Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Division of Intramural Research (DIR)
Epigenetics and Stem Cell Biology Laboratory (ESCBL)
Research Triangle Park, North Carolina

The Epigenetics & Stem Cell Biology Laboratory (ESCBL) of the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, North Carolina is recruiting a Director for the Epigenomics and DNA Sequencing Core Facility. The mission of NIEHS is to discover how the environment affects people in order to promote healthier lives. In support of this mission, ESCBL investigates fundamental mechanisms by which epigenetics — non-genetic modulation and alterations — influences chromatin architecture, transcription and gene expression in normal, cancer and stem cells, and provides insights into biological processes that modulate the effects of environmental exposures on human development and health.

The Epigenomics and DNA sequencing core facility in ESCBL provides NIEHS investigators on-site quick access to next-generation sequencing (NGS) technologies, such as RNA-seq, ATAC-seq, ChIP-seq, Cut&Tag/Run, WGS, WGBS, scRNA-seq, scMultiome, Spatial transcriptomics, CITE-seq, Perturb-seq, Nanopore RNA and DNA sequencing, and PacBio sequencing, in order to address their research questions. We are seeking a Ph.D.-level scientist with comprehensive understanding of and experience with NGS and related technologies to direct and manage the core facility. The director will be a NIH employee appointed to a time-limited, renewable position to support the long-term research of the Epigenomics and DNA sequencing core facility.


  1. Ph.D. or equivalent degree in molecular biology or related fields with 3+ years of postdoctoral experience is required.
  2. Knowledge and experience in NGS and genomics technologies, as demonstrated by relevant publications, is required.
  3. Excellent oral and written communication skills are required.
  4. Experience with different NGS platforms (Illumina, Nanopore, PacBio, etc.), laboratory automation, epigenetics, or genetics is strongly preferred.
  5. Experience in leadership, management, and teamwork is highly desired.


Responsibilities include but are not limited to:

  • Develop and maintain standard operation protocols.
  • Establish contracts and partnerships with commercial vendors.
  • Establish new or customized NGS methods and applications.
  • Manage and supervise core personnel.
  • Provide technical consultations to NIEHS investigators.


The successful candidate for this position will be appointed at a salary commensurate with experience and accomplishments with full Federal benefits.

How to Apply

Review of applications for the position will begin on June 3, 2024. Interested candidates must submit all materials specified below as one combined PDF via email to Bonnie J. Earnhardt. Include the vacancy number NR152 in the subject line.

A complete application includes:

  1. Curriculum Vitae: Include your full curriculum vitae and bibliography. Please include a description of mentoring and outreach activities, especially activities with women or other underrepresented groups in biomedical sciences.
  2. Research Statement: Include a two-page statement of research background and interests.
  3. DEIA Statement: Include a statement, not to exceed 1 page, which addresses your commitment to Diversity, Equity, Inclusion, and Accessibility.

In addition, you must also arrange for three letters of reference to be sent directly to Intramural Applications. Letters should be on official letterhead, signed, and dated. Referees must include the applicant’s name and vacancy number NR152 in the email subject line. Incomplete applications or paper applications will not be accepted.

Questions about this position can be forwarded to Guang Hu, Ph.D. The search will remain open until the position is filled.

Commitment to Diversity and Equal Employment Opportunity

NIH/NIEHS encourages the application and nomination of qualified women, minorities, and individuals with disabilities. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factors. NIH/NIEHS will provide reasonable accommodations to applicants with disabilities as appropriate. If you require reasonable accommodation during any part of the application and hiring process, please notify us.

Equal Opportunity Employment

Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities.

Foreign Education

Applicants who have completed part or all their education outside of the US must have their foreign education evaluated by an accredited organization to ensure that the foreign education is equivalent to education received in accredited educational institutions in the United States. We will only accept the completed foreign education evaluation. For more information on foreign education verification, visit the National Association of Credential Evaluation Services (NACES). Verification must be received prior to the effective date of the appointment.

NIH is dedicated to building a diverse community in its training and employment programs. DHHS and NIH are Equal Opportunity Employers. Applications from women, minorities, and persons with disabilities are strongly encouraged.

Do not include your birth date or social security number (SSN) on application materials.

DHHS and NIH are equal opportunity employers.