NTP Logo

Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Genetically-defined Rodents

CMPB Lab Animal Medicine - An image of mouse in a scientist's hands

The National Toxicology Program (NTP) Laboratory Animal Medicine Group oversees, directs, and manages the use of laboratory animal models for the NTP:

  • Assisting in the selection and provision of disease-free genetically defined rodent models
  • Monitoring animal care and use in NTP studies
  • Establishing policies and guidelines, and ensuring standards of laboratory animal management for NTP studies
  • Advising the NTP on animal care and animal welfare issues
  • Conducting site visits at all NTP testing laboratories and ensuring that Laboratory Animals Medicine specifications are followed
  • Providing guidelines and review of vendors/suppliers

NIEHS/NTP Laboratory Animal Medicine Training Program

The Group offers training in Laboratory Animal Medicine that allows post-doctoral fellows to participate in NTP and NIEHS laboratory animal medicine programs.  NTP Laboratory Animal Medicine fellows interact with board certified American College of Laboratory Animal Medicine (ACLAM) veterinarians located in Research Triangle Park, North Carolina, and surrounding areas. The fellows train in a variety of laboratory animal science settings and have the opportunity to attend local and national training activities and scientific meetings, as well as to engage in collaborative research with NTP and NIEHS scientists. NIEHS, University of North Carolina Chapel Hill, and other academic institutes in the local area provide hands-on clinical experience.  Fellows participate in didactic sessions held at NIEHS with other local laboratory animal fellows/residents.

Angela King-Herbert, D.V.M., DACLAM, leads the NTP Laboratory Animal Medicine Group within the Cellular & Molecular Pathology Branch. She earned her D.V.M. at Tuskegee University School of Veterinary Medicine and completed training in Laboratory Animal Medicine at North Carolina State University College of Veterinary Medicine.  King-Herbert served as Attending Veterinarian and Manager of Animal Biology at RJ Reynolds before joining NIEHS in 2004. She is a Diplomat in the American College of Laboratory Animal Medicine (DACLAM).