Paul Wade, Ph.D.
Paul Wade, Ph.D.
Chief, Epigenetics & Stem Cell Biology Laboratory and Principal Investigator
Tel 984-287-4133
Fax 919-541-0146
[email protected]
P.O. Box 12233
Mail Drop D4-04
Durham, NC 27709
Traci Hall, Ph.D.
Traci Hall, Ph.D.
Deputy Chief and Principal Investigator
Tel 984-287-3556
Fax 301-480-3055
[email protected]
P.O. Box 12233
Mail Drop F3-05
Durham, NC 27709

Research Summary

The Epigenetics and Stem Cell Biology Laboratory investigates fundamental mechanisms by which epigenetics — non-genetic modulation and alterations — influences chromatin architecture, transcription and gene expression in normal, cancer and embryonic stem cells and provides insights into biological processes that modulate the effects of environmental exposures. It also focuses on the molecular basis of self-renewal and pluripotency in embryonic stem (ES) cells and induced pluripotency stem (iPS) cells, as well as gene regulatory pathways using genomic, molecular, biochemical, computational and structural approaches.

In addition to the cutting edge hypothesis driven research of its investigators the laboratory provides leadership and support to the NIEHS in areas of genomics, epigenomics, mass spectrometry, and bioinformatics analyses. These endeavors build and research strengths established in the prior Laboratory of Molecular Carcinogenesis and extend the scope of the research beyond cancer to examine a broad range of environmental impacts on human health and development.

Scientific Support Staff

Derrick L. Raynor
Administrative Technician
Tel 984-287-4006
[email protected]