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Requests for Applications

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RFA Number Release Date Title Applications Due
NS-21-012 April 21, 2021 NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) December 15, 2021; April 15, 2022; December 15, 2022;
April 14, 2023; December 15, 2023
OD-21-006 April 16, 2021 Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional) June 11, 2021
OD-21-008 April 13, 2021 Emergency Awards: Community-engaged COVID-19 Testing Interventions among Underserved and Vulnerable Populations – RADx-UP Phase II (U01 Clinical Trial Optional) July 7, 2021
OD-21-009 April 13, 2021 Emergency Award: RADx-UP - Social, Ethical, and Behavioral Implications (SEBI) Research on Disparities in COVID-19 Testing among Underserved and Vulnerable Populations (U01 Clinical Trials Optional) July 7, 2021
MD-21-004 March 23, 2021 Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 Clinical Trial Optional) August 25, 2021
TW-21-001 March 26, 2021 Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health (GEOHealth) – Research (Collaborative U01 Clinical Trial Optional) July 8, 2021
TW-21-002 March 26, 2021 Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health (GEOHealth) – Research Training (Collaborative U2R Clinical Trial Optional) July 8, 2021
OD-21-005 March 15, 2021 Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 - Independent Clinical Trial Not Allowed) June 4, 2021
OD-21-003 March 10, 2021 Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed) October 8, 2021; August 8, 2022;
March 8, 2023
OD-21-004 March 10, 2021 Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed) October 8, 2021; August 8, 2022;
March 8, 2023
OD-21-002 February 17, 2021 Tobacco Regulatory Science (R01 Clinical Trial Optional) July 14, 2021; February 15, 2022;
July 14, 2022;
February 14, 2023
OD-20-009 February 7, 2020 Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial Not Allowed) October 8, 2021; July 8, 2022
OD-20-008 February 7, 2020 Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Not Allowed) October 8, 2021; July 8, 2022
DA-22-008 January 26, 2021 NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed) September 15, 2021
AI-20-077 January 12, 2021 Immune Development in Early Life (IDEaL) (U01 Clinical Trial Not Allowed) June 18, 2021
AI-20-078 January 12, 2021 Immune Development in Early Life (IDEaL) (U19 Clinical Trial Not Allowed) June 4, 2021
OD-20-004 December 13, 2019 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) November 3, 2021
OD-20-005 December 13, 2019 Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) November 4, 2021
OD-20-006 December 13, 2019 Small Research Grants for Analyses of Down Syndrome-related Research Data for the INCLUDE Project (R03 Clinical Trial Not Allowed) November 3, 2021
OD-19-029 September 27, 2019 The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) November 26, 2021
ES-19-011 July 31, 2019 Mechanism for Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Monthly starting November 1, 2019

View all Requests for Applications

Program Announcements

Guide Notices

NOT Number Release Date Title
NOT-ES-21-006 May 3, 2021 Request for Information (RFI): Drinking Water Contaminants of Emerging Concern for National Emerging Contaminant Research Initiative Response Date: June 2, 2021
NOT-AI-21-048 May 4, 2021 Notice of Change in Key Dates for RFA-AI-20-077, “Immune Development in Early Life (IDEaL) (U01 Clinical Trial Not Allowed)”
NOT-OD-21-118 May 7, 2021 Request for Information (RFI) on Flexibilities to Reduce Administrative Burden While Continuing to Apply the PHS Policy to Zebrafish Immediately After Hatching Response Date: August 9, 2021
NOT-OD-21-110 April 28, 2021 Implementation of Changes to the Biographical Sketch and Other Support Format Page
NOT-AI-21-049 April 28, 2021 Notice of Change in Key Dates for RFA-AI-20-078, “Immune Development in Early Life (IDEaL) (U19 Clinical Trial Not Allowed)”
NOT-OD-21-107 April 20, 2021 Publication of the Revised NIH Grants Policy Statement (Rev. April 2021) for Fiscal Year 2021
NOT-OD-21-109 April 20, 2021 Expanding Requirement for eRA Commons IDs to All Senior/Key Personnel
NOT-OD-21-113 April 23, 2021 Notice of Intent to Reissue PAR-18-845 “Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed)” and PAR-18-846 (R21 - Clinical Trial Not Allowed) as a Notice of Special Interest (NOSI)
NOT-OD-21-108 April 22, 2021 Request For Information (RFI) on Enhancing the Science for the Environmental Influences on Child Health Outcomes (ECHO) Program
NOT-DA-21-037 April 21, 2021 Notice of Change to PAR-20-238, "Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)"
NOT-OD-21-104 April 14, 2021 Reminder: Required use of FORMS-F application forms for application submission
NOT-OD-21-106 April 15, 2021 Continuation of Temporary Extension of Eligibility for the NIH K99/R00 Pathway to Independence Award During the COVID-19 Pandemic
NOT-OD-21-111 April 16, 2021 Update on Changes to NIH Requirements Regarding Proposed Human Fetal Tissue Research
NOT-TW-21-006 April 16, 2021 Notice of Pre-Application Webinar for Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health (GEOHealth), RFA-TW-21-001 (U01 Clinical Trial Optional) and RFA-TW-21-002 (U2R Clinical Trial Optional)
NOT-OD-21-084 N/A Updated Reporting Requirements for RADx-rad Grant Recipients

View all Guide Notices

The NIH Guide for Grants and Contracts is the official publication for NIH grant policies, guidelines and funding opportunities. NIH publishes the Guide daily, and issues a table of contents weekly.

Requests for Proposals

View current Requests for Proposals

Selected Extramural Publications

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