2022
- Polymerase delta proofreading ensures fidelity during DNA replication – February
- 2021 Papers of the Year – January
- AEG12 inhibits mosquito-borne flavivirus by disrupting viral envelope
- When DNA repair goes awry
2021
- When DNA repair goes awry – October
- Trainee expands research and writing skills, transitions to grad school – August
- Remembering Sam Wilson, innovative scientist and NIEHS leader – June
- A novel approach generates high-resolution images of proteins – June
- Snapshots reveal how damaged nucleotides elude DNA repair safeguards – June
- AEG12 inhibits mosquito-borne flavivirus by disrupting viral envelope – May
- Insect study may lead to treatments for life-threatening viruses – April
- Cutting DNA is risky business – April
- Scott Williams wins outstanding science award for structural biology work – April
- DNA ligase 1 mutations offer clues to LIG1 syndrome – April
- Even skin shielded from sun shows DNA changes from UV light – February
- 2020 Papers of the Year – January
- Ubiquitin regulates removal of TOP2 DNA-protein crosslinks via TDP2
- New tool links faulty mtDNA replication to aging and disease
2020
- Polymerase mu provides scaffold for single- and double-strand breaks – December
- To study cancer’s origins, start with normal cells – December
- DNA Repair special issue honors renowned expert Sam Wilson – December
- Double-strand DNA breaks repaired by protein called polymerase mu – November
- Scientific Journeys: From researcher to role model – November
- Developmental mitochondrial inhibition causes dysfunction later in life – November
- New tool links faulty mtDNA replication to aging and disease – November
- Loss of APE2 is a key vulnerability in BRCA1/2 deficient cancer cells – August
- Ubiquitin regulates removal of TOP2 DNA-protein crosslinks via TDP2 – July
- DNA repair discovery holds promise for precision cancer therapy – July
- Scientific Journeys: From college lacrosse to X-ray crystallography – June
- NIEHS scientists join the fight against COVID-19 – May
- NIEHS cryo-EM resources support fight against novel coronavirus – April
- Robert London named NIH Scientist Emeritus – February
- Two methods ensure use of correct and undamaged DNA nucleotides – February
- 2019 Papers of the year - New roles for Pol delta in DNA replication – January
- From science to innovation — 2019 tech breakthroughs – January
- Cryo-EM enhances field of structural biology, experts say – January
- TLR8 SNP and p53-dependent immune responses to respiratory virus – January
2019
- Rubella virus, some cancers mutated via same mechanism - December
- Double-strand break repairs may lead to cancerous mutational clusters - December
- New roles for Pol delta in DNA replication - November
- Symposium honors distinguished NIEHS researcher - October
- Pol Mu allows insertion of mutagenic damage during repair - October
- Molecular sensor scouts DNA damage, supervises repair - September
- NIEHS fellow starts new position at Mayo Clinic - September
- Aging and cell stress harm DNA in similar ways - July
- Robert London celebrates upcoming retirement with symposium - July
- Oxidative stress causes distinct mutational signatures - July
- Pol B maintains its fidelity in the presence of modified cytosines - May
- Repair protein uses filaments to bridge broken DNA - April
- Pol epsilon catalytic domains necessary for error-free DNA replication - April
- Pol beta side chain residue prevents insertion of Fapy-dGTP damage - March
- 2018 Papers of the Year - Tumor suppressor p53 has broad role in homeostasis - January
- Accommodation of mismatched base pairing by DNA polymerase mu - January
2018
- DNA damage and mutations across the genome - October
- Tumor suppressor p53 has broad role in homeostasis - October
- Characterizing the structure of substrate-bound DNA ligase IV - September
- The role of aprataxin in a rare neurodegenerative disorder - September
- DNA polymerase beta substrate binding and catalysis - August
- Mechanism behind rare ataxia disease found by NIEHS scientists - August
2017
- Observing DNA polymerase mu repair DNA breaks - November
- Pol mu remains unchanged during NHEJ - November
- ZATT reverses DNA-protein crosslinks during chemotherapy - November
- ZATT protein reverses DNA damage from cancer treatment - November
- DNA Damage Caused by Cancer Treatment Reversed by ZATT Protein - October
- The technology won a Nobel Prize. Now Duke and UNC are getting into the game - October
- EMGS conference features NIEHS scientists in key roles - October
- Adjustable DNA pol beta catalyzes an efficient reverse reaction - October
- Las1 coordinates with Grc3 to cleave RNA - September
- NIEHS trainee Sara Andres transitions to academia - September
- NIEHS visiting fellow wins EMGS Young Scientist Award - August
- Crystal structure solved for ribosomal assembly factor Nsa1/WDR74 - July
- NIEHS Team Reports How Oxidative Stress Kills Cells - May
- Science at GISBL retreat involves talks, posters, and cookies - May
- Pol Beta uses lyase domain to search for DNA damage - April
- A third magnesium ion involved in DNA Pol Beta catalysis - April
- Key Step Discovered in DNA Damage from Oxidative Stress - March
- NIEHS Team Reports How Oxidative Stress Kills Cells - March
- Zinc finger domain critical to DNA repair - March
- DNA polymerase beta contains a nuclear localization signal - March
- Oxidized nucleotides block DNA repair - March
- Mutation signatures point to cancer causes, says Sir Michael Stratton - February
- New technique measures genomic mutations - February
- Nobel Laureate gives NIEHS Distinguished Lecture - January
- Dust mite allergens are more stable and abundant - January
2016
- Top scientists recognized with NIEHS Science Days awards - December
- NIEHS scientists play key roles in genetics meeting - December
- NIH recognizes 12 champions of environmental health research - November
- Dust mite proteins that cause allergies are more stable, more abundant - November
- Tenure means commitment to the future for two NIEHS scientists - September
- Scientists find susceptibility link to neurodegenerative diseases - July
- Tdp2 mediates anticancer drug resistance by processing damaged DNA - June
- Analysis of bisphenol A and potassium bromate exposure on mouse embryonic fibroblasts - June
- Mechanism may protect against neurodegenerative disease - May
- X-ray structure characterizes disease-causing factor in Streptococcus pyogenes - May
- Enzyme’s role in genome integrity discovered - February
- Fellows give small talks on the big picture of research - February
- 2015 Papers of the Year - January
2015
- Lab retreat links NIEHS researchers, alumni, and collaborators - November
- Fellows turn training into faculty positions - November
- NIEHS sheds light on main cause of mutations in certain cancers - September
- NIEHS fellows stand out in 2016 FARE competition - August
- Wilson’s mentoring award celebrated - August
- Andres awarded New Investigator Best Paper - June
- NIEHS researchers determine new function for DNA repair protein - February
- NIEHS scientists determine how environment contributes to several human diseases - January
2014
- In 2014, Science Days are bigger than ever - December
- Seventeen trainees join FARE winners’ circle - July
- Molecular genetics groups break for annual retreat - June
- Kunkel elected to American Academy of Arts and Sciences - June
2013
- Annual LSB retreat caps another successful year - October/November
2012
GISBL Retreat Articles
- Annual LSB retreat caps another successful year - October/November 2013
- Molecular genetics groups break for annual retreat - June 2014
- Lab retreat links NIEHS researchers, alumni, and collaborators - November 2015
TAC Articles
- DNA glycosylases in action - the search for damaged bases - September 2013
- Inhibitors of DNA topoisomerase and its repair enzymes in cancer treatment - September 2013
- Penn State professor explores consequences of non-regulated mitochondrial transcription - October/November 2013
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