Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

Your Environment. Your Health.



Biomarkers are key molecular or cellular events that link a specific environmental exposure to a health outcome. Biomarkers play an important role in understanding the relationships between exposure to environmental chemicals, the development of chronic human diseases, and the identification of subgroups that are at increased risk for disease. Much progress has been made in identifying and validating new biomarkers that can be used in population-based studies of environmental disease.

As part of the new Genes and Environment Initiative, the NIEHS is supporting the development of new technologies that will enable scientists to study how the body responds to environmental agents. Such technologies include sensitive biomarkers that can measure subtle changes in inflammation, oxidative damage, and other pathways that can lead to disease.

What is NIEHS Doing?

NIEHS Research Efforts

Visit the Join an NIEHS Study Website

The following clinical trials are currently recruiting

  • Biomarkers of Exposure to Hazardous Substances - The ability of researchers to analyze hazardous material in waste sites has improved dramatically, however they are very limited in their ability to trace the movement of hazardous materials from Superfund sites or to prioritize and mitigate the hazards involved. The ability to predict exposure or effect of these materials on humans and their environment is still more limited. This Program consists of seven integrated projects, two research support cores, a training core, a research translation core and an administrative core to address these problems.
  • Biomarkers in Oxidative Stress Study (BOSS) - NIEHS Division of Intramural Research has established an initiative to conduct a comparative study of biomarkers of oxidative stress (BOSS) in order to find out whether a fingerprint for measurement of oxidative stress exists.
  • listing of NIEHS Biomarkers studies - is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.
  • Cross-Divisional Inflammation Faculty - The cross-divisional inflammation faculty is a trans-NIEHS collaboration on cutting-edge research related to Inflammation.

Further Reading

Content courtesy of the National Cancer Institute (NCI)

Related Health Topics

Fact Sheets

NIEHS: Your Environment. Your Health

Tox21: Understanding the Potential Health Risks of Chemicals

Research Links

For Educators

This content is available to use on your website.

Please visit NIEHS Syndication to get started.
to Top