2022

• Polymerase delta proofreading ensures fidelity during DNA replication – February
• 2021 Papers of the Year – January
  • AEG12 inhibits mosquito-borne flavivirus by disrupting viral envelope
  • When DNA repair goes awry

2021

• When DNA repair goes awry – October
• Trainee expands research and writing skills, transitions to grad school – August
• Remembering Sam Wilson, innovative scientist and NIEHS leader – June
• A novel approach generates high-resolution images of proteins – June
• Snapshots reveal how damaged nucleotides elude DNA repair safeguards – June
• AEG12 inhibits mosquito-borne flavivirus by disrupting viral envelope – May
• Insect study may lead to treatments for life-threatening viruses – April
• Cutting DNA is risky business – April
• Scott Williams wins outstanding science award for structural biology work – April
• DNA ligase 1 mutations offer clues to LIG1 syndrome – April
• Even skin shielded from sun shows DNA changes from UV light – February
• 2020 Papers of the Year – January
  • Ubiquitin regulates removal of TOP2 DNA-protein crosslinks via TDP2
  • New tool links faulty mtDNA replication to aging and disease

2020

• Polymerase mu provides scaffold for single- and double-strand breaks – December
• To study cancer’s origins, start with normal cells – December
• DNA Repair special issue honors renowned expert Sam Wilson – December
• Double-strand DNA breaks repaired by protein called polymerase mu – November
• Scientific Journeys: From researcher to role model – November
• Developmental mitochondrial inhibition causes dysfunction later in life – November
• New tool links faulty mtDNA replication to aging and disease – November
• Loss of APE2 is a key vulnerability in BRCA1/2 deficient cancer cells – August
• Ubiquitin regulates removal of TOP2 DNA-protein crosslinks via TDP2 – July
• DNA repair discovery holds promise for precision cancer therapy – July
• Scientific Journeys: From college lacrosse to X-ray crystallography – June
• NIEHS scientists join the fight against COVID-19 – May
• NIEHS cryo-EM resources support fight against novel coronavirus – April
• Robert London named NIH Scientist Emeritus – February
• Two methods ensure use of correct and undamaged DNA nucleotides – February
• 2019 Papers of the year - New roles for Pol delta in DNA replication – January
• From science to innovation — 2019 tech breakthroughs – January
• Cryo-EM enhances field of structural biology, experts say – January
• TLR8 SNP and p53-dependent immune responses to respiratory virus – January