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Your Environment. Your Health.

Mixtures

Program Leads

Danielle Carlin, Ph.D.
Danielle Carlin, Ph.D., D.A.B.T.
Health Scientist Administrator
PO Box 12233
Research Triangle Park, NC 27709
Office located in: Keystone Office Bldg.
530 Davis Drive
Morrisville, NC 27560
Tel (919) 541-1409
Fax (919) 541-2843
danielle.carlin@nih.gov
Claudia Thompson
Claudia L. Thompson, Ph.D.
Chief, Susceptibility and Population Health Branch
Tel (919) 541-4638
Fax (919) 316-4606
thomps14@niehs.nih.gov
PO Box 12233
Research Triangle Park, NC 27709
Office located in: Keystone Office Bldg.
530 Davis Drive
Morrisville, NC 27560

 

Program Description

 

People are exposed to a multitude of environmental toxicants.  Scientists are working to understand the implications of these chemical mixtures, which can sometimes produce health effects greater than each chemical would alone.

 

For example, exposure to ozone and aldehydes, which are components of smog, produces greater health effects than would be predicted based on each chemical. Also, smokers who are also exposed to radon or asbestos have a greater risk of developing lung cancer. 

 

What NIEHS is doing

 

Most exposure research has studied the health effects of single chemicals at specific times, but environmental health scientists are developing methods to study environmental exposures in ways that more closely represent the mixture of exposures that we actually experience. They are examining how these mixtures interact in in vitro and in vivo systems and in humans to determine health effects; developing better mathematical tools for risk assessment; characterizing real-life mixtures; and, assessing exposures by studying how mixtures are transported in the environment.

 

For additional information on what NIEHS grantees are doing, visit our Who We Fund tool.

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