Danielle J. Carlin, Ph.D.
Health Scientist Administrator
530 Davis Dr
Durham, NC 27713
Tel (919) 541-1409
Claudia Thompson, Ph.D.
Chief, Susceptibility and Population Health Branch
People are exposed to a multitude of environmental toxicants. Scientists are working to understand the implications of these chemical mixtures, which can sometimes produce health effects greater than each chemical would alone.
For example, exposure to ozone and aldehydes, which are components of smog, produces greater health effects than would be predicted based on each chemical. Also, smokers who are also exposed to radon or asbestos have a greater risk of developing lung cancer.
What NIEHS is doing
Most exposure research has studied the health effects of single chemicals at specific times, but environmental health scientists are developing methods to study environmental exposures in ways that more closely represent the mixture of exposures that we actually experience. They are examining how these mixtures interact in in vitro and in vivo systems and in humans to determine health effects; developing better mathematical tools for risk assessment; characterizing real-life mixtures; and, assessing exposures by studying how mixtures are transported in the environment.
For additional information on what NIEHS grantees are doing, visit our Who We Fund tool.