May 24 - 25, 2022 • 11:00 a.m. - 4:00 p.m. EDT
May 26, 2022 • 11:00 a.m. - 4:30 p.m. EDT
- Glossary Terms and References (199KB)
- Executive Summary (160KB)
- Workshop Report (417KB)
This jointly supported NIEHS/NHGRI virtual workshop was convened to determine the current capabilities, needs, and prospects for comprehensive characterization and understanding of the true diversity of all RNAs and their modifications at a chemical and structural level in relation to normal and disease states.
- To explore the need for “RNomics” in genomics.
- To identify what technologies are needed to sequence full-length RNAs directly capturing molecular diversity and cellular context.
- To determine what infrastructure, bioinformatics, and other resources are needed to support technology development, utilization, and validation.
- To consider the steps needed to facilitate rapid adoption of these technologies by the wider scientific community.
Workshop Topics and Recordings
Click on the session title to view recording.
- Opening Remarks
- Session 1: Setting the Stage
- Session 2: Impact on RNA Structure and Biological Roles
- Breakout 2A: Association With RBPs
- Breakout 2B: Impact of Cellular Stress
- Breakout 2C: Influences of Modifications on RNA Structure and Dynamics
- Session 3: RNomics Applications from Research to Clinic
- Session 4: Technologies for Direct Sequencing
- Breakout 4A: Technologies on the Horizon
- Breakout 4B: Leveraging Existing Technologies – Opportunities for Further Innovation
- Breakout 4C: Unmet Challenges and Needs
- Session 5: Infrastructure, Bioinformatics, and Critical Resources: What is Needed?
- Breakout 5A: Infrastructure and Bioinformatics
- Breakout 5B: Critical Computational Resources
- Breakout 5C: Critical Biological Resources
- Session 6: Facilitating Technology Dissemination and Adoption
- Wrap-up Session
For questions on the workshop content, please contact Fred Tyson, 984-287-3334.