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Your Environment. Your Health.

Translational Toxicology Division Strategic Planning Framework

Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Visit the NTP Website

The Division of Translational Toxicology (DTT) conducts innovative toxicology research that aligns with real-world public health needs and translates scientific evidence into knowledge that can inform individual and public decision making.

The DTT research portfolio is organized and executed using a strategic framework based on three objectives:

  • Accelerate our progress toward becoming a more predictive, precise, and preventive science through the deliberate application of a translational toxicology pipeline of capabilities.
  • Provide an evidence-based approach to identifying and understanding potential environmental contributors to contemporary and common diseases.
  • Improve our ability to conduct and communicate substance-based hazard evaluations that are more translational, innovative, and responsive.

DTT scientists aim to achieve those goals through the program areas below. Explore each program and learn how the researchers are tackling issues ranging from cardiovascular health and developmental neurotoxicity to occupational exposures and scientific cyberinfrastructure.

Exposure-based Research Programs, test tubes and flask, smokestacks, and household cleaners

Exposure-based Research Programs

This strategic area of focus aligns with DTT’s intent to solve contemporary public health problems related to environmental exposures and includes the following program areas:

  • Combined Exposures and Mixtures
  • Consumer Products and Therapeutics
  • Occupational and Inhalation Exposure
Health Effects Innovation Programs, heart connected to a monitor, brain, and cancer ribbon

Health Effects Innovation Programs

This strategic area of focus aligns with DTT’s intent to develop disease-focused environmental toxicology and includes the following program areas:

  • Carcinogenicity Health Effects Innovation
  • Cardiovascular Health Effects Innovation
  • Developmental Neurotoxicity Health Effects Innovation
Responsive Research Programs, beaker showcasing green chemistry and toxic waste drum sinking

Responsive Research Programs

This strategic area of focus aligns with DTT’s intent to respond proactively to public health concerns related to novel environmental exposures and includes the following program areas:

  • Emerging Contaminants and Issues of Concern
  • Safe and Sustainable Alternatives
Responsive Research Programs, settings and laptop icons

Strengthening Capabilities Programs

This strategic area of focus aligns with DTT’s intent to enhance toxicology toward becoming a more predictive science through the development and application of new technologies and includes the following program areas:

  • Novel Tools and Approaches
  • Scientific Cyberinfrastructure
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