Local scientists interested in receiving training from the NIEHS Cryo-Electron Microscopy Core Facility must contact Mario Borgnia.
The Molecular Microscopy Consortium allows scientists from NIEHS, the University of North Carolina at Chapel Hill, and Duke University to use single particle cryo-electron microscopy and other tools in molecular microscopy to solve macromolecular structures at the atomic level. Cryo-EM requires smaller quantities of material than other structural methods and is especially suitable for the study of hard to crystallize large macromolecular complexes and membrane proteins.
This video shows how the NIEHS Cryo-EM Facility generates 3D images of large proteins. (3:53)
Types of projects we do:
- Data collection
- Specimen preparation
- Experimental design advice and training
- Image processing and interpretation
Mario J. Borgnia, Ph.D.
Director, Molecular Microscopy Consortium
111 Tw Alexander Dr
Research Triangle Park, NC 27709
Jonathan Bouvette, Ph.D.
Fellow — Visiting
P.O. Box 12233Mail Drop MR-02Durham, N.C. 27709
Allen L. Hsu
P.O. Box 12233Mail Drop MR-01Durham, N.C. 27709