Calcium Signaling in Health & Disease Group

1. Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels. Function 2(5):zqab036. [Abstract Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels. Function 2(5):zqab036.] [Full Text Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels. Function 2(5):zqab036.]
2. Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry. Proc Natl Acad Sci USA. 118(19):e2012908118. [Abstract Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry. Proc Natl Acad Sci USA. 118(19):e2012908118.]
3. Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca²⁺-dependent transcription factors by STIM1-Orai1 channel clusters. Nature Communications. 10(1):2516. [Abstract Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca²⁺-dependent transcription factors by STIM1-Orai1 channel clusters. Nature Communications. 10(1):2516.]
4. Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca²⁺ channels and mast cell migration through PAR4 receptors. Molecular Cell. 70(2):228-241.e5. [Abstract Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca²⁺ channels and mast cell migration through PAR4 receptors. Molecular Cell. 70(2):228-241.e5.]
5. Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na⁺ Ca²⁺ exchanger generates Ca2+ oscillations within mitochondria. Nature Communications. 9(1):156. [Abstract Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na⁺ Ca²⁺ exchanger generates Ca2+ oscillations within mitochondria. Nature Communications. 9(1):156.].
6. Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca²⁺ signals. Molecular Cell. 64(4):746-759. [Abstract Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca²⁺ signals. Molecular Cell. 64(4):746-759.]
7. Kar P, Parekh AB. 2015. Distinct spatial Ca²⁺ signatures selectively activate different NFAT transcription factor isoforms. Molecular Cell. 58(2):232-243. [Abstract Kar P, Parekh AB. 2015. Distinct spatial Ca²⁺ signatures selectively activate different NFAT transcription factor isoforms. Molecular Cell. 58(2):232-243.]
8. Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca²⁺-dependent gene expression. Nature. 482(7383):111-115. [Abstract Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca²⁺-dependent gene expression. Nature. 482(7383):111-115.]