Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44)

Program Lead

Daniel T. Shaughnessy, Ph.D.
Health Scientist Administrator

Tel 984-287-3321
Fax 919-541-0146
shaughn1@niehs.nih.gov

Program Description

NIEHS SBIR/STTR grants help small businesses develop innovative and commercially viable products or technologies to translate and communicate environmental health research to improve public health. The SBIR/STTR program uses a combination of research, technology transfer, and communication strategies to aid the mission of NIEHS. Research and training areas include:

• Exposure assessment tools such as sensors and computational tools and methods
• Tools for evaluating environmental health and safety of engineered nanomaterials
• Bio-monitoring technologies and biological response markers of exposure and response
• Assays and model systems for screening compounds for toxicity
• Intervention technologies to prevent or reduce exposures to environmental stressors
• Educational materials to support understanding of environmental health science
• Superfund Research Program - Detection and remediation technologies for contaminated sites
• NIEHS Worker Training Program - Advanced Training Technology (ATT) products for the health and safety training of hazardous materials (HAZMAT) workers, emergency responders, and skilled support personnel

For more details about NIEHS clinical trial not allowed and clinical trail allowed funding topics see pages 104-111 of the SBIR/STTR NIH, CDC, and FDA Program Descriptions and Research Topics document.

Who We Fund - is a database of Environmental Health Science Research Funded by NIEHS. Search GRANT NUMBER "R43" or "R44" for SBIR grants, and "R41" or "R42" for STTR grants.

Grant applications are accepted in response to the NIH Omnibus solicitation using the SF424 (R&R) SBIR/STTR application guide (Version E) and use the Annotated SF424 (R&R) SBIR/STTR Form Set (FORMS-E) for step-by-step instruction on how to complete the application. Be mindful that the electronic submission process for HHS SBIR and STTR grants is multi-step, and can take six to eight weeks to complete the five registrations required prior to submission.

NIEHS Participating HHS SBIR and STTR Omnibus Solicitations

• PA-19-272 - PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed
• PA-19-273 - PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required
• PA-19-270 - PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed
• PA-19-271 - PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required

SBIR/STTR Application Types Accepted by NIEHS

• For PA-19-272 - Parent SBIR [R43/R44] Clinical Trial Not Allowed and PA-19-273 - Parent SBIR [R43/R44] Clinical Trial Required – Phase I, Phase II, Fast-Track, and Direct to Phase II
• For PA-19-270 - Parent STTR [R41/R42] Clinical Trial Not Allowed and PA-19-271 - Parent STTR [R41/R42] Clinical Trial Required - Phase I, Phase II,  and Fast-Track. Direct Phase II NOT Allowed.

Annual SBIR/STTR Application Receipt Dates

• September 5, 2019
• January 6, 2020 (since January 5, 2020 is on a Sunday ) and
• April 6, 2020 (since April 5, 2020 is on a Sunday )

Other NIEHS Specific/Participating Request for Applications and Program Announcements

SBIR (R43/R44) - Phase I, Phase II and Fast-Track and Direct Phase II

• RFA-ES-20-005 - Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43/R44 Clinical Trial Not Allowed)
• Letter of Intent Due Date: December 3, 2019
• Application Due Date: January 3, 2020 by 5:00 p.m. local time of applicant organization

SBIR (R43/R44) - Phase I, and Fast-Track and Direct Phase II

• RFA-ES-20-008 - New Approaches for Incorporating Genetic Diversity into Toxicity Testing (R43/R44 Clinical Trial Not Allowed)
• Letter of Intent Due Date: January 19, 2020
• Application Due Date: February 19, 2020 by 5:00 p.m. local time of applicant organization

SBIR/STTR (SB1, R44) - The “SMALL” CRP (Up to $300,000)

• PAR-19-334 - SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, R44) - Clinical Trial Not Allowed
• Standard receipt dates until April 2022

SBIR/STTR (R44) – Phase II only

• RFA-GM-19-001 - Small Business Innovation Research (SBIR) Grant - Phase II only – Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation (SBIR) (R44 - Clinical Trial Not Allowed)
• Application Due Date: January 6, 2020 by 5:00 p.m. local time of applicant organization

General SBIR/STTR Information

• NIH SBIR/STTR FAQs
  Frequently asked questions applicable to all NIH SBIR/STTR applications and grants
• SBIR/STTR Application Process Infographic
  Step-by-step application process visual
• NIH SBIR/STTR Programs
  Description, eligibility, and associated NIH institutes
• NIH SBIR/STTR Omnibus Funding
  Description, and links to omnibus related topics
• NIEHS Small Business Programs
  General overview of NIEHS areas of interest
• Small Business Grants Homepage
  General information about SBIR and STTR grants
• Grant Tools and Strategies
  Resources from NIAID including sample applications and summary statements
• Small Business Association
  Information about federal agency SBIR/STTR programs

Contacts

Additional contact for the NIEHS SBIR and STTR Program

Lingamanaidu V. Ravichandran, Ph.D.
Health Scientist Administrator

Tel 984-287-3309
lingamanaidu.ravichandran@nih.gov

P.O. Box 12233

Mail Drop K3-05

Durham, N.C. 27709

Delivery Instructions

The contact for the Superfund SBIR program is:

Heather Henry, Ph.D.
Health Scientist Administrator, Superfund Research Program

Tel 984-287-3268
henryh@niehs.nih.gov

The contact for the Worker Training SBIR program is:

Kathy A. Ahlmark
Program Analyst

Tel 984-287-3231
ahlmark@niehs.nih.gov