Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Selected Publications

Synaptic & Developmental Plasticity Group

  1. Tyssowski KM, DeStefino NR, Cho JH, Dunn CJ, Poston RG, Carty CE, Jones RD, Chang SM, Romeo P, Wurzelmann MK, Ward JM, Andermann ML, Saha RN, Dudek SM, Gray JM. (2018) Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron 98(3):530-546. [Abstract] 
  2. Farris S, Wang Y, Ward JM, Dudek SM. (2017) Optimized Method for Robust Transcriptome Profiling of Minute Tissues Using Laser Capture Microdissection and Low-Input RNA-Seq. Front Mol Neurosci 10:185. [Abstract] 
  3. Henson MA, Tucker CJ, Zhao M, Dudek SM. (2016) Long-term depression-associated signaling is required for an in vitro model of NMDA receptor-dependent synapse pruning. Neurobiology of learning and memory S1074-7427(16):30282-30289. [Abstract]
  4. Carstens KE, Phillips ML, Pozzo-Miller L, Weinberg RJ, Dudek SM. (2016) Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons. J Neurosci. 36(23):6312-20. [Abstract]
  5. Sciolino NR, Plummer NW, Chen YW, Alexander GM, Robertson SD, Dudek SM, McElligott ZA, Jensen P (2016) Recombinase-dependent mouse lines for chemogenetic activation of genetically defined cell types. Cell Reports 15(11):2563-73. [Abstract]
  6. Alexander GM, Farris S, Pirone JR, Zheng C, Colgin LL, Dudek SM. (2016) Social and novel contexts modify hippocampal CA2 representations of space. Nature Communications 7, 10300. [Abstract]
  7. Dudek SM, Alexander GM, Farris S. (2016) Rediscovering area CA2: unique properties and functions. Nature Reviews Neuroscience 17(2):89-102. [Abstract]
  8. Evans PR, Dudek SM, Hepler JR. (2015) Regulator of G Protein Signaling 14: A Molecular Brake on Synaptic Plasticity Linked to Learning and Memory. Progress in molecular biology and translational science 133():196-206. [Abstract]
  9. Pagani JH, Zhao M, Cui Z, Williams Avram SK, Caruana DA, Dudek SM, Young WS. (2015) Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2. Molecular psychiatry 20(4):490-499. [Abstract]
  10. Saha, RN, Dudek, SM. (2013) Splitting Hares and Tortoises: a classification of neuronal immediate early gene transcription based on poised RNA polymerase II. Neuroscience 247:175-181.  [Abstract]
  11. Caruana DA, Alexander GM, Dudek SM. (2012) New insights into the regulation of synaptic plasticity from an unexpected place: Hippocampal area CA2. Learning & memory (Cold Spring Harbor, N.Y.) 19(9):391-400. [Abstract]
  12. Simons, S.B., Caruana, D.A., Zhao, M. & Dudek, S.M. (2011) Caffeine-induced synaptic potentiation in hippocampal CA2 neurons. Nature Neuroscience 15(1):23-5. [Abstract]
  13. Vellano, C.P., Lee, S.E., Dudek, S.M. & Hepler, J.R. (2011) RGS14 at the Interface of Hippocampal Signaling and Synaptic Plasticity. Trends in Pharmacological Sciences 32(11):666-674. [Abstract]
  14. Saha, R.N., Wissink, E.M., Bailey, E., Zhao, M., Fargo, D., Hwang, J., Daigle, K.R., Fenn, J.D., Adelman, K. & Dudek, S.M. (2011) Rapid activity-induced transcription of arc and other IEGs relies on poised RNA polymerase II. Nature neuroscience 14(7):848-856. [Abstract]
  15. Adams, J.P., Robinson, R.A., Hudgins, E.D., Dudek, S.M. & Wissink, E.M. (2009) NMDA receptor-independent control of transcription factors and gene expression. Neuroreport 20(16):1429-1433. [Abstract]
  16. Simons, S.B., Escobedo, Y., Yasuda, R. & Dudek, S.M. (2009) Regional differences in hippocampal calcium handling provide a cellular mechanism for limiting plasticity. Proceedings of the National Academy of Sciences of the United States of America 106(33):14080-14084. [Abstract]
  17. Lundquist, J.J. & Dudek, S.M. (2008) Differential activation of extracellular signal-regulated kinase 1 and a related complex in neuronal nuclei. Brain Cell Biol. 35(4-6):267-281. [Abstract]
  18. Bastrikova, N., Gardner, G.A., Reece, J.M., Jeromin, A. & Dudek, S.M. (2008) Synapse elimination accompanies functional plasticity in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America 105(8):3123-3127. [Abstract]
  19. Saha, R. & Dudek, S.M. (2008) Action potentials: to the nucleus and beyond. Experimental biology and medicine 233(4):385-393. [Abstract]
  20. Zhao, M. & Dudek, S.M. (2007) Synaptic plasticity (and the lack thereof) in hippocampal CA2 neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 27(44):12025-12032. [Abstract]
  21. Zhao, M., Adams, J.P. & Dudek, S.M. (2005) Pattern-dependent role of NMDA receptors in action potential generation: consequences on Extracellular Signal-Regulated Kinase activation. J. Neurosci. 25, 7032-7039. [Abstract]
  22. Adams, J.P. & Dudek, S.M. (2005) Late-phase long-term potentiation: getting to the nucleus, Nature Rev. Neurosci. 6, 737-743.  [Abstract]
  23. Dudek, S.M. & Fields, R.D. (2002) Somatic action potentials are sufficient for late-phase LTP-related cell signaling, Proc Natl Acad Sci USA 99(6), 3962-3967.  [Abstract]
  24. Dudek, S.M. & Fields, R.D. (2001) Mitogen-activated protein kinase/extracellular signal-regulated kinase activation in somatodendritic compartments: roles of action potentials, frequency, and mode of calcium entry, J Neurosci 21(2), RC122. [Abstract]
  25. Dudek, S.M. & Friedlander, M.J. (1996) Developmental down-regulation of LTD in cortical layer IV and its independence of modulation by inhibition, Neuron 16(6), 1097-1106.  [Abstract]
  26. Dudek, S.M. & Johnson, G.V.W. (1993) Transglutaminase catalyzes the formation of sodium dodecyl sulfate insoluble, Alz-50 positive polymers of tau. J. Neurochem. 61: 1159-1162.  [Abstract]
  27. Dudek, S.M. & Bear, M.F. (1993) Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. J. Neurosci. 13: 2910-2918.  [Abstract]
  28. Dudek, S.M. & Bear, M.F. (1992) Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc Natl Acad Sci USA 89(10), 4363-4367. [Abstract]
to Top