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Your Environment. Your Health.

Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44)

Program Lead

Daniel Shaughnessy, Ph.D.
Daniel T. Shaughnessy, Ph.D.
Health Scientist Administrator

Tel 984-287-3321
Fax 919-541-0146
shaughn1@niehs.nih.gov

New - Free HHS Small Business Program Conference on April 26-30, 2021

Join us at the free 2021 HHS Small Business Program Conference being held virtually on April 26-30 to learn how to apply for small business funding, and much more!

This year’s conference will explore the theme Diverse Perspectives SEEDing Impactful Innovations, with a special emphasis on recruiting new innovators from diverse background.

You’ll also have the chance to schedule a 15-minute meeting with small business program staff from NIEHS and other Institutes and special topic experts to get your questions answered.

NEW - NIEHS is participating in the NIH Applicant Assistance Program (AAP)

If your company has not received an NIH SBIR/STTR award and your research area of interest aligns with the mission of the NIEHS, you may be eligible to apply for the AAP and get assistance in preparing and submitting the SBIR or STTR application.

The AAP will be accepting applications April 26 - May 20, 2021 for the September 5, 2021 submission cycle.

Check NIH AAP Application webpage for more details and for submitting the application.

Town Hall Recording

NIEHS hosted a SBIR/STTR Town Hall meeting on “Development of New Approach Methodologies to Reduce Animal Use in Toxicity Testing” on April 17, 2020 with presentations from NICEATM, EPA, FDA, DoD, 3M Corporation, Syngenta and Novartis.

The slides and presentations are available at SBIR/STTR Town Hall Meeting on NAMs.

Sensory Technology for the 21st Century Website

Are you a sensor technology developer seeking SBIR/STTR funding? SBIR.gov posted a new microsite, Sensor Technology for the 21st Century to help startups and small businesses interested in sensor technologies find relevant SBIR/STTR topics by providing a central web location for sensor-related funding topics across the federal government.

Connect With Us

Register for the SBIR-NIEHS LISTSERV to receive program updates and announcements.

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NIEHS Top 10 Resources for SBIR/STTR Applicants (199KB)

Program Description

NIEHS SBIR/STTR grants help small businesses develop innovative and commercially viable products or technologies to translate and communicate environmental health research to improve public health. The SBIR/STTR program uses a combination of research, technology transfer, and communication strategies to aid the mission of NIEHS. Research and training areas include:

  • Exposure assessment tools such as sensors and computational tools and methods
  • Tools for evaluating environmental health and safety of engineered nanomaterials
  • Bio-monitoring technologies and biological response markers of exposure and response
  • Assays and model systems for screening compounds for toxicity
  • Intervention technologies to prevent or reduce exposures to environmental stressors
  • Educational materials to support understanding of environmental health science
  • Superfund Research Program - Detection and remediation technologies for contaminated sites
  • NIEHS Worker Training Program - Advanced Training Technology (ATT) products for the health and safety training of hazardous materials (HAZMAT) workers, emergency responders, and skilled support personnel

For more details about NIEHS clinical trial not allowed and clinical trial allowed funding topics see pages 97-106 of the SBIR/STTR NIH, CDC, and FDA Program Descriptions and Research Topics document.

Who We Fund - is a database of Environmental Health Science Research Funded by NIEHS. Search GRANT NUMBER "R43" or "R44" for SBIR grants, and "R41" or "R42" for STTR grants.

Grant applications are accepted in response to the NIH Omnibus solicitation using the SF424 (R&R) SBIR/STTR application guide (Version F) and use the Annotated SF424 (R&R) SBIR/STTR Form Set (FORMS-F) for step-by-step instruction on how to complete the application. Be mindful that the electronic submission process for HHS SBIR and STTR grants is multi-step, and can take six to eight weeks to complete the five registrations required prior to submission.

NIEHS Participating HHS SBIR and STTR Omnibus Solicitations

  • PA-20-260 - PHS 2020 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed
  • PA-20-262 - PHS 2020 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required
  • PA-20-265 - PHS 2020 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed
  • PA-20-261 - PHS 2020 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required

SBIR/STTR Application Types Accepted by NIEHS

  • For PA-20-260 - ;Parent SBIR [R43/R44] Clinical Trial Not Allowed and PA-20-262 - Parent SBIR [R43/R44] Clinical Trial Required – Phase I, Phase II, Fast-Track, and Direct to Phase II
  • For PA-20-265 - Parent STTR [R41/R42] Clinical Trial Not Allowed and PA-20-261 - Parent STTR [R41/R42] Clinical Trial Required - Phase I, Phase II, and Fast-Track. Direct Phase II NOT Allowed.

Annual SBIR/STTR Application Receipt Dates

  • September 8, 2020
  • January 5, 2021 and
  • April 5, 2021

Other NIEHS Specific/Participating Request for Applications and Program Announcements

SBIR/STTR (SB1) - The “SMALL” CRP (Up to $300,000)
  • PAR-20-128 - SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1) - Clinical Trial Not Allowed
    • Standard receipt dates until April 6, 2022
  • RFA-ES-21-002 – Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R43 Clinical Trial Not Allowed) and
  • RFA-ES-21-003 – Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R41 Clinical Trial Not Allowed)
    • Letter of Intent due date: February 28, 2021
    • Application due date: March 29, 2021 • 5:00 p.m., local time of applicant organization

General SBIR/STTR Information

Contacts

Additional contact for the NIEHS SBIR and STTR Program
Lingamanaidu (Ravi) Ravichandran
Lingamanaidu V. Ravichandran, Ph.D.
Health Scientist Administrator
Tel 984-287-3309
lingamanaidu.ravichandran@nih.gov
P.O. Box 12233
Mail Drop K3-05
Durham, N.C. 27709
The contact for the Superfund SBIR program is:
Heather F. Henry, Ph.D.
Heather Henry, Ph.D.
Health Scientist Administrator, Superfund Research Program

Tel 984-287-3268
henryh@niehs.nih.gov
The contact for the Worker Training SBIR program is:
Kathy Ahlmark
Kathy A. Ahlmark
Program Analyst

Tel 984-287-3231
ahlmark@niehs.nih.gov
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