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Selected Publications

Environmental Cardiopulmonary Disease Group

Cytochrome P450

  1. Zeldin DC, Corcia A and Armstrong WM. (1985) Cyclic AMP-induced changes in membrane conductance of Necturus gallbladder epithelial cells. J Membr Biol, 84, 193-206. [Abstract Zeldin DC, Corcia A and Armstrong WM. (1985) Cyclic AMP-induced changes in membrane conductance of Necturus gallbladder epithelial cells. J Membr Biol, 84, 193-206.]
  2. Zeldin DC, Kobayashi J, Falck JR, Winder BS, Hammock BD, Snapper JR and Capdevila JH. (1993) Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase. J Biol Chem, 268, 6402-7. [Abstract Zeldin DC, Kobayashi J, Falck JR, Winder BS, Hammock BD, Snapper JR and Capdevila JH. (1993) Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase. J Biol Chem, 268, 6402-7.] [PDF Zeldin DC, Kobayashi J, Falck JR, Winder BS, Hammock BD, Snapper JR and Capdevila JH. (1993) Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase. J Biol Chem, 268, 6402-7.]
  3. Zeldin DC, DuBois RN, Falck JR and Capdevila JH. (1995) Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochem Biophys, 322, 76-86. [Abstract Zeldin DC, DuBois RN, Falck JR and Capdevila JH. (1995) Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochem Biophys, 322, 76-86.]
  4. Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM and Capdevila JH. (1995) The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. J Clin Invest, 95, 2150-60. [Abstract Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM and Capdevila JH. (1995) The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. J Clin Invest, 95, 2150-60.] [Full Text Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM and Capdevila JH. (1995) The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. J Clin Invest, 95, 2150-60.] [PDF Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM and Capdevila JH. (1995) The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. J Clin Invest, 95, 2150-60.]
  5. Zeldin DC, Wei S, Falck JR, Hammock BD, Snapper JR and Capdevila JH. (1995) Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys, 316, 443-51. [Abstract Zeldin DC, Wei S, Falck JR, Hammock BD, Snapper JR and Capdevila JH. (1995) Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys, 316, 443-51.]
  6. Wu S, Moomaw CR, Tomer KB, Falck JR and Zeldin DC. (1996) Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem, 271, 3460-8. [Abstract Wu S, Moomaw CR, Tomer KB, Falck JR and Zeldin DC. (1996) Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem, 271, 3460-8.] [Full Text Wu S, Moomaw CR, Tomer KB, Falck JR and Zeldin DC. (1996) Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem, 271, 3460-8.] [PDF Wu S, Moomaw CR, Tomer KB, Falck JR and Zeldin DC. (1996) Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem, 271, 3460-8.]
  7. Zeldin DC, Foley J, Ma J, Boyle JE, Pascual JM, Moomaw CR, Tomer KB, Steenbergen C and Wu S. (1996) CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. Mol Pharmacol, 50, 1111-7. [Abstract Zeldin DC, Foley J, Ma J, Boyle JE, Pascual JM, Moomaw CR, Tomer KB, Steenbergen C and Wu S. (1996) CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. Mol Pharmacol, 50, 1111-7.] [PDF Zeldin DC, Foley J, Ma J, Boyle JE, Pascual JM, Moomaw CR, Tomer KB, Steenbergen C and Wu S. (1996) CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. Mol Pharmacol, 50, 1111-7.]
  8. Zeldin DC, Moomaw CR, Jesse N, Tomer KB, Beetham J, Hammock BD and Wu S. (1996) Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway. Arch Biochem Biophys, 330, 87-96. [Abstract Zeldin DC, Moomaw CR, Jesse N, Tomer KB, Beetham J, Hammock BD and Wu S. (1996) Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway. Arch Biochem Biophys, 330, 87-96.]
  9. Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR and Zeldin DC. (1997) Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem, 272, 12551-9. [Abstract Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR and Zeldin DC. (1997) Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem, 272, 12551-9.] [Full Text Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR and Zeldin DC. (1997) Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem, 272, 12551-9.] [PDF Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR and Zeldin DC. (1997) Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem, 272, 12551-9.]
  10. Zeldin DC, Foley J, Boyle JE, Moomaw CR, Tomer KB, Parker C, Steenbergen C and Wu S. (1997) Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology, 138, 1338-46. [Abstract Zeldin DC, Foley J, Boyle JE, Moomaw CR, Tomer KB, Parker C, Steenbergen C and Wu S. (1997) Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology, 138, 1338-46.] [Full Text Zeldin DC, Foley J, Boyle JE, Moomaw CR, Tomer KB, Parker C, Steenbergen C and Wu S. (1997) Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology, 138, 1338-46.] [PDF Zeldin DC, Foley J, Boyle JE, Moomaw CR, Tomer KB, Parker C, Steenbergen C and Wu S. (1997) Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology, 138, 1338-46.]
  11. Zeldin DC, Foley J, Goldsworthy SM, Cook ME, Boyle JE, Ma J, Moomaw CR, Tomer KB, Steenbergen C and Wu S. (1997) CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance. Mol Pharmacol, 51, 931-43. [Abstract Zeldin DC, Foley J, Goldsworthy SM, Cook ME, Boyle JE, Ma J, Moomaw CR, Tomer KB, Steenbergen C and Wu S. (1997) CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance. Mol Pharmacol, 51, 931-43.]
  12. Luo G, Zeldin DC, Blaisdell JA, Hodgson E and Goldstein JA. (1998) Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys, 357, 45-57. [Abstract Luo G, Zeldin DC, Blaisdell JA, Hodgson E and Goldstein JA. (1998) Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys, 357, 45-57.] [PDF Luo G, Zeldin DC, Blaisdell JA, Hodgson E and Goldstein JA. (1998) Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys, 357, 45-57.]
  13. Ma J, Ramachandran S, Fiedorek FT, Jr. and Zeldin DC. (1998) Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics, 49, 152-5. [Abstract Ma J, Ramachandran S, Fiedorek FT, Jr. and Zeldin DC. (1998) Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics, 49, 152-5.]
  14. Pascual JM, McKenzie A, Yankaskas JR, Falck JR and Zeldin DC. (1998) Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells. J Pharmacol Exp Ther, 286, 772-9. [Abstract Pascual JM, McKenzie A, Yankaskas JR, Falck JR and Zeldin DC. (1998) Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells. J Pharmacol Exp Ther, 286, 772-9.] [Full Text Pascual JM, McKenzie A, Yankaskas JR, Falck JR and Zeldin DC. (1998) Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells. J Pharmacol Exp Ther, 286, 772-9.] [PDF Pascual JM, McKenzie A, Yankaskas JR, Falck JR and Zeldin DC. (1998) Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells. J Pharmacol Exp Ther, 286, 772-9.]
  15. Qu W, Rippe RA, Ma J, Scarborough P, Biagini C, Fiedorek FT, Travlos GS, Parker C and Zeldin DC. (1998) Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism. Mol Pharmacol, 54, 504-13. [Abstract Qu W, Rippe RA, Ma J, Scarborough P, Biagini C, Fiedorek FT, Travlos GS, Parker C and Zeldin DC. (1998) Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism. Mol Pharmacol, 54, 504-13.] [Full Text Qu W, Rippe RA, Ma J, Scarborough P, Biagini C, Fiedorek FT, Travlos GS, Parker C and Zeldin DC. (1998) Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism. Mol Pharmacol, 54, 504-13.] [PDF Qu W, Rippe RA, Ma J, Scarborough P, Biagini C, Fiedorek FT, Travlos GS, Parker C and Zeldin DC. (1998) Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism. Mol Pharmacol, 54, 504-13.]
  16. Chen J, Capdevila JH, Zeldin DC and Rosenberg RL. (1999) Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids. Mol Pharmacol, 55, 288-95. [Abstract Chen J, Capdevila JH, Zeldin DC and Rosenberg RL. (1999) Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids. Mol Pharmacol, 55, 288-95.] [Full Text Chen J, Capdevila JH, Zeldin DC and Rosenberg RL. (1999) Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids. Mol Pharmacol, 55, 288-95.] [PDF Chen J, Capdevila JH, Zeldin DC and Rosenberg RL. (1999) Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids. Mol Pharmacol, 55, 288-95.]
  17. Ma J, Qu W, Scarborough PE, Tomer KB, Moomaw CR, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (1999) Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J Biol Chem, 274, 17777-88. [Abstract Ma J, Qu W, Scarborough PE, Tomer KB, Moomaw CR, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (1999) Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J Biol Chem, 274, 17777-88.] [Full Text Ma J, Qu W, Scarborough PE, Tomer KB, Moomaw CR, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (1999) Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J Biol Chem, 274, 17777-88.] [PDF Ma J, Qu W, Scarborough PE, Tomer KB, Moomaw CR, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (1999) Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J Biol Chem, 274, 17777-88.]
  18. Node K, Huo Y, Ruan X, Yang B, Spiecker M, Ley K, Zeldin DC and Liao JK. (1999) Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science, 285, 1276-9. [Abstract Node K, Huo Y, Ruan X, Yang B, Spiecker M, Ley K, Zeldin DC and Liao JK. (1999) Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science, 285, 1276-9.]
  19. Scarborough PE, Ma J, Qu W and Zeldin DC. (1999) P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues. Drug Metab Rev, 31, 205-34. [Abstract Scarborough PE, Ma J, Qu W and Zeldin DC. (1999) P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues. Drug Metab Rev, 31, 205-34.]
  20. Moran JH, Mitchell LA, Bradbury JA, Qu W, Zeldin DC, Schnellmann RG and Grant DF. (2000) Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. Toxicol Appl Pharmacol, 168, 268-79. [Abstract Moran JH, Mitchell LA, Bradbury JA, Qu W, Zeldin DC, Schnellmann RG and Grant DF. (2000) Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. Toxicol Appl Pharmacol, 168, 268-79.]
  21. Oleksiak MF, Wu S, Parker C, Karchner SI, Stegeman JJ and Zeldin DC. (2000) Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns. J Biol Chem, 275, 2312-21. [Abstract Oleksiak MF, Wu S, Parker C, Karchner SI, Stegeman JJ and Zeldin DC. (2000) Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns. J Biol Chem, 275, 2312-21.] [Full Text Oleksiak MF, Wu S, Parker C, Karchner SI, Stegeman JJ and Zeldin DC. (2000) Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns. J Biol Chem, 275, 2312-21.] [PDF Oleksiak MF, Wu S, Parker C, Karchner SI, Stegeman JJ and Zeldin DC. (2000) Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns. J Biol Chem, 275, 2312-21.]
  22. Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC and Goldstein JA. (2000) CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. Mol Pharmacol, 58, 279-87. [Abstract Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC and Goldstein JA. (2000) CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. Mol Pharmacol, 58, 279-87.] [Full Text Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC and Goldstein JA. (2000) CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. Mol Pharmacol, 58, 279-87.] [PDF Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC and Goldstein JA. (2000) CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. Mol Pharmacol, 58, 279-87.]
  23. Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC and Kroetz DL. (2000) Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res, 87, 992-8. [Abstract Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC and Kroetz DL. (2000) Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res, 87, 992-8.] [Full Text Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC and Kroetz DL. (2000) Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res, 87, 992-8.] [PDF Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC and Kroetz DL. (2000) Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res, 87, 992-8.]
  24. Zhu D, Bousamra M, 2nd, Zeldin DC, Falck JR, Townsley M, Harder DR, Roman RJ and Jacobs ER. (2000) Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. Am J Physiol Lung Cell Mol Physiol, 278, L335-43. [Abstract Zhu D, Bousamra M, 2nd, Zeldin DC, Falck JR, Townsley M, Harder DR, Roman RJ and Jacobs ER. (2000) Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. Am J Physiol Lung Cell Mol Physiol, 278, L335-43.]
  25. Dai D, Zeldin DC, Blaisdell JA, Chanas B, Coulter SJ, Ghanayem BI and Goldstein JA. (2001) Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics, 11, 597-607. [Abstract Dai D, Zeldin DC, Blaisdell JA, Chanas B, Coulter SJ, Ghanayem BI and Goldstein JA. (2001) Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics, 11, 597-607.]
  26. Jacobs ER and Zeldin DC. (2001) The lung HETEs (and EETs) up. Am J Physiol Heart Circ Physiol, 280, H1-H10 [Abstract Jacobs ER and Zeldin DC. (2001) The lung HETEs (and EETs) up. Am J Physiol Heart Circ Physiol, 280, H1-H10] [Full Text Jacobs ER and Zeldin DC. (2001) The lung HETEs (and EETs) up. Am J Physiol Heart Circ Physiol, 280, H1-H10]
  27. Node K, Ruan XL, Dai J, Yang SX, Graham L, Zeldin DC and Liao JK. (2001) Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem, 276, 15983-9. [Abstract Node K, Ruan XL, Dai J, Yang SX, Graham L, Zeldin DC and Liao JK. (2001) Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem, 276, 15983-9.] [Full Text Node K, Ruan XL, Dai J, Yang SX, Graham L, Zeldin DC and Liao JK. (2001) Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem, 276, 15983-9.] [PDF Node K, Ruan XL, Dai J, Yang SX, Graham L, Zeldin DC and Liao JK. (2001) Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem, 276, 15983-9.]
  28. Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL and Zeldin DC. (2001) Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. J Biol Chem, 276, 25467-79. [Abstract Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL and Zeldin DC. (2001) Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. J Biol Chem, 276, 25467-79.] [Full Text Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL and Zeldin DC. (2001) Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. J Biol Chem, 276, 25467-79.] [PDF Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL and Zeldin DC. (2001) Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. J Biol Chem, 276, 25467-79.]
  29. Tsao CC, Coulter SJ, Chien A, Luo G, Clayton NP, Maronpot R, Goldstein JA and Zeldin DC. (2001) Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products. J Pharmacol Exp Ther, 299, 39-47. [Abstract Tsao CC, Coulter SJ, Chien A, Luo G, Clayton NP, Maronpot R, Goldstein JA and Zeldin DC. (2001) Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products. J Pharmacol Exp Ther, 299, 39-47.]
  30. Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK and Zeldin DC. (2001) Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol, 60, 310-20. [Abstract Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK and Zeldin DC. (2001) Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol, 60, 310-20.] [Full Text Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK and Zeldin DC. (2001) Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol, 60, 310-20.] [PDF Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK and Zeldin DC. (2001) Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol, 60, 310-20.]
  31. Zeldin DC. (2001) Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem, 276, 36059-62. [Abstract Zeldin DC. (2001) Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem, 276, 36059-62.] [Full Text Zeldin DC. (2001) Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem, 276, 36059-62.] [PDF Zeldin DC. (2001) Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem, 276, 36059-62.]
  32. Zeldin DC, Wohlford-Lenane C, Chulada P, Bradbury JA, Scarborough PE, Roggli V, Langenbach R and Schwartz DA. (2001) Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol, 25, 457-65. [Abstract Zeldin DC, Wohlford-Lenane C, Chulada P, Bradbury JA, Scarborough PE, Roggli V, Langenbach R and Schwartz DA. (2001) Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol, 25, 457-65.]
  33. King LM, Ma J, Srettabunjong S, Graves J, Bradbury JA, Li L, Spiecker M, Liao JK, Mohrenweiser H and Zeldin DC. (2002) Cloning of CYP2J2 gene and identification of functional polymorphisms. Mol Pharmacol, 61, 840-52. [Abstract King LM, Ma J, Srettabunjong S, Graves J, Bradbury JA, Li L, Spiecker M, Liao JK, Mohrenweiser H and Zeldin DC. (2002) Cloning of CYP2J2 gene and identification of functional polymorphisms. Mol Pharmacol, 61, 840-52.]
  34. Kroetz DL and Zeldin DC. (2002) Cytochrome P450 pathways of arachidonic acid metabolism. Curr Opin Lipidol, 13, 273-83. [Abstract Kroetz DL and Zeldin DC. (2002) Cytochrome P450 pathways of arachidonic acid metabolism. Curr Opin Lipidol, 13, 273-83.]
  35. Ma J, Bradbury JA, King L, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (2002) Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform. Biochem Pharmacol, 64, 1447-60. [Abstract Ma J, Bradbury JA, King L, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (2002) Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform. Biochem Pharmacol, 64, 1447-60.] [Full Text Ma J, Bradbury JA, King L, Maronpot R, Davis LS, Breyer MD and Zeldin DC. (2002) Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform. Biochem Pharmacol, 64, 1447-60.]
  36. Zeldin DC. (2002) The 5-lipoxygenase pathway: a new therapeutic target for the treatment of pulmonary fibrosis. Am J Respir Crit Care Med, 165, 146-7. [Abstract Zeldin DC. (2002) The 5-lipoxygenase pathway: a new therapeutic target for the treatment of pulmonary fibrosis. Am J Respir Crit Care Med, 165, 146-7.]
  37. Wang H, Lin L, Jiang J, Wang Y, Lu ZY, Bradbury JA, Lih FB, Wang DW and Zeldin DC. (2003) Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways. J Pharmacol Exp Ther, 307, 753-64. [Abstract Wang H, Lin L, Jiang J, Wang Y, Lu ZY, Bradbury JA, Lih FB, Wang DW and Zeldin DC. (2003) Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways. J Pharmacol Exp Ther, 307, 753-64.] [Full Text Wang H, Lin L, Jiang J, Wang Y, Lu ZY, Bradbury JA, Lih FB, Wang DW and Zeldin DC. (2003) Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways. J Pharmacol Exp Ther, 307, 753-64.] [PDF Wang H, Lin L, Jiang J, Wang Y, Lu ZY, Bradbury JA, Lih FB, Wang DW and Zeldin DC. (2003) Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways. J Pharmacol Exp Ther, 307, 753-64.]
  38. DeLozier TC, Tsao CC, Coulter SJ, Foley J, Bradbury JA, Zeldin DC and Goldstein JA. (2004) CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J Pharmacol Exp Ther, 310, 845-54. [Abstract DeLozier TC, Tsao CC, Coulter SJ, Foley J, Bradbury JA, Zeldin DC and Goldstein JA. (2004) CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J Pharmacol Exp Ther, 310, 845-54.] [Full Text DeLozier TC, Tsao CC, Coulter SJ, Foley J, Bradbury JA, Zeldin DC and Goldstein JA. (2004) CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J Pharmacol Exp Ther, 310, 845-54.] [PDF DeLozier TC, Tsao CC, Coulter SJ, Foley J, Bradbury JA, Zeldin DC and Goldstein JA. (2004) CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J Pharmacol Exp Ther, 310, 845-54.]
  39. Ma J, Graves J, Bradbury JA, Zhao Y, Swope DL, King L, Qu W, Clark J, Myers P, Walker V, Lindzey J, Korach KS and Zeldin DC. (2004) Regulation of mouse renal CYP2J5 expression by sex hormones. Mol Pharmacol, 65, 730-43 [Abstract Ma J, Graves J, Bradbury JA, Zhao Y, Swope DL, King L, Qu W, Clark J, Myers P, Walker V, Lindzey J, Korach KS and Zeldin DC. (2004) Regulation of mouse renal CYP2J5 expression by sex hormones. Mol Pharmacol, 65, 730-43] [Full Text Ma J, Graves J, Bradbury JA, Zhao Y, Swope DL, King L, Qu W, Clark J, Myers P, Walker V, Lindzey J, Korach KS and Zeldin DC. (2004) Regulation of mouse renal CYP2J5 expression by sex hormones. Mol Pharmacol, 65, 730-43] [PDF Ma J, Graves J, Bradbury JA, Zhao Y, Swope DL, King L, Qu W, Clark J, Myers P, Walker V, Lindzey J, Korach KS and Zeldin DC. (2004) Regulation of mouse renal CYP2J5 expression by sex hormones. Mol Pharmacol, 65, 730-43]
  40. Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM and Nebert DW. (2004) Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics, 14, 1-18. [Abstract Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM and Nebert DW. (2004) Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics, 14, 1-18.]
  41. Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E and Zeldin DC. (2004) Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res, 95, 506-14. [Abstract Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E and Zeldin DC. (2004) Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res, 95, 506-14.] [Full Text Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E and Zeldin DC. (2004) Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res, 95, 506-14.] [PDF Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E and Zeldin DC. (2004) Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res, 95, 506-14.]
  42. Spiecker M, Darius H, Hankeln T, Soufi M, Sattler AM, Schaefer JR, Node K, Borgel J, Mugge A, Lindpaintner K, Huesing A, Maisch B, Zeldin DC and Liao JK. (2004) Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation, 110, 2132-6. [Abstract Spiecker M, Darius H, Hankeln T, Soufi M, Sattler AM, Schaefer JR, Node K, Borgel J, Mugge A, Lindpaintner K, Huesing A, Maisch B, Zeldin DC and Liao JK. (2004) Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation, 110, 2132-6.] [Full Text Spiecker M, Darius H, Hankeln T, Soufi M, Sattler AM, Schaefer JR, Node K, Borgel J, Mugge A, Lindpaintner K, Huesing A, Maisch B, Zeldin DC and Liao JK. (2004) Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation, 110, 2132-6.]
  43. Wang H, Zhao Y, Bradbury JA, Graves JP, Foley J, Blaisdell JA, Goldstein JA and Zeldin DC. (2004) Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol, 65, 1148-58. [Abstract Wang H, Zhao Y, Bradbury JA, Graves JP, Foley J, Blaisdell JA, Goldstein JA and Zeldin DC. (2004) Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol, 65, 1148-58.] [Full Text Wang H, Zhao Y, Bradbury JA, Graves JP, Foley J, Blaisdell JA, Goldstein JA and Zeldin DC. (2004) Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol, 65, 1148-58.] [PDF Wang H, Zhao Y, Bradbury JA, Graves JP, Foley J, Blaisdell JA, Goldstein JA and Zeldin DC. (2004) Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol, 65, 1148-58.]
  44. Xiao YF, Ke Q, Seubert JM, Bradbury JA, Graves J, Degraff LM, Falck JR, Krausz K, Gelboin HV, Morgan JP and Zeldin DC. (2004) Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. Mol Pharmacol, 66, 1607-16. [Abstract Xiao YF, Ke Q, Seubert JM, Bradbury JA, Graves J, Degraff LM, Falck JR, Krausz K, Gelboin HV, Morgan JP and Zeldin DC. (2004) Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. Mol Pharmacol, 66, 1607-16.] [Full Text Xiao YF, Ke Q, Seubert JM, Bradbury JA, Graves J, Degraff LM, Falck JR, Krausz K, Gelboin HV, Morgan JP and Zeldin DC. (2004) Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. Mol Pharmacol, 66, 1607-16.] [PDF Xiao YF, Ke Q, Seubert JM, Bradbury JA, Graves J, Degraff LM, Falck JR, Krausz K, Gelboin HV, Morgan JP and Zeldin DC. (2004) Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. Mol Pharmacol, 66, 1607-16.]
  45. Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC and Boerwinkle E. (2005) The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet, 14, 2829-37. [Abstract Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC and Boerwinkle E. (2005) The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet, 14, 2829-37.] [Full Text Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC and Boerwinkle E. (2005) The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet, 14, 2829-37.]
  46. Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC and Wang DW. (2005) Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res, 65, 4707-15. [Abstract Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC and Wang DW. (2005) Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res, 65, 4707-15.] [Full Text Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC and Wang DW. (2005) Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res, 65, 4707-15.] [PDF Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC and Wang DW. (2005) Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res, 65, 4707-15.]
  47. King LM, Gainer JV, David GL, Dai D, Goldstein JA, Brown NJ and Zeldin DC. (2005) Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension. Pharmacogenet Genomics, 15, 7-13. [Abstract King LM, Gainer JV, David GL, Dai D, Goldstein JA, Brown NJ and Zeldin DC. (2005) Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension. Pharmacogenet Genomics, 15, 7-13.]
  48. Seubert JM, Xu F, Graves JP, Collins JB, Sieber SO, Paules RS, Kroetz DL and Zeldin DC. (2005) Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats. Am J Physiol Renal Physiol, 289, F552-61. [Abstract Seubert JM, Xu F, Graves JP, Collins JB, Sieber SO, Paules RS, Kroetz DL and Zeldin DC. (2005) Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats. Am J Physiol Renal Physiol, 289, F552-61.]
  49. Wang Y, Wei X, Xiao X, Hui R, Card JW, Carey MA, Wang DW and Zeldin DC. (2005) Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. J Pharmacol Exp Ther, 314, 522-32. [Abstract Wang Y, Wei X, Xiao X, Hui R, Card JW, Carey MA, Wang DW and Zeldin DC. (2005) Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. J Pharmacol Exp Ther, 314, 522-32.] [Full Text Wang Y, Wei X, Xiao X, Hui R, Card JW, Carey MA, Wang DW and Zeldin DC. (2005) Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. J Pharmacol Exp Ther, 314, 522-32.] [PDF Wang Y, Wei X, Xiao X, Hui R, Card JW, Carey MA, Wang DW and Zeldin DC. (2005) Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. J Pharmacol Exp Ther, 314, 522-32.]
  50. Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM and Mansuy D. (2006) Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. Bioorg Med Chem Lett, 16, 2777-80. [Abstract Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM and Mansuy D. (2006) Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. Bioorg Med Chem Lett, 16, 2777-80.] [Full Text Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM and Mansuy D. (2006) Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. Bioorg Med Chem Lett, 16, 2777-80.] [PDF Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM and Mansuy D. (2006) Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. Bioorg Med Chem Lett, 16, 2777-80.]
  51. Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study. Hum Mol Genet. 2006 May 15;15(10):1640-1649. [Abstract Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study. Hum Mol Genet. 2006 May 15;15(10):1640-1649.] [Full Text Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study. Hum Mol Genet. 2006 May 15;15(10):1640-1649.] [PDF Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study. Hum Mol Genet. 2006 May 15;15(10):1640-1649.]
  52. Paine MF, Hart HL, Lundington SS, Haining RL, Rettie AE, Zeldin D.C. The human intestinal cytochrome P450 Pie. Drug Metab Dispos. 2006 May;34(5):880-886. [Abstract Paine MF, Hart HL, Lundington SS, Haining RL, Rettie AE, Zeldin D.C. The human intestinal cytochrome P450 Pie. Drug Metab Dispos. 2006 May;34(5):880-886.] [Full Text Paine MF, Hart HL, Lundington SS, Haining RL, Rettie AE, Zeldin D.C. The human intestinal cytochrome P450 Pie. Drug Metab Dispos. 2006 May;34(5):880-886.] [PDF Paine MF, Hart HL, Lundington SS, Haining RL, Rettie AE, Zeldin D.C. The human intestinal cytochrome P450 Pie. Drug Metab Dispos. 2006 May;34(5):880-886.]
  53. Seubert JM, Sinal CJ, Graves JP, DeGraff LM, Bradbury JS, Lee CR, Goralski KB, Carey MA, Lauria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res. 2006 Aug 18;99(4):442-450. [Abstract Seubert JM, Sinal CJ, Graves JP, DeGraff LM, Bradbury JS, Lee CR, Goralski KB, Carey MA, Lauria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res. 2006 Aug 18;99(4):442-450.] [Full Text Seubert JM, Sinal CJ, Graves JP, DeGraff LM, Bradbury JS, Lee CR, Goralski KB, Carey MA, Lauria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res. 2006 Aug 18;99(4):442-450.] [PDF Seubert JM, Sinal CJ, Graves JP, DeGraff LM, Bradbury JS, Lee CR, Goralski KB, Carey MA, Lauria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res. 2006 Aug 18;99(4):442-450.]
  54. DeLozier TC, Kissling GE, Coulter SJ, Dai D, Foley JF, Bradbury JA, Murphy E, Steenbergen C, Zeldin DC, Goldstein JA. Detection of human CYP2C8, CYP2C9 and CYP2J2 in cardiovascular tissues. Drug Metabolism and Disposition 2007; 35:682-688. [Abstract DeLozier TC, Kissling GE, Coulter SJ, Dai D, Foley JF, Bradbury JA, Murphy E, Steenbergen C, Zeldin DC, Goldstein JA. Detection of human CYP2C8, CYP2C9 and CYP2J2 in cardiovascular tissues. Drug Metabolism and Disposition 2007; 35:682-688.]
  55. Jiang JG, Ning YG, Chen C, Ma D, Liu ZJ, Yang S, Zhou J, Xiao X, Zhang XA, Edin ML, Card JW, Wang J, Zeldin DC and Wang DW. (2007) Cytochrome p450 epoxygenase promotes human cancer metastasis. Cancer Res, 67, 6665-74. [Abstract Jiang JG, Ning YG, Chen C, Ma D, Liu ZJ, Yang S, Zhou J, Xiao X, Zhang XA, Edin ML, Card JW, Wang J, Zeldin DC and Wang DW. (2007) Cytochrome p450 epoxygenase promotes human cancer metastasis. Cancer Res, 67, 6665-74.]
  56. Ke Q, Xiao Y-F, Bradvury JA, Graves JP, DeGraff LM, Seubert JM, Zeldin DC. Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice. Mol Pharmacol. 2007 Oct;72(4):11063-73. [Abstract Ke Q, Xiao Y-F, Bradvury JA, Graves JP, DeGraff LM, Seubert JM, Zeldin DC. Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice. Mol Pharmacol. 2007 Oct;72(4):11063-73.] [Full Text Ke Q, Xiao Y-F, Bradvury JA, Graves JP, DeGraff LM, Seubert JM, Zeldin DC. Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice. Mol Pharmacol. 2007 Oct;72(4):11063-73.] [PDF Ke Q, Xiao Y-F, Bradvury JA, Graves JP, DeGraff LM, Seubert JM, Zeldin DC. Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice. Mol Pharmacol. 2007 Oct;72(4):11063-73.]
  57. Seubert JM, Zeldin DC, Nithipatikom K and Gross GJ. (2007) Role of epoxyeicosatrienoic acids in protecting the myocardium following; ischemia/reperfusion injury. Prostaglandins Other Lipid Mediat, 82:50-9. [Abstract Seubert JM, Zeldin DC, Nithipatikom K and Gross GJ. (2007) Role of epoxyeicosatrienoic acids in protecting the myocardium following; ischemia/reperfusion injury. Prostaglandins Other Lipid Mediat, 82:50-9.]
  58. Yang S, Lin L, Chen J-X, Lee CR, Seubert JM, Wang Y, Wang H, Chao Z-R, Tao D-D, Gong J-P, Lu Z-Y, Wang DW, Zeldin DC. (2007) Cytochrome P450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-α via MAPK and PI3K/Akt signaling pathways. AmericanJ Physiol Heart Circ Physiol. 293:H142-51. [Abstract Yang S, Lin L, Chen J-X, Lee CR, Seubert JM, Wang Y, Wang H, Chao Z-R, Tao D-D, Gong J-P, Lu Z-Y, Wang DW, Zeldin DC. (2007) Cytochrome P450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-α via MAPK and PI3K/Akt signaling pathways. AmericanJ Physiol Heart Circ Physiol. 293:H142-51.] [Full Text Yang S, Lin L, Chen J-X, Lee CR, Seubert JM, Wang Y, Wang H, Chao Z-R, Tao D-D, Gong J-P, Lu Z-Y, Wang DW, Zeldin DC. (2007) Cytochrome P450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-α via MAPK and PI3K/Akt signaling pathways. AmericanJ Physiol Heart Circ Physiol. 293:H142-51.]
  59. Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2) CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 17:349-58. [Abstract Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2) CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 17:349-58.] [Full Text Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2) CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 17:349-58.] [PDF Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2) CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 17:349-58.]
  60. Athirakul K, Bradbury JA, Graves JP, DeGraff LM, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, Korach KS, Coffman TM and Zeldin DC. (2008) Increased blood pressure in mice lacking cytochrome P450 2J5. Faseb J, 22:4096-108. [Abstract Athirakul K, Bradbury JA, Graves JP, DeGraff LM, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, Korach KS, Coffman TM and Zeldin DC. (2008) Increased blood pressure in mice lacking cytochrome P450 2J5. Faseb J, 22:4096-108.]
  61. Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther. 2009 Jun;329(3):908-18. [Abstract Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther. 2009 Jun;329(3):908-18.] [Full Text Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther. 2009 Jun;329(3):908-18.] [PDF Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther. 2009 Jun;329(3):908-18.]
  62. Zhang Y, El-Sikhry H, Chaudhary K, Batchu SN, Shayeqanpour A, Jukar TO, Bradbury JA, Graves JP, DeGraff LM, Myers PH, Rouse DC, Foley J, Nyska A, Zeldin DC, Seubert JM. (2009) Overexpression of CYP2J2 provides protection against doxorubicin induced cardiotoxicity. Am J Physiol Heart Circ Physiol. 297:H37-46. [Abstract Zhang Y, El-Sikhry H, Chaudhary K, Batchu SN, Shayeqanpour A, Jukar TO, Bradbury JA, Graves JP, DeGraff LM, Myers PH, Rouse DC, Foley J, Nyska A, Zeldin DC, Seubert JM. (2009) Overexpression of CYP2J2 provides protection against doxorubicin induced cardiotoxicity. Am J Physiol Heart Circ Physiol. 297:H37-46.] [Full Text Zhang Y, El-Sikhry H, Chaudhary K, Batchu SN, Shayeqanpour A, Jukar TO, Bradbury JA, Graves JP, DeGraff LM, Myers PH, Rouse DC, Foley J, Nyska A, Zeldin DC, Seubert JM. (2009) Overexpression of CYP2J2 provides protection against doxorubicin induced cardiotoxicity. Am J Physiol Heart Circ Physiol. 297:H37-46.]
  63. Ding H, Zhang L, Wu B, Wang Q, Hui R, Wang W, Dackor RT, Kissling GE, Zeldin DC, Wang DW. Association of common variants of CYP4A11 and CYP4F2 with stroke in the Chinese Han population. Pharmacogenetics and Genomics 2010; 20:187-194. [Abstract Ding H, Zhang L, Wu B, Wang Q, Hui R, Wang W, Dackor RT, Kissling GE, Zeldin DC, Wang DW. Association of common variants of CYP4A11 and CYP4F2 with stroke in the Chinese Han population. Pharmacogenetics and Genomics 2010; 20:187-194.]
  64. Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow L, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. (2010) Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. The FASEB journal. 24:3770-81. [Abstract Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow L, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. (2010) Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. The FASEB journal. 24:3770-81.] [Full Text Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow L, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. (2010) Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. The FASEB journal. 24:3770-81.] [PDF Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow L, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. (2010) Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. The FASEB journal. 24:3770-81.]
  65. Dackor RT, Cheng J, Voltz JW, Card JW, Ferguson CD, Garrett RC, Bradbury JA, DeGraff LM, Lih FB, Tomer KB, Flake GP, Travlos GS, Ramsey RW, Jr., Edin ML, Morgan DL and Zeldin DC. (2011) Prostaglandin E(2) protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction. Am J Physiol Lung Cell Mol Physiol, 301:L645-55. [Abstract Dackor RT, Cheng J, Voltz JW, Card JW, Ferguson CD, Garrett RC, Bradbury JA, DeGraff LM, Lih FB, Tomer KB, Flake GP, Travlos GS, Ramsey RW, Jr., Edin ML, Morgan DL and Zeldin DC. (2011) Prostaglandin E(2) protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction. Am J Physiol Lung Cell Mol Physiol, 301:L645-55.]
  66. Deng, Y., M.L. Edin, K.N. Theken, R.N. Schuck, G.P. Flake, M.A. Kannon, L.M. DeGraff, F.B. Lih, J. Foley, J.A. Bradbury, J.P. Graves, K.B. Tomer, J.R. Falck, D.C. Zeldin, C.R. Lee. (2011) Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice. FASEB J, 25:703-713, 2011. [Abstract Deng, Y., M.L. Edin, K.N. Theken, R.N. Schuck, G.P. Flake, M.A. Kannon, L.M. DeGraff, F.B. Lih, J. Foley, J.A. Bradbury, J.P. Graves, K.B. Tomer, J.R. Falck, D.C. Zeldin, C.R. Lee. (2011) Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice. FASEB J, 25:703-713, 2011.]
  67. Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JA, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC. (2011) Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 25:3436-3447. [Abstract Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JA, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC. (2011) Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 25:3436-3447.] [Full Text Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JA, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC. (2011) Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 25:3436-3447.]
  68. Panigrahy D, Greene ER, Pozzi A, Wang DW and Zeldin DC. (2011) EET signaling in cancer. Cancer Metastasis Rev, 30:525-40. [Abstract Panigrahy D, Greene ER, Pozzi A, Wang DW and Zeldin DC. (2011) EET signaling in cancer. Cancer Metastasis Rev, 30:525-40.]
  69. Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC and Arand M. (2012) EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. J Lipid Res, 53:2038-45. [Abstract Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC and Arand M. (2012) EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. J Lipid Res, 53:2038-45.]
  70. Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnes CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW and Zeldin DC. (2012) Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest, 122:178-91. [Abstract Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnes CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW and Zeldin DC. (2012) Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest, 122:178-91.]
  71. Theken KN, Schuck RN, Edin ML, Tran B, Ellis K, Bass A, Lih FB, Tomer KB, Poloyac SM, Wu MC, Hinderliter AL, Zeldin DC, Stouffer GA and Lee CR. (2012) Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. Atherosclerosis, 222:530-6. [Abstract Theken KN, Schuck RN, Edin ML, Tran B, Ellis K, Bass A, Lih FB, Tomer KB, Poloyac SM, Wu MC, Hinderliter AL, Zeldin DC, Stouffer GA and Lee CR. (2012) Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. Atherosclerosis, 222:530-6.]
  72. Graves JP, Edin ML, Bradbury JA, Gruzdev A, Cheng J , Lih FB , Masinde TA, Qu W, Clayton NP, Morrison JP, Tomer KB, Zeldin DC. (2013) Characterization of Four New Mouse Cytochrome P450 Enzymes of the CYP2J Subfamily. Drug Meta Dispos, 41:763-773. [Abstract Graves JP, Edin ML, Bradbury JA, Gruzdev A, Cheng J , Lih FB , Masinde TA, Qu W, Clayton NP, Morrison JP, Tomer KB, Zeldin DC. (2013) Characterization of Four New Mouse Cytochrome P450 Enzymes of the CYP2J Subfamily. Drug Meta Dispos, 41:763-773.]
  73. Klett EL, Chen S, Edin ML, Li LO, Ilkayeva O, Zeldin DC, Newgard CB and Coleman RA. (2013) Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. J Biol Chem, 288, 21618-29. [Abstract Klett EL, Chen S, Edin ML, Li LO, Ilkayeva O, Zeldin DC, Newgard CB and Coleman RA. (2013) Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. J Biol Chem, 288, 21618-29.]
  74. Nayeem MA, Pradhan I, Mustafa SJ, Morisseau C, Falck JR and Zeldin DC. (2013) Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARgamma. Am J Physiol Regul Integr Comp Physiol, 304:R23-32. [Abstract Nayeem MA, Pradhan I, Mustafa SJ, Morisseau C, Falck JR and Zeldin DC. (2013) Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARgamma. Am J Physiol Regul Integr Comp Physiol, 304:R23-32.]
  75. Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC and Kieran MW. (2013) Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci, 110:13528-33. [Abstract Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC and Kieran MW. (2013) Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci, 110:13528-33.]
  76. Schuck RN, Theken KN, Edin ML, Caughey M, Bass A, Ellis K, Tran B, Steele S, Simmons BP, Lih FB, Tomer KB, Wu MC, Hinderliter AL, Stouffer GA, Zeldin DC and Lee CR. (2013) Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients. Atherosclerosis, 227:442-8. [Abstract Schuck RN, Theken KN, Edin ML, Caughey M, Bass A, Ellis K, Tran B, Steele S, Simmons BP, Lih FB, Tomer KB, Wu MC, Hinderliter AL, Stouffer GA, Zeldin DC and Lee CR. (2013) Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients. Atherosclerosis, 227:442-8.]
  77. Strauss KI, Gruzdev A and Zeldin DC. (2013) Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury. Prostaglandins Other Lipid Mediat, 104-105:18-24. [Abstract Strauss KI, Gruzdev A and Zeldin DC. (2013) Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury. Prostaglandins Other Lipid Mediat, 104-105:18-24.]
  78. Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, Schwartzman ML, Zeldin DC. Vascular characterization of mice with endothelial expression of cytochrome P450 4F2. FASEB J, 28:2915-2931. [Abstract Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, Schwartzman ML, Zeldin DC. Vascular characterization of mice with endothelial expression of cytochrome P450 4F2. FASEB J, 28:2915-2931.]
  79. Wang WH, Zhang C, Lin DH, Wang L, Graves JP, Zeldin DC, Capdevila JH. (2014) Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect. American J Physiol. Renal Physiol, 307:F453-F460. [Abstract Wang WH, Zhang C, Lin DH, Wang L, Graves JP, Zeldin DC, Capdevila JH. (2014) Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect. American J Physiol. Renal Physiol, 307:F453-F460.]
  80. Wang X, Ni L, Yang L, Duan Q, Chen C, Edin ML, Zeldin DC, Wang DW. (2014) CYP2J2-Derived Epoxyeicosatrienoic Acids Suppress Endoplasmic Reticulum Stress in Heart Failure. J Lipid Research, 85:105-115. [Abstract Wang X, Ni L, Yang L, Duan Q, Chen C, Edin ML, Zeldin DC, Wang DW. (2014) CYP2J2-Derived Epoxyeicosatrienoic Acids Suppress Endoplasmic Reticulum Stress in Heart Failure. J Lipid Research, 85:105-115.]
  81. Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Li H, House JS, Hoopes SL, Edin ML and Zeldin DC. (2015) Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation. Drug Metab Dispos, 43:1169-80. [Abstract Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Li H, House JS, Hoopes SL, Edin ML and Zeldin DC. (2015) Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation. Drug Metab Dispos, 43:1169-80.]
  82. Hoopes SL, Garcia V, Edin ML, Schwartzman ML and Zeldin DC. (2015) Vascular actions of 20-HETE. Prostaglandins Other Lipid Mediat 120:9-16.  [Abstract Hoopes SL, Garcia V, Edin ML, Schwartzman ML and Zeldin DC. (2015) Vascular actions of 20-HETE. Prostaglandins Other Lipid Mediat 120:9-16. ]
  83. Kirkby NS, Reed DM, Edin ML, Rauzi F, Mataragka S, Vojnovic I, Bishop-Bailey D, Milne GL, Longhurst H, Zeldin DC, Mitchell JA and Warner TD. (2015) Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation. Circulation 29:4568-4578 [Abstract Kirkby NS, Reed DM, Edin ML, Rauzi F, Mataragka S, Vojnovic I, Bishop-Bailey D, Milne GL, Longhurst H, Zeldin DC, Mitchell JA and Warner TD. (2015) Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation. Circulation 29:4568-4578]
  84. Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC and Zon LI. (2015) Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature, 523:468-71. [Abstract Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC and Zon LI. (2015) Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature, 523:468-71.]
  85. Gilroy DW, Edin ML, De Maeyer RP, Bystrom J, Newson J, Lih FB, Stables M, Zeldin DC and Bishop-Bailey D. (2016) CYP450-derived oxylipins mediate inflammatory resolution. Proc Natl Acad Sci U S A, 113, E3240-9. [Abstract Gilroy DW, Edin ML, De Maeyer RP, Bystrom J, Newson J, Lih FB, Stables M, Zeldin DC and Bishop-Bailey D. (2016) CYP450-derived oxylipins mediate inflammatory resolution. Proc Natl Acad Sci U S A, 113, E3240-9.]
  86. Jia J, Davis CM, Zhang W, Edin ML, Jouihan S, Jia T, Bradbury JA, Graves JP, DeGraff LM, Lee CR, Ronnekleiv O, Wang R, Xu Y, Zeldin DC and Alkayed NJ. (2016) Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium. Exp Neurol, 279:75-85. [Abstract Jia J, Davis CM, Zhang W, Edin ML, Jouihan S, Jia T, Bradbury JA, Graves JP, DeGraff LM, Lee CR, Ronnekleiv O, Wang R, Xu Y, Zeldin DC and Alkayed NJ. (2016) Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium. Exp Neurol, 279:75-85.] 
  87. Oni-Orisan A, Edin ML, Lee JA, Wells MA, Christensen ES, Vendrov KC, Lih FB, Tomer KB, Bai X, Taylor JM, Stouffer GA, Zeldin DC and Lee CR. (2016) Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study. J Lipid Res, 57, 109-19. [Abstract Oni-Orisan A, Edin ML, Lee JA, Wells MA, Christensen ES, Vendrov KC, Lih FB, Tomer KB, Bai X, Taylor JM, Stouffer GA, Zeldin DC and Lee CR. (2016) Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study. J Lipid Res, 57, 109-19.]
  88. Garcia V, Gilani A, Shkolnik B, Pandey V, Zhang FF, Dakarapu R, Gandham SK, Reddy NR, Graves JP, Gruzdev A, Zeldin DC, Capdevila JH, Falck JR and Schwartzman ML. (2017) 20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension. Circ Res, 120:1776-1788. [Abstract Garcia V, Gilani A, Shkolnik B, Pandey V, Zhang FF, Dakarapu R, Gandham SK, Reddy NR, Graves JP, Gruzdev A, Zeldin DC, Capdevila JH, Falck JR and Schwartzman ML. (2017) 20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension. Circ Res, 120:1776-1788.]
  89. Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Edin ML and Zeldin DC. (2017) Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2c Subfamily and Characterization of their Tissue Distribution. Drug Metab Dispos. [Abstract Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Edin ML and Zeldin DC. (2017) Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2c Subfamily and Characterization of their Tissue Distribution. Drug Metab Dispos.] 
  90. Hoopes SL, Gruzdev A, Edin ML, Graves JP, Bradbury JA, Flake GP, Lih FB, DeGraff LM and Zeldin DC. (2017) Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice. PLoS One, 12:e0175348. [Abstract Hoopes SL, Gruzdev A, Edin ML, Graves JP, Bradbury JA, Flake GP, Lih FB, DeGraff LM and Zeldin DC. (2017) Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice. PLoS One, 12:e0175348.]
  91. Edin ML, Hamedani BG, Gruzdev A, Graves JP, Lih FB, Arbes SJ, 3rd, Singh R, Orjuela Leon AC, Bradbury JA, DeGraff LM, Hoopes SL, Arand M, and Zeldin DC. (2018) Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia. J Biol Chem, 293:3281-92. [Abstract Edin ML, Hamedani BG, Gruzdev A, Graves JP, Lih FB, Arbes SJ, 3rd, Singh R, Orjuela Leon AC, Bradbury JA, DeGraff LM, Hoopes SL, Arand M, and Zeldin DC. (2018) Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia. J Biol Chem, 293:3281-92.]
  92. Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, and Warner TD. (2018) Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M. Circ Res. 122:555-9. [Abstract Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, and Warner TD. (2018) Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M. Circ Res. 122:555-9.]
  93. Edin ML, Zeldin DC. (2018) Commercial scale production of RvD4 opens the resolving door to new research. J Leukoc Biol, 103:991-3. [Abstract Edin ML, Zeldin DC. (2018) Commercial scale production of RvD4 opens the resolving door to new research. J Leukoc Biol, 103:991-3.]
  94. Hada M, Edin ML, Hartge P, Lih FB, (2019) Wentzensen N, Zeldin DC, and Trabert B. Prediagnostic Serum Levels of Fatty Acid Metabolites and Risk of Ovarian Cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Cancer Epidemiol Biomarkers Prev, 28:189-97. [Abstract Hada M, Edin ML, Hartge P, Lih FB, (2019) Wentzensen N, Zeldin DC, and Trabert B. Prediagnostic Serum Levels of Fatty Acid Metabolites and Risk of Ovarian Cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Cancer Epidemiol Biomarkers Prev, 28:189-97.]
  95. Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, and Zhang G. (2019) Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res, 79:1822-30. [Abstract Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, and Zhang G. (2019) Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res, 79:1822-30.]
  96. Graves JP, Bradbury JA, Gruzdev A, Li H, Duval C, Lih FB, Edin ML, Zeldin DC. 2019. Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS-induced inflammation and resolution in mice. FASEB J, doi: 10.1096/fj.201901872R [Online 5 November 2019]. [Abstract Graves JP, Bradbury JA, Gruzdev A, Li H, Duval C, Lih FB, Edin ML, Zeldin DC. 2019. Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS-induced inflammation and resolution in mice. FASEB J, doi: 10.1096/fj.201901872R [Online 5 November 2019].] 
  97. Hanif A, Edin ML, Zeldin DC, Nayeem MA. 2020. Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases. Mol Cell Biochem 465(1-2):37-51. [Abstract Hanif A, Edin ML, Zeldin DC, Nayeem MA. 2020. Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases. Mol Cell Biochem 465(1-2):37-51.] 
  98. Agba S, Hanif A, Edin ML, Zeldin DC, Nayeem MA. 2020. Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor. Front Pharmacol; doi: 10.3389/fphar.2020.00027 [Online 5 February 2020]. [Abstract Agba S, Hanif A, Edin ML, Zeldin DC, Nayeem MA. 2020. Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor. Front Pharmacol; doi: 10.3389/fphar.2020.00027 [Online 5 February 2020].] 

COX-derived Eicosanoids

  1. Boyle JE, Lindroos PM, Rice AB, Zhang L, Zeldin DC, Bonner JC. (1999) Prostaglandin-E2 counteracts interleukin-1 stimulated up-regulation of platelet-derived growth factor -receptor on rat pulmonary myofibroblasts. Am J Respir Cell Mol Biol. 20:433-40. [Abstract Boyle JE, Lindroos PM, Rice AB, Zhang L, Zeldin DC, Bonner JC. (1999) Prostaglandin-E2 counteracts interleukin-1 stimulated up-regulation of platelet-derived growth factor -receptor on rat pulmonary myofibroblasts. Am J Respir Cell Mol Biol. 20:433-40.] [Full Text Boyle JE, Lindroos PM, Rice AB, Zhang L, Zeldin DC, Bonner JC. (1999) Prostaglandin-E2 counteracts interleukin-1 stimulated up-regulation of platelet-derived growth factor -receptor on rat pulmonary myofibroblasts. Am J Respir Cell Mol Biol. 20:433-40.] [PDF Boyle JE, Lindroos PM, Rice AB, Zhang L, Zeldin DC, Bonner JC. (1999) Prostaglandin-E2 counteracts interleukin-1 stimulated up-regulation of platelet-derived growth factor -receptor on rat pulmonary myofibroblasts. Am J Respir Cell Mol Biol. 20:433-40.]
  2. Gavett SH, Madison SL, Chulada P, Scarborough PE, Qu W, Boyle JE, Tiano H, Lee CA, Langenbach R, Roggli V, Zeldin DC. (1999) Allergic lung responses are increased in PGH synthase deficient mice. J Clin Invest, 104:721-32. [Abstract Gavett SH, Madison SL, Chulada P, Scarborough PE, Qu W, Boyle JE, Tiano H, Lee CA, Langenbach R, Roggli V, Zeldin DC. (1999) Allergic lung responses are increased in PGH synthase deficient mice. J Clin Invest, 104:721-32.] [Full Text Gavett SH, Madison SL, Chulada P, Scarborough PE, Qu W, Boyle JE, Tiano H, Lee CA, Langenbach R, Roggli V, Zeldin DC. (1999) Allergic lung responses are increased in PGH synthase deficient mice. J Clin Invest, 104:721-32.] [PDF Gavett SH, Madison SL, Chulada P, Scarborough PE, Qu W, Boyle JE, Tiano H, Lee CA, Langenbach R, Roggli V, Zeldin DC. (1999) Allergic lung responses are increased in PGH synthase deficient mice. J Clin Invest, 104:721-32.]
  3. Camitta MGW, Gabel SA, Chulada PC, Bradbury AJ, Langenbach R, Zeldin DC, Murphy E. (2001) Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury, but are protected by acute preconditioning. Circulation. 104:2453-8. [Abstract Camitta MGW, Gabel SA, Chulada PC, Bradbury AJ, Langenbach R, Zeldin DC, Murphy E. (2001) Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury, but are protected by acute preconditioning. Circulation. 104:2453-8.] [Full Text Camitta MGW, Gabel SA, Chulada PC, Bradbury AJ, Langenbach R, Zeldin DC, Murphy E. (2001) Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury, but are protected by acute preconditioning. Circulation. 104:2453-8.] [PDF Camitta MGW, Gabel SA, Chulada PC, Bradbury AJ, Langenbach R, Zeldin DC, Murphy E. (2001) Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury, but are protected by acute preconditioning. Circulation. 104:2453-8.]
  4. Bonner JC, Rice A, Bradbury JA, Chulada PC, Moomaw C, Morgan D, Nyska A, Tiano HF, Zeldin DC, Langenbach R. (2002) Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. Am J Pathol. 161:459-70. [Abstract Bonner JC, Rice A, Bradbury JA, Chulada PC, Moomaw C, Morgan D, Nyska A, Tiano HF, Zeldin DC, Langenbach R. (2002) Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. Am J Pathol. 161:459-70.]
  5. Carey MA, Germolec DR, Bradbury JA, Gooch RA, Moorman MP, Flake GP, Langenbach R, Zeldin DC. (2003) Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2 -/- mice. Am J Respir Crit Care Med, 167:1509-15. [Abstract Carey MA, Germolec DR, Bradbury JA, Gooch RA, Moorman MP, Flake GP, Langenbach R, Zeldin DC. (2003) Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2 -/- mice. Am J Respir Crit Care Med, 167:1509-15.] [Full Text Carey MA, Germolec DR, Bradbury JA, Gooch RA, Moorman MP, Flake GP, Langenbach R, Zeldin DC. (2003) Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2 -/- mice. Am J Respir Crit Care Med, 167:1509-15.] [PDF Carey MA, Germolec DR, Bradbury JA, Gooch RA, Moorman MP, Flake GP, Langenbach R, Zeldin DC. (2003) Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2 -/- mice. Am J Respir Crit Care Med, 167:1509-15.]
  6. Carey MA, Germolec DR, Langenbach R and Zeldin DC. (2003) Cyclooxygenase enzymes in allergic inflammation and asthma. Prostaglandins Leukot Essent Fatty Acids, 69:157-62. [Abstract Carey MA, Germolec DR, Langenbach R and Zeldin DC. (2003) Cyclooxygenase enzymes in allergic inflammation and asthma. Prostaglandins Leukot Essent Fatty Acids, 69:157-62.]
  7. Carey MA, Bradbury JA, Langenbach R, Zeldin DC, Germolec DR. (2005) Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection. J Immunol. 175:6878-6884. [Abstract Carey MA, Bradbury JA, Langenbach R, Zeldin DC, Germolec DR. (2005) Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection. J Immunol. 175:6878-6884.] [Full Text Carey MA, Bradbury JA, Langenbach R, Zeldin DC, Germolec DR. (2005) Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection. J Immunol. 175:6878-6884.] [PDF Carey MA, Bradbury JA, Langenbach R, Zeldin DC, Germolec DR. (2005) Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection. J Immunol. 175:6878-6884.]
  8. Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC. (2006) Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation. J Immunol. 177:621-30. [Abstract Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC. (2006) Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation. J Immunol. 177:621-30.] [Full Text Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC. (2006) Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation. J Immunol. 177:621-30.] [PDF Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC. (2006) Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation. J Immunol. 177:621-30.]
  9. Card JW, Carey MA, Bradbury JA, Graves JP, Lih FB, Moorman MP, Morgan DL, DeGraff LM, Zhao Y, Foley JF, Zeldin DC. (2006) Cyclooxygenase-1 overexpression decreases basal airway responsiveness but not allergic inflammation. J Immunol. 177:4785-93. [Abstract Card JW, Carey MA, Bradbury JA, Graves JP, Lih FB, Moorman MP, Morgan DL, DeGraff LM, Zhao Y, Foley JF, Zeldin DC. (2006) Cyclooxygenase-1 overexpression decreases basal airway responsiveness but not allergic inflammation. J Immunol. 177:4785-93.] [Full Text Card JW, Carey MA, Bradbury JA, Graves JP, Lih FB, Moorman MP, Morgan DL, DeGraff LM, Zhao Y, Foley JF, Zeldin DC. (2006) Cyclooxygenase-1 overexpression decreases basal airway responsiveness but not allergic inflammation. J Immunol. 177:4785-93.] [PDF Card JW, Carey MA, Bradbury JA, Graves JP, Lih FB, Moorman MP, Morgan DL, DeGraff LM, Zhao Y, Foley JF, Zeldin DC. (2006) Cyclooxygenase-1 overexpression decreases basal airway responsiveness but not allergic inflammation. J Immunol. 177:4785-93.]
  10. Card JW, Voltz JW, Carey MA, Bradbury JA, DeGraff LM, Lih FB, Bonner JC, Morgan DL, Flake GP, Zeldin DC. (2007) Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis. Am J Respir Cell Mol Biol. 37:300-8. [Abstract Card JW, Voltz JW, Carey MA, Bradbury JA, DeGraff LM, Lih FB, Bonner JC, Morgan DL, Flake GP, Zeldin DC. (2007) Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis. Am J Respir Cell Mol Biol. 37:300-8.] [Full Text Card JW, Voltz JW, Carey MA, Bradbury JA, DeGraff LM, Lih FB, Bonner JC, Morgan DL, Flake GP, Zeldin DC. (2007) Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis. Am J Respir Cell Mol Biol. 37:300-8.] [PDF Card JW, Voltz JW, Carey MA, Bradbury JA, DeGraff LM, Lih FB, Bonner JC, Morgan DL, Flake GP, Zeldin DC. (2007) Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis. Am J Respir Cell Mol Biol. 37:300-8.]
  11. Lee CR, Bottone FG, Krahn J, Li L, Mohrenweiser H, Cook ME, Petrovich RM, Bell DA, Eling TE, Zeldin DC. (2007) Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics. 17:145-160. [Abstract Lee CR, Bottone FG, Krahn J, Li L, Mohrenweiser H, Cook ME, Petrovich RM, Bell DA, Eling TE, Zeldin DC. (2007) Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics. 17:145-160.] [Full Text Lee CR, Bottone FG, Krahn J, Li L, Mohrenweiser H, Cook ME, Petrovich RM, Bell DA, Eling TE, Zeldin DC. (2007) Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics. 17:145-160.] [PDF Lee CR, Bottone FG, Krahn J, Li L, Mohrenweiser H, Cook ME, Petrovich RM, Bell DA, Eling TE, Zeldin DC. (2007) Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics. 17:145-160.]
  12. Zeldin DC, Card JW, Carey MA, Voltz JA. (2007) Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease. J Appl Physiol. 103:1906; author reply 1909-10. [Full Text Zeldin DC, Card JW, Carey MA, Voltz JA. (2007) Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease. J Appl Physiol. 103:1906; author reply 1909-10.]
  13. Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2008) Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Clin Pharmacol Ther. 83:52-60. [Abstract Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2008) Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Clin Pharmacol Ther. 83:52-60.] [Full Text Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2008) Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Clin Pharmacol Ther. 83:52-60.] [PDF Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. (2008) Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Clin Pharmacol Ther. 83:52-60.]
  14. Card JW, Carey MA, Voltz JW, Bradbury JA, Ferguson CD, Cohen EA, Schwartz S, Flake GP, Morgan DL, Arbes SJ, Barrow DA, Barros SP, Offenbacher S, Zeldin DC. (2010) Modulation of allergic airway inflammation by the oral pathogen. Infect Immun. 78:2488-96. [Abstract Card JW, Carey MA, Voltz JW, Bradbury JA, Ferguson CD, Cohen EA, Schwartz S, Flake GP, Morgan DL, Arbes SJ, Barrow DA, Barros SP, Offenbacher S, Zeldin DC. (2010) Modulation of allergic airway inflammation by the oral pathogen. Infect Immun. 78:2488-96.] [Full Text Card JW, Carey MA, Voltz JW, Bradbury JA, Ferguson CD, Cohen EA, Schwartz S, Flake GP, Morgan DL, Arbes SJ, Barrow DA, Barros SP, Offenbacher S, Zeldin DC. (2010) Modulation of allergic airway inflammation by the oral pathogen. Infect Immun. 78:2488-96.] [PDF Card JW, Carey MA, Voltz JW, Bradbury JA, Ferguson CD, Cohen EA, Schwartz S, Flake GP, Morgan DL, Arbes SJ, Barrow DA, Barros SP, Offenbacher S, Zeldin DC. (2010) Modulation of allergic airway inflammation by the oral pathogen. Infect Immun. 78:2488-96.]
  15. Carey MA, Bradbury JA, Rebolloso YD, Graves JP, Zeldin DC and Germolec DR. (2010) Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice. PLoS One, 5:e11610. [Abstract Carey MA, Bradbury JA, Rebolloso YD, Graves JP, Zeldin DC and Germolec DR. (2010) Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice. PLoS One, 5:e11610.]
  16. Li H, Bradbury JA, Dackor RT, Edin ML, Graves JP, DeGraff LM, Wang PM, Bortner CD, Maruoka S, Lih FB, Cook DN, Tomer KB, Jetten AM and Zeldin DC. (2011) Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation. Am J Respir Crit Care Med, 184:37-49. [Abstract Li H, Bradbury JA, Dackor RT, Edin ML, Graves JP, DeGraff LM, Wang PM, Bortner CD, Maruoka S, Lih FB, Cook DN, Tomer KB, Jetten AM and Zeldin DC. (2011) Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation. Am J Respir Crit Care Med, 184:37-49.]
  17. Li H, Edin ML, Bradbury JA, Graves JP, DeGraff LM, Gruzdev A, Cheng J, Dackor RT, Wang PM, Bortner CD, Garantziotis S, Jetten AM, Zeldin DC. (2013) Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB. Am J Respir Crit Care Med 187:812-822. [Abstract Li H, Edin ML, Bradbury JA, Graves JP, DeGraff LM, Gruzdev A, Cheng J, Dackor RT, Wang PM, Bortner CD, Garantziotis S, Jetten AM, Zeldin DC. (2013) Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB. Am J Respir Crit Care Med 187:812-822.]
  18. Li H, Edin ML, Gruzdev A, Cheng J, Bradbury JA, Graves JP, DeGraff LM and Zeldin DC. (2013) Regulation of T helper cell subsets by cyclooxygenases and their metabolites. Prostaglandins Other Lipid Mediat, 104-105, 74-83. [Abstract Li H, Edin ML, Gruzdev A, Cheng J, Bradbury JA, Graves JP, DeGraff LM and Zeldin DC. (2013) Regulation of T helper cell subsets by cyclooxygenases and their metabolites. Prostaglandins Other Lipid Mediat, 104-105, 74-83.]
  19. Cheng J, Dackor RT, Bradbury JA, Li H, DeGraff LM, Hong LK, King D, Lih FB, Gruzdev A, Edin ML, Travlos GS, Flake GP, Tomer KB and Zeldin DC. (2015) Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis. FASEB J, 30:160-73. [Abstract Cheng J, Dackor RT, Bradbury JA, Li H, DeGraff LM, Hong LK, King D, Lih FB, Gruzdev A, Edin ML, Travlos GS, Flake GP, Tomer KB and Zeldin DC. (2015) Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis. FASEB J, 30:160-73.]
  20. Jerschow E, Edin ML, Chi Y, Hurst B, Abuzeid WM, Akbar NA, Gibber M, Fried MP, Han W, Pelletier T, Ren Z, Keskin T, Roizen G, Lih FB, Gruzdev A, Bradbury JA, Schuster V, Spivack S, Rosenstreich D, and Zeldin DC. (2019) Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease. J Allergy Clin Immunol Pract. 7:1580-8. [Abstract Jerschow E, Edin ML, Chi Y, Hurst B, Abuzeid WM, Akbar NA, Gibber M, Fried MP, Han W, Pelletier T, Ren Z, Keskin T, Roizen G, Lih FB, Gruzdev A, Bradbury JA, Schuster V, Spivack S, Rosenstreich D, and Zeldin DC. (2019) Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease. J Allergy Clin Immunol Pract. 7:1580-8.]

Allergen Exposure and Intervention

  1. Vojta PJ, Randels S, Stout J, Muilenberg M, Burge H, Mitchell H, O'Conner G, Zeldin DC. (2001) Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban homes. Environ Health Perspect. 109:815-9. [Abstract Vojta PJ, Randels S, Stout J, Muilenberg M, Burge H, Mitchell H, O'Conner G, Zeldin DC. (2001) Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban homes. Environ Health Perspect. 109:815-9.]
  2. Jacobs DE, Clickner RP, Zhou JY, Viet SM, Marker DA, Rogers JW, Zeldin DC, Broene P, Friedman W. (2002) The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect. 110:A599-606. [Abstract Jacobs DE, Clickner RP, Zhou JY, Viet SM, Marker DA, Rogers JW, Zeldin DC, Broene P, Friedman W. (2002) The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect. 110:A599-606.] [Full Text Jacobs DE, Clickner RP, Zhou JY, Viet SM, Marker DA, Rogers JW, Zeldin DC, Broene P, Friedman W. (2002) The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect. 110:A599-606.] [PDF Jacobs DE, Clickner RP, Zhou JY, Viet SM, Marker DA, Rogers JW, Zeldin DC, Broene P, Friedman W. (2002) The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect. 110:A599-606.]
  3. Vojta PJ, Friedman W, Marker D, Clickner R, Rogers JW, Viet SM, Muilenberg ML, Burge HA, Thorne PS, Arbes SJ, Zeldin DC. (2002) First National Survey of Lead and Allergens in Housing: survey design and methods for the allergen and endotoxin components. Environ Health Perspect. 110:527-32. [Abstract Vojta PJ, Friedman W, Marker D, Clickner R, Rogers JW, Viet SM, Muilenberg ML, Burge HA, Thorne PS, Arbes SJ, Zeldin DC. (2002) First National Survey of Lead and Allergens in Housing: survey design and methods for the allergen and endotoxin components. Environ Health Perspect. 110:527-32.]
  4. Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2003) House dust mite allergens in U.S. beds: Results from the First National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 111:408-14. [Abstract Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2003) House dust mite allergens in U.S. beds: Results from the First National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 111:408-14.] [Full Text Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2003) House dust mite allergens in U.S. beds: Results from the First National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 111:408-14.]
  5. Chulada PC, Arbes SJ, Dunson D, Zeldin DC. Breast-feeding and the prevalence of asthma and wheeze in children: Analyses from the Third National Health and Nutrition Examination Survey, 1988-1994. J Allergy Clin Immunol. 111:328-36. [Abstract Chulada PC, Arbes SJ, Dunson D, Zeldin DC. Breast-feeding and the prevalence of asthma and wheeze in children: Analyses from the Third National Health and Nutrition Examination Survey, 1988-1994. J Allergy Clin Immunol. 111:328-36.] [Full Text Chulada PC, Arbes SJ, Dunson D, Zeldin DC. Breast-feeding and the prevalence of asthma and wheeze in children: Analyses from the Third National Health and Nutrition Examination Survey, 1988-1994. J Allergy Clin Immunol. 111:328-36.] [PDF Chulada PC, Arbes SJ, Dunson D, Zeldin DC. Breast-feeding and the prevalence of asthma and wheeze in children: Analyses from the Third National Health and Nutrition Examination Survey, 1988-1994. J Allergy Clin Immunol. 111:328-36.]
  6. Arbes SJ, Sever M, Archer J, Long EH, Gore C, Schal C, Walter M, Neubler B, Vaughn B, Mitchell H, Liu E, Collette N, Adler P, Sandel M, Zeldin D.C. (2003) Abatement of cockroach allergen (Bla g 1) in low-income, urban housing: A randomized control trial. J Allergy Clin Immunol. 112:339-45. [Abstract Arbes SJ, Sever M, Archer J, Long EH, Gore C, Schal C, Walter M, Neubler B, Vaughn B, Mitchell H, Liu E, Collette N, Adler P, Sandel M, Zeldin D.C. (2003) Abatement of cockroach allergen (Bla g 1) in low-income, urban housing: A randomized control trial. J Allergy Clin Immunol. 112:339-45.] [Full Text Arbes SJ, Sever M, Archer J, Long EH, Gore C, Schal C, Walter M, Neubler B, Vaughn B, Mitchell H, Liu E, Collette N, Adler P, Sandel M, Zeldin D.C. (2003) Abatement of cockroach allergen (Bla g 1) in low-income, urban housing: A randomized control trial. J Allergy Clin Immunol. 112:339-45.] [PDF Arbes SJ, Sever M, Archer J, Long EH, Gore C, Schal C, Walter M, Neubler B, Vaughn B, Mitchell H, Liu E, Collette N, Adler P, Sandel M, Zeldin D.C. (2003) Abatement of cockroach allergen (Bla g 1) in low-income, urban housing: A randomized control trial. J Allergy Clin Immunol. 112:339-45.]
  7. Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2004) Dog allergen (Can f 1) and cat allergen (Fel d 1) in U.S. homes: Results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 114:111-7. [Abstract Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2004) Dog allergen (Can f 1) and cat allergen (Fel d 1) in U.S. homes: Results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 114:111-7.] [PDF Arbes SJ, Cohn R, Yin M, Muilenberg ML, Burge HA, Friedman W, Zeldin DC. (2004) Dog allergen (Can f 1) and cat allergen (Fel d 1) in U.S. homes: Results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 114:111-7.]
  8. Arbes SJ, Sever M, Mehta J, Gore JC, Schal C, Vaughn B, Mitchell H, Zeldin DC. (2004) Abatement of cockroach allergens (Bla g 1 and Bla g 2) in low-income, urban housing: Month 12 continuation results. J Allergy Clin Immunol. 113:109-14. [Abstract Arbes SJ, Sever M, Mehta J, Gore JC, Schal C, Vaughn B, Mitchell H, Zeldin DC. (2004) Abatement of cockroach allergens (Bla g 1 and Bla g 2) in low-income, urban housing: Month 12 continuation results. J Allergy Clin Immunol. 113:109-14.] [Full Text Arbes SJ, Sever M, Mehta J, Gore JC, Schal C, Vaughn B, Mitchell H, Zeldin DC. (2004) Abatement of cockroach allergens (Bla g 1 and Bla g 2) in low-income, urban housing: Month 12 continuation results. J Allergy Clin Immunol. 113:109-14.] [PDF Arbes SJ, Sever M, Mehta J, Gore JC, Schal C, Vaughn B, Mitchell H, Zeldin DC. (2004) Abatement of cockroach allergens (Bla g 1 and Bla g 2) in low-income, urban housing: Month 12 continuation results. J Allergy Clin Immunol. 113:109-14.]
  9. Cohn RD, Arbes SJ, Jr., Yin M, Jaramillo R and Zeldin DC. (2004) National prevalence and exposure risk for mouse allergen in US households. J Allergy Clin Immunol, 113:1167-71. [Abstract Cohn RD, Arbes SJ, Jr., Yin M, Jaramillo R and Zeldin DC. (2004) National prevalence and exposure risk for mouse allergen in US households. J Allergy Clin Immunol, 113:1167-71.]
  10. Arbes SJ, Jr., Gergen PJ, Elliott L and Zeldin DC. (2005) Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey. J Allergy Clin Immunol, 116:377-83. [Abstract Arbes SJ, Jr., Gergen PJ, Elliott L and Zeldin DC. (2005) Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey. J Allergy Clin Immunol, 116:377-83.]
  11. Arbes SJ, Sever M, Mehta J, Collette N, Thomas B and Zeldin DC. (2005) Exposure to indoor allergens in day-care facilities: results from 2 North Carolina counties. J Allergy Clin Immunol, 116:133-9. [Abstract Arbes SJ, Sever M, Mehta J, Collette N, Thomas B and Zeldin DC. (2005) Exposure to indoor allergens in day-care facilities: results from 2 North Carolina counties. J Allergy Clin Immunol, 116:133-9.] [PDF Arbes SJ, Sever M, Mehta J, Collette N, Thomas B and Zeldin DC. (2005) Exposure to indoor allergens in day-care facilities: results from 2 North Carolina counties. J Allergy Clin Immunol, 116:133-9.]
  12. Arbes SJ, Sever M, Vaughn B, Mehta J, Lynch JT, Mitchell H, Hoppin JA, Spencer HL, Sandler DP, Zeldin DC. (2005) Feasibility of using subject-collected dust samples in epidemiologic and clinical studies of indoor allergens. Environ Health Perspect. 113:665-9. [Abstract Arbes SJ, Sever M, Vaughn B, Mehta J, Lynch JT, Mitchell H, Hoppin JA, Spencer HL, Sandler DP, Zeldin DC. (2005) Feasibility of using subject-collected dust samples in epidemiologic and clinical studies of indoor allergens. Environ Health Perspect. 113:665-9.] [Full Text Arbes SJ, Sever M, Vaughn B, Mehta J, Lynch JT, Mitchell H, Hoppin JA, Spencer HL, Sandler DP, Zeldin DC. (2005) Feasibility of using subject-collected dust samples in epidemiologic and clinical studies of indoor allergens. Environ Health Perspect. 113:665-9.] [PDF Arbes SJ, Sever M, Vaughn B, Mehta J, Lynch JT, Mitchell H, Hoppin JA, Spencer HL, Sandler DP, Zeldin DC. (2005) Feasibility of using subject-collected dust samples in epidemiologic and clinical studies of indoor allergens. Environ Health Perspect. 113:665-9.]
  13. Salo PM, Yin M, Arbes SJ Jr, Cohn RD, Sever M, Muilenberg M, Burge HA, London SJ, Zeldin DC. (2005) Dustborne Alternaria alternata antigens in US homes: results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 116:623-9. [Abstract Salo PM, Yin M, Arbes SJ Jr, Cohn RD, Sever M, Muilenberg M, Burge HA, London SJ, Zeldin DC. (2005) Dustborne Alternaria alternata antigens in US homes: results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 116:623-9.]
  14. Pate A, Hamilton RG, Ashley PJ, Zeldin DC, Halsey JF. (2005) Proficiency testing of allergen measurements in residential dust. J Allergy Clin Immunol. 116:844-50. [Abstract Pate A, Hamilton RG, Ashley PJ, Zeldin DC, Halsey JF. (2005) Proficiency testing of allergen measurements in residential dust. J Allergy Clin Immunol. 116:844-50.] [Full Text Pate A, Hamilton RG, Ashley PJ, Zeldin DC, Halsey JF. (2005) Proficiency testing of allergen measurements in residential dust. J Allergy Clin Immunol. 116:844-50.] [PDF Pate A, Hamilton RG, Ashley PJ, Zeldin DC, Halsey JF. (2005) Proficiency testing of allergen measurements in residential dust. J Allergy Clin Immunol. 116:844-50.]
  15. Thorne PS, Kulhankova K, Yin M, Cohn R, Arbes SJ, Jr. and Zeldin DC. (2005) Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing. Am J Respir Crit Care Med, 172:1371-7. [Abstract Thorne PS, Kulhankova K, Yin M, Cohn R, Arbes SJ, Jr. and Zeldin DC. (2005) Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing. Am J Respir Crit Care Med, 172:1371-7.]
  16. Resnick DB, Sharp R, Zeldin DC. (2005) Research on environmental health interventions: ethical problems and solutions. Account Res. 12:69-101. [Abstract Resnick DB, Sharp R, Zeldin DC. (2005) Research on environmental health interventions: ethical problems and solutions. Account Res. 12:69-101.]
  17. Arbes SJ, Sever ML, Vaughn B, Cohen EA, Zeldin DC. (2006) Oral pathogens and allergic disease: Results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 118:169-75. [Abstract Arbes SJ, Sever ML, Vaughn B, Cohen EA, Zeldin DC. (2006) Oral pathogens and allergic disease: Results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 118:169-75.] [Full Text Arbes SJ, Sever ML, Vaughn B, Cohen EA, Zeldin DC. (2006) Oral pathogens and allergic disease: Results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 118:169-75.] [PDF Arbes SJ, Sever ML, Vaughn B, Cohen EA, Zeldin DC. (2006) Oral pathogens and allergic disease: Results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 118:169-75.]
  18. Barnes C, Portnoy J, Sever M, Arbes SJ, Vaughn B, Zeldin DC. (2006) Comparison of enzyme immunoassay-based assays for environmental alternaria alternata. Ann Allergy Asthma Immunol. 97:350-6. [Abstract Barnes C, Portnoy J, Sever M, Arbes SJ, Vaughn B, Zeldin DC. (2006) Comparison of enzyme immunoassay-based assays for environmental alternaria alternata. Ann Allergy Asthma Immunol. 97:350-6.] [Full Text Barnes C, Portnoy J, Sever M, Arbes SJ, Vaughn B, Zeldin DC. (2006) Comparison of enzyme immunoassay-based assays for environmental alternaria alternata. Ann Allergy Asthma Immunol. 97:350-6.] [PDF Barnes C, Portnoy J, Sever M, Arbes SJ, Vaughn B, Zeldin DC. (2006) Comparison of enzyme immunoassay-based assays for environmental alternaria alternata. Ann Allergy Asthma Immunol. 97:350-6.]
  19. Salo, P.M., Arbes, S.J., Cohn, R.D., Burge, H.A., London, S.J. and Zeldin, D.C. (2006) Alternaria alternata antigens in U.S. homes. J Allergy Clin Immunol. 117:473; author reply 474. [Abstract Salo, P.M., Arbes, S.J., Cohn, R.D., Burge, H.A., London, S.J. and Zeldin, D.C. (2006) Alternaria alternata antigens in U.S. homes. J Allergy Clin Immunol. 117:473; author reply 474.] [Full Text Salo, P.M., Arbes, S.J., Cohn, R.D., Burge, H.A., London, S.J. and Zeldin, D.C. (2006) Alternaria alternata antigens in U.S. homes. J Allergy Clin Immunol. 117:473; author reply 474.] [PDF Salo, P.M., Arbes, S.J., Cohn, R.D., Burge, H.A., London, S.J. and Zeldin, D.C. (2006) Alternaria alternata antigens in U.S. homes. J Allergy Clin Immunol. 117:473; author reply 474.]
  20. Salo PM, Arbes SJ, Sever M, Jaramillo R, Cohn RD, London SJ, Zeldin DC. (2006) Exposure to alternaria alternata in us homes is associated with asthma symptoms. J Allergy Clin Immunol. 118:892-8. [Abstract Salo PM, Arbes SJ, Sever M, Jaramillo R, Cohn RD, London SJ, Zeldin DC. (2006) Exposure to alternaria alternata in us homes is associated with asthma symptoms. J Allergy Clin Immunol. 118:892-8.] [Full Text Salo PM, Arbes SJ, Sever M, Jaramillo R, Cohn RD, London SJ, Zeldin DC. (2006) Exposure to alternaria alternata in us homes is associated with asthma symptoms. J Allergy Clin Immunol. 118:892-8.] [PDF Salo PM, Arbes SJ, Sever M, Jaramillo R, Cohn RD, London SJ, Zeldin DC. (2006) Exposure to alternaria alternata in us homes is associated with asthma symptoms. J Allergy Clin Immunol. 118:892-8.]
  21. Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D. (2006) How exposures to biologics influence the induction and incidence of asthma. Environ Health Perspect. 114:620-6. [Abstract Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D. (2006) How exposures to biologics influence the induction and incidence of asthma. Environ Health Perspect. 114:620-6.] [Full Text Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D. (2006) How exposures to biologics influence the induction and incidence of asthma. Environ Health Perspect. 114:620-6.] [PDF Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D. (2006) How exposures to biologics influence the induction and incidence of asthma. Environ Health Perspect. 114:620-6.]
  22. Arbes SJ, Gergen PJ, Vaughn B, Zeldin DC. (2007) Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol.120:1139-45. 2007. [Abstract Arbes SJ, Gergen PJ, Vaughn B, Zeldin DC. (2007) Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol.120:1139-45. 2007.] [Full Text Arbes SJ, Gergen PJ, Vaughn B, Zeldin DC. (2007) Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol.120:1139-45. 2007.] [PDF Arbes SJ, Gergen PJ, Vaughn B, Zeldin DC. (2007) Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol.120:1139-45. 2007.]
  23. Elliott L, Arbes SJ, Harvey ES, Lee RC, Salo PM, Cohn RD, London SJ, Zeldin DC. (2007) Dust weight and asthma prevalence in the National Survey of Lead and Allergens in Housing (NSLAH). Environ Health Perspect. 115:215-20. [Abstract Elliott L, Arbes SJ, Harvey ES, Lee RC, Salo PM, Cohn RD, London SJ, Zeldin DC. (2007) Dust weight and asthma prevalence in the National Survey of Lead and Allergens in Housing (NSLAH). Environ Health Perspect. 115:215-20.] [Full Text Elliott L, Arbes SJ, Harvey ES, Lee RC, Salo PM, Cohn RD, London SJ, Zeldin DC. (2007) Dust weight and asthma prevalence in the National Survey of Lead and Allergens in Housing (NSLAH). Environ Health Perspect. 115:215-20.] [PDF Elliott L, Arbes SJ, Harvey ES, Lee RC, Salo PM, Cohn RD, London SJ, Zeldin DC. (2007) Dust weight and asthma prevalence in the National Survey of Lead and Allergens in Housing (NSLAH). Environ Health Perspect. 115:215-20.]
  24. Sever ML, Arbes SJ, Jr., Gore JC, Santangelo RG, Vaughn B, Mitchell H, Schal C and Zeldin DC. (2007) Cockroach allergen reduction by cockroach control alone in low-income urban homes: a randomized control trial. J Allergy Clin Immunol, 120:849-55. [Abstract Sever ML, Arbes SJ, Jr., Gore JC, Santangelo RG, Vaughn B, Mitchell H, Schal C and Zeldin DC. (2007) Cockroach allergen reduction by cockroach control alone in low-income urban homes: a randomized control trial. J Allergy Clin Immunol, 120:849-55.]
  25. Resnik D, Zeldin D. (2008) Environmental health research on hazards in the home and the duty to warn. Bioethics 22:209-217. [Abstract Resnik D, Zeldin D. (2008) Environmental health research on hazards in the home and the duty to warn. Bioethics 22:209-217.] [Full Text Resnik D, Zeldin D. (2008) Environmental health research on hazards in the home and the duty to warn. Bioethics 22:209-217.] [PDF Resnik D, Zeldin D. (2008) Environmental health research on hazards in the home and the duty to warn. Bioethics 22:209-217.]
  26. Salo PM, Arbes SJ, Jr., Crockett PW, Thorne PS, Cohn RD and Zeldin DC. (2008) Exposure to multiple indoor allergens in US homes and its relationship to asthma. J Allergy Clin Immunol, 121:678-684 e2. [Abstract Salo PM, Arbes SJ, Jr., Crockett PW, Thorne PS, Cohn RD and Zeldin DC. (2008) Exposure to multiple indoor allergens in US homes and its relationship to asthma. J Allergy Clin Immunol, 121:678-684 e2.]
  27. Fessler MB, Massing MW, Spruell B, Jaramillo R, Draper DW, Madenspacher JH, Arbes SJ, Calatroni A, Zeldin DC. (2009) Novel relationship of serum cholesterol with asthma and wheeze in the United States. J Allergy Clin Immunol. 124:967-74.e1-15. [Abstract Fessler MB, Massing MW, Spruell B, Jaramillo R, Draper DW, Madenspacher JH, Arbes SJ, Calatroni A, Zeldin DC. (2009) Novel relationship of serum cholesterol with asthma and wheeze in the United States. J Allergy Clin Immunol. 124:967-74.e1-15.]
  28. Gergen PJ, Arbes SJ, Calatroni A, Mitchell HE, Zeldin DC. (2009) Total IgE and asthma prevalence in the U.S. population: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 124:447-53. [Abstract Gergen PJ, Arbes SJ, Calatroni A, Mitchell HE, Zeldin DC. (2009) Total IgE and asthma prevalence in the U.S. population: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 124:447-53.] [Full Text Gergen PJ, Arbes SJ, Calatroni A, Mitchell HE, Zeldin DC. (2009) Total IgE and asthma prevalence in the U.S. population: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 124:447-53.] [PDF Gergen PJ, Arbes SJ, Calatroni A, Mitchell HE, Zeldin DC. (2009) Total IgE and asthma prevalence in the U.S. population: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 124:447-53.]
  29. Salo PM, Jaramillo R, Cohn RD, London SJ and Zeldin DC. (2009) Exposure to mouse allergen in U.S. homes associated with asthma symptoms. Environ Health Perspect, 117:387-91. [Abstract Salo PM, Jaramillo R, Cohn RD, London SJ and Zeldin DC. (2009) Exposure to mouse allergen in U.S. homes associated with asthma symptoms. Environ Health Perspect, 117:387-91.]
  30. Salo PM, Sever ML and Zeldin DC. (2009) Indoor allergens in school and day care environments. J Allergy Clin Immunol, 124:185-92, 192 e1-9; quiz 193-4. [Abstract Salo PM, Sever ML and Zeldin DC. (2009) Indoor allergens in school and day care environments. J Allergy Clin Immunol, 124:185-92, 192 e1-9; quiz 193-4.]
  31. Salo PM, Zeldin DC. Does exposure to cats and dogs decrease the risk of developing allergic sensitization and disease? J Allergy Clin Immunol, 124:751-2. [Abstract Salo PM, Zeldin DC. Does exposure to cats and dogs decrease the risk of developing allergic sensitization and disease? J Allergy Clin Immunol, 124:751-2.] [Full Text Salo PM, Zeldin DC. Does exposure to cats and dogs decrease the risk of developing allergic sensitization and disease? J Allergy Clin Immunol, 124:751-2.] [PDF Salo PM, Zeldin DC. Does exposure to cats and dogs decrease the risk of developing allergic sensitization and disease? J Allergy Clin Immunol, 124:751-2.]
  32. Thorne PS, Cohn RD, Mav D, Arbes SJ and Zeldin DC. (2009) Predictors of endotoxin levels in U.S. housing. Environ Health Perspect, 117:763-71. [Abstract Thorne PS, Cohn RD, Mav D, Arbes SJ and Zeldin DC. (2009) Predictors of endotoxin levels in U.S. housing. Environ Health Perspect, 117:763-71.]
  33. Visness CM, London SJ, Daniels JL, Kaufman JS, Yeatts KB, Siega-Riz AM, Liu AH, Calatroni A and Zeldin DC. (2009) Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol, 123:1163-9, 1169 e1-4. [Abstract Visness CM, London SJ, Daniels JL, Kaufman JS, Yeatts KB, Siega-Riz AM, Liu AH, Calatroni A and Zeldin DC. (2009) Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol, 123:1163-9, 1169 e1-4.]
  34. Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of serum cholesterol levels to atopy in the U.S. population. Allergy. 65:859-64. [Abstract Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of serum cholesterol levels to atopy in the U.S. population. Allergy. 65:859-64.] [Full Text Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of serum cholesterol levels to atopy in the U.S. population. Allergy. 65:859-64.] [PDF Fessler MB, Jaramillo R, Crockett PW, Zeldin DC. (2010) Relationship of serum cholesterol levels to atopy in the U.S. population. Allergy. 65:859-64.]
  35. Krieger J, Jacobs DE, Ashley PJ, Bzaeder A, Chew GL, Dearborn D, Hynes HP, Miller JD, Morley R, Rabito F, Zeldin DC. (2010) Housing interventions and control of asthma-related indoor biologic agents: A review of the evidence. J Public Health Manag Pract. 16:S11-20. [Abstract Krieger J, Jacobs DE, Ashley PJ, Bzaeder A, Chew GL, Dearborn D, Hynes HP, Miller JD, Morley R, Rabito F, Zeldin DC. (2010) Housing interventions and control of asthma-related indoor biologic agents: A review of the evidence. J Public Health Manag Pract. 16:S11-20.] [Full Text Krieger J, Jacobs DE, Ashley PJ, Bzaeder A, Chew GL, Dearborn D, Hynes HP, Miller JD, Morley R, Rabito F, Zeldin DC. (2010) Housing interventions and control of asthma-related indoor biologic agents: A review of the evidence. J Public Health Manag Pract. 16:S11-20.] [PDF Krieger J, Jacobs DE, Ashley PJ, Bzaeder A, Chew GL, Dearborn D, Hynes HP, Miller JD, Morley R, Rabito F, Zeldin DC. (2010) Housing interventions and control of asthma-related indoor biologic agents: A review of the evidence. J Public Health Manag Pract. 16:S11-20.]
  36. Liu AH, Jaramillo R., Sicherer SH, Wood RA, Bock SA, Burks AW, Massing M, Cohn RD, Zeldin DC.(2010) National Prevalence and Risk Factors for Food Allergy and Relationship to Asthma: Results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol. 126:798-806. [Abstract Liu AH, Jaramillo R., Sicherer SH, Wood RA, Bock SA, Burks AW, Massing M, Cohn RD, Zeldin DC.(2010) National Prevalence and Risk Factors for Food Allergy and Relationship to Asthma: Results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol. 126:798-806.]
  37. Salo PM and Zeldin DC. (2010) Cats and dogs: an attractive remedy versus atopy? J Allergy Clin Immunol, 125:765-6. [Abstract Salo PM and Zeldin DC. (2010) Cats and dogs: an attractive remedy versus atopy? J Allergy Clin Immunol, 125:765-6.]
  38. Visness CM, London SJ, Daniels JL, Kaufman JS, Yeatts KB, Siega-Riz AM, Calatroni A, Zeldin DC. (2010) Association of Childhood Obesity with Atopic and Non-Atopic Asthma: Results from the National Health and Nutrition Examination Survey 1999-2006. J Asthma. 2010 47:822-829. [Abstract Visness CM, London SJ, Daniels JL, Kaufman JS, Yeatts KB, Siega-Riz AM, Calatroni A, Zeldin DC. (2010) Association of Childhood Obesity with Atopic and Non-Atopic Asthma: Results from the National Health and Nutrition Examination Survey 1999-2006. J Asthma. 2010 47:822-829.]
  39. Hoppin JA, Jaramillo R, Salo P, Sandler DP, London SJ, Zeldin DC. (2011) Questionnaire predictors of atopy in a U.S. population sample: Findings from the National Health and Nutrition Examination Survey, 2005-2006. Am J Epidemiol. 173:544-552. [Abstract Hoppin JA, Jaramillo R, Salo P, Sandler DP, London SJ, Zeldin DC. (2011) Questionnaire predictors of atopy in a U.S. population sample: Findings from the National Health and Nutrition Examination Survey, 2005-2006. Am J Epidemiol. 173:544-552.]
  40. Salo PM, Calatroni A, Gergen PJ, Hoppin JA, Sever ML, Jaramillo R, Arbes SJ, Zeldin DC. (2011) Allergy-related outcomes in relation to serum IgE: Results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol. 127:1226-1235.e7. [Abstract Salo PM, Calatroni A, Gergen PJ, Hoppin JA, Sever ML, Jaramillo R, Arbes SJ, Zeldin DC. (2011) Allergy-related outcomes in relation to serum IgE: Results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol. 127:1226-1235.e7.]
  41. Sever ML, Salo PM, Haynes AK, Zeldin DC. (2011) Inner-city environments and mitigation of cockroach allergen. Am J Prev Med. 41:S55-56. [Abstract Sever ML, Salo PM, Haynes AK, Zeldin DC. (2011) Inner-city environments and mitigation of cockroach allergen. Am J Prev Med. 41:S55-56.] [Full Text Sever ML, Salo PM, Haynes AK, Zeldin DC. (2011) Inner-city environments and mitigation of cockroach allergen. Am J Prev Med. 41:S55-56.]
  42. Busse PJ, Cohn RD, Salo PM and Zeldin DC. (2013) Characteristics of allergic sensitization among asthmatic adults older than 55 years: results from the National Health and Nutrition Examination Survey, 2005-2006. Ann Allergy Asthma Immunol, 110:247-52. [Abstract Busse PJ, Cohn RD, Salo PM and Zeldin DC. (2013) Characteristics of allergic sensitization among asthmatic adults older than 55 years: results from the National Health and Nutrition Examination Survey, 2005-2006. Ann Allergy Asthma Immunol, 110:247-52.]
  43. Hoppin JA, Jaramillo R, London SJ, Bertelsen RJ, Salo PM, Sandler DP and Zeldin DC. (2013) Phthalate exposure and allergy in the U.S. population: results from NHANES 2005-2006. Environ Health Perspect, 121:1129-34. [Abstract Hoppin JA, Jaramillo R, London SJ, Bertelsen RJ, Salo PM, Sandler DP and Zeldin DC. (2013) Phthalate exposure and allergy in the U.S. population: results from NHANES 2005-2006. Environ Health Perspect, 121:1129-34.]
  44. Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. (2013) Relation between objective measures of atopy and myocardial infarction in the United States. J Allergy and Clin Immunol, 131:405-411. [Abstract Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB. (2013) Relation between objective measures of atopy and myocardial infarction in the United States. J Allergy and Clin Immunol, 131:405-411.]
  45. Weir CH, Yeatts KB, Sarnat JA, Vizuete W, Salo PM, Jaramillo R, Cohn RD, Chu H, Zeldin DC, London SJ. (2013) Nitrogen dioxide and allergic sensitization in the 2005-2006 National Health and Nutrition Examination Survey. Respir Med. 107:1763-72. [Abstract Weir CH, Yeatts KB, Sarnat JA, Vizuete W, Salo PM, Jaramillo R, Cohn RD, Chu H, Zeldin DC, London SJ. (2013) Nitrogen dioxide and allergic sensitization in the 2005-2006 National Health and Nutrition Examination Survey. Respir Med. 107:1763-72.]
  46. Hoppin JA, Umbach DM, Long S, Rinsky JL, Henneberger PK, Salo PM, Zeldin DC, London SJ, Alavanja MC, Blair A, Beane Freeman LE, Sandler DP. (2014) Respiratory disease in United States farmers. Occup Environ Med, 71:484-491. [Abstract Hoppin JA, Umbach DM, Long S, Rinsky JL, Henneberger PK, Salo PM, Zeldin DC, London SJ, Alavanja MC, Blair A, Beane Freeman LE, Sandler DP. (2014) Respiratory disease in United States farmers. Occup Environ Med, 71:484-491.]
  47. Salo PM, Arbes SJ, Jr., Jaramillo R, Calatroni A, Weir CH, Sever ML, Hoppin JA, Rose KM, Liu AH, Gergen PJ, Mitchell HE and Zeldin DC. (2014) Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 134:350-9. [Abstract Salo PM, Arbes SJ, Jr., Jaramillo R, Calatroni A, Weir CH, Sever ML, Hoppin JA, Rose KM, Liu AH, Gergen PJ, Mitchell HE and Zeldin DC. (2014) Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol, 134:350-9.]
  48. Hernandez-Cadena L, Zeldin DC, Barraza-Villarreal A, Sever ML, Sly PD, London SJ, Escamilla-Nunez MC and Romieu I. (2015) Indoor determinants of dustborne allergens in Mexican homes. Allergy Asthma Proc, 36:130-7. [Abstract Hernandez-Cadena L, Zeldin DC, Barraza-Villarreal A, Sever ML, Sly PD, London SJ, Escamilla-Nunez MC and Romieu I. (2015) Indoor determinants of dustborne allergens in Mexican homes. Allergy Asthma Proc, 36:130-7.]
  49. Thorne PS, Mendy A, Metwali N, Salo P, Co C, Jaramillo R, Rose KM and Zeldin DC. (2015) Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S. Am J Respir Crit Care Med. 192:1287-97. [Abstract Thorne PS, Mendy A, Metwali N, Salo P, Co C, Jaramillo R, Rose KM and Zeldin DC. (2015) Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S. Am J Respir Crit Care Med. 192:1287-97.]
  50. Winn AK, Salo PM, Klein C, Sever ML, Zombeck A, Harris SF , Johndrow D , Crockett PW, Cohn RD , ZeldinDC. (2016) Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study. The J Asthma, 53:133-138. [Abstract Winn AK, Salo PM, Klein C, Sever ML, Zombeck A, Harris SF , Johndrow D , Crockett PW, Cohn RD , ZeldinDC. (2016) Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study. The J Asthma, 53:133-138.]
  51. McGowan EC, Matsui EC, Peng R, Salo PM, Zeldin DC and Keet CA. (2016) Racial/ethnic and socioeconomic differences in self-reported food allergy among food-sensitized children in National Health and Nutrition Examination Survey III. Ann Allergy Asthma Immunol, 117:570-572 e3. [Abstract McGowan EC, Matsui EC, Peng R, Salo PM, Zeldin DC and Keet CA. (2016) Racial/ethnic and socioeconomic differences in self-reported food allergy among food-sensitized children in National Health and Nutrition Examination Survey III. Ann Allergy Asthma Immunol, 117:570-572 e3.]
  52. McGowan EC, Peng RD, Salo PM, Zeldin DC and Keet CA. (2016) Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES). J Allergy Clin Immunol Pract, 4:713-20. [Abstract McGowan EC, Peng RD, Salo PM, Zeldin DC and Keet CA. (2016) Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES). J Allergy Clin Immunol Pract, 4:713-20.]
  53. Gold DR, Adamkiewicz G, Arshad SH, Celedon JC, Chapman MD, Chew GL, Cook DN, Custovic A, Gehring U, Gern JE, Johnson CC, Kennedy S, Koutrakis P, Leaderer B, Mitchell H, Litonjua AA, Mueller GA, O'Connor GT, Ownby D, Phipatanakul W, Persky V, Perzanowski MS, Ramsey CD, Salo PM, Schwaninger JM, Sordillo JE, Spira A, Suglia SF, Togias A, Zeldin DC and Matsui EC. (2017) NIAID, NIEHS, NHLBI, MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management. J Allergy Clin Immunol. 140:933-49. [Abstract Gold DR, Adamkiewicz G, Arshad SH, Celedon JC, Chapman MD, Chew GL, Cook DN, Custovic A, Gehring U, Gern JE, Johnson CC, Kennedy S, Koutrakis P, Leaderer B, Mitchell H, Litonjua AA, Mueller GA, O'Connor GT, Ownby D, Phipatanakul W, Persky V, Perzanowski MS, Ramsey CD, Salo PM, Schwaninger JM, Sordillo JE, Spira A, Suglia SF, Togias A, Zeldin DC and Matsui EC. (2017) NIAID, NIEHS, NHLBI, MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management. J Allergy Clin Immunol. 140:933-49.]
  54. Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, and Zeldin DC. (2017) House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies. Environ Health Perspect, 125:057010. [Abstract Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, and Zeldin DC. (2017) House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies. Environ Health Perspect, 125:057010.]
  55. Salo PM, Zeldin DC. (2018) Mite-impermeable bedding casings and severe asthma exacerbations. The Journal of Pediatrics, 192:266-269. [Abstract Salo PM, Zeldin DC. (2018) Mite-impermeable bedding casings and severe asthma exacerbations. The Journal of Pediatrics, 192:266-269.]
  56. Salo PM, Wilkerson J, Rose KM, Cohn RD, Calatroni A, Mitchell HE, Sever ML, Gergen PJ, Thorne PS, and Zeldin DC. (2018) Bedroom allergen exposures in US households. J Allergy Clin Immunol, 141:1870-9 e14. [Abstract Salo PM, Wilkerson J, Rose KM, Cohn RD, Calatroni A, Mitchell HE, Sever ML, Gergen PJ, Thorne PS, and Zeldin DC. (2018) Bedroom allergen exposures in US households. J Allergy Clin Immunol, 141:1870-9 e14.]
  57. Salo PM, Cohn RD, and Zeldin DC. (2018) Bedroom Allergen Exposure Beyond House Dust Mites. Curr Allergy Asthma Rep, 18:52. [Abstract Salo PM, Cohn RD, and Zeldin DC. (2018) Bedroom Allergen Exposure Beyond House Dust Mites. Curr Allergy Asthma Rep, 18:52.]
  58. Mendy A, Wilkerson J, Salo PM, Cohn RD, Zeldin DC, and Thorne PS. (2018) Exposure and Sensitization to Pets Modify Endotoxin Association with Asthma and Wheeze. J Allergy Clin Immunol Pract, 6:2006-13 e4. [Abstract Mendy A, Wilkerson J, Salo PM, Cohn RD, Zeldin DC, and Thorne PS. (2018) Exposure and Sensitization to Pets Modify Endotoxin Association with Asthma and Wheeze. J Allergy Clin Immunol Pract, 6:2006-13 e4.]
  59. Mendy A, Wilkerson J, Salo PM, Cohn RD, Zeldin DC, and Thorne PS. (2018) Endotoxin predictors and associated respiratory outcomes differ with climate regions in the U.S. Environ Int, 112:218-26. [Abstract Mendy A, Wilkerson J, Salo PM, Cohn RD, Zeldin DC, and Thorne PS. (2018) Endotoxin predictors and associated respiratory outcomes differ with climate regions in the U.S. Environ Int, 112:218-26.]
  60. Mendy A, Salo PM, Cohn RD, Wilkerson J, Zeldin DC, and Thorne PS. (2018) House Dust Endotoxin Association with Chronic Bronchitis and Emphysema. Environ Health Perspect, 126:037007. [Abstract Mendy A, Salo PM, Cohn RD, Wilkerson J, Zeldin DC, and Thorne PS. (2018) House Dust Endotoxin Association with Chronic Bronchitis and Emphysema. Environ Health Perspect, 126:037007.]
  61. Cloutier MM, Salo PM, Akinbami LJ, Cohn RD, Wilkerson JC, Diette GB, Williams S, Elward KS, Mazurek JM, Spinner JR, Mitchell TA, and Zeldin DC. (2018) Clinician Agreement, Self-Efficacy, and Adherence with the Guidelines for the Diagnosis and Management of Asthma. J Allergy Clin Immunol Pract, 6:886-94 e4. [Abstract Cloutier MM, Salo PM, Akinbami LJ, Cohn RD, Wilkerson JC, Diette GB, Williams S, Elward KS, Mazurek JM, Spinner JR, Mitchell TA, and Zeldin DC. (2018) Clinician Agreement, Self-Efficacy, and Adherence with the Guidelines for the Diagnosis and Management of Asthma. J Allergy Clin Immunol Pract, 6:886-94 e4.]
  62. McGowan EC, Peng R, Salo PM, Zeldin DC, and Keet CA. (2019) Cockroach, dust mite, and shrimp sensitization correlations in the National Health and Nutrition Examination Survey. Ann Allergy Asthma Immunol, 122:536-8 e1. [Abstract McGowan EC, Peng R, Salo PM, Zeldin DC, and Keet CA. (2019) Cockroach, dust mite, and shrimp sensitization correlations in the National Health and Nutrition Examination Survey. Ann Allergy Asthma Immunol, 122:536-8 e1.]
  63. Akinbami LJ, Salo PM, Cloutier MM, Wilkerson JC, Elward KS, Mazurek JM, Williams S, and Zeldin DC. (2019) Primary care clinician adherence with asthma guidelines: the National Asthma Survey of Physicians. J Asthma, 2019:1-13. [Abstract Akinbami LJ, Salo PM, Cloutier MM, Wilkerson JC, Elward KS, Mazurek JM, Williams S, and Zeldin DC. (2019) Primary care clinician adherence with asthma guidelines: the National Asthma Survey of Physicians. J Asthma, 2019:1-13.]
  64. Feinstein L, Wilkerson J, Salo PM, Bridge MF, Fessler MB, Thorne PS, Mendy A, Cohn RD, Curry MD, Zeldin DC. 2020. Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Disease. Epidemiology; doi: 10.1097/EDE.0000000000001176 [Online 4 February 2020]. [Abstract Feinstein L, Wilkerson J, Salo PM, Bridge MF, Fessler MB, Thorne PS, Mendy A, Cohn RD, Curry MD, Zeldin DC. 2020. Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Disease. Epidemiology; doi: 10.1097/EDE.0000000000001176 [Online 4 February 2020].] 

Other Studies

  1. Zeldin DC, Corcia A and Armstrong WM. (1985) Cyclic AMP-induced changes in membrane conductance of Necturus gallbladder epithelial cells. J Membr Biol, 84, 193-206. [Abstract Zeldin DC, Corcia A and Armstrong WM. (1985) Cyclic AMP-induced changes in membrane conductance of Necturus gallbladder epithelial cells. J Membr Biol, 84, 193-206.]
  2. Zhao C, Wang P, Xiao X, Chao J, Chao L, Wang DW and Zeldin DC. (2003) Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats. Hypertension, 42, 1026-33. [Abstract Zhao C, Wang P, Xiao X, Chao J, Chao L, Wang DW and Zeldin DC. (2003) Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats. Hypertension, 42, 1026-33.]
  3. Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL and Zeldin DC. (2003) Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development, 130, 4539-52. [Abstract Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL and Zeldin DC. (2003) Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development, 130, 4539-52.]
  4. Lee CR, North KE, Bray MS, Avery CL, Mosher MJ, Couper DJ, Coresh J, Folsom AR, Boerwinkle E, Heiss G, Zeldin DC. NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: The Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 2006 Dec;16(12):891-899. [Abstract Lee CR, North KE, Bray MS, Avery CL, Mosher MJ, Couper DJ, Coresh J, Folsom AR, Boerwinkle E, Heiss G, Zeldin DC. NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: The Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 2006 Dec;16(12):891-899.] [Full Text Lee CR, North KE, Bray MS, Avery CL, Mosher MJ, Couper DJ, Coresh J, Folsom AR, Boerwinkle E, Heiss G, Zeldin DC. NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: The Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomics. 2006 Dec;16(12):891-899.]
  5. Zhang D, Stumpo DJ, Graves JP, DeGraff LM, Grissom SF, Collins JB, Li L, Zeldin DC and Blackshear PJ. (2006) Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development. J Neurochem, 98, 860-75. [Abstract Zhang D, Stumpo DJ, Graves JP, DeGraff LM, Grissom SF, Collins JB, Li L, Zeldin DC and Blackshear PJ. (2006) Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development. J Neurochem, 98, 860-75.]
  6. Card JW, Voltz JW, Ferguson CD, Carey MA, DeGraff LM, Peddada SD, Morgan DL and Zeldin DC. (2007) Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation. Am J Physiol Lung Cell Mol Physiol, 292, L908-14. [Abstract Card JW, Voltz JW, Ferguson CD, Carey MA, DeGraff LM, Peddada SD, Morgan DL and Zeldin DC. (2007) Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation. Am J Physiol Lung Cell Mol Physiol, 292, L908-14.]
  7. Carey MA, Card JW, Bradbury JA, Moorman MP, Haykal-Coates N, Gavett SH, Graves JP, Walker VR, Flake GP, Voltz JW, Zhu D, Jacobs ER, Dakhama A, Larsen GL, Loader JE, Gelfand EW, Germolec DR, Korach KS and Zeldin DC. (2007) Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice. Am J Respir Crit Care Med, 175, 126-35. [Abstract Carey MA, Card JW, Bradbury JA, Moorman MP, Haykal-Coates N, Gavett SH, Graves JP, Walker VR, Flake GP, Voltz JW, Zhu D, Jacobs ER, Dakhama A, Larsen GL, Loader JE, Gelfand EW, Germolec DR, Korach KS and Zeldin DC. (2007) Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice. Am J Respir Crit Care Med, 175, 126-35.]
  8. Carey MA, Card JW, Voltz JW, Arbes SJ, Jr., Germolec DR, Korach KS and Zeldin DC. (2007) It's all about sex: gender, lung development and lung disease. Trends Endocrinol Metab, 18, 308-13. [Abstract Carey MA, Card JW, Voltz JW, Arbes SJ, Jr., Germolec DR, Korach KS and Zeldin DC. (2007) It's all about sex: gender, lung development and lung disease. Trends Endocrinol Metab, 18, 308-13.]
  9. Carey MA, Card JW, Voltz JW, Germolec DR, Korach KS, Zeldin DC. The impact of sex and sex hormones on lung physiology and disease: Lessons from animal studies. Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L272-8. [Abstract Carey MA, Card JW, Voltz JW, Germolec DR, Korach KS, Zeldin DC. The impact of sex and sex hormones on lung physiology and disease: Lessons from animal studies. Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L272-8.] [Full Text Carey MA, Card JW, Voltz JW, Germolec DR, Korach KS, Zeldin DC. The impact of sex and sex hormones on lung physiology and disease: Lessons from animal studies. Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L272-8.]
  10. Zhang D, Zeldin DC, Blackshear PJ. Regulatory factor X4 variant 3: A transcription factor involved in brain development and disease. J Neurosci Res. 2007 Dec;85(16): 3515-22. [Abstract Zhang D, Zeldin DC, Blackshear PJ. Regulatory factor X4 variant 3: A transcription factor involved in brain development and disease. J Neurosci Res. 2007 Dec;85(16): 3515-22.] [Full Text Zhang D, Zeldin DC, Blackshear PJ. Regulatory factor X4 variant 3: A transcription factor involved in brain development and disease. J Neurosci Res. 2007 Dec;85(16): 3515-22.] [PDF Zhang D, Zeldin DC, Blackshear PJ. Regulatory factor X4 variant 3: A transcription factor involved in brain development and disease. J Neurosci Res. 2007 Dec;85(16): 3515-22.]
  11. Voltz JW, Card JW, Carey MA, DeGraff LM, Ferguson CD, Flake GP, Bonner JC, Korach KS, Zeldin DC. Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2008 Jul;39(1):45-52. [Abstract Voltz JW, Card JW, Carey MA, DeGraff LM, Ferguson CD, Flake GP, Bonner JC, Korach KS, Zeldin DC. Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2008 Jul;39(1):45-52.] [Full Text Voltz JW, Card JW, Carey MA, DeGraff LM, Ferguson CD, Flake GP, Bonner JC, Korach KS, Zeldin DC. Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2008 Jul;39(1):45-52.] [PDF Voltz JW, Card JW, Carey MA, DeGraff LM, Ferguson CD, Flake GP, Bonner JC, Korach KS, Zeldin DC. Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2008 Jul;39(1):45-52.]
  12. Zhang D, Harry JG, Blackshear PJ, Zeldin DC. G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. Journal Biol Chem. 2008 Mar 28;283(13):8580-90. [Abstract Zhang D, Harry JG, Blackshear PJ, Zeldin DC. G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. Journal Biol Chem. 2008 Mar 28;283(13):8580-90.] [Full Text Zhang D, Harry JG, Blackshear PJ, Zeldin DC. G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. Journal Biol Chem. 2008 Mar 28;283(13):8580-90.]
  13. Bonner JC, Card JW, Zeldin DC. Nanoparticle-mediated drug delivery and pulmonary hypertension. Hypertension. 2009 May;53(5):751-3. [Abstract Bonner JC, Card JW, Zeldin DC. Nanoparticle-mediated drug delivery and pulmonary hypertension. Hypertension. 2009 May;53(5):751-3.] [Full Text Bonner JC, Card JW, Zeldin DC. Nanoparticle-mediated drug delivery and pulmonary hypertension. Hypertension. 2009 May;53(5):751-3.] [PDF Bonner JC, Card JW, Zeldin DC. Nanoparticle-mediated drug delivery and pulmonary hypertension. Hypertension. 2009 May;53(5):751-3.]
  14. Card JW, Zeldin DC. (2009) Hormonal influences on lung function and response to environmental agents: Lessons from animal models of respiratory disease. Proc Am Thorac Soc, 6:588-95. [Abstract Card JW, Zeldin DC. (2009) Hormonal influences on lung function and response to environmental agents: Lessons from animal models of respiratory disease. Proc Am Thorac Soc, 6:588-95.]
  15. Chulada PC, Vainorius E, Garantziotis S, Burch L, Blackshear PJ, Zeldin DC. (2011) The Environmental Polymorphism Registry – a unique resource that facilitates translational research of environmental disease. Environmental Health Perspectives, :1523-1527. [Abstract Chulada PC, Vainorius E, Garantziotis S, Burch L, Blackshear PJ, Zeldin DC. (2011) The Environmental Polymorphism Registry – a unique resource that facilitates translational research of environmental disease. Environmental Health Perspectives, :1523-1527.]
  16. Thomas AC, Nouls JC, Driehuys B, Voltz JW, Fubara B, Foley J, Bradbury JA and Zeldin DC. (2011) Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury. Am J Respir Cell Mol Biol, 44: 648-54. [Abstract Thomas AC, Nouls JC, Driehuys B, Voltz JW, Fubara B, Foley J, Bradbury JA and Zeldin DC. (2011) Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury. Am J Respir Cell Mol Biol, 44: 648-54.]
  17. Fessler MB, Rose K, Zhang Y, Jaramillo R and Zeldin DC. (2013) Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population. J Lipid Res, 54, 3177-88. [Abstract Fessler MB, Rose K, Zhang Y, Jaramillo R and Zeldin DC. (2013) Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population. J Lipid Res, 54, 3177-88.]
  18. House JS, Nichols CE, Li H, Brandenberger C, Virgincar RS, DeGraff LM, Driehuys B, Zeldin DC and London SJ. (2017) Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice. Am J Physiol Lung Cell Mol Physiol, 312, L520-L530. [Abstract House JS, Nichols CE, Li H, Brandenberger C, Virgincar RS, DeGraff LM, Driehuys B, Zeldin DC and London SJ. (2017) Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice. Am J Physiol Lung Cell Mol Physiol, 312, L520-L530.]
  19. Edin ML, and Zeldin DC. (2019) An improved protocol for the treatment of fulminant myocarditis. Sci China Life Sci, 62:433-434. [Abstract Edin ML, and Zeldin DC. (2019) An improved protocol for the treatment of fulminant myocarditis. Sci China Life Sci, 62:433-434.]
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