Nucleolar Integrity Group

  1. Blaha*, Stanley RE*, Steitz TA. (2009) Formation of the first peptide bond: The structure of EF-P bound to the 70S ribosome. Science. 325(5943):966-970. *Both authors contributed equally [Abstract Blaha*, Stanley RE*, Steitz TA. (2009) Formation of the first peptide bond: The structure of EF-P bound to the 70S ribosome. Science. 325(5943):966-970. *Both authors contributed equally]
  2. Stanley RE*, Blaha G*, Grodzicki RL, Strickler MD, Steitz TA. (2010) The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol. 17(3):289-293. *Both authors contributed equally [Abstract Stanley RE*, Blaha G*, Grodzicki RL, Strickler MD, Steitz TA. (2010) The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol. 17(3):289-293. *Both authors contributed equally]
  3. Ragusa MJ*, Stanley RE*, Hurley JH. (2012) Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell. 151(7):1501-1512. *Both authors contributed equally [Abstract Ragusa MJ*, Stanley RE*, Hurley JH. (2012) Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell. 151(7):1501-1512. *Both authors contributed equally]
  4. Jao CC, Ragusa MJ, Stanley RE, Hurley JH. (2013) A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc Natl Acad Sci U S A. 110(14):5486-91. [Abstract Jao CC, Ragusa MJ, Stanley RE, Hurley JH. (2013) A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc Natl Acad Sci U S A. 110(14):5486-91.]
  5. Stanley RE, Ragusa MJ, Hurley JH. (2014) The beginning of the end: How scaffolds and coalescing vesicles nucleate autophagosome biogenesis. Trends Cell Biol. 24(1):73-81. [Abstract Stanley RE, Ragusa MJ, Hurley JH. (2014) The beginning of the end: How scaffolds and coalescing vesicles nucleate autophagosome biogenesis. Trends Cell Biol. 24(1):73-81.]
  6. Romes, EM, Sobhany, M, Stanley, RE. The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin. The Journal of biological chemistry 2016 291(2):882-893. [Abstract Romes, EM, Sobhany, M, Stanley, RE. The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin. The Journal of biological chemistry 2016 291(2):882-893.]
  7. Lo YH, Romes EM, Pillon MC, Sobhany M, Stanley* RE. (2017) Structural Analysis Reveals the Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with the AAA-ATPase Rix7/NVL2. Structure. 25(5):762-772 PMID: 28416111 [Abstract Lo YH, Romes EM, Pillon MC, Sobhany M, Stanley* RE. (2017) Structural Analysis Reveals the Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with the AAA-ATPase Rix7/NVL2. Structure. 25(5):762-772 PMID: 28416111] 
  8. Pillon MC, Sobhany M, Borngia MJ, Williams JG, and Stanley* RE. (2017) Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage. Proc Natl Acad Sci. PNAS Early Edition doi: 10.1073/pnas.1703133114 PMID: 28652339 [Abstract Pillon MC, Sobhany M, Borngia MJ, Williams JG, and Stanley* RE. (2017) Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage. Proc Natl Acad Sci. PNAS Early Edition doi: 10.1073/pnas.1703133114 PMID: 28652339]
  9. Pillon MC, Stanley RE. Nuclease integrated kinase super assemblies (NiKs) and their role in RNA processing. Current Genetics 2018 64(1):183-190. [Abstract Pillon MC, Stanley RE. Nuclease integrated kinase super assemblies (NiKs) and their role in RNA processing. Current Genetics 2018 64(1):183-190.]
  10. Lo YH, Sobhany M, Hsu AL, Ford BL, Krahn JM, Borgnia MJ, Stanley RE. Cryo-EM Structure of the Essential Ribosome Assembly AAA-ATPase Rix7. Nature Communications 2019 10(1):513. [Abstract Lo YH, Sobhany M, Hsu AL, Ford BL, Krahn JM, Borgnia MJ, Stanley RE. Cryo-EM Structure of the Essential Ribosome Assembly AAA-ATPase Rix7. Nature Communications 2019 10(1):513.]
  11. Gordon J, Pillon MC, Stanley RE. 2019. Nol9 Is a Spatial Regulator for the Human ITS2 Pre-rRNA Endonuclease-Kinase Complex. Journal of Molecular Biology 431(19):3771-3786. [Abstract Gordon J, Pillon MC, Stanley RE. 2019. Nol9 Is a Spatial Regulator for the Human ITS2 Pre-rRNA Endonuclease-Kinase Complex. Journal of Molecular Biology 431(19):3771-3786.]
  12. Pillon MC, Lo YH, Stanley RE. 2019. IT'S 2 for the price of 1: Multifaceted ITS2 Processing Machines in RNA and DNA Maintenance. DNA Repair 81:102653. [Abstract Pillon MC, Lo YH, Stanley RE. 2019. IT'S 2 for the price of 1: Multifaceted ITS2 Processing Machines in RNA and DNA Maintenance. DNA Repair 81:102653.]
  13. Pillon MC, Hsu AL, Krahn JM, Williams JG, Goslen KH, Sobhany M, Borgnia MJ, Stanley RE. 2019. Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex. Nat Struct Mol Bio 26(9):830-839. [Abstract Pillon MC, Hsu AL, Krahn JM, Williams JG, Goslen KH, Sobhany M, Borgnia MJ, Stanley RE. 2019. Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex. Nat Struct Mol Bio 26(9):830-839.]
  14. Prattes M, Lo YH, Bergler H, Stanley RE. 2019. Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis. Biomolecules doi: 10.3390/biom9110715 [Online 7 November 2019]. [Abstract Prattes M, Lo YH, Bergler H, Stanley RE. 2019. Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis. Biomolecules doi: 10.3390/biom9110715 [Online 7 November 2019].]
  15. Pillon MC, Goslen KH, J Gordon, MJ Wells, Williams JG, Stanley RE. 2020. It takes two (Las1 HEPN endoribonuclease Domains) to cut RNA correctly. J Biol Chem; doi: 10.1074/jbc.RA119.011193 [Online 27 March 2020]. [Abstract Pillon MC, Goslen KH, J Gordon, MJ Wells, Williams JG, Stanley RE. 2020. It takes two (Las1 HEPN endoribonuclease Domains) to cut RNA correctly. J Biol Chem; doi: 10.1074/jbc.RA119.011193 [Online 27 March 2020].]
  16. Pillon MC, Stanley RE. 2020. Nonradioactive assay to measure polynucleotide phosphorylation of small nucleotide substrates. J Vis Exp; doi: 10.3791/61258 [Online 8 May 2020]. [Abstract Pillon MC, Stanley RE. 2020. Nonradioactive assay to measure polynucleotide phosphorylation of small nucleotide substrates. J Vis Exp; doi: 10.3791/61258 [Online 8 May 2020].]
  17. Hayne CK, Schmidt CA, Haque MI, Matera AG, Stanley RE. 2020. Reconstitution of the human tRNA splicing endonuclease complex: Insight into the regulation of pre-tRNA cleavage. Nucleic Acids Res; doi: 10.1093/nar/gkaa438 [Online 1 June 2020]. [Abstract Hayne CK, Schmidt CA, Haque MI, Matera AG, Stanley RE. 2020. Reconstitution of the human tRNA splicing endonuclease complex: Insight into the regulation of pre-tRNA cleavage. Nucleic Acids Res; doi: 10.1093/nar/gkaa438 [Online 1 June 2020].]
  18. Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. 2020. Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break. Nat Commun; doi: 10.1038/s41467-020-18506-5 [Online 22 September 2020]. [Abstract Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. 2020. Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break. Nat Commun; doi: 10.1038/s41467-020-18506-5 [Online 22 September 2020].]
  19. Frazier MN, Pillon MC, Kocaman S, Gordon J, Stanley RE. 2020. Structural overview of macromolecular machines involved in ribosome biogenesis. Curr Opin Struct Biol 67:51-60. [Abstract Frazier MN, Pillon MC, Kocaman S, Gordon J, Stanley RE. 2020. Structural overview of macromolecular machines involved in ribosome biogenesis. Curr Opin Struct Biol 67:51-60.]
  20. Pillon MC, Gordon J, Frazier MN, Stanley RE. 2020. HEPN RNases - an emerging class of functionally distinct RNA processing and degradation enzymes. Crit Rev Biochem Mol Biol; doi: 10.1080/10409238.2020.1856769 [Online 22 December 2020]. [Abstract Pillon MC, Gordon J, Frazier MN, Stanley RE. 2020. HEPN RNases - an emerging class of functionally distinct RNA processing and degradation enzymes. Crit Rev Biochem Mol Biol; doi: 10.1080/10409238.2020.1856769 [Online 22 December 2020].]
  21. Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. 2021. Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics. Nat Commun; doi: 10.1038/s41467-020-20608-z [Online 27 January 2021]. [Abstract Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. 2021. Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics. Nat Commun; doi: 10.1038/s41467-020-20608-z [Online 27 January 2021].]
  22. Sobhany M, Stanley RE. 2021. Polysome Profiling without Gradient Makers or Fractionation Systems. J Vis Exp (172). [Abstract Sobhany M, Stanley RE. 2021. Polysome Profiling without Gradient Makers or Fractionation Systems. J Vis Exp (172).]
  23. Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE. 2021. Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res; doi: 10.1093/nar/gkab719 [Online 17 August 2021]. [Abstract Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE. 2021. Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res; doi: 10.1093/nar/gkab719 [Online 17 August 2021].]