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Your Environment. Your Health.

Selected Publications

Clinical Investigation of Host Defense Group

2020

  1. Madenspacher JH, Morrell ED, Gowdy KM, McDonald JG, Thompson BM, Muse GW, Martinez J, Thomas SY, Mikacenic C, Nick JA, Abraham E, Garantziotis S, Stapleton RD, Meacham JM, Thomassen MJ, Janssen WJ, Cook DN, Wurfel MM, Fessler MB. 2020. Cholesterol-25-hydroxylase promotes efferocytosis and resolution of lung inflammation. JCI Insight; doi: 10.1172/jci.insight.137189 [Online 28 April 2020]. [Abstract Madenspacher JH, Morrell ED, Gowdy KM, McDonald JG, Thompson BM, Muse GW, Martinez J, Thomas SY, Mikacenic C, Nick JA, Abraham E, Garantziotis S, Stapleton RD, Meacham JM, Thomassen MJ, Janssen WJ, Cook DN, Wurfel MM, Fessler MB. 2020. Cholesterol-25-hydroxylase promotes efferocytosis and resolution of lung inflammation. JCI Insight; doi: 10.1172/jci.insight.137189 [Online 28 April 2020].]

2019

  1. Ajayi T, Innes CL, Grimm SA, Wang X, Bell DA, McGrath JA, Schurman SH, Fessler MB. Crohn's Disease IRGM Risk Alleles are Associated with Altered Gene Expression in Human Tissues. American Journal of Physiology-Gastrointestinal and Liver Physiology 2019; 316(1):G95-G105. [Abstract Ajayi T, Innes CL, Grimm SA, Wang X, Bell DA, McGrath JA, Schurman SH, Fessler MB. Crohn's Disease IRGM Risk Alleles are Associated with Altered Gene Expression in Human Tissues. American Journal of Physiology-Gastrointestinal and Liver Physiology 2019; 316(1):G95-G105.]
  2. Madenspacher JH, Stapleton RD, Suratt BT, Dixon AE, Lih, FB, Lowe JM, Mould KJ, Janssen WJ, Morrell ED, Wurfel MM, Garantziotis S, Tomer KB, Fessler MB. Cholestenoic Acid Is a Prognostic Biomarker in Acute Respiratory Distress Syndrome. Journal of Allergy and Clinical Immunology 2019; 143(1):440-442. [Abstract Madenspacher JH, Stapleton RD, Suratt BT, Dixon AE, Lih, FB, Lowe JM, Mould KJ, Janssen WJ, Morrell ED, Wurfel MM, Garantziotis S, Tomer KB, Fessler MB. Cholestenoic Acid Is a Prognostic Biomarker in Acute Respiratory Distress Syndrome. Journal of Allergy and Clinical Immunology 2019; 143(1):440-442.]
  3. Aloor JJ, Azzam KM, Guardiola JJ, Gowdy KM, Madenspacher JH, Gabor KA, Mueller GA, Henderson MW, Draper DW, Merrick BA, Fessler MB. Leucine-Rich Repeats and Calponin Homology Containing 4 Regulates the Innate Immune Response. Journal of Biological Chemistry 2019;294(6):1997-2008. [Abstract Aloor JJ, Azzam KM, Guardiola JJ, Gowdy KM, Madenspacher JH, Gabor KA, Mueller GA, Henderson MW, Draper DW, Merrick BA, Fessler MB. Leucine-Rich Repeats and Calponin Homology Containing 4 Regulates the Innate Immune Response. Journal of Biological Chemistry 2019;294(6):1997-2008.]
  4. Kamal M, Aloor JJ, Fessler MB, Chowdhury SC. Cross-linking Proteomics Indicates Effects of Simvastatin on the TLR2 Interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade. Molecular and Cellular Proteomics 2019 Jun 20. pii: mcp.RA119.001377. [Abstract Kamal M, Aloor JJ, Fessler MB, Chowdhury SC. Cross-linking Proteomics Indicates Effects of Simvastatin on the TLR2 Interactome and Reveals ACTR1A as a Novel Regulator of the TLR2 Signal Cascade. Molecular and Cellular Proteomics 2019 Jun 20. pii: mcp.RA119.001377.]
  5. Chen P, Wang S, Janardhan KS, Zemans RL, Deng W, Karmaus P, Shen S, Sunday M, Que LG, Fessler MB, Zhong XP. Efficient CD4Cre-Mediated Conditional Kras Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis. Journal of Immunology 2019 Sep 1; 203(5):1208-17. [Abstract Chen P, Wang S, Janardhan KS, Zemans RL, Deng W, Karmaus P, Shen S, Sunday M, Que LG, Fessler MB, Zhong XP. Efficient CD4Cre-Mediated Conditional Kras Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis. Journal of Immunology 2019 Sep 1; 203(5):1208-17.]
  6. McGee C, Sample C, Kilburg-Basnyat B, Gabor K, Fessler MB, Gowdy KM. Influenza-mediated Lung Infection Models. Methods in Molecular Biology 2019; 1960:191-205. [Abstract McGee C, Sample C, Kilburg-Basnyat B, Gabor K, Fessler MB, Gowdy KM. Influenza-mediated Lung Infection Models. Methods in Molecular Biology 2019; 1960:191-205.]
  7. Fessler MB. Drugging the Mighty Neutrophil in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology 2019 Apr;60(4):382-383. [Abstract Fessler MB. Drugging the Mighty Neutrophil in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology 2019 Apr;60(4):382-383.]
  8. McPeek M, Malur A, Tokarz DA, Lertpiriyapong K, Gowdy KM, Murray G, Wingard CJ, Fessler MB, Barna BP, Thomassen MJ. 2019. Alveolar Macrophage ABCG1 Deficiency Promotes Pulmonary Granulomatous Inflammation. Am J Respir Cell Mol Biol; doi: 10.1165/rcmb.2018-0365OC [Online 8 March 2019]. [Abstract McPeek M, Malur A, Tokarz DA, Lertpiriyapong K, Gowdy KM, Murray G, Wingard CJ, Fessler MB, Barna BP, Thomassen MJ. 2019. Alveolar Macrophage ABCG1 Deficiency Promotes Pulmonary Granulomatous Inflammation. Am J Respir Cell Mol Biol; doi: 10.1165/rcmb.2018-0365OC [Online 8 March 2019].]

2018

  1. Kumar A, Triquigneaux M, Madenspacher J, Ranguelova K, Bang JJ, Fessler MB, Mason RP. Sulfite-Induced Protein Radical Formation in LPS Aerosol-Challenged Mice: Implications for Sulfite Sensitivity in Human Lung Disease. Redox Biology 2018; 15:327-334. [Abstract Kumar A, Triquigneaux M, Madenspacher J, Ranguelova K, Bang JJ, Fessler MB, Mason RP. Sulfite-Induced Protein Radical Formation in LPS Aerosol-Challenged Mice: Implications for Sulfite Sensitivity in Human Lung Disease. Redox Biology 2018; 15:327-334.]
  2. Kamal AHM, Fessler MB, Chowdhury SC. Comparative and Network-based Proteomic Analysis of Low Dose Ethanol- and Lipopolysaccharide-induced Macrophages. PLoS One 2018; 13(2):e0193104 [Abstract Kamal AHM, Fessler MB, Chowdhury SC. Comparative and Network-based Proteomic Analysis of Low Dose Ethanol- and Lipopolysaccharide-induced Macrophages. PLoS One 2018; 13(2):e0193104]
  3. Fessler MB. The Challenges and Promise of Targeting the Liver X Receptors for Treatment of Inflammatory Disease. Pharmacology and Therapeutics 2018; 181:1-12. [Abstract Fessler MB. The Challenges and Promise of Targeting the Liver X Receptors for Treatment of Inflammatory Disease. Pharmacology and Therapeutics 2018; 181:1-12.]

2017

  1. Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, Patel PS, Kearney JF, Taylor GA, Fessler MB. Irgm1 Coordinately Regulates Autoimmunity and Host Defense at Select Mucosal Surfaces. JCI Insight 2017 Aug 17;2(16). pii: 91914. [Abstract Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, Patel PS, Kearney JF, Taylor GA, Fessler MB. Irgm1 Coordinately Regulates Autoimmunity and Host Defense at Select Mucosal Surfaces. JCI Insight 2017 Aug 17;2(16). pii: 91914.]
  2. Henderson MW, Madenspacher JH, Whitehead GS, Thomas SY, Aloor JJ, Gowdy KM, Fessler MB. Effects of Orally Ingested Arsenic Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice. Environmental Health Perspectives 2017; Sep 28; 125(9):097024. [Abstract Henderson MW, Madenspacher JH, Whitehead GS, Thomas SY, Aloor JJ, Gowdy KM, Fessler MB. Effects of Orally Ingested Arsenic Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice. Environmental Health Perspectives 2017; Sep 28; 125(9):097024.]
  3. Gabor KA and Fessler MB. Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense. Current Molecular Pharmacology 2017; 10(1):27-45 [Abstract Gabor KA and Fessler MB. Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense. Current Molecular Pharmacology 2017; 10(1):27-45]
  4. Fessler MB. A New Frontier in Immunometabolism: Cholesterol in Lung Health and Disease. Annals of the American Thoracic Society 2017; 14(Suppl. 5):S399-S405. [Abstract Fessler MB. A New Frontier in Immunometabolism: Cholesterol in Lung Health and Disease. Annals of the American Thoracic Society 2017; 14(Suppl. 5):S399-S405.]
  5. Bowler RP, Wendt CH, Fessler MB, Foster MW, Kelly RS, Lasky-Su J, Rogers AJ, Stringer KA, Winston BW. An Official American Thoracic Society Workshop Report: New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society 2017; 14(12):1721-1743. [Abstract Bowler RP, Wendt CH, Fessler MB, Foster MW, Kelly RS, Lasky-Su J, Rogers AJ, Stringer KA, Winston BW. An Official American Thoracic Society Workshop Report: New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society 2017; 14(12):1721-1743.]
  6. Fessler MB. CO2 as a Potential Obesogen: A Gas That Will Stick to Your Ribs. American Journal of Respiratory Cell and Molecular Biology 2017; 57(5):499-500 [Invited editorial] [Abstract Fessler MB. CO2 as a Potential Obesogen: A Gas That Will Stick to Your Ribs. American Journal of Respiratory Cell and Molecular Biology 2017; 57(5):499-500 [Invited editorial]]
  7. Suratt BT, Ubags N, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JH, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, Miller YI, Fessler MB, Birukov K, Summer RS, Shore SA, Dixon AE. An Official American Thoracic Society Workshop Report: Obesity & Metabolism. An Emerging Frontier in Lung Health and Disease. Ann Am Thorac Soc 2017 Jun; 14(6):1050-1059.
  8. Sakamachi Y, Morioka S, Mihaly SR, Takaesu G, Foley JF, Fessler MB, Ninomiya-Tsuji J. TAK1 regulates resident macrophages by protecting lysosomal integrity. Cell Death & Disease 2017 Feb 9;8(2):e2598. [Abstract Sakamachi Y, Morioka S, Mihaly SR, Takaesu G, Foley JF, Fessler MB, Ninomiya-Tsuji J. TAK1 regulates resident macrophages by protecting lysosomal integrity. Cell Death & Disease 2017 Feb 9;8(2):e2598.]
  9. Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, Zeldin DC. House dust endotoxin and peripheral leukocyte counts: results from two large epidemiologic studies. Environmental Health Perspectives 2017 (in press). [Abstract Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, Zeldin DC. House dust endotoxin and peripheral leukocyte counts: results from two large epidemiologic studies. Environmental Health Perspectives 2017 (in press).]
  10. Lowe JM, Nguyen TA, Resnick MA, Grimm SA, Gabor KA, Peddada SD, Anderson CW, Menendez D, Fessler MB. Novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression. Cell Death & Differentiation 2017; 24(1): 181-191. [Abstract Lowe JM, Nguyen TA, Resnick MA, Grimm SA, Gabor KA, Peddada SD, Anderson CW, Menendez D, Fessler MB. Novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression. Cell Death & Differentiation 2017; 24(1): 181-191.]

2016

  1. Fessler MB and Summer RS. Surfactant lipids at the host-environment interface: metabolic sensors, suppressors, and effectors of inflammatory lung disease. American Journal of Respiratory Cell and Molecular Biology 2016; 54(5):624-35. [Abstract Fessler MB and Summer RS. Surfactant lipids at the host-environment interface: metabolic sensors, suppressors, and effectors of inflammatory lung disease. American Journal of Respiratory Cell and Molecular Biology 2016; 54(5):624-35.]
  2. Shaikh SR, Fessler MB, Gowdy KM. Role for phospholipid acyl chains and cholesterol in pulmonary infections and inflammation. Journal of Leukocyte Biology 2016; 100(5):985-997. [Abstract Shaikh SR, Fessler MB, Gowdy KM. Role for phospholipid acyl chains and cholesterol in pulmonary infections and inflammation. Journal of Leukocyte Biology 2016; 100(5):985-997.]
  3. Fessler MB. The intracellular cholesterol landscape: dynamic integrator of the immune response. [Invited review article; cover image]. Trends in Immunology 2016; 37(12): 819-830. [Abstract Fessler MB. The intracellular cholesterol landscape: dynamic integrator of the immune response. [Invited review article; cover image]. Trends in Immunology 2016; 37(12): 819-830.]
  4. Chakrabarty JK, Naik AG, Fessler MB, Munske GR, Chowdhury SM. Differential Tandem Mass Spectrometry-Based Cross Linker: A New Approach for High Confidence in Identifying Protein Cross-Linking. Analytical Chemistry 2016; 88(20): 10215-10222. [Abstract Chakrabarty JK, Naik AG, Fessler MB, Munske GR, Chowdhury SM. Differential Tandem Mass Spectrometry-Based Cross Linker: A New Approach for High Confidence in Identifying Protein Cross-Linking. Analytical Chemistry 2016; 88(20): 10215-10222.]
  5. Speen AM, Kim HH, Bauer RN, Meyer M, Gowdy KM, Fessler MB, Duncan KE, Liu W, Porter NA, Jaspers I. Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling: A Potential Role for Lipid-Protein Adducts. Journal of Biological Chemistry 2016 Oct 4. [Abstract Speen AM, Kim HH, Bauer RN, Meyer M, Gowdy KM, Fessler MB, Duncan KE, Liu W, Porter NA, Jaspers I. Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling: A Potential Role for Lipid-Protein Adducts. Journal of Biological Chemistry 2016 Oct 4.]
  6. Nick JA, Caceres SM, Kret JE, Pock KR, Strand M, Faino A, Nichols DP, Saavedra MT, Taylor-Cousar JL, Coldren CD, Geraci MW, Burnham EL, Fessler MB, Suratt BT, Abraham E, Moss M, Malcolm KC. Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome. PLoS One 2016; 11(9): e0162490. [Abstract Nick JA, Caceres SM, Kret JE, Pock KR, Strand M, Faino A, Nichols DP, Saavedra MT, Taylor-Cousar JL, Coldren CD, Geraci MW, Burnham EL, Fessler MB, Suratt BT, Abraham E, Moss M, Malcolm KC. Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome. PLoS One 2016; 11(9): e0162490.]
  7. Barna BP, McPeek M, Malur A, Fessler MB, Wingard CJ, Dobbs L, Verbanac K, Bowling M, Judson M, Thomassen MJ. Elevated miRNA-33 in Sarcoidosis and Carbon Nanotube Model of Chronic Granulomatous Disease is Associated with Lipid Transporter Deficiency. American Journal of Respiratory Cell and Molecular Biology 2016; 54(6):865-71. [Abstract Barna BP, McPeek M, Malur A, Fessler MB, Wingard CJ, Dobbs L, Verbanac K, Bowling M, Judson M, Thomassen MJ. Elevated miRNA-33 in Sarcoidosis and Carbon Nanotube Model of Chronic Granulomatous Disease is Associated with Lipid Transporter Deficiency. American Journal of Respiratory Cell and Molecular Biology 2016; 54(6):865-71.]
  8. Lai L, Azzam KM, Lin WC, Rai P, Lowe JM, Gabor KA, Madenspacher JH, Aloor JJ, Parks JS, Näär AM, Fessler MB. MicroRNA-33 regulates the innate immune response via ATP Binding Cassette transporter-mediated remodeling of membrane microdomains. Journal of Biological Chemistry 2016; 291(37):19651-60. [Abstract Lai L, Azzam KM, Lin WC, Rai P, Lowe JM, Gabor KA, Madenspacher JH, Aloor JJ, Parks JS, Näär AM, Fessler MB. MicroRNA-33 regulates the innate immune response via ATP Binding Cassette transporter-mediated remodeling of membrane microdomains. Journal of Biological Chemistry 2016; 291(37):19651-60.]
  9. Madenspacher JH, Fessler MB. A non-invasive and technically non-intensive method for induction and phenotyping of experimental bacterial pneumonia in mice. Journal of Visualized Experiments 2016; Sep 28 (115). [Abstract Madenspacher JH, Fessler MB. A non-invasive and technically non-intensive method for induction and phenotyping of experimental bacterial pneumonia in mice. Journal of Visualized Experiments 2016; Sep 28 (115).]

2015

  1. Chowdhury SM, Zhu X, Aloor JJ, Azzam KM, Gabor KA, Ge W, Addo KA, Tomer KB, Parks JS, Fessler MB. Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling. Molecular & cellular proteomics: MCP 2015 14(7):1859-1870. [Abstract Chowdhury SM, Zhu X, Aloor JJ, Azzam KM, Gabor KA, Ge W, Addo KA, Tomer KB, Parks JS, Fessler MB. Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling. Molecular & cellular proteomics: MCP 2015 14(7):1859-1870.]
  2. Gowdy KM, Madenspacher JH, Azzam KM, Gabor KA, Janardhan KS, Aloor JJ, Fessler MB.  Key Role for Scavenger Receptor B-I in the Integrative Physiology of Host Defense during Bacterial Pneumonia. Mucosal Immunology 2015; 8(3):559-71 [Abstract Gowdy KM, Madenspacher JH, Azzam KM, Gabor KA, Janardhan KS, Aloor JJ, Fessler MB.  Key Role for Scavenger Receptor B-I in the Integrative Physiology of Host Defense during Bacterial Pneumonia. Mucosal Immunology 2015; 8(3):559-71]
  3. Fessler MB. Regulation of Adaptive Immunity in Health and Disease by Cholesterol Metabolism. Current allergy and asthma reports 2015 15(8):548-. [Abstract Fessler MB. Regulation of Adaptive Immunity in Health and Disease by Cholesterol Metabolism. Current allergy and asthma reports 2015 15(8):548-.]
  4. Gabor KA and Fessler MB.  Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense. Current Molecular Pharmacology (in press).
  5. Fessler MB.  Revisiting ‘Good’ and ‘Bad’ Cholesterol: The Battle Over Flow Through Arteries Now Shifts to Flow Through Airways. American Journal of Respiratory and Critical Care Medicine 2015; 191(9):969-970 [Invited editorial] [Abstract Fessler MB.  Revisiting ‘Good’ and ‘Bad’ Cholesterol: The Battle Over Flow Through Arteries Now Shifts to Flow Through Airways. American Journal of Respiratory and Critical Care Medicine 2015; 191(9):969-970 [Invited editorial]]

2014

  1. Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. Reply: To PMID 22921873. The Journal of Allergy and Clinical Immunology 2014 131(6):1715-1716. [Abstract Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. Reply: To PMID 22921873. The Journal of Allergy and Clinical Immunology 2014 131(6):1715-1716.]
  2. Romero F, Shah D, Duong M, Penn RB, Fessler MB, Madenspacher J, Stafstrom W, Kavuru M, Lu B, Kallen CB, Walsh K, Summer R.  A Pneumocyte-macrophage Paracrine Lipid Axis Drives the Lung Toward Fibrosis. American Journal of Respiratory Cell and Molecular Biology 2014 Nov 19.   [Abstract Romero F, Shah D, Duong M, Penn RB, Fessler MB, Madenspacher J, Stafstrom W, Kavuru M, Lu B, Kallen CB, Walsh K, Summer R.  A Pneumocyte-macrophage Paracrine Lipid Axis Drives the Lung Toward Fibrosis. American Journal of Respiratory Cell and Molecular Biology 2014 Nov 19.  ]
  3. Henry SC, Schmidt E, Fessler MB, Taylor GA.  Palmitoylation of Irgm1 cooperates with the αK amphipathic helix to mediate membrane binding. PLoS ONE 2014; 9(4):e95021. [Abstract Henry SC, Schmidt E, Fessler MB, Taylor GA.  Palmitoylation of Irgm1 cooperates with the αK amphipathic helix to mediate membrane binding. PLoS ONE 2014; 9(4):e95021.]
  4. Lowe JM, Menendez D, Bushel PR, Garantziotis S, Fessler MB*, Resnick MA*.  p53 and NF-κB cooperatively promote pro-inflammatory gene expression in primary human macrophages. Cancer Research 2014; 74(8):2182-92.  *Equal contribution [Abstract Lowe JM, Menendez D, Bushel PR, Garantziotis S, Fessler MB*, Resnick MA*.  p53 and NF-κB cooperatively promote pro-inflammatory gene expression in primary human macrophages. Cancer Research 2014; 74(8):2182-92.  *Equal contribution]
  5. Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB. APOε4 is associated with enhanced in vivo innate immune responses in human subjects.Journal of Allergy and Clinical Immunology 2014 134(1):127-134. [Abstract Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB. APOε4 is associated with enhanced in vivo innate immune responses in human subjects.Journal of Allergy and Clinical Immunology 2014 134(1):127-134.]
  6. Yamashita CM*, Fessler MB*, Vasanthamohan L, Lac J, Madenspacher J, McCaig L, Yao LJ, Puntorieri V, Wang LF, Mehta S, Lewis JF, Veldhuizen RAW. Apolipoprotein E Deficient Mice are Susceptible to the Development of Acute Lung Injury.  *Equal contribution. Respiration 2014; 87(5):416-27. [Abstract Yamashita CM*, Fessler MB*, Vasanthamohan L, Lac J, Madenspacher J, McCaig L, Yao LJ, Puntorieri V, Wang LF, Mehta S, Lewis JF, Veldhuizen RAW. Apolipoprotein E Deficient Mice are Susceptible to the Development of Acute Lung Injury.  *Equal contribution. Respiration 2014; 87(5):416-27.]
  7. Freeman SR, Jin X, Anzinger JJ, Xu Q, Purushothaman S, Fessler MB, Addadi L, Kruth HS. ABCG1-Mediated Generation of Extracellular Cholesterol Microdomains. Journal of Lipid Research 2014; 55(1):115-27. [Abstract Freeman SR, Jin X, Anzinger JJ, Xu Q, Purushothaman S, Fessler MB, Addadi L, Kruth HS. ABCG1-Mediated Generation of Extracellular Cholesterol Microdomains. Journal of Lipid Research 2014; 55(1):115-27.]
  8. Lowe JM, Menendez D, Fessler MB.  A new inflammatory role for p53 in human macrophages. Cell Cycle 2014; 13 (19):2983-4 [Invited editorial] [Abstract Lowe JM, Menendez D, Fessler MB.  A new inflammatory role for p53 in human macrophages. Cell Cycle 2014; 13 (19):2983-4 [Invited editorial]]

2013

  1. Gowdy KM, Fessler MB. Emerging roles for cholesterol and lipoproteins in lung disease. Pulmonary pharmacology & therapeutics 2013 26(4):430-437. [Abstract Gowdy KM, Fessler MB. Emerging roles for cholesterol and lipoproteins in lung disease. Pulmonary pharmacology & therapeutics 2013 26(4):430-437.]
  2. Fessler MB, Rose K, Zhang Y, Jaramillo R and Zeldin DC. (2013) Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population. J Lipid Res, 54, 3177-88. [Abstract Fessler MB, Rose K, Zhang Y, Jaramillo R and Zeldin DC. (2013) Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population. J Lipid Res, 54, 3177-88.]
  3. Madenspacher JH, Azzam KM, Gowdy KM, Malcolm KC, Nick JA, Dixon D, Aloor JJ, Draper DW, Guardiola JJ, Shatz M, Menendez D, Lowe J, Lu J, Bushel P, Li L, Merrick BA, Resnick MA, Fessler MB. p53 Integrates host defense and cell fate during bacterial pneumonia.  Journal of Experimental Medicine 2013 210(5):891-904. [Abstract Madenspacher JH, Azzam KM, Gowdy KM, Malcolm KC, Nick JA, Dixon D, Aloor JJ, Draper DW, Guardiola JJ, Shatz M, Menendez D, Lowe J, Lu J, Bushel P, Li L, Merrick BA, Resnick MA, Fessler MB. p53 Integrates host defense and cell fate during bacterial pneumonia.  Journal of Experimental Medicine 2013 210(5):891-904.]
  4. Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. (2013) Relation between objective measures of atopy and myocardial infarction in the United States. J Allergy and Clin Immunol, 131:405-411. [Abstract Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. (2013) Relation between objective measures of atopy and myocardial infarction in the United States. J Allergy and Clin Immunol, 131:405-411.]
  5. Palvinskaya T, Antkowiak M, Burg E, Lenox CC, Ubags N, Cramer A, Rincón M, Dixon AE, Fessler MB, Poynter ME, Suratt BT. Effects of acute and chronic low density lipoprotein exposure on neutrophil function. Pulmonary pharmacology & therapeutics 2013 26(4):405-411.  [Abstract Palvinskaya T, Antkowiak M, Burg E, Lenox CC, Ubags N, Cramer A, Rincón M, Dixon AE, Fessler MB, Poynter ME, Suratt BT. Effects of acute and chronic low density lipoprotein exposure on neutrophil function. Pulmonary pharmacology & therapeutics 2013 26(4):405-411. ]
  6. Santos AJ, Meinecke M, Fessler MB, Holden DW, Boucrot E. Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase. Journal of cell science 2013; 126(Pt. 14):2990-2996.  [Abstract Santos AJ, Meinecke M, Fessler MB, Holden DW, Boucrot E. Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase. Journal of cell science 2013; 126(Pt. 14):2990-2996. ]
  7. Kordonowy LL, Burg E, Lenox CC, Gauthier LM, Petty JM, Antkowiak M, Palvinskaya T, Ubags N, Rincon M, Dixon AE, Vernooy JH, Fessler MB, Poynter ME, Suratt BT. Obesity is associated with neutrophil dysfunction and attenuation of murine acute lung injury. American journal of respiratory cell and molecular biology 2013; 47(1):120-127. [Abstract Kordonowy LL, Burg E, Lenox CC, Gauthier LM, Petty JM, Antkowiak M, Palvinskaya T, Ubags N, Rincon M, Dixon AE, Vernooy JH, Fessler MB, Poynter ME, Suratt BT. Obesity is associated with neutrophil dysfunction and attenuation of murine acute lung injury. American journal of respiratory cell and molecular biology 2013; 47(1):120-127.]
  8. Dhungana S, Merrick BA, Tomer KB, Fessler MB. Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide. Molecular & Cellular Proteomics: MCP 2013; 8(1):201-213. [Abstract Dhungana S, Merrick BA, Tomer KB, Fessler MB. Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide. Molecular & Cellular Proteomics: MCP 2013; 8(1):201-213.]
  9. Lord CC, Betters JL, Ivanova PT, Milne SB, Myers DS, Madenspacher J, Thomas G, Chung S, Liu M , Davis MA, Lee RG, Crooke RM, Graham MJ, Parks JS, Brasaemle DL, Fessler MB, Brown HA, Brown JM. CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action. Diabetes 2013; 61(2):355-363. [Abstract Lord CC, Betters JL, Ivanova PT, Milne SB, Myers DS, Madenspacher J, Thomas G, Chung S, Liu M , Davis MA, Lee RG, Crooke RM, Graham MJ, Parks JS, Brasaemle DL, Fessler MB, Brown HA, Brown JM. CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action. Diabetes 2013; 61(2):355-363.]

2012

  1. Suratt BT, Fessler MB. Greasing the Way: The ABCS of HSPC Efflux From the Marrow. Cell stem cell 2012 Aug; 11(2):143-144.  [Abstract Suratt BT, Fessler MB. Greasing the Way: The ABCS of HSPC Efflux From the Marrow. Cell stem cell 2012 Aug; 11(2):143-144. ] 
  2. Fessler MB. Next stop for HDL: the lung. Clin Exp Allergy 2012 42(3):340-342. [Abstract Fessler MB. Next stop for HDL: the lung. Clin Exp Allergy 2012 42(3):340-342.] 
  3. Draper DW, Gowdy KM, Madenspacher JH, Wilson RH, Whitehead GS, Nakano H, Pandiri AR, Foley JF, Remaley AT, Cook DN, Fessler MB. ATP binding cassette transporter G1 deletion induces IL-17-dependent dysregulation of pulmonary adaptive immunity. Journal of Immunology 188(11):5327-2336, 2012. [Abstract Draper DW, Gowdy KM, Madenspacher JH, Wilson RH, Whitehead GS, Nakano H, Pandiri AR, Foley JF, Remaley AT, Cook DN, Fessler MB. ATP binding cassette transporter G1 deletion induces IL-17-dependent dysregulation of pulmonary adaptive immunity. Journal of Immunology 188(11):5327-2336, 2012.]
  4. Madenspacher JH , Azzam KM, Gong W, Gowdy KM, Vitek MP, Laskowitz DT, Remaley AT, Wang JM, Fessler MB. Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. The Journal of biological chemistry 2012 287(52):43730-43740. [Abstract Madenspacher JH , Azzam KM, Gong W, Gowdy KM, Vitek MP, Laskowitz DT, Remaley AT, Wang JM, Fessler MB. Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. The Journal of biological chemistry 2012 287(52):43730-43740.]
  5. Azzam KM, Fessler MB. Crosstalk between reverse cholesterol transport and innate immunity. Trends in endocrinology and metabolism: TEM 2012 23(4):169-178. [Abstract Azzam KM, Fessler MB. Crosstalk between reverse cholesterol transport and innate immunity. Trends in endocrinology and metabolism: TEM 2012 23(4):169-178.]

2011

  1. Merrick BA, Dhungana S, Williams JG, Aloor JJ, Peddada S, Tomer KB, Fessler MB. Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3. Molecular & Cellular Proteomics: MCP 2011; 10(10):M110.006. [Abstract Merrick BA, Dhungana S, Williams JG, Aloor JJ, Peddada S, Tomer KB, Fessler MB. Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3. Molecular & Cellular Proteomics: MCP 2011; 10(10):M110.006.]
  2. Menendez, D., Shatz, M., Garantziotis, S., Fessler, M., and Resnick, M.A.  The human Toll-like receptor family is integrated into human DNA damage and p53 network. Mar;7(3):e1001360. Epub 2011 Mar 31   [Abstract Menendez, D., Shatz, M., Garantziotis, S., Fessler, M., and Resnick, M.A.  The human Toll-like receptor family is integrated into human DNA damage and p53 network. Mar;7(3):e1001360. Epub 2011 Mar 31  ]
  3. Fessler MB, Parks JS. Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling. Journal of Immunology 2011; 187(4):1529-1535. [Abstract Fessler MB, Parks JS. Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling. Journal of Immunology 2011; 187(4):1529-1535.]

2010

  1. Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of Serum Cholesterol Levels to Atopy in the U.S. Population. Allergy 65:859-64. [Abstract Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of Serum Cholesterol Levels to Atopy in the U.S. Population. Allergy 65:859-64.] [Full Text Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of Serum Cholesterol Levels to Atopy in the U.S. Population. Allergy 65:859-64.] [PDF Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of Serum Cholesterol Levels to Atopy in the U.S. Population. Allergy 65:859-64.]
  2. Brown JM, Chung S, Sawyer JK, Degirolamo, C, Alger HM, Nguyen T, Zhu X, Duong MN, Brown AL, Shah R, Davis MA, Kelley K, Wilson MD, Fessler MB, Parks JS, Rudel LL. Combined Therapy of dietary Fish Oil and Stearoyl-CoA Desaturase 1 (SCD1) Inhibition Prevents the Metabolic Syndrome and Atherosclerosis. Arteriosclerosis, Thombosis, and Vascular Biology 2010; 30(1):24-30. [Abstract Brown JM, Chung S, Sawyer JK, Degirolamo, C, Alger HM, Nguyen T, Zhu X, Duong MN, Brown AL, Shah R, Davis MA, Kelley K, Wilson MD, Fessler MB, Parks JS, Rudel LL. Combined Therapy of dietary Fish Oil and Stearoyl-CoA Desaturase 1 (SCD1) Inhibition Prevents the Metabolic Syndrome and Atherosclerosis. Arteriosclerosis, Thombosis, and Vascular Biology 2010; 30(1):24-30.]
  3. Mueller GA, Edwards L, Aloor J, Fessler MB, Pomes A, Chapman M, London RE, Pedersen LC. The Structure of the House Dust Mite Allergen Der p 7 Reveals Similarities to the Human Innate Immune Protein LBP. Journal of Allergy and Clinical Immunology 2010; 125(4):909-17. [Abstract Mueller GA, Edwards L, Aloor J, Fessler MB, Pomes A, Chapman M, London RE, Pedersen LC. The Structure of the House Dust Mite Allergen Der p 7 Reveals Similarities to the Human Innate Immune Protein LBP. Journal of Allergy and Clinical Immunology 2010; 125(4):909-17.]
  4. Smoak KA, Aloor JJ, Madenspacher JH, Merrick BA, Collins JB, Zhu X, Cavigiolio G, Oda MN, Parks JS, Fessler MB. Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation. Cell Metabolism 2010; 11(6):493-502. [Abstract Smoak KA, Aloor JJ, Madenspacher JH, Merrick BA, Collins JB, Zhu X, Cavigiolio G, Oda MN, Parks JS, Fessler MB. Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation. Cell Metabolism 2010; 11(6):493-502.]
  5. Draper DW, Madenspacher JH, King DH, Remaley AT, Fessler MB. ATP Binding Cassette Transporter G1 Deficiency Dysregulates Host Defense in the Lung. American Journal of Respiratory and Critical Care Medicine 2010; 182(3):404-12. [Abstract Draper DW, Madenspacher JH, King DH, Remaley AT, Fessler MB. ATP Binding Cassette Transporter G1 Deficiency Dysregulates Host Defense in the Lung. American Journal of Respiratory and Critical Care Medicine 2010; 182(3):404-12.]
  6. Madenspacher JH, Draper DW, Smoak KA, Li H, Suratt BT, Wilson MD, Rudel LL, Fessler MB. Dyslipidemia Exerts Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense through Divergent TLR Response Phenotypes. Journal of Immunology 2010; 185(3): 1660-9. [Abstract Madenspacher JH, Draper DW, Smoak KA, Li H, Suratt BT, Wilson MD, Rudel LL, Fessler MB. Dyslipidemia Exerts Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense through Divergent TLR Response Phenotypes. Journal of Immunology 2010; 185(3): 1660-9.]
  7. Schug T, Xu Q, Draper DW, de Silva AP, Purushotham A, Fessler MB, Li X. SIRT1 regulates NF-κB-dependent transcription and attenuates macrophage-mediated inflammation. Molecular & Cellular Biology 2010; 30(19): 4712-21.
  8. Zhu X, Owen JS, Wilson M, Thomas MJ, Hiltbold-Schwartz E, Fessler MB, Parks JS. Macrophage ABCA1 Dampens MyD88 Dependent Toll-Like Receptor Signaling Through Modulation of Free Cholesterol Enrichment in Lipid Rafts. Journal of Lipid Research 2010; 51(11):3196-206. [Abstract Zhu X, Owen JS, Wilson M, Thomas MJ, Hiltbold-Schwartz E, Fessler MB, Parks JS. Macrophage ABCA1 Dampens MyD88 Dependent Toll-Like Receptor Signaling Through Modulation of Free Cholesterol Enrichment in Lipid Rafts. Journal of Lipid Research 2010; 51(11):3196-206.]
  9. Balamayooran G, Batra S, Fessler MB, Happel KI, Jeyaseelan S. Mechanisms of Neutrophil Accumulation in the Lungs Against Bacteria. American Journal of Respiratory Cell & Molecular Biology 2010; 43(1):5-16. [Abstract Balamayooran G, Batra S, Fessler MB, Happel KI, Jeyaseelan S. Mechanisms of Neutrophil Accumulation in the Lungs Against Bacteria. American Journal of Respiratory Cell & Molecular Biology 2010; 43(1):5-16.]

2009

  1. Fessler MB, Massing MW, Spruell B, Jaramillo R, Draper D, Madenspacher J, Arbes S, Calatroni A, Zeldin DC. Novel Relationship of Serum Cholesterol with Asthma and Wheeze in the United States. Journal of Allergy and Clinical Immunology 2009; 124(5):967-74. (Corresponding author) [Abstract Fessler MB, Massing MW, Spruell B, Jaramillo R, Draper D, Madenspacher J, Arbes S, Calatroni A, Zeldin DC. Novel Relationship of Serum Cholesterol with Asthma and Wheeze in the United States. Journal of Allergy and Clinical Immunology 2009; 124(5):967-74. (Corresponding author)]
  2. Dhungana S, Merrick BA, Tomer K, Fessler MB. Quantitative Proteomic Analysis of Macrophage Rafts Reveals Compartmentalized Activation of the Proteasome and of Proteasome-mediated ERK Activation in Response to Lipopolysaccharide. Molecular & Cellular Proteomics 2009; 8(1):201-213. [Abstract Dhungana S, Merrick BA, Tomer K, Fessler MB. Quantitative Proteomic Analysis of Macrophage Rafts Reveals Compartmentalized Activation of the Proteasome and of Proteasome-mediated ERK Activation in Response to Lipopolysaccharide. Molecular & Cellular Proteomics 2009; 8(1):201-213.]
  3. Dhungana S, Fessler MB, Tomer KB. Epitope Mapping by Proteolysis of Antigen-Antibody Complexes. Methods in Molecular Biology 2009; 524:87-101. [Abstract Dhungana S, Fessler MB, Tomer KB. Epitope Mapping by Proteolysis of Antigen-Antibody Complexes. Methods in Molecular Biology 2009; 524:87-101.]
  4. Dhungana S, Fessler MB, Tomer KB. Epitope Mapping by Differential Chemical Modification of Antigens. Methods in Molecular Biology 2009; 524:119-34. [Abstract Dhungana S, Fessler MB, Tomer KB. Epitope Mapping by Differential Chemical Modification of Antigens. Methods in Molecular Biology 2009; 524:119-34.]
  5. Fessler MB, Rudel LL, Brown MA. Toll-like Receptor Signaling Links Dietary Fatty Acids to the Metabolic Syndrome. Current Opinion in Lipidology 2009; 20(5):3799-85. [Abstract Fessler MB, Rudel LL, Brown MA. Toll-like Receptor Signaling Links Dietary Fatty Acids to the Metabolic Syndrome. Current Opinion in Lipidology 2009; 20(5):3799-85.]
  6. Fessler, MB. Simvastatin as a Potential Therapeutic for Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine 2009; 180(10):1031. [Abstract Fessler, MB. Simvastatin as a Potential Therapeutic for Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine 2009; 180(10):1031.]

2008

  1. Smoak K, Madenspacher J, Jeyaseelan S, Williams B, Poch KR, Dixon D, Nick JA, Worthen GS, Fessler MB. Liver X Receptor Regulates Pulmonary Innate Immunity. Journal of Immunology 2008; 180(5):3305-12. [Abstract Smoak K, Madenspacher J, Jeyaseelan S, Williams B, Poch KR, Dixon D, Nick JA, Worthen GS, Fessler MB. Liver X Receptor Regulates Pulmonary Innate Immunity. Journal of Immunology 2008; 180(5):3305-12.]
  2. Fessler MB. Liver X Receptor: Crosstalk Node for the Signaling of Lipid Metabolism, Carbohydrate Metabolism, and Innate Immunity. Current Signal Transduction Therapy 2008; 3(2):75-81.
  3. Madenspacher JH, Smoak KA, Jeyaseelan S, Williams B, Poch KR, Nick JA, Worthen GS, Fessler MB. Liver X Receptor Agonists Modify Pulmonary Innate Immunity. Proceedings of the American Thoracic Society 2008; 5(3):366

2007

  1. Jeyaseelan S, Young SK, Fessler MB, Liu Y, Malcolm KC, Yamamoto M, Akira S, and Worthen GS. TRIF-Mediated Signaling Contributes to Innate Immune Responses in the Lung During Escherichia coli Pneumonia. Journal of Immunology 2007; 178(5):3153-60. [Abstract Jeyaseelan S, Young SK, Fessler MB, Liu Y, Malcolm KC, Yamamoto M, Akira S, and Worthen GS. TRIF-Mediated Signaling Contributes to Innate Immune Responses in the Lung During Escherichia coli Pneumonia. Journal of Immunology 2007; 178(5):3153-60.]
  2. Fessler MB, Arndt PG, Nick JA, Malcolm KC, Worthen GS. A Dual Role for RhoA in Suppression and Induction of Cytokines in the Human Neutrophil. Blood 2007; 109(3):1248-56. (Corresponding author) [Abstract Fessler MB, Arndt PG, Nick JA, Malcolm KC, Worthen GS. A Dual Role for RhoA in Suppression and Induction of Cytokines in the Human Neutrophil. Blood 2007; 109(3):1248-56. (Corresponding author)]
  3. Brass DM, Hollingsworth JW, Fessler MB, Savov JD, Maxwell AB, Whitehead GS, Burch LH, Schwartz DA. The IL-1 type 1 receptor is required for the development of LPS-induced airways disease. Journal of Allergy and Clinical Immunology 2007; 120(1):121-7. [Abstract Brass DM, Hollingsworth JW, Fessler MB, Savov JD, Maxwell AB, Whitehead GS, Burch LH, Schwartz DA. The IL-1 type 1 receptor is required for the development of LPS-induced airways disease. Journal of Allergy and Clinical Immunology 2007; 120(1):121-7.]

2006

  1. Fessler MB, Arndt PG, Just I, Nick JA, Malcolm KC, Worthen GS. A dual role for RhoA in suppression and induction of cytokines in the human neutrophil. Blood 2006;Oct 3 (in press). [Abstract Fessler MB, Arndt PG, Just I, Nick JA, Malcolm KC, Worthen GS. A dual role for RhoA in suppression and induction of cytokines in the human neutrophil. Blood 2006;Oct 3 (in press).]
  2. Cha SI, Fessler MB, Cool CD, Schwartz MI, Brown KK. Lymphoid interstitial pneumonia: clinical features, associations, and prognosis. Eur Res J 2006 Aug;28(2):364-9. [Abstract Cha SI, Fessler MB, Cool CD, Schwartz MI, Brown KK. Lymphoid interstitial pneumonia: clinical features, associations, and prognosis. Eur Res J 2006 Aug;28(2):364-9.]
  3. Morimoto K, Janssen WJ, Fessler MB, Xiao YQ, McPhillips KA, Borges VM, Kench JA, Henson PM, Vandivier RW. Statins enhance clearance of apoptotic cells through modulation of Rho-GTPases. Proc Am Thorac Soc 2006 Aug;3(6):516-7. [Abstract Morimoto K, Janssen WJ, Fessler MB, Xiao YQ, McPhillips KA, Borges VM, Kench JA, Henson PM, Vandivier RW. Statins enhance clearance of apoptotic cells through modulation of Rho-GTPases. Proc Am Thorac Soc 2006 Aug;3(6):516-7.]
  4. Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, Xiao YQ, Kench JA, Henson PM, Vandivier RW. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol 2006 Jun 15;176(12):7657-65. [Abstract Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, Xiao YQ, Kench JA, Henson PM, Vandivier RW. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol 2006 Jun 15;176(12):7657-65.]
  5. Friedlander AL, Fessler MB. A 70-year-old man with migratory pulmonary infiltrates. Chest 2006 Oct;130(4):1269-74. [Abstract Friedlander AL, Fessler MB. A 70-year-old man with migratory pulmonary infiltrates. Chest 2006 Oct;130(4):1269-74.]

2005

  1. Arcaroli J, Fessler MB, Abraham E. Genetic polymorphisms and sepsis. Shock Oct;24(4):300-12. [Abstract Arcaroli J, Fessler MB, Abraham E. Genetic polymorphisms and sepsis. Shock Oct;24(4):300-12.]
  2. Arndt PG, Young SK, Lieber JG, Fessler MB, Nick JA, Worthen GS. Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx. Am J Res Crit Care Med 2005 May 1;171(9):978-86. [Abstract Arndt PG, Young SK, Lieber JG, Fessler MB, Nick JA, Worthen GS. Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx. Am J Res Crit Care Med 2005 May 1;171(9):978-86.]
  3. Fessler MB, Young SK, Jeyaseelan S, Lieber JG, Arndt PG, Nick JA, Worthen GS. A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense. Am J Res Crit Care Med 2005 Mar 15;171(6):606-15. [Abstract Fessler MB, Young SK, Jeyaseelan S, Lieber JG, Arndt PG, Nick JA, Worthen GS. A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense. Am J Res Crit Care Med 2005 Mar 15;171(6):606-15.]
  4. Walker TS, Tomlin KL, Worthen GS, Poch KR, Lieber JG, Saavedra MT, Fessler MB, Malcolm KC, Vasil ML, Nick JA. Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect Immun 2005 Jun;73(6):3693-701. [Abstract Walker TS, Tomlin KL, Worthen GS, Poch KR, Lieber JG, Saavedra MT, Fessler MB, Malcolm KC, Vasil ML, Nick JA. Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect Immun 2005 Jun;73(6):3693-701.]

2004

  1. Frasch SC, Henson PM, Nagaosa K, Fessler MB, Borregaard N, Bratton L. Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR 1) co-localize to uropod rafts in formulated Met-Leu-Phe-stimulated neutrophils. J Biol Chem 2004 Apr 23;279(17):17625-33. [Abstract Frasch SC, Henson PM, Nagaosa K, Fessler MB, Borregaard N, Bratton L. Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR 1) co-localize to uropod rafts in formulated Met-Leu-Phe-stimulated neutrophils. J Biol Chem 2004 Apr 23;279(17):17625-33.]
  2. Fessler MB, Cool CD, Miller Y, Schwarz MI, Brown KK. Idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells in a patient with acromegaly. Respirology 2004 Jun;9(2):274-7. [Abstract Fessler MB, Cool CD, Miller Y, Schwarz MI, Brown KK. Idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells in a patient with acromegaly. Respirology 2004 Jun;9(2):274-7.]
  3. Fessler MB, Arndt PG, Frasch SC, Lieber JG, Johnson CA, Murphy RC, Nick JA, Bratton DL, Malcolm KC, Worthen GS. Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil. J Biol Chem 2004 Sep 17;279(38):39989-98. [Abstract Fessler MB, Arndt PG, Frasch SC, Lieber JG, Johnson CA, Murphy RC, Nick JA, Bratton DL, Malcolm KC, Worthen GS. Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil. J Biol Chem 2004 Sep 17;279(38):39989-98.]
  4. Fessler MB. New experimental approaches to the signaling of innate immunity. Am J Respir Cell Mol Biol 2004;31:S1-81S.

2003

  1. Fessler MB, Lepore JJ, Thompson BT, Semigran MJ. Right-to-Left shunting through a patent foramen ovale in right ventricular infarction: improvement of hypoxemia and hemodynamics with inhaled nitric oxide. J Clin Anesth 2003 Aug;15(5):371-4. [Abstract Fessler MB, Lepore JJ, Thompson BT, Semigran MJ. Right-to-Left shunting through a patent foramen ovale in right ventricular infarction: improvement of hypoxemia and hemodynamics with inhaled nitric oxide. J Clin Anesth 2003 Aug;15(5):371-4.]
  2. Fessler MB, O’Brien JM, Douglas IS. Laboratory predictors of relative adrenal insufficiency in septic shock. Crit Care Med 2003 Aug;31(8):2251-2. [Abstract Fessler MB, O’Brien JM, Douglas IS. Laboratory predictors of relative adrenal insufficiency in septic shock. Crit Care Med 2003 Aug;31(8):2251-2.]

2002

  1. Fessler MB, Malcolm KC, Duncan MW, Worthen GS. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase. J Biol Chem 2002 Aug 30;277(35):31291-302. [Abstract Fessler MB, Malcolm KC, Duncan MW, Worthen GS. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase. J Biol Chem 2002 Aug 30;277(35):31291-302.]
  2. Fessler MB, Malcolm KC, Duncan MW, Worthen GS. Lipopolysaccharide stimulation of the human neutrophil: an analysis of changes in gene transcription and protein expression by oligonucleotide microarrays and proteomics. Chest 2002 Mar;121(3 Suppl):75S-76S. [Abstract Fessler MB, Malcolm KC, Duncan MW, Worthen GS. Lipopolysaccharide stimulation of the human neutrophil: an analysis of changes in gene transcription and protein expression by oligonucleotide microarrays and proteomics. Chest 2002 Mar;121(3 Suppl):75S-76S.]
  3. Wang TJ, Mort EA, Nordberg P, Chang Y, Cadigan ME, Mylott L, Ananian LV, Thompson BT, Fessler M, Warren W, Wheeler A, Jordan M, Fifer MA. A utilization management intervention to reduce unnecessary testing in the coronary care unit. Arch Intern Med 2002 Sep 9;162(16):1885-90. [Abstract Wang TJ, Mort EA, Nordberg P, Chang Y, Cadigan ME, Mylott L, Ananian LV, Thompson BT, Fessler M, Warren W, Wheeler A, Jordan M, Fifer MA. A utilization management intervention to reduce unnecessary testing in the coronary care unit. Arch Intern Med 2002 Sep 9;162(16):1885-90.]

1999

  1. Hess DR, Medoff BD, Fessler MB. Pulmonary mechanics and graphics during positive pressure ventilation. Int Anesthesiol Clin 1999 Summer;37(3):15-34. [Abstract Hess DR, Medoff BD, Fessler MB. Pulmonary mechanics and graphics during positive pressure ventilation. Int Anesthesiol Clin 1999 Summer;37(3):15-34.]
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