Necropsy Support
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Visit the NTP WebsiteSampling, Trimming and Embedding Guides
The following interactive guides and images may be helpful to those using rats and mice for regulatory type toxicity studies.
The interactive guides and images were created by David Savio and Beth Mahler. Three guides from RITA and NACAD are for organ sampling and trimming in rats and mice. These guides were originally published in Experimental Toxic Pathology, in 2003, Vol. 55, publisher: URBAN & FISCHER
- Ruehl-Fehlert C, Kittel B, Morawietz G, Deslex P, Keenan C, Mahrt CR, Nolte T, Robinson M, Stuart BP, Deschl U; RITA Group; NACAD Group. 2003. Revised guides for organ sampling and trimming in rats and mice – Part 1. Exp Toxicol Pathol 55:91-106. [ Abstract ]
- Kittel B, Ruehl-Fehlert C, Morawietz G, Klapwijk J, Elwell MR, Lenz B, O’Sullivan MG, Roth DR, Wadsworth PF; RITA Group; NACAD Group. 2004. Revised guides for organ sampling and trimming in rats and mice – Part 2. Exp Toxicol Pathol 55:413-431. [ Abstract ]
- Morawietz G, Ruehl-Fehlert C, Kittel B, Bube A, Keane K, Halm S, Heuser A, Hellmann J; RITA Group; NACAD Group. 2004. Revised guides for organ sampling and trimming in rats and mice – Part 3. Exp Toxicol Pathol 55:433-449. [ Abstract ]
Mouse Embedding Suggestions
- Adrenal Glands
- Brain L1-L4
- Brain L5-L7
- Clitoral Glands
- Eye 01
- Eye 02
- Femur
- Harderian Glands
- Heart Aorta Tongue
- Ileum Cecum Colon Rectum
- Kidney
- Larynx
- Liver
- Lungs
- Mesenteric Mandibular Bronchial Lymph Nodes
- Nasal Turbinates L1-L3
- Ovaries
- Pancreas
- Pituitary
- Preputial Glands
- Prostate Sem Ves Coag Gland Bladder
- Salivary Glands
- Skeletal Muscle Skeletal Muscle Nerve
- Skin Mammary
- Spinal Cord
- Spleen Thymus
- Stomach Duodenum Jejunum
- Testes Epididymis
- Thyroid Parathyroid Esophagus Trachea
- Uterus
- Vagina Uterine Horn Cross Section Bladder
- Zymbals
Rat Embedding Suggestions
- Adrenals
- Bladder
- Brain L1 Olfactory Bulbs
- Brain L2-L4
- Brain L5-L7
- Clitoral Gland
- Epididymis
- Eye 01
- Eye 02
- Femur
- Harderian Glands
- Heart Aorta Tongue
- Ileum Cecum Colon Rectum
- Kidney
- Larynx
- Liver
- Lung Apical Cardiac
- Lung Diaphragmatic Accessory
- Lung Left Lobe
- Mesenteric Mandibular Bronchial Lymph
- Nasal Turbinates L1-L2
- Nasal Turbinates L3
- Ovaries
- Pancreas
- Pituitary
- Preputial Glands
- Prostate Sem Ves Coag Gland
- Skeletal Muscle Nerve
- Skin Mammary
- Spinal Cord
- Spleen Thymus
- Stomach Duodenum Jejunum
- Testes
- Thyroid Parathyroid Esophagus Trachea
- Uterus
- Vagina Uterine Horn Cross Section
- Zymbals
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