Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Mechanistic Toxicology Branch
Danielle Freeborn is a Biologist in the NIEHS Division of Translational Toxicology (DTT) in the Mechanistic Toxicology Branch. She obtained her B.S. in Biology with a minor in Chemistry from the University of North Carolina at Chapel Hill. Danielle specializes in PCR and cell culture. Prior to working at the NIEHS, Danielle worked at the EPA in the NeuroEndocrine Toxicology Branch of the Office of Research and Development.
Recent Publications
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Jackson T, Alewel D, Vance S, Gavett S, Schladweiler M, Evansky P, Monsees M, Freeborn D, Martin J, George I, Warren N, Grindstaff R, Kodavanti P, Crabbs T, Fisher R, Brown Q, Ganta C, Sills R, Herbert R, Kodavanti U. Respiratory health outcomes following co-exposure to subchronic high temperature, episodic wildfire smoke exposure, and high-cholesterol diet.
Inhalation toxicology.
2026 Sep;38(8):433-454.
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AbstractJackson T, Alewel D, Vance S, Gavett S, Schladweiler M, Evansky P, Monsees M, Freeborn D, Martin J, George I, Warren N, Grindstaff R, Kodavanti P, Crabbs T, Fisher R, Brown Q, Ganta C, Sills R, Herbert R, Kodavanti U. Respiratory health outcomes following co-exposure to subchronic high temperature, episodic wildfire smoke exposure, and high-cholesterol diet. Inhalation toxicology. 2026 Sep
]
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Henriquez A, Snow S, Jackson T, House J, Alewel D, Schladweiler M, Valdez M, Freeborn D, Miller C, Grindstaff R, Kodavanti P, Kodavanti U. Social isolation exacerbates acute ozone inhalation induced pulmonary and systemic health outcomes.
Toxicology and applied pharmacology.
2022 Dec 15;457:116295.
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AbstractHenriquez A, Snow S, Jackson T, House J, Alewel D, Schladweiler M, Valdez M, Freeborn D, Miller C, Grindstaff R, Kodavanti P, Kodavanti U. Social isolation exacerbates acute ozone inhalation induced pulmonary and systemic health outcomes. Toxicology and applied pharmacology. 2022 Dec 15
]
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Miller C, Dye J, Henriquez A, Stewart E, Lavrich K, Carswell G, Ren H, Freeborn D, Snow S, Schladweiler M, Richards J, Kodavanti P, Fisher A, Chorley B, Kodavanti U. Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation.
Molecular metabolism.
2020 Dec;42:101094.
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AbstractMiller C, Dye J, Henriquez A, Stewart E, Lavrich K, Carswell G, Ren H, Freeborn D, Snow S, Schladweiler M, Richards J, Kodavanti P, Fisher A, Chorley B, Kodavanti U. Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation. Molecular metabolism. 2020 Dec
]
