Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
These reports provide the findings and conclusions of studies of AIDS therapeutics conducted in rodents. The studies evaluated single therapeutic agents or combination therapies for effects on reproduction, general health, and the development of offspring.
| Abstract | Full Text | Report Title | Year | Type |
|---|---|---|---|---|
| AIDS-09 | AIDS-09 Full Report (5MB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Studies of 3'-Azido-3'-deoxythymidine (AZT) and Clarithromycin Combinations (CASRNs 30516-87-1 and 81103-11-9) Administered by Gavage to Swiss (CD-1®) Mice | 2003 | AIDS Therapeutics |
| AIDS-08 | AIDS-08 Full Report (2MB) | NIEHS Technical Report on the 13-Week Toxicity Study of 3'-Azido-3'-deoxythymidine (AZT) and Isoniazid Combinations (CASRNs 30516-87-1 and 54-85-3) Administered by Gavage to B6C3F1 Mice | 2002 | AIDS Therapeutics |
| AIDS-07 | AIDS-07 Full Report (4MB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Study of 3'-Azido-3'-deoxythymidine (AZT) and Pyrazinamide Combinations (CASRNs 30516-87-1 and 98-96-4) Administered by Gavage to Swiss (CD-1®) Mice | 2002 | AIDS Therapeutics |
| AIDS-06 | AIDS-06 Full Report (5MB) | NIEHS Technical Report on the Subchronic Toxicity Study of 3'-Azido-3'-dioxythymidine (AZT) and Rifampicin Combinations (CASRNs 30516-87-1 and 13292-46-1) Administered by Gavage to B6C3F1 Mice | 2001 | AIDS Therapeutics |
| AIDS-05 | AIDS-05 Full Report (2MB) | NIEHS Technical Report on the Subchronic Toxicity Study of 3'-Azido-3'-dioxythymidine (AZT) and Pyrazinamide Combinations (CASRNs 30516-87-1 and 98-96-4) Administered by Gavage to B6C3F1 Mice | 1999 | AIDS Therapeutics |
| AIDS-04 | AIDS-04 Full Report (6MB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Study of 3'-Azido-3'-deoxythymidine (AZT) and Rifabutin Combinations (CASRNs 30516-87-1 and 72559-06-9) Administered by Gavage to Swiss (CD-1®) Mice | 2000 | AIDS Therapeutics |
| AIDS-03 | AIDS-03 Full Report (2MB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Studies of 3'-Azido-3'-dioxythymidine (AZT) and Isoniazid Combinations (CASRNs 30516-87-1 and 54-85-3) Administered by Gavage to Swiss (CD-1®) Mice | 1999 | AIDS Therapeutics |
| AIDS-02 | AIDS-02 Full Report (5MB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Studies of 3'-Azido-3'-dioxythymidine (AZT), Trimethoprim (TMP)/ Sulfamethoxazole (SMX), and Folinic Acid Combinations Administered by Gavage to Swiss (CD-1®) Mice | 1998 | AIDS Therapeutics |
| AIDS-01 | AIDS-01 Full Report (888KB) | NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Studies of Pyrazinamide (CASRN 98-96-4) Administered by Gavage to Swiss (CD-1®) Mice | 1997 | AIDS Therapeutics |