Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44)

Program Lead

Daniel Shaughnessy, Ph.D.
Daniel T. Shaughnessy, Ph.D.
Health Scientist Administrator

Tel 984-287-3321
Fax 919-541-0146
shaughn1@niehs.nih.gov

NEW - NIEHS is participating in the NIH Applicant Assistance Program (AAP)

If your company has not received an NIH SBIR/STTR award and your research area of interest aligns with the mission of the NIEHS, you may be eligible to apply for the AAP and get assistance in preparing and submitting the SBIR or STTR application.

NIH will start accepting applications for the next group of AAP participants beginning April 25, 2022. Use the AAP Application Portal to apply by Monday, May 23, 2022.

Register for the NIH AAP outreach webinar on Monday, April 25 at 2:00 p.m. ET. Not only will you learn about eligibility criteria, program information, and tips for writing your application, but you’ll also have an opportunity to ask the experts your AAP questions.

Town Hall Recording

NIEHS hosted a SBIR/STTR Town Hall meeting on “Development of New Approach Methodologies to Reduce Animal Use in Toxicity Testing” on April 17, 2020 with presentations from NICEATM, EPA, FDA, DoD, 3M Corporation, Syngenta and Novartis.

The slides and presentations are available at SBIR/STTR Town Hall Meeting on NAMs.

Sensory Technology for the 21st Century Website

Are you a sensor technology developer seeking SBIR/STTR funding? SBIR.gov posted a new microsite, Sensor Technology for the 21st Century to help startups and small businesses interested in sensor technologies find relevant SBIR/STTR topics by providing a central web location for sensor-related funding topics across the federal government.

Connect With Us

Register for the SBIR-NIEHS LISTSERV to receive program updates and announcements.

Follow us on Twitter
Twitter Icon @NIEHS

Can't find what you are looking for? email-icon email us!

NIEHS Top 10 Resources for SBIR/STTR Applicants (199KB)

Program Description

NIEHS SBIR/STTR grants help small businesses develop innovative and commercially viable products or technologies to translate and communicate environmental health research to improve public health. The SBIR/STTR program uses a combination of research, technology transfer, and communication strategies to aid the mission of NIEHS. Research and training areas include:

  • Exposure assessment tools such as sensors and computational tools and methods
  • Tools for evaluating environmental health and safety of engineered nanomaterials
  • Bio-monitoring technologies and biological response markers of exposure and response
  • Assays and model systems for screening compounds for toxicity
  • Intervention technologies to prevent or reduce exposures to environmental stressors
  • Educational materials to support understanding of environmental health science
  • Superfund Research Program - Detection and remediation technologies for contaminated sites
  • NIEHS Worker Training Program - Advanced Training Technology (ATT) products for the health and safety training of hazardous materials (HAZMAT) workers, emergency responders, and skilled support personnel

For more details about NIEHS clinical trial not allowed and clinical trial allowed funding topics see pages 82-91 of the SBIR/STTR NIH, CDC, and FDA Program Descriptions and Research Topics document.

Who We Fund - is a database of Environmental Health Science Research Funded by NIEHS. Search GRANT NUMBER "R43" or "R44" for SBIR grants, and "R41" or "R42" for STTR grants.

Grant applications are accepted in response to the NIH Omnibus solicitation using the SF424 (R&R) SBIR/STTR application guide (Version F) and use the Annotated SF424 (R&R) SBIR/STTR Form Set (FORMS-F) for step-by-step instruction on how to complete the application. Be mindful that the electronic submission process for HHS SBIR and STTR grants is multi-step, and can take six to eight weeks to complete the five registrations required prior to submission.

NIEHS Participating HHS SBIR and STTR Omnibus Solicitations

  • PA-21-259 - PHS 2021-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
  • PA-21-260 - PHS 2021-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
  • PA-21-262 - PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
  • PA-21-261 - PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)

SBIR/STTR Application Types Accepted by NIEHS

  • For PA-21-259 - Parent SBIR [R43/R44] Clinical Trial Not Allowed and PA-21-260 - Parent SBIR [R43/R44] Clinical Trial Required – Phase I, Phase II, Fast-Track, and Direct to Phase II.
  • For PA-21-261 - Parent STTR [R41/R42] Clinical Trial Not Allowed and PA-21-262 - Parent STTR [R41/R42] Clinical Trial Required - Phase I, Phase II, and Fast-Track. Direct Phase II NOT Allowed.

Annual SBIR/STTR Application Receipt Dates

  • September 7, 2021
  • January 5, 2022
  • April 5, 2022

Other NIEHS Specific/Participating Request for Applications and Program Announcements


SBIR/STTR (SB1) - The “SMALL” CRP (Up to $300,000)
  • PAR-20-128 - SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1) - Clinical Trial Not Allowed
    • Standard receipt dates until April 6, 2022
  • NIEHS SBIR RFA - NEW
  • RFA-ES-22-004 - SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)
    • Open Date (Earliest Submission Date): June 20, 2022
      Letter of Intent Due Date: June 20, 2022
      Application Due Date: July 20, 2022 by 5:00 PM local time of applicant organization.

General SBIR/STTR Information

Contacts

Additional contact for the NIEHS SBIR and STTR Program
Lingamanaidu (Ravi) Ravichandran
Lingamanaidu V. Ravichandran, Ph.D.
Health Scientist Administrator
Tel 984-287-3309
lingamanaidu.ravichandran@nih.gov
P.O. Box 12233
Mail Drop K3-05
Durham, N.C. 27709
The contact for the Superfund SBIR program is:
Heather F. Henry, Ph.D.
Heather Henry, Ph.D.
Health Scientist Administrator, Superfund Research Program

Tel 984-287-3268
henryh@niehs.nih.gov
The contact for the Worker Training SBIR program is:
Kathy Ahlmark
Kathy A. Ahlmark
Program Analyst

Tel 984-287-3231
ahlmark@niehs.nih.gov
Back
to Top