaldo Lozoya, Woychik Lab, "Studying the role of mitochondrial function in epigenetic remodeling of the nuclear transcriptome"
2:00 - 2:15 p.m. Marta Garbacz, Kunkel Lab, "In vivo consequences of DNA polymerase epsilon deficiency in Saccharomyces cerevisiae"
2:15 - 3:15 p.m. Invited Speaker
Dr. Hong Wang, North Carolina State University "Our journey on the DNA information highway with Twin proteins: New insight into genome instability from single-molecule studies"
3:15 - 3:30 p.m. Coffee Break (next to the welcome table outside C111)
3:30 - 4:45 p.m. Alumni Session, Moderator: Thuy-Ai Nguyen
Dr. Raj Gosavi (KBI Biopharma), Dr. Misty Thomas (NC A&T State University), Dr. Bret Wallace (Symberix Inc),
Dr. Kelly Daughtry Broccio (BioResource International Inc.)
4:45 - 5:00 p.m. Closing Remarks
5:30 - ? Social at The Hickory Tavern (1156 Parkside Main St, Cary, NC 27519)