NIEHS Home page Health & Education Research At NIEHS Grant Funded About the Extramural Research and Training Division Centers, Interagency Collaborations, and Consortia Centers of Excellence on Environmental Health Disparities Research Collaborative Centers in Children’s Environmental Health Research and Translation Countermeasures Against Chemical Threats (CounterACT) Program Environmental Health Sciences Core Centers Expanding Genome Integrity Assays to Population Studies Oceans and Human Health Superfund Research Program Events About SRP Community Engagement and Research Translation Data Management and Sharing Materials for Grant Recipients Public Health Impacts Publications Research Briefs Science Digest SRP Funding Opportunities SRP Search Tools Training K.C. Donnelly Externship Award Supplement Karen Wetterhahn Memorial Award 2022 - Amanda Armijo, MIT 2023 – Rollie Mills, University of Kentucky 2021 – Molly Frazar, University of Kentucky 2020 – Jennifer Kay, Massachusetts Institute of Technology 2019 - Elana Elkin, University of Michigan 2018 - Stephanie Kim, Boston University 2017 - Angela Gutierrez, University of Kentucky 2016 - Elizabeth Martin, University of North Carolina at Chapel Hill 2015 – Nishad Jayasundara, Duke University 2014 – Bradley Newsome, University of Kentucky 2013 – Corin Hammond, University of Arizona 2012 – Nicki Baker, University of Kentucky 2011 - Monica Ramirez-Andreotta, University of Arizona 2010 - Courtney Kozul-Horvath, Dartmouth College 2009 - Karrie Radloff, Columbia University 2008 - Laura Senier, Brown University 2007 - Roxanne Karimi, Dartmouth College 2006 - Alicia R. Timme-Laragy, Duke University 2005 - Tiffany Bredfeldt, University of Arizona 2004 - Anne Spuches, Dartmouth College 2003 - Monica Mendez, University of Arizona 2002 - Elena Craft, Duke University 2001 - Blakely M. Adair, Texas Tech University 2000 - Angeline Andrew, Dartmouth College 1999 - Elisabeth Harrahy, Colorado State University 1998 - Sheila Healy, University of Arizona Annual Karen Wetterhahn Memorial Award Application Guidelines Trainee Videos What's New Where We Work Who We Fund Environmental Exposure Research Epidemiology Resources Health Impacts Research Institutional Research Training Researcher-Centered Stories of Success 2025 2024 2022 December 7, 2022 - Uncovering Relationships Between Air Pollution, Psychosocial Stressors, and Cardiovascular Disease September 1, 2022 - Combining Biostatics and Genomics Research to Prevent Disease August 23, 2022 - Embracing the Complexity of Environmental Health Challenges August 5, 2022 - Tracking Nanoparticles Across the Placental Barrier June 16, 2022 - Fleshing Out a Fungal Toxin’s Role in Liver Cancer May 2, 2022 - Exploring the Cardiovascular Effects of Arsenic Exposure April 13, 2022 - Visualizing DNA Damage Through a Molecular Lens April 19, 2022 - Uncovering the Link Between Metals and Disease April 19, 2022 - Preventing Disease Through Bioinformatics April 15, 2022 - Exploring the Role of the Biological Clock in Gene-environment Interactions March 11, 2022 - Connecting the Epigenome to Environmental Health February 17, 2022: Engaging Communities to Improve Well-being January 20, 2022 - Applying Novel Techniques to Understand Developmental Toxicity in Bone 2023 Time-Sensitive Research Opportunities in Environmental Health Translational Science, Outreach, and Education Community-engaged Research and Citizen Science Environmental Health Science Education Implementation Science in Environmental Health Partnerships for Environmental Public Health (PEPH) Research to Action Currently Funded Grantees A University-community Partnership to Reduce Exposure to Disinfection By-products in Appalachia Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents’ Concerns, Neurotoxic Effects, and Exposure Reduction Building Food Sovereignty, Sustainability, and Better Health in Environmentally Impacted Native Americans Collaborative Research and Action: Empowering an Exposed Community Community Action to Promote Healthy Environments El Trabajo no te Debe Dañar: Reduction of Hazardous Exposures in Small Businesses through a Community Health Worker Intervention Gigiigooinaan (Our Fish): A New Advisory to Promote Anishinaabe Health and Wellness Los Angeles Voices on Oil, Community, Environment, and Salud (LAS VOCES) Study PFAS-REACH (Research, Education, and Action for Community Health) Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska Radon on the RADAR Restoring Northeast Cape for the Health and Well-being of the Yupik Communities of St. Lawrence Island (Sivuqaq), Alaska Safe and Just Cleaners: Reducing Exposure to Toxic Cleaning Chemical Products Among Low-Wage Immigrant Latino Community Members The Salton Sea and Children’s Health: Assessing Imperial Valley Respiratory Health and the Environment Previously Funded Grantees Small Business Programs (SBIR/STTR) Virtual Consortium for Translational / Transdisciplinary Environmental Research (ViCTER) Worker Training Program What's New Initiatives Research Highlights Resources for Scientists Articles and Journals Bioethics Databases Electron Paramagnetic Resonance/Electron Spin Resonance (EPR/ESR) Glossaries International Myositis Assessment & Clinical Studies Group (IMACS) About the IMACS Mentorship Program About the Tools Classification Criteria Committees and Scientific Interest Groups Coordinators Disease Activity Core Set Measures Disease Damage Core Set Measures IMACS Studies Membership Myositis Response Criteria Other Tools Patient Reported Outcomes Program Updates April 14, 2006: IMACS Joins the International Myositis Classification Criteria Project April 2, 2021: Frederick W. Miller, M.D., Ph.D., Retirement April 6, 2021: Global Genes RARE Champion of Hope Awards February 1, 2005: IMACS trial outcomes data repository in development February 18, 2005: The Rituximab In Myositis (RIM) Study January 16, 2008: Classification Criteria Project open for data collection January 16, 2008: IMACS Outcomes Repository Open for Trial/Study Submissions January 7, 2011: Cure JM Wins Pepsi Challenge January 7, 2011: TMA Opens Myositis Patient Registry July 1, 2004: Preliminary definitions of improvement for myositis published June 1, 2012: Myositis Response Criteria to be Developed March 7, 2005: Investigative Opportunities in the RIM (Rituximab in Myositis) Study May 12, 2015: 1st International Myositis Conference May 5, 2017: 2nd Global Conference on Myositis October 18, 2006: IMACS Group Meeting 2006 October 27, 2008: IMACS Group Meeting 2008 October 28, 2007: IMACS Group Meeting 2007 October 3, 2005: IMACS Annual Meeting 2005 Publications - IMACS Publications - Related Registry Forms Repository Use Sponsors Websites of Interest Library & Information Services Protocols Seminars, Conferences, & Symposia Software Technology Transfer Training and Visual Guides Scientific Data Grants & Contracts Careers & Training News & Events About NIEHS Office of the Director Organizational Structure Strategic Plan 2025-2029 Advisory Boards & Councils Board of Scientific Counselors, Division of Intramural Research Board of Scientific Counselors, Division of Translational Toxicology Clinical Advisory Committee Environmental Health Sciences Review Committee Institutional Biosafety Committee National Advisory Environmental Health Sciences Council Agenda & Council Documents April 22, 2025 September 11-12, 2024 June 4, 2024 February 12-13, 2024 September 12-13, 2023 June 6-7, 2023 February 21-22, 2023 September 13-14, 2022 June 7-8, 2022 February 15-16, 2022 November 29, 2021 September 13, 2021 June 1-2, 2021 February 16-17, 2021 September 15-16, 2020 June 2, 2020 February 11-12, 2020 September 10-11, 2019 June 4-5, 2019 February 20-21, 2019 September 11-12, 2018 June 4-5, 2018 February 7 and February 12, 2018 October 3, 2017 September 13, 2017 June 6-7, 2017 February 14-15, 2017 September 13, 2016 May 24, 2016 February 23-24, 2016 September 9-10, 2015 June 2-3, 2015 February 19 and March 16, 2015 September 9-10, 2014 May 13-14, 2014 Meeting February 19-20, 2014 Meeting September 10-11, 2013 Meeting May 14-15, 2013 Meeting February 20-21, 2013 Meeting September 11, 2012 Meeting May 22-23, 2012 Meeting February 15-16, 2012 Meeting September 1-2, 2011 Meeting May 19-20, 2011 Meeting February 16-17, 2011 Meeting September 1-2, 2010 Meeting May 12-13, 2010 Meeting February 18-19, 2010 Meeting September 15-16, 2009 Meeting May 21-22, 2009 Meeting February 19, 2009 Meeting Resources that Highlight Impacts of NIEHS Research and Activities Council Members Community Involvement Congress Environmental Stewardship Freedom of Information Act History Milestones Timeline NIEHS 50th Anniversary NIH Office of History - NIEHS Interviews Papers of the Year Past Directors and Nobel Laureate Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Paul Kotin, M.D. Kenneth Olden, Ph.D. David P. Rall, M.D., Ph.D. David A. Schwartz, M.D., M.P.H. Nobel Laureate Martin Rodbell, Ph.D. Visiting NIEHS
Office of Scientific Computing
Lavender CA, Shapiro AJ, Day FS, Fargo DC. 2020. ORSO (Online Resource for Social Omics): A data-driven social network connecting scientists to genomics datasets. PLoS Comput Biol; doi: 10.1371/journal.pcbi.1007571 [Online 24 January 2020]. [Abstract Lavender CA, Shapiro AJ, Day FS, Fargo DC. 2020. ORSO (Online Resource for Social Omics): A data-driven social network connecting scientists to genomics datasets. PLoS Comput Biol; doi: 10.1371/journal.pcbi.1007571 [Online 24 January 2020]. ]
Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NSX, Czopik A, Shanahan MT, Kang A, Chen W, Azcarate-Peril MA, Gulati AS, Fargo DC, Guarente L, Li X. 2017. Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation during Aging in Mice by Altering the Intestinal Microbiota. Gastroenterology . S0016-5085, 35634-2. doi: 10.1053 [Epub ahead of print] [Abstract Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NSX, Czopik A, Shanahan MT, Kang A, Chen W, Azcarate-Peril MA, Gulati AS, Fargo DC, Guarente L, Li X. 2017. Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation during Aging in Mice by Altering the Intestinal Microbiota. Gastroenterology. S0016-5085, 35634-2. doi: 10.1053 [Epub ahead of print] ]
Lavender CA, Shapiro AJ, Burkholder AB, Bennett BD, Adelman K, Fargo DC. 2017. ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data. Nucleic Acids Res . 45, 5678-90. [Abstract Lavender CA, Shapiro AJ, Burkholder AB, Bennett BD, Adelman K, Fargo DC. 2017. ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data. Nucleic Acids Res. 45, 5678-90. ]
Lu J, Xu Q, Ji M, Guo X, Xu X, Fargo DC, Li X. 2017. The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice. EMBO Rep . 18, 841-57. [Abstract Lu J, Xu Q, Ji M, Guo X, Xu X, Fargo DC, Li X. 2017. The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice. EMBO Rep. 18, 841-57. ]
Ren NS, Ji M, Tokar EJ, Busch EL, Xu X, Lewis D, Li X, Jin A, Zhang Y, Wu WK, Huang W, Li L, Fargo DC, Keku TO, Sandler RS, Li X. 2017. Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development. Curr Biol . 27, 483-94. [Abstract Ren NS, Ji M, Tokar EJ, Busch EL, Xu X, Lewis D, Li X, Jin A, Zhang Y, Wu WK, Huang W, Li L, Fargo DC, Keku TO, Sandler RS, Li X. 2017. Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development. Curr Biol. 27, 483-94. ]
Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K. 2016. A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2. Stem Cell Rep . 6, 704-16. [Abstract Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K. 2016. A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2. Stem Cell Rep. 6, 704-16. ]
Zhou B, Wang L, Zhang S, Bennett BD, He F, Zhang Y, Xiong C, Han L, Diao L, Li P, Fargo DC, Cox AD, Hu G. 2016. INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma. Genes Dev . 30, 1440-53. [Abstract Zhou B, Wang L, Zhang S, Bennett BD, He F, Zhang Y, Xiong C, Han L, Diao L, Li P, Fargo DC, Cox AD, Hu G. 2016. INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma. Genes Dev. 30, 1440-53. ]
Wang T, Santos JH, Feng J, Cahill M, Fargo DC, Shen L, Nestler EJ, Woychik RP. 2016. A novel analytical strategy to identify fusion transcripts between repetitive elements and protein coding-exons using RNA-seq. PLoS One . e0159028. [Abstract Wang T, Santos JH, Feng J, Cahill M, Fargo DC, Shen L, Nestler EJ, Woychik RP. 2016. A novel analytical strategy to identify fusion transcripts between repetitive elements and protein coding-exons using RNA-seq. PLoS One. e0159028. ]
Bunch H, Lawney BP, Burkholder A, Ma D, Zheng X, Motola S, Fargo DC, Levine SS, Wang YE, Hu G. 2016. RNA polymerase II promoter-proximal pausing in mammalian long non-coding genes. Genomics . 108, 64-77. [Abstract Bunch H, Lawney BP, Burkholder A, Ma D, Zheng X, Motola S, Fargo DC, Levine SS, Wang YE, Hu G. 2016. RNA polymerase II promoter-proximal pausing in mammalian long non-coding genes. Genomics. 108, 64-77. ]
Lavender CA, Cannady KR, Hoffman JA, Trotter KW, Gilchrist DA, Bennett BD, Burkholder AB, Burd CJ, Fargo DC, Archer TK. 2016. Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters. PLoS Genet . e1006224. [Abstract Lavender CA, Cannady KR, Hoffman JA, Trotter KW, Gilchrist DA, Bennett BD, Burkholder AB, Burd CJ, Fargo DC, Archer TK. 2016. Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters. PLoS Genet. e1006224. ]
Zhang S, Zhou B, Wang L, Li P, Bennett BD, Snyder R, Garantziotis S, Fargo DC, Cox AD, Chen L, Hu G. 2016. INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer. Oncogene . 36, 1430-9. [Abstract Zhang S, Zhou B, Wang L, Li P, Bennett BD, Snyder R, Garantziotis S, Fargo DC, Cox AD, Chen L, Hu G. 2016. INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer. Oncogene. 36, 1430-9. ]
Zheng X, Yang P, Lackford B, Bennett BD, Wang L, Li H, Wang Y, Miao Y, Foley JF, Fargo DC, Jin Y, Williams CJ, Jothi R, Hu G. 2016. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports . 7, 897-910. [Abstract Zheng X, Yang P, Lackford B, Bennett BD, Wang L, Li H, Wang Y, Miao Y, Foley JF, Fargo DC, Jin Y, Williams CJ, Jothi R, Hu G. 2016. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports. 7, 897-910. ]
Saini N, SA Roberts, LJ Klimczak, K Chan, SA Grimm, S Dai, DC Fargo, JC Boyer, WK Kaufmann, JA Taylor, E Lee, I Cortes-Ciriano, PJ Park, SH Schurman, EP Malc, PA Mieczkowski, Gordenin DA. 2016. The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. PLoS Genet. e1006385. [Abstract Saini N, SA Roberts, LJ Klimczak, K Chan, SA Grimm, S Dai, DC Fargo, JC Boyer, WK Kaufmann, JA Taylor, E Lee, I Cortes-Ciriano, PJ Park, SH Schurman, EP Malc, PA Mieczkowski, Gordenin DA. 2016. The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. PLoS Genet. e1006385. ]
Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. 2015 An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat Genet . 47(9), 1067-72. [Abstract Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. 2015 An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat Genet. 47(9), 1067-72. ]
Scruggs BS, Gilchrist DA, Nechaev S, Muse GW, Burkholder A, Fargo DC, Adelman K. Mol Cell. 2015 Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin. Mol Cell 58(6):1101-12. [Abstract Scruggs BS, Gilchrist DA, Nechaev S, Muse GW, Burkholder A, Fargo DC, Adelman K. Mol Cell. 2015 Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin. Mol Cell 58(6):1101-12. ]
Williams LH, Fromm G, Gokey NG, Henriques T, Muse GW, Burkholder A, Fargo DC, Hu G, Adelman K. 2015 Pausing of RNA polymerase II Regulates Mammalian Developmental Potential. Mol Cell . 58(2), 311-22. [Abstract Williams LH, Fromm G, Gokey NG, Henriques T, Muse GW, Burkholder A, Fargo DC, Hu G, Adelman K. 2015 Pausing of RNA polymerase II Regulates Mammalian Developmental Potential. Mol Cell. 58(2), 311-22. ]
Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. 2015 Tracking DNA replication enzymology in vivo using ribonucleotides Nat Struct Mol Biol . 22(3), 185-91. [Abstract Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. 2015 Tracking DNA replication enzymology in vivo using ribonucleotides Nat Struct Mol Biol. 22(3), 185-91. ]
Wells ML, Washington OL, Hicks SN, Nobile CJ, Hartooni N, Wilson GM, Zucconi BE, Huang W, Li L, Fargo DC, Blackshear PJ. 2014 Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans . Mol Microbiol . 95,1036-53. [Abstract Wells ML, Washington OL, Hicks SN, Nobile CJ, Hartooni N, Wilson GM, Zucconi BE, Huang W, Li L, Fargo DC, Blackshear PJ. 2014 Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans. Mol Microbiol. 95,1036-53. ]
Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. 2014 Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. Genome Res . 24, 1751-64. [Abstract Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. 2014 Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. Genome Res. 24, 1751-64. ]
Bunch H, Zheng X, Burkholder A, Dillon ST, Motola S, Birrane G, Ebmeier CC, Levine S, Fargo D, Hu G, Taatjes DJ, Calderwood SK. 2014 TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nat Struct Mol Biol . 21, 876-83. [Abstract Bunch H, Zheng X, Burkholder A, Dillon ST, Motola S, Birrane G, Ebmeier CC, Levine S, Fargo D, Hu G, Taatjes DJ, Calderwood SK. 2014 TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nat Struct Mol Biol. 21, 876-83. ]
Davis CF, et al. (with Gordenin DA, Roberts SA, Klimczak LJ, Fargo D). 2014 The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma. Cancer Cell . 26, 319-30 [Abstract Davis CF, et al. (with Gordenin DA, Roberts SA, Klimczak LJ, Fargo D). 2014 The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma. Cancer Cell. 26, 319-30 ]
Tang S, Huang G, Fan W, Chen Y, Ward JM, Xu X, Xu Q, Kang A, McBurney MW, Fargo DC, Hu G, Baumgart-Vogt E, Zhao Y, Li X. 2014 SIRT1-Mediated Deacetylation of CRABPII Regulates Cellular Retinoic Acid Signaling and Modulates Embryonic Stem Cell Differentiation. Mol Cell . 55, 843-55. [Abstract Tang S, Huang G, Fan W, Chen Y, Ward JM, Xu X, Xu Q, Kang A, McBurney MW, Fargo DC, Hu G, Baumgart-Vogt E, Zhao Y, Li X. 2014 SIRT1-Mediated Deacetylation of CRABPII Regulates Cellular Retinoic Acid Signaling and Modulates Embryonic Stem Cell Differentiation. Mol Cell. 55, 843-55. ]
Wang L, Du Y, Ward JM, Shimbo T, Lackford B, Zheng X, Miao Y, Zhou B, Han L, Fargo DC, Jothi R, Williams CJ, Wade PA, Hu G. 2014 INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-Renewal, Reprogramming, and Blastocyst Development. Cell Stem Cell . 14, 575–591. [Abstract Wang L, Du Y, Ward JM, Shimbo T, Lackford B, Zheng X, Miao Y, Zhou B, Han L, Fargo DC, Jothi R, Williams CJ, Wade PA, Hu G. 2014 INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-Renewal, Reprogramming, and Blastocyst Development. Cell Stem Cell. 14, 575–591. ]
Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, Demayo FJ, Schütz G, Korach KS. 2014 Unexpected Hormone Response Motif Activity of Female Estrogen Receptor α DNA Binding Deficient Mouse. Mol Endocrinol . 28, 899-911. [Abstract Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, Demayo FJ, Schütz G, Korach KS. 2014 Unexpected Hormone Response Motif Activity of Female Estrogen Receptor α DNA Binding Deficient Mouse. Mol Endocrinol. 28, 899-911. ]
Weinstein JN, et al. (with Gordenin DA, Fargo D, Klimczak LJ, Roberts SA). 2014 Comprehensive molecular characterization of urothelial bladder carcinoma. Nature . 20, 315-22. [Abstract Weinstein JN, et al. (with Gordenin DA, Fargo D, Klimczak LJ, Roberts SA). 2014 Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 20, 315-22. ]
Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G. 2013 The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming. Cell Stem Cell . 13, 676-90. [Abstract Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G. 2013 The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming. Cell Stem Cell. 13, 676-90. ]
Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K. 2013 Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals. Mol Cell . 52, 517-28. [Abstract Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K. 2013 Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals. Mol Cell. 52, 517-28. ]
Huang W, Loganantharaj R, Schroeder B, Fargo D, Li L. 2013 PAVIS: a tool for Peak Annotation and Visualization. Bioinformatics . 29, 3097-9. [Abstract Huang W, Loganantharaj R, Schroeder B, Fargo D, Li L. 2013 PAVIS: a tool for Peak Annotation and Visualization. Bioinformatics. 29, 3097-9. ]
Lai WS, Stumpo DJ, Kennington EA, Burkholder AB, Ward JM, Fargo D, Blackshear PJ. 2013 Life without TTP: apparent absence of an important anti-inflammatory protein in birds. Am J Physiol Regul Integr Comp Physiol . 305, 689-700. [Abstract Lai WS, Stumpo DJ, Kennington EA, Burkholder AB, Ward JM, Fargo D, Blackshear PJ. 2013 Life without TTP: apparent absence of an important anti-inflammatory protein in birds. Am J Physiol Regul Integr Comp Physiol. 305, 689-700. ]
Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA. 2013 An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet . 45, 970-6. [Abstract Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA. 2013 An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet. 45, 970-6. ]
Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT. 2012 Defining the status of RNA polymerase at promoters. Cell Rep . 2:1025-35. [Abstract Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT. 2012 Defining the status of RNA polymerase at promoters. Cell Rep. 2:1025-35. ]
Wells ML, Huang W, Li L, Gerrish KE, Fargo DC, Ozsolak F, Blackshear PJ. 2012 Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe. Mol Cell Biol . 32, 4206-14. [Abstract Wells ML, Huang W, Li L, Gerrish KE, Fargo DC, Ozsolak F, Blackshear PJ. 2012 Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe. Mol Cell Biol. 32, 4206-14. ]
Gilchrist DA, Fromm G, Dos Santos G, Pham LN, McDaniel IE, Burkholder A, Fargo DC, Adelman K. 2012 Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks. Genes Dev . 26, 933-44. [Abstract Gilchrist DA, Fromm G, Dos Santos G, Pham LN, McDaniel IE, Burkholder A, Fargo DC, Adelman K. 2012 Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks. Genes Dev. 26, 933-44. ]
Hewitt SC, Li L, Grimm SA, Chen Y, Liu L, Li Y, Bushel PR, Fargo D, Korach KS. 2012 Research Resource: Whole-Genome Estrogen Receptor α Binding in Mouse Uterine Tissue Revealed by ChIP-Seq. Mol Endocrinol . 26, 887-98. [Abstract Hewitt SC, Li L, Grimm SA, Chen Y, Liu L, Li Y, Bushel PR, Fargo D, Korach KS. 2012 Research Resource: Whole-Genome Estrogen Receptor α Binding in Mouse Uterine Tissue Revealed by ChIP-Seq. Mol Endocrinol. 26, 887-98. ]
Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang JY, Daigle KR, Fenn JD, Adelman K, Dudek SM. 2011 Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II. Nat Neurosci . 14, 848-56. [Abstract Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang JY, Daigle KR, Fenn JD, Adelman K, Dudek SM. 2011 Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II. Nat Neurosci. 14, 848-56. ]
Colaneri A, Staffa N, Fargo DC, Gao Y, Wang T, Peddada SD, Birnbaumer L. 2011 Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome. Proc Natl Acad Sci U S A . 108, 9715-20. [Abstract Colaneri A, Staffa N, Fargo DC, Gao Y, Wang T, Peddada SD, Birnbaumer L. 2011 Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome. Proc Natl Acad Sci U S A. 108, 9715-20. ]
Gilchrist DA, Dos Santos G, Fargo DC, Xie B, Gao Y, Li L, Adelman K. 2010 Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation. Cell . 143, 540-51. [Abstract Gilchrist DA, Dos Santos G, Fargo DC, Xie B, Gao Y, Li L, Adelman K. 2010 Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation. Cell. 143, 540-51. ]
Stajich JE, Wilke SK, Ahrén D, Au CH, Birren BW, Borodovsky M, Burns C, Canbäck B, Casselton LA, Cheng CK, Deng J, Dietrich FS, Fargo DC, Farman ML, Gathman AC, Goldberg J, Guigó R, Hoegger PJ, Hooker JB, Huggins A, James TY, Kamada T, Kilaru S, Kodira C, Kües U, Kupfer D, Kwan HS, Lomsadze A, Li W, Lilly WW, Ma LJ, Mackey AJ, Manning G, Martin F, Muraguchi H, Natvig DO, Palmerini H, Ramesh MA, Rehmeyer CJ, Roe BA, Shenoy N, Stanke M, Ter-Hovhannisyan V, Tunlid A, Velagapudi R, Vision TJ, Zeng Q, Zolan ME, Pukkila PJ 2010 Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus ). Proc Natl Acad Sci U S A . 107, 11889-94. [Abstract Stajich JE, Wilke SK, Ahrén D, Au CH, Birren BW, Borodovsky M, Burns C, Canbäck B, Casselton LA, Cheng CK, Deng J, Dietrich FS, Fargo DC, Farman ML, Gathman AC, Goldberg J, Guigó R, Hoegger PJ, Hooker JB, Huggins A, James TY, Kamada T, Kilaru S, Kodira C, Kües U, Kupfer D, Kwan HS, Lomsadze A, Li W, Lilly WW, Ma LJ, Mackey AJ, Manning G, Martin F, Muraguchi H, Natvig DO, Palmerini H, Ramesh MA, Rehmeyer CJ, Roe BA, Shenoy N, Stanke M, Ter-Hovhannisyan V, Tunlid A, Velagapudi R, Vision TJ, Zeng Q, Zolan ME, Pukkila PJ 2010 Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). Proc Natl Acad Sci U S A. 107, 11889-94. ]
Nechaev S, Fargo DC, dos Santos G, Liu L, Gao Y, Adelman K. 2010 Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila. Science . 327, 335-8. [Abstract Nechaev S, Fargo DC, dos Santos G, Liu L, Gao Y, Adelman K. 2010 Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila. Science. 327, 335-8. ]
Gilchrist DA, Fargo DC, Adelman K. 2009 Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation. Methods. 4, 398-408. [Abstract Gilchrist DA, Fargo DC, Adelman K. 2009 Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation. Methods. 4, 398-408. ]
Back to Top
Last Reviewed: September 08, 2020