Exposure, Response, and Technology Branch (ERTB)
- Daniel T. Shaughnessy, Ph.D.
Health Scientist Administrator
- Tel 919-541-2506
- P.O. Box 12233Mail Drop K3-04Durham, N.C. 27709
Daniel Shaughnessy, Ph.D., joined the Division of Extramural Research and Training in 2006. As a postdoctoral fellow in the Laboratory of Molecular Carcinogenesis at NIEHS, he conducted research on the risks and protective effects of dietary factors on DNA damage in humans. He received a Ph.D. from the University of North Carolina at Chapel Hill in 2002 and an MSPH degree from UNC in 2000, studying the molecular mechanisms of dietary antimutagens.
Shaughnessy manages a portfolio of grants related to DNA repair and mutagenesis. He also manages grants on the development and validation of biomarkers of response to environmental stress, with a current focus on early biomarkers of mitochondrial dysfunction and altered signaling in response to environmental stress. He is the program contact for the small business programs (SBIR/STTR) at NIEHS.
Areas of Specialty:
- Genome Integrity & Environmental Stress
- Mitochondria Biology
- Small Business Programs (SBIR/STTR)
- Environmental Exposure Research
- Shaughnessy DT1, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environmental Health Perspectives 2014 122(12):1271-1278. [Abstract]
- Yauk CL, Lucas Argueso J, Auerbach SS, Awadalla P, Davis SR, Demarini DM, Douglas GR, Dubrova YE, Elespuru RK, Glover TW, Hales BF, Hurles ME, Klein CB, Lupski JR, Manchester DK, Marchetti F, Montpetit A, Mulvihill JJ, Robaire B, Robbins WA, Rouleau GA, Shaughnessy DT, Somers CM, Taylor JG 6th, Trasler J, Waters MD, Wilson TE, Witt KL, Bishop JB. Harnessing genomics to identify environmental determinants of heritable disease. Mutation research 2013 752(1):6-9. [Abstract]
- Shaughnessy DT, Gangarosa LM, Schliebe B, Umbach DM, Xu Z, MacIntosh B, Knize MG, Matthews PP, Swank AE, Sandler RS, DeMarini DM, Taylor JA. Inhibition of fried meat-induced colorectal DNA damage and altered systemic genotoxicity in humans by crucifera, chlorophyllin, and yogurt. PLoS One. 2011 Apr 25;6(4):e18707. [Abstract]
- Shaughnessy DT, Worth L Jr, Lawler CP, McAllister KA, Longley MJ, Copeland WC. Meeting report: Identification of biomarkers for early detection of mitochondrial dysfunction. Mitochondrion. 2010 Aug;10(5):579-81. Epub 2010 Mar 1. [Abstract]