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Your Environment. Your Health.

Selected Publications

Calcium Signaling in Health & Disease Group

    1. Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry. Proc Natl Acad Sci USA. 118(19):e2012908118. [Abstract Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry. Proc Natl Acad Sci USA. 118(19):e2012908118.] 
    2. Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters. Nature Communications. 10(1):2516. [Abstract Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters. Nature Communications. 10(1):2516.]
    3. Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca2+ channels and mast cell migration through PAR4 receptors. Molecular Cell. 70(2):228-241.e5. [Abstract Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca2+ channels and mast cell migration through PAR4 receptors. Molecular Cell. 70(2):228-241.e5.]
    4. Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria. Nature Communications. 9(1):156. [Abstract Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria. Nature Communications. 9(1):156.].
    5. Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca2+ signals. Molecular Cell. 64(4):746-759. [Abstract Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca2+ signals. Molecular Cell. 64(4):746-759.]
    6. Kar P, Parekh AB. 2015. Distinct spatial Ca2+ signatures selectively activate different NFAT transcription factor isoforms. Molecular Cell. 58(2):232-243. [Abstract Kar P, Parekh AB. 2015. Distinct spatial Ca2+ signatures selectively activate different NFAT transcription factor isoforms. Molecular Cell. 58(2):232-243.]
    7. Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression. Nature. 482(7383):111-115. [Abstract Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression. Nature. 482(7383):111-115.]
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