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Necropsy Support

Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Visit the NTP Website

Sampling, Trimming and Embedding Guides

The following interactive guides and images may be helpful to those using rats and mice for regulatory type toxicity studies.

The interactive guides and images were created by David Savio and Beth Mahler. Three guides from RITA and NACAD are for organ sampling and trimming in rats and mice. These guides were originally published in Experimental Toxic Pathology, in 2003, Vol. 55, publisher: URBAN & FISCHER

  • Ruehl-Fehlert C, Kittel B, Morawietz G, Deslex P, Keenan C, Mahrt CR, Nolte T, Robinson M, Stuart BP, Deschl U; RITA Group; NACAD Group. 2003. Revised guides for organ sampling and trimming in rats and mice – Part 1. Exp Toxicol Pathol 55:91-106. [ Abstract ]
  • Kittel B, Ruehl-Fehlert C, Morawietz G, Klapwijk J, Elwell MR, Lenz B, O’Sullivan MG, Roth DR, Wadsworth PF; RITA Group; NACAD Group. 2004. Revised guides for organ sampling and trimming in rats and mice – Part 2. Exp Toxicol Pathol 55:413-431. [ Abstract ]
  • Morawietz G, Ruehl-Fehlert C, Kittel B, Bube A, Keane K, Halm S, Heuser A, Hellmann J; RITA Group; NACAD Group. 2004. Revised guides for organ sampling and trimming in rats and mice – Part 3. Exp Toxicol Pathol 55:433-449. [ Abstract ]  

Mouse Embedding Suggestions

Rat Embedding Suggestions