Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Report on Carcinogens
Matthew (Matt) Urich, Ph.D., is a staff scientist in the Integrative Health Assessments Branch of the Division of Translational Toxicology (DTT), at the National Institute of Environmental Health Sciences (NIEHS). He conducts hazard evaluations and provides toxicological expertise for the Report on Carcinogens (RoC), a congressionally mandated report that identifies substances or exposure circumstances that may pose a hazard to human health by virtue of their carcinogenicity.
Before joining DTT, Urich worked at the U.S. Environmental Protection Agency (EPA), where he led and contributed to human health hazard and risk assessments and supported methodological developments across multiple EPA offices, including the Office of Chemical Safety and Pollution Prevention, Office of Research and Development, and Office of Air and Radiation. His work addressed pesticides, antimicrobials, industrial chemicals, polymers, metals and metal complexes, per- and polyfluoroalkyl substances (PFAS), and hazardous air pollutants, with emphasis on incorporating mechanistic and computational approaches into regulatory assessment frameworks.
Urich received his Ph.D. in toxicology from the University of Georgia’s Interdisciplinary Toxicology Program, where his dissertation research investigated adverse outcome pathways associated with endocrine disrupting chemicals. He completed a postdoctoral fellowship at EPA’s Center for Environmental Measurement and Modelling, conducting metabolomics analyses and developing analytical chemistry methods for detecting and quantifying PFAS. His current research interests center on the integration of multiple chemical and toxicological data streams, including mechanistic and computational toxicology, in vitro and in silico new approach methodologies (NAMs), toxicogenomics, and read-across approaches, as well as traditional in vivo and in vitro toxicology, using systematic review and weight-of-evidence methods to identify and characterize environmental hazards to human health.