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Your Environment. Your Health.

Circular FSA - Software Usage Agreement and Download

Developed by:

Shyamal D. Peddada
National Institute of Environmental Health Sciences
Biostatistics Branch

Programmed by Dr. Miguel T. Fernandez, University of Valladolid, Valladolid, Spain


Suppose A and B are two species of organisms where { A1,A2,...,AG } is a set of cell cycle genes of species A and { B1,B2,...,BG } is the set of corresponding orthologs of species B. Suppose the phase angles of the set {A1,A2,...,AG} satisfy the following relative order around the unit circle: A1 < A2 < A3 < ... < AG < A1, where the notation A1 < A2 refers to "gene A2 follows gene A1 in its time to peak expression", then the program tests whether the orthologs {B1,B2,...,BG} satisfy the same relative order as the genes { A1,A2,...,AG }, i.e., it tests the null hypothesis B1 < B2 < B3 < ... < BG < B1 against the alternative that the order is not satisfied. If the null hypothesis is rejected then identifies the subset of g genes { BS1,BS2,...,BSg } which have the same relative order of time to peak expression as the corresponding subset { AS1,AS2,...,ASg } by eliminating genes which are out of order.

Software info:

The software is applicable to any version of SAS 9. or better. Details on how to use is provided in the README.pdf file.



Shyamal D. Peddada, Ph.D.
Acting Branch Chief, Biostatistics & Computational Biology Branch and Principal Investigator
Tel (919) 541-1122
Fax (919) 541-4311