Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Cholangioma

The Digitized Atlas of Mouse Liver Lesions


Because their occurrence is rare, morphological characteristics of cholangiomas are not well characterized and must be distinguished from biliary cysts. Cholangiomas are discrete nodular growths in which the proliferating biliary structures are lined by a single layer of relatively uniform cuboidal epithelium. A discrete cholangioma protruding above the natural surface of the liver.


Neoplasm is comprised of large acini lined by cuboidal epithelium with occasional papillary projections into the lumen.


This cholangioma has connective tissue stroma between acini. Higher magnification shows acini lined by tall cuboidal epithelium. The nuclear crowding and occasional nests of epithelial cells in the stroma suggests progression toward malignancy.

Back
to Top