Health Assessment and Translation
Andrew A. Rooney, Ph.D.
Andrew Rooney, Ph.D., is acting Chief of the Integrative Health Assessments Branch of the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences (NIEHS). He is an active and accountable leader, supporting staff and leveraging branch expertise to address challenging public health questions through the development of impactful systematic reviews and evidence maps.
In addition to publishing environmental health assessments, Rooney is thought leader in the field, actively involved in developing risk assessment methods, systematic review guidance, and advanced informatics approaches throughout his professional career. He led the team that developed the OHAT Approach to systematic review and evidence integration – a key step in bringing systematic review methods into toxicology and environmental health. Rooney has co-authored over 100 contributions to the peer-reviewed literature and government assessments such as NTP Monographs, EPA IRIS Toxicological Reviews, and WHO Guidelines. He has also served on expert committees for U.S. and international organizations including the EPA Science Advisory Committee on Chemicals, National Academy of Sciences Engineering and Medicine, European Food Safety Authority, and World Health Organization's Chemical Risk Assessment Network.
Rooney received his Sc.B. in Biology with Honors from Brown University and completed his graduate training at the University of Florida, earning a M.S. and Ph.D. in Zoology. He was awarded a National Research Grant of Canada and completed postdoctoral fellowships in immunotoxicology at both the University of Quebec, INRS-SANTÉ and the US EPA. He later joined the US EPA’s Integrated Risk Information System Staff, where he served as a health scientist and Team Leader before joining NIEHS to work with NTP in 2009.
Recent Publications
- Lunn R, Clemons M, Blain R, Mahabir S, Mehta S, Rooney A, Singh A, Smith-Roe S, Taylor K, Tracy W, Zarco M, Fenton S. Identifying the known and unknown health hazard information for chemical disasters: a phased scoping review of the East Palestine, Ohio train derailment. Journal of exposure science & environmental epidemiology. 2025 Sep 12 [Epub ahead of print]. [ AbstractLunn R, Clemons M, Blain R, Mahabir S, Mehta S, Rooney A, Singh A, Smith-Roe S, Taylor K, Tracy W, Zarco M, Fenton S. Identifying the known and unknown health hazard information for chemical disasters: a phased scoping review of the East Palestine, Ohio train derailment. Journal of exposure science & environmental epidemiology. 2025 Sep 12 ]
- Bearth A, Kopainsky B, Jones L, Vist G, Husøy T, Svendsen C, Whaley P, Hoffmann S, Ames H, Solstad G, Bloch D, Čavoški A, Chiu W, Davenport M, Davies H, Giusti A, Hartung T, Kwon S, Osborne O, Rooney A, Rousselle C, Sass J, Wright F, Mathisen G. Exploring experiences of the regulatory toxicology system: system-level promoters and inhibitors of new approach methodologies. Archives of toxicology. 2025 Sep 09 [Epub ahead of print]. [ AbstractBearth A, Kopainsky B, Jones L, Vist G, Husøy T, Svendsen C, Whaley P, Hoffmann S, Ames H, Solstad G, Bloch D, Čavoški A, Chiu W, Davenport M, Davies H, Giusti A, Hartung T, Kwon S, Osborne O, Rooney A, Rousselle C, Sass J, Wright F, Mathisen G. Exploring experiences of the regulatory toxicology system: system-level promoters and inhibitors of new approach methodologies. Archives of toxicology. 2025 Sep 09 ]
- Taylor K, Eftim S, Rooney A. Concerns About Data and Analyses Used in Assessing Fluoride Exposure and Children's IQ Scores-Reply. JAMA pediatrics. 2025 May 12 [Epub ahead of print]. [ AbstractTaylor K, Eftim S, Rooney A. Concerns About Data and Analyses Used in Assessing Fluoride Exposure and Children's IQ Scores-Reply. JAMA pediatrics. 2025 May 12 ]
- Higgins J, Rooney A, Morgan R, Hróbjartsson A, McAleenan A, Meerpohl J, O'Connor A, Schünemann H, Verbeek J, Viswanathan M, Sterne J. Response to: ROBINS-E risk of bias tool. Environment international. 2025 May;199:109462. [ AbstractHiggins J, Rooney A, Morgan R, Hróbjartsson A, McAleenan A, Meerpohl J, O'Connor A, Schünemann H, Verbeek J, Viswanathan M, Sterne J. Response to: ROBINS-E risk of bias tool. Environment international. 2025 May ]
- Angrish M, Thayer K, Schulz B, Nowak A, Persad A, Phillips A, Rice G, Shannon T, Wilkins A, Christensen K, Radke E, Shapiro A, Taylor M, Walker V, Rooney A, Watford S. Proof-of-concept for using machine learning to facilitate data extraction for human health chemical assessments: a study protocol. Evidence-based toxicology. 2024 Nov 11;2(1):2421192. [ AbstractAngrish M, Thayer K, Schulz B, Nowak A, Persad A, Phillips A, Rice G, Shannon T, Wilkins A, Christensen K, Radke E, Shapiro A, Taylor M, Walker V, Rooney A, Watford S. Proof-of-concept for using machine learning to facilitate data extraction for human health chemical assessments: a study protocol. Evidence-based toxicology. 2024 Nov 11 ]
NTP Reports
- National Toxicology Program. NTP monograph on the state of the science concerning fluoride exposure and neurodevelopment and cognition: a systematic review. NTP monograph. 2024 Aug [Epub ahead of print]. [ AbstractNational Toxicology Program. NTP monograph on the state of the science concerning fluoride exposure and neurodevelopment and cognition: a systematic review. NTP monograph. 2024 Aug ]
- CLARITY-BPA Research Program. NTP Research Report on the Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity (CLARITY-BPA): A Compendium of Published Findings: Research Report 18 NTP Research Reports. 2021 Oct [Epub ahead of print]. [ AbstractCLARITY-BPA Research Program. NTP Research Report on the Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity (CLARITY-BPA): A Compendium of Published Findings: Research Report 18 NTP Research Reports. 2021 Oct ]
- National Toxicology Program. NTP monograph on the systematic review of traffic-related air pollution and hypertensive disorders of pregnancy. NTP monograph. 2019 Dec [Epub ahead of print]. [ AbstractNational Toxicology Program. NTP monograph on the systematic review of traffic-related air pollution and hypertensive disorders of pregnancy. NTP monograph. 2019 Dec ]
- National Toxicology Program. NTP monograph on the systematic review of long-term neurological effects following acute exposure to sarin. NTP monograph. 2019 Jun [Epub ahead of print]. [ AbstractNational Toxicology Program. NTP monograph on the systematic review of long-term neurological effects following acute exposure to sarin. NTP monograph. 2019 Jun ]
- National Toxicology Program. NTP monograph on the systematic review of occupational exposure to cancer chemotherapy agents and adverse health outcomes. NTP monograph. 2019 Mar [Epub ahead of print]. [ AbstractNational Toxicology Program. NTP monograph on the systematic review of occupational exposure to cancer chemotherapy agents and adverse health outcomes. NTP monograph. 2019 Mar ]